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The map label for this gene is elbB [H]

Identifier: 88606844

GI number: 88606844

Start: 7046

End: 7711

Strand: Direct

Name: elbB [H]

Synonym: APH_0006

Alternate gene names: 88606844

Gene position: 7046-7711 (Clockwise)

Preceding gene: 88607386

Following gene: 88606947

Centisome position: 0.48

GC content: 39.94

Gene sequence:

>666_bases
ATGAATTGCGCTGTACTTTTATGTGGATGCGGGCACATGGACGGCTCAGAGATAAGAGAGGCTGTGCTTGCTCTGTTAGC
GCTTGATTCCTATGGAATAAATGTTACTTGCTGTGCTCCTAATATTAAGCAAGTAGATGTTGTAGACCACTTGAGTGGCT
CTACTCTTGAAGAAGAAAGGGATATAATGTCGGAATCTGCAAGAATTGCTAGAGGAAACGTTGTAGACCCAAAGGATATT
TCCCCTAATGATTTTGATATGCTAATTTTGCCTGGTGGATTTGGAGTTGCTAAAAATTATTCCGATATTTTGAAAGGTGA
AAGTCCCGTAAGTGTGTTAGAGGAAGTAAAGCAGACAATCGTAAAGTTTCATAAGGAAAAGAAGGCCATCGGAGCTATAT
GTATTGCTCCTGCTATCGTTGCTGCTTCTCTTAGTAGTGTGTCAAAGGTAAAAGTGACACTTGGAGAAGACATAGATTCT
ATAATATCAAGGTGCGGCGGAGAGCATGTTTTTTGCGAAACGGACGATTATGTAGCTGATATTGATATGGGTGTTTTTTC
CACTCCAGCATATATGCGTAAGGACAGCTTACACAAAATTCACGTTGGAATACATAAAATGGTCGGAGCTATGGTGGATT
TTGTTAAAAAGAAAGAGCAACTTTAG

Upstream 100 bases:

>100_bases
GTAAGCAGACTAAGCACTCATGACGTAAGGTCTTGTTTTGGTTATATGGAACATGGTTTGTGATATTATGTATCACTGTT
AGCATTTTTTATGAGGAGTT

Downstream 100 bases:

>100_bases
AACAATACTTAATATAGTGTGCATAAAACATTGCGCGCGTGTTTTATGCACATACGAAGTTGTTTGCATGTGTAGTTCGT
AGTTTCAATATCCTACTGAT

Product: isoprenoid biosynthesis protein with amidotransferase-like domain

Products: NA

Alternate protein names: Sigma cross-reacting protein 27A; SCRP-27A [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNCAVLLCGCGHMDGSEIREAVLALLALDSYGINVTCCAPNIKQVDVVDHLSGSTLEEERDIMSESARIARGNVVDPKDI
SPNDFDMLILPGGFGVAKNYSDILKGESPVSVLEEVKQTIVKFHKEKKAIGAICIAPAIVAASLSSVSKVKVTLGEDIDS
IISRCGGEHVFCETDDYVADIDMGVFSTPAYMRKDSLHKIHVGIHKMVGAMVDFVKKKEQL

Sequences:

>Translated_221_residues
MNCAVLLCGCGHMDGSEIREAVLALLALDSYGINVTCCAPNIKQVDVVDHLSGSTLEEERDIMSESARIARGNVVDPKDI
SPNDFDMLILPGGFGVAKNYSDILKGESPVSVLEEVKQTIVKFHKEKKAIGAICIAPAIVAASLSSVSKVKVTLGEDIDS
IISRCGGEHVFCETDDYVADIDMGVFSTPAYMRKDSLHKIHVGIHKMVGAMVDFVKKKEQL
>Mature_221_residues
MNCAVLLCGCGHMDGSEIREAVLALLALDSYGINVTCCAPNIKQVDVVDHLSGSTLEEERDIMSESARIARGNVVDPKDI
SPNDFDMLILPGGFGVAKNYSDILKGESPVSVLEEVKQTIVKFHKEKKAIGAICIAPAIVAASLSSVSKVKVTLGEDIDS
IISRCGGEHVFCETDDYVADIDMGVFSTPAYMRKDSLHKIHVGIHKMVGAMVDFVKKKEQL

Specific function: May be involved in the early steps of isoprenoid biosynthesis [H]

COG id: COG3155

COG function: function code Q; Uncharacterized protein involved in an early stage of isoprenoid biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ES1 family [H]

Homologues:

Organism=Homo sapiens, GI296531406, Length=226, Percent_Identity=36.7256637168142, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI296531408, Length=226, Percent_Identity=32.7433628318584, Blast_Score=104, Evalue=6e-23,
Organism=Escherichia coli, GI87082228, Length=206, Percent_Identity=40.7766990291262, Blast_Score=156, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 23825; Mature: 23825

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCAVLLCGCGHMDGSEIREAVLALLALDSYGINVTCCAPNIKQVDVVDHLSGSTLEEER
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEHHHHHCCCCCHHHHH
DIMSESARIARGNVVDPKDISPNDFDMLILPGGFGVAKNYSDILKGESPVSVLEEVKQTI
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
VKFHKEKKAIGAICIAPAIVAASLSSVSKVKVTLGEDIDSIISRCGGEHVFCETDDYVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCEEEECCCCEEEE
IDMGVFSTPAYMRKDSLHKIHVGIHKMVGAMVDFVKKKEQL
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNCAVLLCGCGHMDGSEIREAVLALLALDSYGINVTCCAPNIKQVDVVDHLSGSTLEEER
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEHHHHHCCCCCHHHHH
DIMSESARIARGNVVDPKDISPNDFDMLILPGGFGVAKNYSDILKGESPVSVLEEVKQTI
HHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
VKFHKEKKAIGAICIAPAIVAASLSSVSKVKVTLGEDIDSIISRCGGEHVFCETDDYVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHCCCCEEEECCCCEEEE
IDMGVFSTPAYMRKDSLHKIHVGIHKMVGAMVDFVKKKEQL
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 1575737; 9603997 [H]