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The map label for this gene is aroB

Identifier: 87199916

GI number: 87199916

Start: 2011490

End: 2012599

Strand: Reverse

Name: aroB

Synonym: Saro_1899

Alternate gene names: 87199916

Gene position: 2012599-2011490 (Counterclockwise)

Preceding gene: 87199917

Following gene: 87199904

Centisome position: 56.51

GC content: 66.31

Gene sequence:

>1110_bases
ATGGCTGTAATCCCCGTCGCCATCGCCGGAGCGCCCTATGAAGTGCGGATCGAGGCCGGCGTTCTGGCCCGTGCGGGCGA
ACATTGCCGCCCCTTTCTGCGCAAGGACCGCGTGGCTATCGTCACCGACGAGCACGTCGCCGCAGAGTGGCGGGAAACCG
TCACTGCCTCGTTCGACAGCGTCGGCGTGCGCAGCGAATGGCTCGTTCTCCCCGCTGGCGAGAGCACCAAGAGCTGGGAA
CACCTCGCCCGCCTGGTCGACTGGCTGCTGGAACAGGAAGTCGAGCGCAAGGACCGTATTGTCGCGCTCGGCGGAGGCGT
GATCGGCGATCTCACCGGGTTTGCCGCCTCGATCGTCAAGCGTGGCTGCGGTTTCATCCAGATCCCGACGACCCTCCTGG
CGCAGGTCGATTCCAGCGTCGGCGGAAAGACCGCGATCAACACGCCCGCTGGCAAGAACCTCGTCGGCGCGTTTCACCAG
CCTGCGCTGGTCCTCGCCGATCCGCTCGCGCTCGACACGCTGCCGCTGCGCGATGTGCGGGCCGGGTACGCCGAAGTGGT
GAAATATGGCCTGATCGACGATGCGCCCTTCTTCGAGTGGTGTGAGGCGAACGGCGCAAAGCTCCTCGCAGGCGACCTGG
CAGCGCGCGAGACGGCCATCGCACACAGCGTCGCGGCAAAGGCGCGGATCGTGGCGGCGGACGAGAAGGAAATCGCCGGC
ATCCGTGCGCTACTCAATCTCGGGCACACTTTCGGGCACGCGCTCGAGGCCGAGACCGGCTTTACCGATCGCCTGCACCA
TGGCGAAGGCGTGGCGCTGGGGATGGTGCTGGCGGCACGATTCTCGGCGCGGCAGGGGCTGATGTCGAGGCAGGATGCCG
AACGCGTGGCTCGCCATGTCGAAGCGGTGGGCCTGCCTGCCACGCTCCGCGAGCTTGGGCTTTCCTGCGACGGCCGCCGC
CTTGCCGATCACATGCTTCACGACAAGAAGATGGACGCGGGCACATTGCCCTTCCTTCTCATGCGCGGGATCGGGCAGAC
CTTCCTGGCAAAGGACGTCGATCTGACGGAAGTGGCCGCTTTCCTCGACGAGGAACTCGCCAGAACCTGA

Upstream 100 bases:

>100_bases
ACGAGCGCGAGCCGTTCTATGCGCAAGCGCCGATCCACATGACCAGCGGGGCGCAACCGCACCAAGTCACGGCAAGCAAG
ATATTGAGGGCAATCGATCA

Downstream 100 bases:

>100_bases
TCATGTGTCTTCGGGCAGAAGGTCGACCACTTTGAAGCCCGGCAGGACCGCCTTGCGCAGGAGCGTGCGGTGGCAACCGT
GCGCCTCGCGTTCATAGCAC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MAVIPVAIAGAPYEVRIEAGVLARAGEHCRPFLRKDRVAIVTDEHVAAEWRETVTASFDSVGVRSEWLVLPAGESTKSWE
HLARLVDWLLEQEVERKDRIVALGGGVIGDLTGFAASIVKRGCGFIQIPTTLLAQVDSSVGGKTAINTPAGKNLVGAFHQ
PALVLADPLALDTLPLRDVRAGYAEVVKYGLIDDAPFFEWCEANGAKLLAGDLAARETAIAHSVAAKARIVAADEKEIAG
IRALLNLGHTFGHALEAETGFTDRLHHGEGVALGMVLAARFSARQGLMSRQDAERVARHVEAVGLPATLRELGLSCDGRR
LADHMLHDKKMDAGTLPFLLMRGIGQTFLAKDVDLTEVAAFLDEELART

