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The map label for this gene is zraR [H]

Identifier: 87199859

GI number: 87199859

Start: 1941856

End: 1943274

Strand: Reverse

Name: zraR [H]

Synonym: Saro_1842

Alternate gene names: 87199859

Gene position: 1943274-1941856 (Counterclockwise)

Preceding gene: 87199871

Following gene: 87199855

Centisome position: 54.56

GC content: 67.86

Gene sequence:

>1419_bases
ATGCAGGAGTCCGAACAGCGCCTTCTCATGCTGATCGACGATGAACCCGCGCAGTGCCGCCTGATTTCGGCGCTGGCATC
GCGGGAGGGGTGGCGCACGATCATCGCGCGCGATTCCGAAAGCGCGATCGCCACGCTCGGCACCCGCCAGGGCATGCAGC
TCGGCGCGATCATCCTCGACCAGTGGGTGCCAGGCGACGATGCCTGCACCCTTATCGCCGAACTCAAGGCGCGGCGCCCC
GCCCTGCCGATCCTGATGCTGACGACAAGCAGTTCGCCGCTTCTCGCGGTCGAAGCGATGCGCGCCGGGGCCACCGACTA
TCTCATCAAGCCGGTCGCACCCGAGCGCCTGCTCCAGGCGTTGCGCAGCGCCACCTCGCGCGAGACCAGCGCGAGCGAGT
TGCAACCGCTGACCGAGAAGATCGGCGCGACGCTCGACTTCGATTCGATGATCGGCGCCTCGCCCGCGTTCCGGGCCGCG
CTGGCTGTCGCGGCAAAGGCCGCTCGCACGCACGGCACCGTCCTGATCGAAGGCGAAAGCGGCACCGGCAAGGAAATGCT
CGTCCGCGCCATGCACGCCGCTAGCCCACGCGCCAAGGCGCCCTTGCGCATCGTCAATGCCGGCGGCACTTCGGCCAGCC
AACTCGAATCCGCCCTGTTCGGGCATGAAAAAGGCGCCTTCCCCGGCGCATTCGAACGCAACATCGGCATGTTCCAGCAT
GCAGACGGCGGCACGCTGGTGATCGACGAGGTCGACCGACTTCCAGCGTCCGTCCAGGAACGGCTCGTGCGTTTCCTCAC
GCGGGGGGACATCCAGCCCGTGGGCGCGCGCCACTCGTTCCGGGTCGATGTACGCCTCATCGTCTGCGCCAACGCGGGCT
TGCGCGACCTCGTCCATATCGGCGATTTCGACGCTGACCTTCATGCCCTGCTGACGCAGACGCAGGTCCAGCTTCCGTCC
TTGCGCGAACGGCCCGCCGACATCCCGGCTCTTGCCCGCCATTTCCTGGCGCGCATCGGCGAGCAGCCGGGGCTCAGGCC
GCTCGGCATCACCGACGGCGCCCTCGCCCTGCTTGCCGCCTACGACTGGCCAGGCAATGTTCGGCAATTGCAGGCCACAC
TGTTCCGCGCCGCCGTGTTCTGCGACGGCGAGGCGCTGACCGCGCAGGATTTCCCGAGCCTTTCGAACATGATCGGCGAA
GGAAGCCGCCGCGCGCCCAGCGTTACGGACGGAGCCGGCATCACTCTGTTCGCGGCCGACGGAAACCTGCGCCCGCTGGA
AGACATCGAAGCGGACGTCATCCGCCTGGCCATCGGCCACTATCGCGGCCGCATGACCGAGGTCGCCAGAAGGCTCGGCA
TCGGGCGCTCGACGCTCTACCGCAAGCTGTCCGAGCTCGGGATCGACAACGCGGCCTGA

Upstream 100 bases:

>100_bases
TCAACGCCGGAACGGTCGGATCGCGCTTAATCGCCTCTTTACCCAATCTGGCTATTGGTTTGCTCCTGACGCAAATGCGG
GGGAGTCAAAAGACTAGGTC

Downstream 100 bases:

>100_bases
CGTCAGGCCAGTTGGCTGAAATCCGTCAACGCCGCGTCGCGCAGCCCGCGCCAGACATGCAGGGCCTGAACCGTCTCGGC
CACATCGTGAACGCGGACCA

Product: two component sigma-54 specific Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MQESEQRLLMLIDDEPAQCRLISALASREGWRTIIARDSESAIATLGTRQGMQLGAIILDQWVPGDDACTLIAELKARRP
ALPILMLTTSSSPLLAVEAMRAGATDYLIKPVAPERLLQALRSATSRETSASELQPLTEKIGATLDFDSMIGASPAFRAA
LAVAAKAARTHGTVLIEGESGTGKEMLVRAMHAASPRAKAPLRIVNAGGTSASQLESALFGHEKGAFPGAFERNIGMFQH
ADGGTLVIDEVDRLPASVQERLVRFLTRGDIQPVGARHSFRVDVRLIVCANAGLRDLVHIGDFDADLHALLTQTQVQLPS
LRERPADIPALARHFLARIGEQPGLRPLGITDGALALLAAYDWPGNVRQLQATLFRAAVFCDGEALTAQDFPSLSNMIGE
GSRRAPSVTDGAGITLFAADGNLRPLEDIEADVIRLAIGHYRGRMTEVARRLGIGRSTLYRKLSELGIDNAA

Sequences:

