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The map label for this gene is iorA [H]

Identifier: 87199720

GI number: 87199720

Start: 1788834

End: 1789337

Strand: Reverse

Name: iorA [H]

Synonym: Saro_1703

Alternate gene names: 87199720

Gene position: 1789337-1788834 (Counterclockwise)

Preceding gene: 87199726

Following gene: 87199719

Centisome position: 50.24

GC content: 68.45

Gene sequence:

>504_bases
ATGGGCGTCACCCTCACCATCAATGGCCGCAAACGCGTGGTCGAAGCCGAAGCGGACAAGCCCTTGCTGTGGGTTCTGCG
GGAAGACCTCGACATGCCCGGAACCAAGTTCGGCTGCGGCGCCGGGCTGTGCGGTGCCTGCACCGTCCATCTCGATGGCG
AGGCGATCCGCTCGTGCCAGACGCCGATTGCCGACGCGGCGGGCAAGGCCGTCACCACGATCGAGGGCGTCGGCGCAGAT
CCGGTCGGAAAGCGCGTACAGAACGCCTGGATCGCGCTCGACGTGCCGCAGTGCGGATATTGCCAGGCTGGACAGATCAT
GTCGGCCACCGCGCTCCTCCGCCAGACGCCCAAGCCCAGCGCCGAAGACATCGACGGCTGGATGAGCGGCAACATCTGCC
GCTGCGCCACTTACCTGCGCATCCGCGCCGCCATCCGCCAGGCCGCCGGGCTCCCGGCCGAGATCGCCGATGCAGGCAAC
GCCTTCGGGGAGGCCTCGGCATGA

Upstream 100 bases:

>100_bases
GACCATGCCTTGATGCCTGTCCAGATTCAGACCATTGCGGGCTCGGGCATGGCACCTGCCAGGCCGGGCCCCAGCGAACA
AAATCAAGGAAAAGAAGGCG

Downstream 100 bases:

>100_bases
CCGTCGCCGCCGGCCTCTCCCGCCGCTCGTTCCTCGTCGCCTCGCTTGCCGGAGGCGCGGTCCTGACGCTCGACGCCTCG
ATCGCGCTGGCGGCCCCGCA

Product: (2Fe-2S)-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MGVTLTINGRKRVVEAEADKPLLWVLREDLDMPGTKFGCGAGLCGACTVHLDGEAIRSCQTPIADAAGKAVTTIEGVGAD
PVGKRVQNAWIALDVPQCGYCQAGQIMSATALLRQTPKPSAEDIDGWMSGNICRCATYLRIRAAIRQAAGLPAEIADAGN
AFGEASA

Sequences:

>Translated_167_residues
MGVTLTINGRKRVVEAEADKPLLWVLREDLDMPGTKFGCGAGLCGACTVHLDGEAIRSCQTPIADAAGKAVTTIEGVGAD
PVGKRVQNAWIALDVPQCGYCQAGQIMSATALLRQTPKPSAEDIDGWMSGNICRCATYLRIRAAIRQAAGLPAEIADAGN
AFGEASA
>Mature_166_residues
GVTLTINGRKRVVEAEADKPLLWVLREDLDMPGTKFGCGAGLCGACTVHLDGEAIRSCQTPIADAAGKAVTTIEGVGADP
VGKRVQNAWIALDVPQCGYCQAGQIMSATALLRQTPKPSAEDIDGWMSGNICRCATYLRIRAAIRQAAGLPAEIADAGNA
FGEASA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=160, Percent_Identity=40, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI71773480, Length=86, Percent_Identity=37.2093023255814, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1786480, Length=165, Percent_Identity=41.2121212121212, Blast_Score=119, Evalue=7e-29,
Organism=Escherichia coli, GI1789232, Length=141, Percent_Identity=39.7163120567376, Blast_Score=83, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=154, Percent_Identity=39.6103896103896, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=35.2564102564103, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566215, Length=156, Percent_Identity=33.974358974359, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737937, Length=153, Percent_Identity=40.5228758169935, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647193, Length=177, Percent_Identity=34.4632768361582, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=31.6455696202532, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24647199, Length=171, Percent_Identity=32.1637426900585, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24647197, Length=187, Percent_Identity=31.0160427807487, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647195, Length=187, Percent_Identity=31.0160427807487, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 17373; Mature: 17242

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVTLTINGRKRVVEAEADKPLLWVLREDLDMPGTKFGCGAGLCGACTVHLDGEAIRSCQ
CCEEEEECCCEEEEECCCCCCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHC
TPIADAAGKAVTTIEGVGADPVGKRVQNAWIALDVPQCGYCQAGQIMSATALLRQTPKPS
CCHHHHCCCEEEEECCCCCCHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCC
AEDIDGWMSGNICRCATYLRIRAAIRQAAGLPAEIADAGNAFGEASA
HHHCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GVTLTINGRKRVVEAEADKPLLWVLREDLDMPGTKFGCGAGLCGACTVHLDGEAIRSCQ
CEEEEECCCEEEEECCCCCCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEECHHHHHHHC
TPIADAAGKAVTTIEGVGADPVGKRVQNAWIALDVPQCGYCQAGQIMSATALLRQTPKPS
CCHHHHCCCEEEEECCCCCCHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCC
AEDIDGWMSGNICRCATYLRIRAAIRQAAGLPAEIADAGNAFGEASA
HHHCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]