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The map label for this gene is visC [C]

Identifier: 88606947

GI number: 88606947

Start: 9321

End: 10499

Strand: Direct

Name: visC [C]

Synonym: APH_0009

Alternate gene names: 88606947

Gene position: 9321-10499 (Clockwise)

Preceding gene: 88606844

Following gene: 88607115

Centisome position: 0.63

GC content: 35.37

Gene sequence:

>1179_bases
TTGGTTGATATAGTGTCTAATTACTACGATGTTGTAATTCTCGGTGGTGGGATAAACGGTGTTTTGTGTGCGATAGGTTT
ATCGCATAAAGATATATCAGTGTTAGTAGTTGAAGAAAGGGACGCAATACTTGATGGTAATCAAGGTAGGGTGTACGCCT
TTTCAAAACGCTCAAAAGAAATACTAGAAAATTTTTCTGTATGGAATGATGAAATCAGATCATCTCCTATAGATCATATA
ATGATTTATGATGGAAATAGCTGCTCCTCTGTGCATTATGATCGTGTCTTGGTTGATGATCAACCTATGGGGTACGTGGT
TGAGGCAAGCGAGATCGCAAAATTCATGCACCAAAAGCTAAATTTCGATGTTATTACATCCTCTTCCTGCAAGTTATTTA
CAGTTAAAGACGGATTTGCAGAAATATATCTGTCCTGTGGAAAAAAAATCTATACTAAACTTGTAGTGTGTGCCGAAGGA
AAAAATTCTAGGTTTAGAAATAGCTTATCTCTAAAGACTATAAACTACGCTTTTGAACAGGGATTCATAGTTTGTAACAT
AAACCACTCAAAACATCATAGAAACACGGCTATAGAGCATTTTTGTACAAATGGACCTTTTGCTATTCTCCCAATGTATG
GAGGTTATTCCTCTTCCATAGTTTGGACTGAAAAATATGAAATGGCACAACTAATACAAAATCTACCTATAGAAGAGTTT
ACAAAACTACTACAGGAAAAATGCAGCGATTTCCTAGGCAAAATAGAGGTAAACAGCAAAATAAATTGCTATAAAACCTC
AATGTCGCTCCTAAAAAAAATATTTATAAATAGAGCCATAATCATTGGTGATGCAGCTCATGCAATACATCCAGTAGCTG
GTCAGGGATTGAACCTAGGTATAAGAGATGTTGGTATTTTGGTAGAAATAATAGAAAAATACCACAAATTAGGTTCGGAT
ATAGGGCAGAGGTTTATATTACAGGAAATAGATAACAGAAGGCTGTTAGATAATGTTTCTATGTCATTTGTGTGCACTGG
AATAAATTCGATATTCTCAAATGATTCTGCGATTTTAAAAGTCGCTAGAAGAGCAACAATGTCTGTGGTTGAAATGTCGC
CCACACTAAAAAAAATTCTTATGAGCCATGCTATGGGCATTAGCTCAATCTGTAAGTAG

Upstream 100 bases:

>100_bases
TCTCAGTATGTTGTGTCCGTAGCTCAGCTGGATAGAGCAACAGCCTTCTAAGCTGTGGGTCAGGGGTTCGAATCCCTTCG
GGCACACCATGCACTGAGTA

Downstream 100 bases:

>100_bases
GTGTGTATATTTAAGTTGAGTACTTTTTATTCAAATAAACACGTAATGGATTTTATACCATTAACAAATAACGAAAGCTG
AATTCTTTTTGTCTTTTCCT

Product: UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MVDIVSNYYDVVILGGGINGVLCAIGLSHKDISVLVVEERDAILDGNQGRVYAFSKRSKEILENFSVWNDEIRSSPIDHI
MIYDGNSCSSVHYDRVLVDDQPMGYVVEASEIAKFMHQKLNFDVITSSSCKLFTVKDGFAEIYLSCGKKIYTKLVVCAEG
KNSRFRNSLSLKTINYAFEQGFIVCNINHSKHHRNTAIEHFCTNGPFAILPMYGGYSSSIVWTEKYEMAQLIQNLPIEEF
TKLLQEKCSDFLGKIEVNSKINCYKTSMSLLKKIFINRAIIIGDAAHAIHPVAGQGLNLGIRDVGILVEIIEKYHKLGSD
IGQRFILQEIDNRRLLDNVSMSFVCTGINSIFSNDSAILKVARRATMSVVEMSPTLKKILMSHAMGISSICK

Sequences:

>Translated_392_residues
MVDIVSNYYDVVILGGGINGVLCAIGLSHKDISVLVVEERDAILDGNQGRVYAFSKRSKEILENFSVWNDEIRSSPIDHI
MIYDGNSCSSVHYDRVLVDDQPMGYVVEASEIAKFMHQKLNFDVITSSSCKLFTVKDGFAEIYLSCGKKIYTKLVVCAEG
KNSRFRNSLSLKTINYAFEQGFIVCNINHSKHHRNTAIEHFCTNGPFAILPMYGGYSSSIVWTEKYEMAQLIQNLPIEEF
TKLLQEKCSDFLGKIEVNSKINCYKTSMSLLKKIFINRAIIIGDAAHAIHPVAGQGLNLGIRDVGILVEIIEKYHKLGSD
IGQRFILQEIDNRRLLDNVSMSFVCTGINSIFSNDSAILKVARRATMSVVEMSPTLKKILMSHAMGISSICK
>Mature_392_residues
MVDIVSNYYDVVILGGGINGVLCAIGLSHKDISVLVVEERDAILDGNQGRVYAFSKRSKEILENFSVWNDEIRSSPIDHI
MIYDGNSCSSVHYDRVLVDDQPMGYVVEASEIAKFMHQKLNFDVITSSSCKLFTVKDGFAEIYLSCGKKIYTKLVVCAEG
KNSRFRNSLSLKTINYAFEQGFIVCNINHSKHHRNTAIEHFCTNGPFAILPMYGGYSSSIVWTEKYEMAQLIQNLPIEEF
TKLLQEKCSDFLGKIEVNSKINCYKTSMSLLKKIFINRAIIIGDAAHAIHPVAGQGLNLGIRDVGILVEIIEKYHKLGSD
IGQRFILQEIDNRRLLDNVSMSFVCTGINSIFSNDSAILKVARRATMSVVEMSPTLKKILMSHAMGISSICK

Specific function: Not Yet Known. [C]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=386, Percent_Identity=22.7979274611399, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789273, Length=398, Percent_Identity=29.3969849246231, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1789274, Length=387, Percent_Identity=25.8397932816537, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786883, Length=388, Percent_Identity=24.7422680412371, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25146631, Length=437, Percent_Identity=27.2311212814645, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI19920760, Length=384, Percent_Identity=22.1354166666667, Blast_Score=104, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 43822; Mature: 43822

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDIVSNYYDVVILGGGINGVLCAIGLSHKDISVLVVEERDAILDGNQGRVYAFSKRSKE
CCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCEEECCCCCEEEECHHHHH
ILENFSVWNDEIRSSPIDHIMIYDGNSCSSVHYDRVLVDDQPMGYVVEASEIAKFMHQKL
HHHHHHHCCHHHHCCCCCEEEEEECCCCCCEEECEEEECCCCCCEEEEHHHHHHHHHHHC
NFDVITSSSCKLFTVKDGFAEIYLSCGKKIYTKLVVCAEGKNSRFRNSLSLKTINYAFEQ
CEEEEECCCEEEEEECCCHHHHHHHHCHHHHEEEEEEECCCCCHHHCCCEEEEEEEHHHC
GFIVCNINHSKHHRNTAIEHFCTNGPFAILPMYGGYSSSIVWTEKYEMAQLIQNLPIEEF
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECHHHHHHHHHCCCHHHH
TKLLQEKCSDFLGKIEVNSKINCYKTSMSLLKKIFINRAIIIGDAAHAIHPVAGQGLNLG
HHHHHHHHHHHHCEEEECCCCEEHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCCCCC
IRDVGILVEIIEKYHKLGSDIGQRFILQEIDNRRLLDNVSMSFVCTGINSIFSNDSAILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECHHHHHCCCHHHHH
VARRATMSVVEMSPTLKKILMSHAMGISSICK
HHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure
MVDIVSNYYDVVILGGGINGVLCAIGLSHKDISVLVVEERDAILDGNQGRVYAFSKRSKE
CCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCEEECCCCCEEEECHHHHH
ILENFSVWNDEIRSSPIDHIMIYDGNSCSSVHYDRVLVDDQPMGYVVEASEIAKFMHQKL
HHHHHHHCCHHHHCCCCCEEEEEECCCCCCEEECEEEECCCCCCEEEEHHHHHHHHHHHC
NFDVITSSSCKLFTVKDGFAEIYLSCGKKIYTKLVVCAEGKNSRFRNSLSLKTINYAFEQ
CEEEEECCCEEEEEECCCHHHHHHHHCHHHHEEEEEEECCCCCHHHCCCEEEEEEEHHHC
GFIVCNINHSKHHRNTAIEHFCTNGPFAILPMYGGYSSSIVWTEKYEMAQLIQNLPIEEF
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEECHHHHHHHHHCCCHHHH
TKLLQEKCSDFLGKIEVNSKINCYKTSMSLLKKIFINRAIIIGDAAHAIHPVAGQGLNLG
HHHHHHHHHHHHCEEEECCCCEEHHHHHHHHHHHHHCCEEEEECCHHHHCCCCCCCCCCC
IRDVGILVEIIEKYHKLGSDIGQRFILQEIDNRRLLDNVSMSFVCTGINSIFSNDSAILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECHHHHHCCCHHHHH
VARRATMSVVEMSPTLKKILMSHAMGISSICK
HHHHHHHHHHHCCHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]