Click here to switch to the map view.

The map label for this gene is nuoA [H]

Identifier: 88607210

GI number: 88607210

Start: 540417

End: 540779

Strand: Direct

Name: nuoA [H]

Synonym: APH_0519

Alternate gene names: 88607210

Gene position: 540417-540779 (Clockwise)

Preceding gene: 88607944

Following gene: 88607775

Centisome position: 36.73

GC content: 40.5

Gene sequence:

>363_bases
GTGTTTGATGTTGGAGAGTACTCTTCAGTTTTGATCTTTTTCTCGCTTGCAGCGGTGCTATCTTCGCTCTTTGCCGTTTT
ACCGATCTTTTTAGCAAAGCGTAGGGATTCTATGGAGAAGTTAGTTCCTTACGAGTGCGGGTTTGATCAAAAGGAGGAGG
TAAGTTCTGTATTTGATATCAAGTTTTGTATTATCGGGATTTTATTTGTGATCTTTGATGTTGAGGTCACTTTTCTTTTT
CCCTGGTCGGTATGCTTAGGTAGCATTGGTTTTGCGGGGTATTTTTCGATGCTATGTTTCCTGGGAATGCTAACTATCGG
TTTTATATACGAATGGAATAGTGGTGCCTTAGAATGGGAGTAG

Upstream 100 bases:

>100_bases
ATTCAGTAGTAGTCGTTAGGCGTAGTATGCTTTATCAAAAATTGACATTTTAAAGGAAATTAGTCACAATTCGGTGATAT
ACTCTAGGTGATATATTTGC

Downstream 100 bases:

>100_bases
GCATGGGTGAATGTGATCAGATACTAGAAAATGATCTATGGCAGGGCTATAAGGATCAGGGTTTTGTGGTAACGCAATTC
TCGGACCTAATAGAGAGAGT

Product: NADH dehydrogenase I, A subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MFDVGEYSSVLIFFSLAAVLSSLFAVLPIFLAKRRDSMEKLVPYECGFDQKEEVSSVFDIKFCIIGILFVIFDVEVTFLF
PWSVCLGSIGFAGYFSMLCFLGMLTIGFIYEWNSGALEWE

Sequences:

>Translated_120_residues
MFDVGEYSSVLIFFSLAAVLSSLFAVLPIFLAKRRDSMEKLVPYECGFDQKEEVSSVFDIKFCIIGILFVIFDVEVTFLF
PWSVCLGSIGFAGYFSMLCFLGMLTIGFIYEWNSGALEWE
>Mature_120_residues
MFDVGEYSSVLIFFSLAAVLSSLFAVLPIFLAKRRDSMEKLVPYECGFDQKEEVSSVFDIKFCIIGILFVIFDVEVTFLF
PWSVCLGSIGFAGYFSMLCFLGMLTIGFIYEWNSGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=116, Percent_Identity=32.7586206896552, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13611; Mature: 13611

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDVGEYSSVLIFFSLAAVLSSLFAVLPIFLAKRRDSMEKLVPYECGFDQKEEVSSVFDI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KFCIIGILFVIFDVEVTFLFPWSVCLGSIGFAGYFSMLCFLGMLTIGFIYEWNSGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFDVGEYSSVLIFFSLAAVLSSLFAVLPIFLAKRRDSMEKLVPYECGFDQKEEVSSVFDI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KFCIIGILFVIFDVEVTFLFPWSVCLGSIGFAGYFSMLCFLGMLTIGFIYEWNSGALEWE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA