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The map label for this gene is garD [H]

Identifier: 87200443

GI number: 87200443

Start: 2613829

End: 2615037

Strand: Reverse

Name: garD [H]

Synonym: Saro_2430

Alternate gene names: 87200443

Gene position: 2615037-2613829 (Counterclockwise)

Preceding gene: 87200444

Following gene: 87200442

Centisome position: 73.42

GC content: 67.91

Gene sequence:

>1209_bases
ATGAGCGCCCCCTCCTTCGAGGGATACCTGCGCGTCGATGGCCGCAAGGGCATCCGCAACGTCATCCTCGTCGCCTATCT
GGTCGAGTGCGCACACCACGTTGCCCGCCGCATCGTCTCGGCGGCGGACGAGCCTTCGGTGCAACTAGCCGGATTTCCCG
GCTGCTATCCCAATGCCTACGCAGCGCAGATGATGGAGGCTATCGCCACGCATCCAAACGTAGGCGGGGTACTGGTCGTC
TCGCTCGGCTGCGAAGGCTTCGACCGGAGCGCGCTGGCCGAGGCGGTCGCGGCCAGCGGGCGTCCCGTCGAGACGCTGGT
CATCCAGCAGGCCGGCGGCACGCGCGCCACCATCGCGGCGGGCCTTGCCGCGGTGGAGCGCATCCGCGCCGCCGCCGCCG
CTGCTCCTCGCGTGCCGATGGGCGTGGCCGACCTCGTCGTCGGCACGATCTGTGGCGGGTCCGACGGCACAAGCGGCATC
ACCGCCAACCCGGCCGTGGGCCGCTGCTTCGATACGCTCGTCGCCGCTGGTGCCACCTGCATCTTCGAGGAGACGGGCGA
ACTTATCGGCTGCGAGCAGGTCATGGCGGGCCGCGCCGTCACCGCCGCGCTTGGCCGCGAGATCGAGGAATGCGTGGCCA
AGGCCGCGCGCTACTATGCCACGCTCGGCTATGGCAGCTTTGCTCCCGGCAATGCCGACGGCGGCCTGACGACGCAGGAA
GAGAAGTCGCTTGGCGCATATTCGAAGTCGGGTGCCTCGTCCATCTCCGGCCTGATCCGTCCGGGCGAGCGGCCATCCGG
CCCGGGCCTTTACCTCATGGACGTCGTGCCCGACGGTGAAGTGCGCTTCGGCTTTCCCAACATCTCCGACAATGCCGAGA
TCGTCGAGATGATCGCGTCGGGTTGCCATGTGATCCTGTTCACCACCGGGCGCGGTTCGGTGGTCGGCTCGGCGGTGTCG
CCGGTCATCAAGGTCTGCGCAAACCCCGAGACCTATGCGCGTCTGGCCGACGACATGGACGTTGATGCCGGGCGCATCCT
GCTCGGCAAGGCCACCCTCGACGAGGTCGGCGCAGAGATCCTCGACCAGGTGATCCGCGTTGCGTCGGGTGGCGAAAGCC
TGTCCGAGGCGCTCGGCCATCAGGAATTCATCCTCACCTACAAGCAGTTCGAGCCCAGCGGTCCGGCCTGCCAGCCTGCC
ATTGCCTGA

Upstream 100 bases:

>100_bases
CCGCTGACGCCGCGATTGCCGAGCACGTCCACTCTCACAATCTCGGAAGCGATTACATCGCCGCCCACGGTCGCGGCGGC
CAGGCCGGGGGAACGCGGGA

Downstream 100 bases:

>100_bases
CGGAGCGACCATGACGACCACTTTCGACCTTTCAGGCAAGCGCGCGCTGGTTACCGGCGCCGGGCAGGGCATCGGCCGGG
CCAGCGCCGAGGCGTTCCGC

Product: Altronate dehydratase

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSAPSFEGYLRVDGRKGIRNVILVAYLVECAHHVARRIVSAADEPSVQLAGFPGCYPNAYAAQMMEAIATHPNVGGVLVV
SLGCEGFDRSALAEAVAASGRPVETLVIQQAGGTRATIAAGLAAVERIRAAAAAAPRVPMGVADLVVGTICGGSDGTSGI
TANPAVGRCFDTLVAAGATCIFEETGELIGCEQVMAGRAVTAALGREIEECVAKAARYYATLGYGSFAPGNADGGLTTQE
EKSLGAYSKSGASSISGLIRPGERPSGPGLYLMDVVPDGEVRFGFPNISDNAEIVEMIASGCHVILFTTGRGSVVGSAVS
PVIKVCANPETYARLADDMDVDAGRILLGKATLDEVGAEILDQVIRVASGGESLSEALGHQEFILTYKQFEPSGPACQPA
IA