Sequences:

>Translated_369_residues
MAVIPVAIAGAPYEVRIEAGVLARAGEHCRPFLRKDRVAIVTDEHVAAEWRETVTASFDSVGVRSEWLVLPAGESTKSWE
HLARLVDWLLEQEVERKDRIVALGGGVIGDLTGFAASIVKRGCGFIQIPTTLLAQVDSSVGGKTAINTPAGKNLVGAFHQ
PALVLADPLALDTLPLRDVRAGYAEVVKYGLIDDAPFFEWCEANGAKLLAGDLAARETAIAHSVAAKARIVAADEKEIAG
IRALLNLGHTFGHALEAETGFTDRLHHGEGVALGMVLAARFSARQGLMSRQDAERVARHVEAVGLPATLRELGLSCDGRR
LADHMLHDKKMDAGTLPFLLMRGIGQTFLAKDVDLTEVAAFLDEELART
>Mature_368_residues
AVIPVAIAGAPYEVRIEAGVLARAGEHCRPFLRKDRVAIVTDEHVAAEWRETVTASFDSVGVRSEWLVLPAGESTKSWEH
LARLVDWLLEQEVERKDRIVALGGGVIGDLTGFAASIVKRGCGFIQIPTTLLAQVDSSVGGKTAINTPAGKNLVGAFHQP
ALVLADPLALDTLPLRDVRAGYAEVVKYGLIDDAPFFEWCEANGAKLLAGDLAARETAIAHSVAAKARIVAADEKEIAGI
RALLNLGHTFGHALEAETGFTDRLHHGEGVALGMVLAARFSARQGLMSRQDAERVARHVEAVGLPATLRELGLSCDGRRL
ADHMLHDKKMDAGTLPFLLMRGIGQTFLAKDVDLTEVAAFLDEELART

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=348, Percent_Identity=45.1149425287356, Blast_Score=250, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6320332, Length=321, Percent_Identity=37.0716510903427, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39581; Mature: 39450

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVIPVAIAGAPYEVRIEAGVLARAGEHCRPFLRKDRVAIVTDEHVAAEWRETVTASFDS
CCEEEEEECCCCEEEEEECCHHHHCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHC
VGVRSEWLVLPAGESTKSWEHLARLVDWLLEQEVERKDRIVALGGGVIGDLTGFAASIVK
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHH
RGCGFIQIPTTLLAQVDSSVGGKTAINTPAGKNLVGAFHQPALVLADPLALDTLPLRDVR
CCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCHHHHHCCCCEEEECCHHHCCCCHHHHH
AGYAEVVKYGLIDDAPFFEWCEANGAKLLAGDLAARETAIAHSVAAKARIVAADEKEIAG
HHHHHHHHHCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHEEEECCCHHHHH
IRALLNLGHTFGHALEAETGFTDRLHHGEGVALGMVLAARFSARQGLMSRQDAERVARHV
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVGLPATLRELGLSCDGRRLADHMLHDKKMDAGTLPFLLMRGIGQTFLAKDVDLTEVAA
HHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHCCCCHHHHHH
FLDEELART
HHHHHHHCC
>Mature Secondary Structure 
AVIPVAIAGAPYEVRIEAGVLARAGEHCRPFLRKDRVAIVTDEHVAAEWRETVTASFDS
CEEEEEECCCCEEEEEECCHHHHCCHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHC
VGVRSEWLVLPAGESTKSWEHLARLVDWLLEQEVERKDRIVALGGGVIGDLTGFAASIVK
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHH
RGCGFIQIPTTLLAQVDSSVGGKTAINTPAGKNLVGAFHQPALVLADPLALDTLPLRDVR
CCCCEEEEHHHHHHHHHHCCCCCEEECCCCCCCHHHHHCCCCEEEECCHHHCCCCHHHHH
AGYAEVVKYGLIDDAPFFEWCEANGAKLLAGDLAARETAIAHSVAAKARIVAADEKEIAG
HHHHHHHHHCCCCCCCHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHEEEECCCHHHHH
IRALLNLGHTFGHALEAETGFTDRLHHGEGVALGMVLAARFSARQGLMSRQDAERVARHV
HHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVGLPATLRELGLSCDGRRLADHMLHDKKMDAGTLPFLLMRGIGQTFLAKDVDLTEVAA
HHCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHCCCCHHHHHH
FLDEELART
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA