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The map label for this gene is engA [H]

Identifier: 88607492

GI number: 88607492

Start: 403003

End: 404325

Strand: Reverse

Name: engA [H]

Synonym: APH_0390

Alternate gene names: 88607492

Gene position: 404325-403003 (Counterclockwise)

Preceding gene: 88606767

Following gene: 88606996

Centisome position: 27.48

GC content: 40.59

Gene sequence:

>1323_bases
ATGCAAAAAGTGGCTATAGTTGGGTTACCCAATGTAGGGAAATCTACTTTATTTAACCGTCTAACAAGAAGGAAATCTGC
AATAGTCAGCGATATAGCTCATGTTACTCGTGATAGAAAAGAAGCCTTAGTAGACTTTTGTGGACTGCGGTTTATAGCCA
TAGATACAGGCGGCGTTGCGGACGGAGGTGAAATACAGTCATTAGTAAAAACGCAGGTGCAACTCGCACTTGAAAATGCC
GACGTTGTGCTATTTGTGATAGATGCCCAACGCGCTACAGATTCCCACAGCACATCTCTAGGCAAATGGCTAAGCAAGAT
AACTAACAAACCCATAATCTTAGTAGCTAATAAATGTGAAAGTAATAAAAACAATGTCCACGTGGATACAATGGAATATC
TAGGGTTCCTTGGACCTGTGTACATATCTGCAGAACATAACTTGGGCATGGCAGATTTATATGAAGCTATTGCCCCATTA
ATAGAACAGAGTGAAAGGCCTAAAAAAGACCAAGATCGCCCAATAGCAATTTCTATAATAGGCCAGCCTAATGTGGGGAA
GTCAACATTTGTGAACAGTATTTTAGGCGAAGAGAGAGTAATAACAAGTGGTATAGCAGGCACTACTCGTGATTCCATAA
GCGCTGAATATTCTTATAAGGGCATCACGCTACTGTTGACTGATACTGCAGGCATTCGCAAGCGTACAAAAGTAACTGAG
AACATGGAGAAACTTTCCGTACAGTCTGCAATCCATGCATTATCAAAATCACATGTAGTAATATTAATAGTAGACTTCAC
ACAAGGCATCAGCCAACAGGATCTCTCCATAGCAAGCACCGCAATAAAAGACGGAAAAGGTATTGTTTTGGCGCTAAATA
AAGCTGACCTTGTAAACGATAAAGCCGCAGAAGACGCAATCTTAAACGCAATACGGCAGTACAGCAGAGTCGACTTTGAT
GTTCCTATCATGAAGATGTCCGCACTAGAAAATATTGGATGCGATAAGGTTCTAAGTAAGGCTGTAAAAATATATGAGTC
CGCAAGCACACACATAAGTACTTCGAAACTTAATAAGTGGCTTGGTACAGCTATAGACTACCACCCTCCACATTTGCAAA
ATAAGAAAAAAGTCAGGCTAAAATACATATCGCAAGTTAGCACACTGCCCCCCACCTTCGTAATAGCTACAAACAGTACA
GAGGTGGAAAGTACTTATCAAACGTATCTGAAAAACAGCTTCCTAAAACATTTTTCCATGCAAGGTGTCCCCATAAGGAT
GATTTTCAAGAAGGGTAACAATCCCTATATCTCCAAAGACTAG

Upstream 100 bases:

>100_bases
CAATGCAATGCTTCTTTAGTAATAAGACATATGCAGCTTCACACTTGTGATATTGTAGGTATAATCCTTGAACAAGTGAT
TCTATACATTGGTATTATAA

Downstream 100 bases:

>100_bases
CGCCAAATCTGGCAATCTTATCGGCGGTTTCAAGCTACATGTCCTATAACTTCGCAACAACAGGCCCTCACAATACGCAA
TTTGGATTGCAATCCCTCGG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQKVAIVGLPNVGKSTLFNRLTRRKSAIVSDIAHVTRDRKEALVDFCGLRFIAIDTGGVADGGEIQSLVKTQVQLALENA
DVVLFVIDAQRATDSHSTSLGKWLSKITNKPIILVANKCESNKNNVHVDTMEYLGFLGPVYISAEHNLGMADLYEAIAPL
IEQSERPKKDQDRPIAISIIGQPNVGKSTFVNSILGEERVITSGIAGTTRDSISAEYSYKGITLLLTDTAGIRKRTKVTE
NMEKLSVQSAIHALSKSHVVILIVDFTQGISQQDLSIASTAIKDGKGIVLALNKADLVNDKAAEDAILNAIRQYSRVDFD
VPIMKMSALENIGCDKVLSKAVKIYESASTHISTSKLNKWLGTAIDYHPPHLQNKKKVRLKYISQVSTLPPTFVIATNST
EVESTYQTYLKNSFLKHFSMQGVPIRMIFKKGNNPYISKD