Sequences:

>Translated_402_residues
MSAPSFEGYLRVDGRKGIRNVILVAYLVECAHHVARRIVSAADEPSVQLAGFPGCYPNAYAAQMMEAIATHPNVGGVLVV
SLGCEGFDRSALAEAVAASGRPVETLVIQQAGGTRATIAAGLAAVERIRAAAAAAPRVPMGVADLVVGTICGGSDGTSGI
TANPAVGRCFDTLVAAGATCIFEETGELIGCEQVMAGRAVTAALGREIEECVAKAARYYATLGYGSFAPGNADGGLTTQE
EKSLGAYSKSGASSISGLIRPGERPSGPGLYLMDVVPDGEVRFGFPNISDNAEIVEMIASGCHVILFTTGRGSVVGSAVS
PVIKVCANPETYARLADDMDVDAGRILLGKATLDEVGAEILDQVIRVASGGESLSEALGHQEFILTYKQFEPSGPACQPA
IA
>Mature_401_residues
SAPSFEGYLRVDGRKGIRNVILVAYLVECAHHVARRIVSAADEPSVQLAGFPGCYPNAYAAQMMEAIATHPNVGGVLVVS
LGCEGFDRSALAEAVAASGRPVETLVIQQAGGTRATIAAGLAAVERIRAAAAAAPRVPMGVADLVVGTICGGSDGTSGIT
ANPAVGRCFDTLVAAGATCIFEETGELIGCEQVMAGRAVTAALGREIEECVAKAARYYATLGYGSFAPGNADGGLTTQEE
KSLGAYSKSGASSISGLIRPGERPSGPGLYLMDVVPDGEVRFGFPNISDNAEIVEMIASGCHVILFTTGRGSVVGSAVSP
VIKVCANPETYARLADDMDVDAGRILLGKATLDEVGAEILDQVIRVASGGESLSEALGHQEFILTYKQFEPSGPACQPAI
A

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=392, Percent_Identity=30.3571428571429, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1789516, Length=407, Percent_Identity=32.4324324324324, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 41196; Mature: 41065

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPSFEGYLRVDGRKGIRNVILVAYLVECAHHVARRIVSAADEPSVQLAGFPGCYPNAY
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHH
AAQMMEAIATHPNVGGVLVVSLGCEGFDRSALAEAVAASGRPVETLVIQQAGGTRATIAA
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
GLAAVERIRAAAAAAPRVPMGVADLVVGTICGGSDGTSGITANPAVGRCFDTLVAAGATC
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
IFEETGELIGCEQVMAGRAVTAALGREIEECVAKAARYYATLGYGSFAPGNADGGLTTQE
EEHHCCCHHCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
EKSLGAYSKSGASSISGLIRPGERPSGPGLYLMDVVPDGEVRFGFPNISDNAEIVEMIAS
HHHCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHC
GCHVILFTTGRGSVVGSAVSPVIKVCANPETYARLADDMDVDAGRILLGKATLDEVGAEI
CCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHH
LDQVIRVASGGESLSEALGHQEFILTYKQFEPSGPACQPAIA
HHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPSFEGYLRVDGRKGIRNVILVAYLVECAHHVARRIVSAADEPSVQLAGFPGCYPNAY
CCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHH
AAQMMEAIATHPNVGGVLVVSLGCEGFDRSALAEAVAASGRPVETLVIQQAGGTRATIAA
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
GLAAVERIRAAAAAAPRVPMGVADLVVGTICGGSDGTSGITANPAVGRCFDTLVAAGATC
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCE
IFEETGELIGCEQVMAGRAVTAALGREIEECVAKAARYYATLGYGSFAPGNADGGLTTQE
EEHHCCCHHCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
EKSLGAYSKSGASSISGLIRPGERPSGPGLYLMDVVPDGEVRFGFPNISDNAEIVEMIAS
HHHCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHC
GCHVILFTTGRGSVVGSAVSPVIKVCANPETYARLADDMDVDAGRILLGKATLDEVGAEI
CCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEECCHHHHHHHHH
LDQVIRVASGGESLSEALGHQEFILTYKQFEPSGPACQPAIA
HHHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]