>Translated_472_residues
MQESEQRLLMLIDDEPAQCRLISALASREGWRTIIARDSESAIATLGTRQGMQLGAIILDQWVPGDDACTLIAELKARRP
ALPILMLTTSSSPLLAVEAMRAGATDYLIKPVAPERLLQALRSATSRETSASELQPLTEKIGATLDFDSMIGASPAFRAA
LAVAAKAARTHGTVLIEGESGTGKEMLVRAMHAASPRAKAPLRIVNAGGTSASQLESALFGHEKGAFPGAFERNIGMFQH
ADGGTLVIDEVDRLPASVQERLVRFLTRGDIQPVGARHSFRVDVRLIVCANAGLRDLVHIGDFDADLHALLTQTQVQLPS
LRERPADIPALARHFLARIGEQPGLRPLGITDGALALLAAYDWPGNVRQLQATLFRAAVFCDGEALTAQDFPSLSNMIGE
GSRRAPSVTDGAGITLFAADGNLRPLEDIEADVIRLAIGHYRGRMTEVARRLGIGRSTLYRKLSELGIDNAA
>Mature_472_residues
MQESEQRLLMLIDDEPAQCRLISALASREGWRTIIARDSESAIATLGTRQGMQLGAIILDQWVPGDDACTLIAELKARRP
ALPILMLTTSSSPLLAVEAMRAGATDYLIKPVAPERLLQALRSATSRETSASELQPLTEKIGATLDFDSMIGASPAFRAA
LAVAAKAARTHGTVLIEGESGTGKEMLVRAMHAASPRAKAPLRIVNAGGTSASQLESALFGHEKGAFPGAFERNIGMFQH
ADGGTLVIDEVDRLPASVQERLVRFLTRGDIQPVGARHSFRVDVRLIVCANAGLRDLVHIGDFDADLHALLTQTQVQLPS
LRERPADIPALARHFLARIGEQPGLRPLGITDGALALLAAYDWPGNVRQLQATLFRAAVFCDGEALTAQDFPSLSNMIGE
GSRRAPSVTDGAGITLFAADGNLRPLEDIEADVIRLAIGHYRGRMTEVARRLGIGRSTLYRKLSELGIDNAA

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=456, Percent_Identity=37.280701754386, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1788550, Length=464, Percent_Identity=32.5431034482759, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI1790299, Length=426, Percent_Identity=38.2629107981221, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788905, Length=463, Percent_Identity=31.7494600431965, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI87082117, Length=357, Percent_Identity=35.8543417366947, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1789087, Length=350, Percent_Identity=34.8571428571429, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI87082152, Length=329, Percent_Identity=36.7781155015198, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1789233, Length=327, Percent_Identity=32.7217125382263, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI87081872, Length=262, Percent_Identity=38.5496183206107, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1787583, Length=323, Percent_Identity=32.8173374613003, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1786524, Length=332, Percent_Identity=33.433734939759, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081858, Length=336, Percent_Identity=29.4642857142857, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789828, Length=255, Percent_Identity=30.5882352941176, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50619; Mature: 50619

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESEQRLLMLIDDEPAQCRLISALASREGWRTIIARDSESAIATLGTRQGMQLGAIILD
CCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHC
QWVPGDDACTLIAELKARRPALPILMLTTSSSPLLAVEAMRAGATDYLIKPVAPERLLQA
CCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHHHHCCCCHHEECCCCHHHHHHH
LRSATSRETSASELQPLTEKIGATLDFDSMIGASPAFRAALAVAAKAARTHGTVLIEGES
HHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCC
GTGKEMLVRAMHAASPRAKAPLRIVNAGGTSASQLESALFGHEKGAFPGAFERNIGMFQH
CCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCEEE
ADGGTLVIDEVDRLPASVQERLVRFLTRGDIQPVGARHSFRVDVRLIVCANAGLRDLVHI
CCCCEEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHC
GDFDADLHALLTQTQVQLPSLRERPADIPALARHFLARIGEQPGLRPLGITDGALALLAA
CCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEE
YDWPGNVRQLQATLFRAAVFCDGEALTAQDFPSLSNMIGEGSRRAPSVTDGAGITLFAAD
CCCCCCHHHHHHHHHHHHHEECCCCCCHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEECC
GNLRPLEDIEADVIRLAIGHYRGRMTEVARRLGIGRSTLYRKLSELGIDNAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQESEQRLLMLIDDEPAQCRLISALASREGWRTIIARDSESAIATLGTRQGMQLGAIILD
CCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCHHHHHHHC
QWVPGDDACTLIAELKARRPALPILMLTTSSSPLLAVEAMRAGATDYLIKPVAPERLLQA
CCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEHHHHHCCCCHHEECCCCHHHHHHH
LRSATSRETSASELQPLTEKIGATLDFDSMIGASPAFRAALAVAAKAARTHGTVLIEGES
HHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCC
GTGKEMLVRAMHAASPRAKAPLRIVNAGGTSASQLESALFGHEKGAFPGAFERNIGMFQH
CCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCEEE
ADGGTLVIDEVDRLPASVQERLVRFLTRGDIQPVGARHSFRVDVRLIVCANAGLRDLVHI
CCCCEEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHC
GDFDADLHALLTQTQVQLPSLRERPADIPALARHFLARIGEQPGLRPLGITDGALALLAA
CCCCHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHEE
YDWPGNVRQLQATLFRAAVFCDGEALTAQDFPSLSNMIGEGSRRAPSVTDGAGITLFAAD
CCCCCCHHHHHHHHHHHHHEECCCCCCHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEECC
GNLRPLEDIEADVIRLAIGHYRGRMTEVARRLGIGRSTLYRKLSELGIDNAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]