Sequences:

>Translated_440_residues
MQKVAIVGLPNVGKSTLFNRLTRRKSAIVSDIAHVTRDRKEALVDFCGLRFIAIDTGGVADGGEIQSLVKTQVQLALENA
DVVLFVIDAQRATDSHSTSLGKWLSKITNKPIILVANKCESNKNNVHVDTMEYLGFLGPVYISAEHNLGMADLYEAIAPL
IEQSERPKKDQDRPIAISIIGQPNVGKSTFVNSILGEERVITSGIAGTTRDSISAEYSYKGITLLLTDTAGIRKRTKVTE
NMEKLSVQSAIHALSKSHVVILIVDFTQGISQQDLSIASTAIKDGKGIVLALNKADLVNDKAAEDAILNAIRQYSRVDFD
VPIMKMSALENIGCDKVLSKAVKIYESASTHISTSKLNKWLGTAIDYHPPHLQNKKKVRLKYISQVSTLPPTFVIATNST
EVESTYQTYLKNSFLKHFSMQGVPIRMIFKKGNNPYISKD
>Mature_440_residues
MQKVAIVGLPNVGKSTLFNRLTRRKSAIVSDIAHVTRDRKEALVDFCGLRFIAIDTGGVADGGEIQSLVKTQVQLALENA
DVVLFVIDAQRATDSHSTSLGKWLSKITNKPIILVANKCESNKNNVHVDTMEYLGFLGPVYISAEHNLGMADLYEAIAPL
IEQSERPKKDQDRPIAISIIGQPNVGKSTFVNSILGEERVITSGIAGTTRDSISAEYSYKGITLLLTDTAGIRKRTKVTE
NMEKLSVQSAIHALSKSHVVILIVDFTQGISQQDLSIASTAIKDGKGIVLALNKADLVNDKAAEDAILNAIRQYSRVDFD
VPIMKMSALENIGCDKVLSKAVKIYESASTHISTSKLNKWLGTAIDYHPPHLQNKKKVRLKYISQVSTLPPTFVIATNST
EVESTYQTYLKNSFLKHFSMQGVPIRMIFKKGNNPYISKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=473, Percent_Identity=37.8435517970402, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI2367268, Length=246, Percent_Identity=25.2032520325203, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788919, Length=209, Percent_Identity=27.7511961722488, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=178, Percent_Identity=32.0224719101124, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48315; Mature: 48315

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVAIVGLPNVGKSTLFNRLTRRKSAIVSDIAHVTRDRKEALVDFCGLRFIAIDTGGVA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
DGGEIQSLVKTQVQLALENADVVLFVIDAQRATDSHSTSLGKWLSKITNKPIILVANKCE
CCHHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCC
SNKNNVHVDTMEYLGFLGPVYISAEHNLGMADLYEAIAPLIEQSERPKKDQDRPIAISII
CCCCCEEEEHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GQPNVGKSTFVNSILGEERVITSGIAGTTRDSISAEYSYKGITLLLTDTAGIRKRTKVTE
CCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHH
NMEKLSVQSAIHALSKSHVVILIVDFTQGISQQDLSIASTAIKDGKGIVLALNKADLVND
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHCCC
KAAEDAILNAIRQYSRVDFDVPIMKMSALENIGCDKVLSKAVKIYESASTHISTSKLNKW
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGTAIDYHPPHLQNKKKVRLKYISQVSTLPPTFVIATNSTEVESTYQTYLKNSFLKHFSM
HHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
QGVPIRMIFKKGNNPYISKD
CCCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MQKVAIVGLPNVGKSTLFNRLTRRKSAIVSDIAHVTRDRKEALVDFCGLRFIAIDTGGVA
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
DGGEIQSLVKTQVQLALENADVVLFVIDAQRATDSHSTSLGKWLSKITNKPIILVANKCE
CCHHHHHHHHHHHHHEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCC
SNKNNVHVDTMEYLGFLGPVYISAEHNLGMADLYEAIAPLIEQSERPKKDQDRPIAISII
CCCCCEEEEHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GQPNVGKSTFVNSILGEERVITSGIAGTTRDSISAEYSYKGITLLLTDTAGIRKRTKVTE
CCCCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEECCEEEEEECCCCCHHHHHHHH
NMEKLSVQSAIHALSKSHVVILIVDFTQGISQQDLSIASTAIKDGKGIVLALNKADLVND
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHCCC
KAAEDAILNAIRQYSRVDFDVPIMKMSALENIGCDKVLSKAVKIYESASTHISTSKLNKW
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGTAIDYHPPHLQNKKKVRLKYISQVSTLPPTFVIATNSTEVESTYQTYLKNSFLKHFSM
HHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
QGVPIRMIFKKGNNPYISKD
CCCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA