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The map label for this gene is fusA [H]

Identifier: 88606769

GI number: 88606769

Start: 470781

End: 471008

Strand: Reverse

Name: fusA [H]

Synonym: APH_0448

Alternate gene names: 88606769

Gene position: 471008-470781 (Counterclockwise)

Preceding gene: 88607610

Following gene: 88606708

Centisome position: 32.01

GC content: 38.6

Gene sequence:

>228_bases
ATGCAGGATTACATCTACTCTGTTGTGTTGAATTCCGGTAAGGGTTATACAGAGTCTGTAGGTAGGATTTTGTTAATGCA
CGAGAATAACAGGGAAGACATAAGGGAGATAAAGGCCGGTGATATTGCGGCGCTAGCTGGGCTTAAGAAGACTACTACTC
AGAAGATAAAACAGAACTTGATATCCTGTAATTCAACTGTGATTACTTATATCAAACAACAAAATTAG

Upstream 100 bases:

>100_bases
GCACTCCCGTAAGGATAGATAAAAACCTACCTACTTACACAAAAACACAGTGTCCATATCCCCTGCATAATACGATAATT
TAAAGGAAACTAATCTCTAG

Downstream 100 bases:

>100_bases
TCATTCAACACTGCAAGCGCATCACTAATACGCAAAAAATTCTCAAACTCTACATCTAATTTAAAATGCAACCTAGGCAC
ATACCTGAGTTTGAGATACT

Product: translation elongation factor G, truncation

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MQDYIYSVVLNSGKGYTESVGRILLMHENNREDIREIKAGDIAALAGLKKTTTQKIKQNLISCNSTVITYIKQQN

Sequences:

>Translated_75_residues
MQDYIYSVVLNSGKGYTESVGRILLMHENNREDIREIKAGDIAALAGLKKTTTQKIKQNLISCNSTVITYIKQQN
>Mature_75_residues
MQDYIYSVVLNSGKGYTESVGRILLMHENNREDIREIKAGDIAALAGLKKTTTQKIKQNLISCNSTVITYIKQQN

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 8432; Mature: 8432

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDYIYSVVLNSGKGYTESVGRILLMHENNREDIREIKAGDIAALAGLKKTTTQKIKQNL
CCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
ISCNSTVITYIKQQN
HCCCCCEEEEEECCC
>Mature Secondary Structure
MQDYIYSVVLNSGKGYTESVGRILLMHENNREDIREIKAGDIAALAGLKKTTTQKIKQNL
CCCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCHHHHHCCCHHHHHHHHHHH
ISCNSTVITYIKQQN
HCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA