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The map label for this gene is yciK [H]

Identifier: 87199779

GI number: 87199779

Start: 1857722

End: 1858453

Strand: Reverse

Name: yciK [H]

Synonym: Saro_1762

Alternate gene names: 87199779

Gene position: 1858453-1857722 (Counterclockwise)

Preceding gene: 87199780

Following gene: 87199778

Centisome position: 52.18

GC content: 67.08

Gene sequence:

>732_bases
ATGAGCGCGCAGGGTTCGCAGGACGGCCGCTTTGCCGGCCAGTTGGCGCTCGTCACCGGCGCGAGCCGGGGCATCGGTGC
CGCCACGGCAAAGGCGCTTGCCGCACAGGGCGCGCATGTCGTACTCGTGGCCCGGACCGCCAAGGAGCTTGAAAAGGTCG
AGGAAGAGATCTTCGAGGCTGGCGGCAGCGCGACGATCGCTCCGGTCGACCTGTCCGAGCCCGAAGGCATCGCCCGCCTT
GCCACCGCGATCTCGGGCCGCTGGAGCGCGCTCGACGTACTCGTCATAAACGCCGCCGCCTTCCCCACGCTGACACCGGT
CTGGCAGATCGACTCGCGCGAGTTCAACAATGCGCTGACGCTGAACGTCCTCGCCACGCAGGCGCTGCTCGCCGGTTTCG
ACGGCATGCTGAAGAAGAGCAAGGACGCCCGCGTCATCGGCGTGACCAGCAGCGTCGGCGCGACGCCGCGCGCCTACTGG
GGCGCCTATGGCGCGTCGAAGGCCGCGTTCGACGTCCTGCTCGACTGCTACGCGCAGGAAGTGCGCAACACCTCGGCCGT
GCGCGTCGCAATTCTCGATCCGGGCGCCACGCGCACCAAGATGCGCGCAAGGGCCTATCCCGGCGAAAACCCGGAAAGCG
TGAAGGCGCCCGAAGTCGTTGCCGAACGAATGGTTGCGCTTCTTGGTGAACAATTTTCCAGTCCGCACCGCGAACGCGTT
AACCAGGACTGA

Upstream 100 bases:

>100_bases
CGACGCCTGCTTCACCGGCGACTACCCCACGCGGCTGACCGACCTCGCAGAGCGCGAGAATCCGGACCAGCTTTCGCTGC
CGGTCGAAAAGGTCGCCTGA

Downstream 100 bases:

>100_bases
CAGCCGCGAATTAACGGAAATCGGCGATTCTCTGCGCTTCCGGGAGGAATCCTTTCCGGGCAGATGAAACGGGTCCGGGA
CGTTCGGCATGAACACCACC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSAQGSQDGRFAGQLALVTGASRGIGAATAKALAAQGAHVVLVARTAKELEKVEEEIFEAGGSATIAPVDLSEPEGIARL
ATAISGRWSALDVLVINAAAFPTLTPVWQIDSREFNNALTLNVLATQALLAGFDGMLKKSKDARVIGVTSSVGATPRAYW
GAYGASKAAFDVLLDCYAQEVRNTSAVRVAILDPGATRTKMRARAYPGENPESVKAPEVVAERMVALLGEQFSSPHRERV
NQD

Sequences:

>Translated_243_residues
MSAQGSQDGRFAGQLALVTGASRGIGAATAKALAAQGAHVVLVARTAKELEKVEEEIFEAGGSATIAPVDLSEPEGIARL
ATAISGRWSALDVLVINAAAFPTLTPVWQIDSREFNNALTLNVLATQALLAGFDGMLKKSKDARVIGVTSSVGATPRAYW
GAYGASKAAFDVLLDCYAQEVRNTSAVRVAILDPGATRTKMRARAYPGENPESVKAPEVVAERMVALLGEQFSSPHRERV
NQD
>Mature_242_residues
SAQGSQDGRFAGQLALVTGASRGIGAATAKALAAQGAHVVLVARTAKELEKVEEEIFEAGGSATIAPVDLSEPEGIARLA
TAISGRWSALDVLVINAAAFPTLTPVWQIDSREFNNALTLNVLATQALLAGFDGMLKKSKDARVIGVTSSVGATPRAYWG
AYGASKAAFDVLLDCYAQEVRNTSAVRVAILDPGATRTKMRARAYPGENPESVKAPEVVAERMVALLGEQFSSPHRERVN
QD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=33.195020746888, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI7705855, Length=230, Percent_Identity=27.3913043478261, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI32455239, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI5031765, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI40254986, Length=189, Percent_Identity=29.1005291005291, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4557649, Length=217, Percent_Identity=26.7281105990783, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI32483357, Length=208, Percent_Identity=28.8461538461538, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787526, Length=233, Percent_Identity=33.0472103004292, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786701, Length=213, Percent_Identity=24.8826291079812, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787335, Length=191, Percent_Identity=27.7486910994764, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082100, Length=217, Percent_Identity=29.4930875576037, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=197, Percent_Identity=33.502538071066, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787820, Length=190, Percent_Identity=25.7894736842105, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1786812, Length=226, Percent_Identity=28.3185840707965, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=241, Percent_Identity=30.2904564315353, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=198, Percent_Identity=34.3434343434343, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=214, Percent_Identity=34.1121495327103, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17532791, Length=148, Percent_Identity=33.1081081081081, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=221, Percent_Identity=27.1493212669683, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=215, Percent_Identity=32.093023255814, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=209, Percent_Identity=32.5358851674641, Blast_Score=70, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=217, Percent_Identity=29.9539170506912, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=198, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=233, Percent_Identity=27.8969957081545, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17558628, Length=177, Percent_Identity=28.8135593220339, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=204, Percent_Identity=31.3725490196078, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555612, Length=248, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=148, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=209, Percent_Identity=29.1866028708134, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=215, Percent_Identity=31.1627906976744, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=201, Percent_Identity=30.3482587064677, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644339, Length=209, Percent_Identity=32.5358851674641, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358495, Length=224, Percent_Identity=26.3392857142857, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357041, Length=197, Percent_Identity=30.4568527918782, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=34.5177664974619, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28571526, Length=197, Percent_Identity=30.9644670050761, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357673, Length=234, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24643142, Length=204, Percent_Identity=31.3725490196078, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25536; Mature: 25405

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQGSQDGRFAGQLALVTGASRGIGAATAKALAAQGAHVVLVARTAKELEKVEEEIFEA
CCCCCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHC
GGSATIAPVDLSEPEGIARLATAISGRWSALDVLVINAAAFPTLTPVWQIDSREFNNALT
CCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEE
LNVLATQALLAGFDGMLKKSKDARVIGVTSSVGATPRAYWGAYGASKAAFDVLLDCYAQE
EHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
VRNTSAVRVAILDPGATRTKMRARAYPGENPESVKAPEVVAERMVALLGEQFSSPHRERV
HCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHC
NQD
CCC
>Mature Secondary Structure 
SAQGSQDGRFAGQLALVTGASRGIGAATAKALAAQGAHVVLVARTAKELEKVEEEIFEA
CCCCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHC
GGSATIAPVDLSEPEGIARLATAISGRWSALDVLVINAAAFPTLTPVWQIDSREFNNALT
CCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEE
LNVLATQALLAGFDGMLKKSKDARVIGVTSSVGATPRAYWGAYGASKAAFDVLLDCYAQE
EHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
VRNTSAVRVAILDPGATRTKMRARAYPGENPESVKAPEVVAERMVALLGEQFSSPHRERV
HCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHC
NQD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]