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The map label for this gene is ribD [H]

Identifier: 87200870

GI number: 87200870

Start: 3080750

End: 3081721

Strand: Direct

Name: ribD [H]

Synonym: Saro_2857

Alternate gene names: 87200870

Gene position: 3080750-3081721 (Clockwise)

Preceding gene: 87200869

Following gene: 87200871

Centisome position: 86.5

GC content: 72.12

Gene sequence:

>972_bases
ATGAGCGCCGCCGACGACCTGCGCTGGCTTGACGCGGCAGCTAGCCTCGGCGCGCGCGGGCGACCTCTCAGCAGGCCCAA
TCCGGCGGTCGGCGCGGTAATCGTCAATGACGGCGTGGTCGTTGGCCGTGGGTGGACGCAGGCCGGCGGACGGCCCCATG
CGGAGGCCGGTGCGCTGATGGCGGCGGGCGACGCGGCGCAAGGGGCAACGCTCTACGTGACGCTGGAACCCTGTGCCCAC
GCCAGCGAACGCGGGCCGTCGTGCACCTCGCTGGTGCTGAAGAGCGGGCTTGCGCGGGTGGTGATCGGCATCGAGGACCC
CGATCCTCGCACGGCGGGTGGCGGAATTGCGGCGCTGCGCAGCGCGGGCATCGCGGCCGATGTGGTGCCGTCGGCAGCGG
CGCGCGCTTCGCTGGTGGGTTATCTCGTGCGCACGGCAACGGGGCGGCCGCACGTCACGCTCAAGCTTGCGACCTCGCTC
GACGGGCGCATCGCGCTGGCCGATGGCACGAGCAAGTGGATCACCGGGCCGGAAGCGCGGGCGCACTGTCATGTCGAGCG
GGCGCGGGCGGACGCGATCCTCGTGGGCGGCGGCACCTTGCGCGCCGACGCGCCCCGGCTGGACGTGCGCCTGCCCGGGC
TGGAAGCGCGCAGTCCGAAGCGAATGGTGCTGACGCGGGGCATCGCACCGGATGGCTGGACGGGGGTGGCGGACATTGCC
GCAACGGGGGCGTTCGGAGACGCGCAGTACCTGTTCGTCGAAGGCGGAGCGGGTGCGGCGGCGGCATTCCTGGCCGCAGA
CATGGTCGACCGCCTGCTGATTTACCGCGCGCCGGTCGTCATCGGCCAGGGATTGCCCTGCATCGGCGACATTGGCCTGG
GATCGCTCGGCGAGGCGCACGGGCGGTGGCGCAATGTGGACCGGCGGACGCTTGGCAGCGACAACCTCGACGTATACGAG
CGCATCGGTTGA

Upstream 100 bases:

>100_bases
AGCGCAAGCTCGACGCGGCGCGCAAGGCGATCCTCGACAAGCACATGATCGATAATCCGGTGTTCGACGAGGCGACCGGC
AAGGAACAGCCCGGAACGCA

Downstream 100 bases:

>100_bases
AGGAGATTTGAGATGTTCACCGGGATCGTCACCGAAGTCGGCAATATCCTCGCCATCGAGGACAAGGGCGACCGCCACGT
CACGATTTCCTGCGCGATGG

Product: diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSAADDLRWLDAAASLGARGRPLSRPNPAVGAVIVNDGVVVGRGWTQAGGRPHAEAGALMAAGDAAQGATLYVTLEPCAH
ASERGPSCTSLVLKSGLARVVIGIEDPDPRTAGGGIAALRSAGIAADVVPSAAARASLVGYLVRTATGRPHVTLKLATSL
DGRIALADGTSKWITGPEARAHCHVERARADAILVGGGTLRADAPRLDVRLPGLEARSPKRMVLTRGIAPDGWTGVADIA
ATGAFGDAQYLFVEGGAGAAAAFLAADMVDRLLIYRAPVVIGQGLPCIGDIGLGSLGEAHGRWRNVDRRTLGSDNLDVYE
RIG

Sequences:

>Translated_323_residues
MSAADDLRWLDAAASLGARGRPLSRPNPAVGAVIVNDGVVVGRGWTQAGGRPHAEAGALMAAGDAAQGATLYVTLEPCAH
ASERGPSCTSLVLKSGLARVVIGIEDPDPRTAGGGIAALRSAGIAADVVPSAAARASLVGYLVRTATGRPHVTLKLATSL
DGRIALADGTSKWITGPEARAHCHVERARADAILVGGGTLRADAPRLDVRLPGLEARSPKRMVLTRGIAPDGWTGVADIA
ATGAFGDAQYLFVEGGAGAAAAFLAADMVDRLLIYRAPVVIGQGLPCIGDIGLGSLGEAHGRWRNVDRRTLGSDNLDVYE
RIG
>Mature_322_residues
SAADDLRWLDAAASLGARGRPLSRPNPAVGAVIVNDGVVVGRGWTQAGGRPHAEAGALMAAGDAAQGATLYVTLEPCAHA
SERGPSCTSLVLKSGLARVVIGIEDPDPRTAGGGIAALRSAGIAADVVPSAAARASLVGYLVRTATGRPHVTLKLATSLD
GRIALADGTSKWITGPEARAHCHVERARADAILVGGGTLRADAPRLDVRLPGLEARSPKRMVLTRGIAPDGWTGVADIAA
TGAFGDAQYLFVEGGAGAAAAFLAADMVDRLLIYRAPVVIGQGLPCIGDIGLGSLGEAHGRWRNVDRRTLGSDNLDVYER
IG

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=328, Percent_Identity=37.1951219512195, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 32990; Mature: 32859

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAADDLRWLDAAASLGARGRPLSRPNPAVGAVIVNDGVVVGRGWTQAGGRPHAEAGALM
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCCEE
AAGDAAQGATLYVTLEPCAHASERGPSCTSLVLKSGLARVVIGIEDPDPRTAGGGIAALR
EECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHH
SAGIAADVVPSAAARASLVGYLVRTATGRPHVTLKLATSLDGRIALADGTSKWITGPEAR
HCCCHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCH
AHCHVERARADAILVGGGTLRADAPRLDVRLPGLEARSPKRMVLTRGIAPDGWTGVADIA
HEEEEEECCCCEEEECCCEEECCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHH
ATGAFGDAQYLFVEGGAGAAAAFLAADMVDRLLIYRAPVVIGQGLPCIGDIGLGSLGEAH
HCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEECCCCCCCCHHC
GRWRNVDRRTLGSDNLDVYERIG
CHHCCCCHHHCCCCCCHHHHHCC
>Mature Secondary Structure 
SAADDLRWLDAAASLGARGRPLSRPNPAVGAVIVNDGVVVGRGWTQAGGRPHAEAGALM
CCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCCCCCCEE
AAGDAAQGATLYVTLEPCAHASERGPSCTSLVLKSGLARVVIGIEDPDPRTAGGGIAALR
EECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHH
SAGIAADVVPSAAARASLVGYLVRTATGRPHVTLKLATSLDGRIALADGTSKWITGPEAR
HCCCHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCCCH
AHCHVERARADAILVGGGTLRADAPRLDVRLPGLEARSPKRMVLTRGIAPDGWTGVADIA
HEEEEEECCCCEEEECCCEEECCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHH
ATGAFGDAQYLFVEGGAGAAAAFLAADMVDRLLIYRAPVVIGQGLPCIGDIGLGSLGEAH
HCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCCEECCCCCCCCHHC
GRWRNVDRRTLGSDNLDVYERIG
CHHCCCCHHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]