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The map label for this gene is frr [H]

Identifier: 88607028

GI number: 88607028

Start: 118458

End: 119012

Strand: Direct

Name: frr [H]

Synonym: APH_0112

Alternate gene names: 88607028

Gene position: 118458-119012 (Clockwise)

Preceding gene: 88607790

Following gene: 88607896

Centisome position: 8.05

GC content: 43.42

Gene sequence:

>555_bases
GTGGCTACTGGAGCGATTAGGCAATATGCTCAAGAGAGGATGGACAAGACTTATGCCATGTTCTTGAATGACATATCGGG
TATACGGACAGGAAGGGTGAGTGCGTCGTTGTTGGACGGTATTTCTGTCAGTTACTACGGCAATAAGGTGAAATTGAACA
CAGTTTCTAGCATATCGGTAAATGGTCGTACGCTGTTGGTTTCTCTTTGGGATGCTAGTATTCTAGGAGAGGTGAAGTCG
GCTATTGAAGCTTCTAACATGGGATTTGGTATGACGTGTGAGTCAAGTACTGTTAGGCTTGTCGTTCCTGAGCTCACGAA
TGATGTGCGGAAGAACTTGGTTAAAATGCTGAACAAACTCGCTGAGGAGAGCAAGGTTTCTATACGTAACATCAGGAGAG
ATGCCATAGAGAGGCTGAAGTCTCTGCAAGATAACAAAGAAATATCAGAAGATGACATGCATGGTGTTAGTGCGGAAATC
CAGAAAATTACCGATTCTTTTATCAAGAAAATTGCCGATGCTTATACCAGCAAGGAAAGTGAGATCCTAGGTTAG

Upstream 100 bases:

>100_bases
CTATTCCTATAATTGTGTTTGATCTAGGGAAAGAGAATGCTTTTTCGGAAGTGATGAAGGGAAGGGGTACGTTTACTACT
ATATCTGGATAGGAGGGGAA

Downstream 100 bases:

>100_bases
AAGGGCGAGGAGTATTCTTTATCCTTGGGTTATATAGGTTGCTTAGGTGTATTGCATTGCAATATGGCTTCAAAGCGCGC
GGGTGTTGCTGGCCAGAATC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MATGAIRQYAQERMDKTYAMFLNDISGIRTGRVSASLLDGISVSYYGNKVKLNTVSSISVNGRTLLVSLWDASILGEVKS
AIEASNMGFGMTCESSTVRLVVPELTNDVRKNLVKMLNKLAEESKVSIRNIRRDAIERLKSLQDNKEISEDDMHGVSAEI
QKITDSFIKKIADAYTSKESEILG

Sequences:

>Translated_184_residues
MATGAIRQYAQERMDKTYAMFLNDISGIRTGRVSASLLDGISVSYYGNKVKLNTVSSISVNGRTLLVSLWDASILGEVKS
AIEASNMGFGMTCESSTVRLVVPELTNDVRKNLVKMLNKLAEESKVSIRNIRRDAIERLKSLQDNKEISEDDMHGVSAEI
QKITDSFIKKIADAYTSKESEILG
>Mature_183_residues
ATGAIRQYAQERMDKTYAMFLNDISGIRTGRVSASLLDGISVSYYGNKVKLNTVSSISVNGRTLLVSLWDASILGEVKSA
IEASNMGFGMTCESSTVRLVVPELTNDVRKNLVKMLNKLAEESKVSIRNIRRDAIERLKSLQDNKEISEDDMHGVSAEIQ
KITDSFIKKIADAYTSKESEILG

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Escherichia coli, GI1786368, Length=179, Percent_Identity=44.1340782122905, Blast_Score=151, Evalue=3e-38,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20316; Mature: 20184

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGAIRQYAQERMDKTYAMFLNDISGIRTGRVSASLLDGISVSYYGNKVKLNTVSSISV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCEEEEEEECEEEE
NGRTLLVSLWDASILGEVKSAIEASNMGFGMTCESSTVRLVVPELTNDVRKNLVKMLNKL
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHH
AEESKVSIRNIRRDAIERLKSLQDNKEISEDDMHGVSAEIQKITDSFIKKIADAYTSKES
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EILG
CCCC
>Mature Secondary Structure 
ATGAIRQYAQERMDKTYAMFLNDISGIRTGRVSASLLDGISVSYYGNKVKLNTVSSISV
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCEEEEEEECEEEE
NGRTLLVSLWDASILGEVKSAIEASNMGFGMTCESSTVRLVVPELTNDVRKNLVKMLNKL
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHH
AEESKVSIRNIRRDAIERLKSLQDNKEISEDDMHGVSAEIQKITDSFIKKIADAYTSKES
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EILG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA