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The map label for this gene is ribE [H]

Identifier: 87200871

GI number: 87200871

Start: 3081734

End: 3082357

Strand: Direct

Name: ribE [H]

Synonym: Saro_2858

Alternate gene names: 87200871

Gene position: 3081734-3082357 (Clockwise)

Preceding gene: 87200870

Following gene: 87200875

Centisome position: 86.53

GC content: 64.58

Gene sequence:

>624_bases
ATGTTCACCGGGATCGTCACCGAAGTCGGCAATATCCTCGCCATCGAGGACAAGGGCGACCGCCACGTCACGATTTCCTG
CGCGATGGACCCGGCGAAGATCGCCATCGGCGCCTCCATCGCATGTTCGGGCGTGTGCCTGACTGTGGTGGACAAGGGCG
GCGTGGCCGGCGAAGGCTGGTTCGCGGTGGACGTCTCGGGCGAGACGGTGAGCCGCACCGCGCCGGAACAGTGGACGGTG
GGCGCGCCTCTGAACCTCGAACCCGCGCTGAAGCTCGGCGATGAACTGGGCGGCCACATCGTGACCGGCCATGTCGACGC
GGTGGGCGAAGTGGTGGGGGTGTGTCCGGAAGGCGCATCGCTGAAATTCGGCATTTCCGCACCGAAGGAACTTGCACCCT
ATATCGCGGCCAAGGGATCGATCACGGTCAACGGCGTTTCGCTGACGGTGAACGAGGTTGCGGATCAGCCTGACGGATCG
TGCCACTTCGCGCTGAACATCATTCCCCACACCGCGCAGGTGACGACGCTTGGCACGCTGGCGCCGGGGCACAAGGTCAA
TCTCGAGATCGACGTGCTGGCACGCTATCTCAAGCGTATGCAGAGCCTGGCTGCGCAGGGGTGA

Upstream 100 bases:

>100_bases
GCTCGGCGAGGCGCACGGGCGGTGGCGCAATGTGGACCGGCGGACGCTTGGCAGCGACAACCTCGACGTATACGAGCGCA
TCGGTTGAAGGAGATTTGAG

Downstream 100 bases:

>100_bases
ACGCAAGCTCCCGTTCGTGTCTCGACTTCGCTCGACACGAACGGAGACGGGGTCTAATCAGGCGCAGCCCAGCACGATCC
GGAGCAATTGTTCGGGCTGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFTGIVTEVGNILAIEDKGDRHVTISCAMDPAKIAIGASIACSGVCLTVVDKGGVAGEGWFAVDVSGETVSRTAPEQWTV
GAPLNLEPALKLGDELGGHIVTGHVDAVGEVVGVCPEGASLKFGISAPKELAPYIAAKGSITVNGVSLTVNEVADQPDGS
CHFALNIIPHTAQVTTLGTLAPGHKVNLEIDVLARYLKRMQSLAAQG

Sequences:

>Translated_207_residues
MFTGIVTEVGNILAIEDKGDRHVTISCAMDPAKIAIGASIACSGVCLTVVDKGGVAGEGWFAVDVSGETVSRTAPEQWTV
GAPLNLEPALKLGDELGGHIVTGHVDAVGEVVGVCPEGASLKFGISAPKELAPYIAAKGSITVNGVSLTVNEVADQPDGS
CHFALNIIPHTAQVTTLGTLAPGHKVNLEIDVLARYLKRMQSLAAQG
>Mature_207_residues
MFTGIVTEVGNILAIEDKGDRHVTISCAMDPAKIAIGASIACSGVCLTVVDKGGVAGEGWFAVDVSGETVSRTAPEQWTV
GAPLNLEPALKLGDELGGHIVTGHVDAVGEVVGVCPEGASLKFGISAPKELAPYIAAKGSITVNGVSLTVNEVADQPDGS
CHFALNIIPHTAQVTTLGTLAPGHKVNLEIDVLARYLKRMQSLAAQG

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=194, Percent_Identity=33.5051546391753, Blast_Score=95, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319733, Length=208, Percent_Identity=33.6538461538462, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21205; Mature: 21205

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTEVGNILAIEDKGDRHVTISCAMDPAKIAIGASIACSGVCLTVVDKGGVAGEGW
CCCCEEECCCCEEEEECCCCEEEEEEEECCCCEEEECCCEEECCEEEEEEECCCCCCCCE
FAVDVSGETVSRTAPEQWTVGAPLNLEPALKLGDELGGHIVTGHVDAVGEVVGVCPEGAS
EEEEECCCEECCCCCCCEECCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHEEECCCCCC
LKFGISAPKELAPYIAAKGSITVNGVSLTVNEVADQPDGSCHFALNIIPHTAQVTTLGTL
EEECCCCCHHHHHHHCCCCCEEEEEEEEEEEHHCCCCCCCEEEEEEEECCCEEEEEEEEC
APGHKVNLEIDVLARYLKRMQSLAAQG
CCCCEEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIVTEVGNILAIEDKGDRHVTISCAMDPAKIAIGASIACSGVCLTVVDKGGVAGEGW
CCCCEEECCCCEEEEECCCCEEEEEEEECCCCEEEECCCEEECCEEEEEEECCCCCCCCE
FAVDVSGETVSRTAPEQWTVGAPLNLEPALKLGDELGGHIVTGHVDAVGEVVGVCPEGAS
EEEEECCCEECCCCCCCEECCCCCCCCHHHHHHHHCCCEEEECCHHHHHHHEEECCCCCC
LKFGISAPKELAPYIAAKGSITVNGVSLTVNEVADQPDGSCHFALNIIPHTAQVTTLGTL
EEECCCCCHHHHHHHCCCCCEEEEEEEEEEEHHCCCCCCCEEEEEEEECCCEEEEEEEEC
APGHKVNLEIDVLARYLKRMQSLAAQG
CCCCEEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]