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The map label for this gene is accA1 [H]

Identifier: 87199659

GI number: 87199659

Start: 1716319

End: 1718190

Strand: Reverse

Name: accA1 [H]

Synonym: Saro_1642

Alternate gene names: 87199659

Gene position: 1718190-1716319 (Counterclockwise)

Preceding gene: 87199660

Following gene: 87199658

Centisome position: 48.24

GC content: 67.36

Gene sequence:

>1872_bases
ATGATCAAATCCCTCCTCGTCGCCAATCGCGGCGAAATTGCCTGTCGCGTGATCCGTACAGCGCGGCGCATGGGCGTTCG
CACAGTGGCGGTCTATTCCGATGCCGATGCCAATGCCCTGCACGTCCGCTCGGCCGACGAAGCAGTCCACATAGGTCCGG
CAGCAGCGCGCGAAAGCTATCTGGTGGGAGAGCGCATCATTGCCGCCGCGCTCACCACTGGCGCTGAGGCCATCCACCCC
GGCTATGGGTTCCTCTCGGAGAATGCCGAGTTCGCTCAGGCCGTTCTCGACGCGGGCCTGGTCTGGGTTGGCCCGAAGCC
GCACTCGATCACCGCGATGGGCCTCAAGGACGCCGCCAAGGCCCGCATGATCGCGGCAGGCGTGCCGGTGACGCCGGGAT
ATCTGGGCGAGGATCAATCGGCGGAGCGATTGCAGGCCGAGGCCGACGCCATCGGCTACCCGGTACTGATCAAGGCCGTC
GCGGGCGGAGGCGGCAAGGGCATGCGGCGCGTCGATGCCGCGGCGGACTTTGCCGAAGCGCTCGCCTCGTGCCGCCGTGA
GGCTGCCTCCTCGTTCGGCGACGACCGTGTGCTTATCGAGAAGTACATCCTTTCCCCGCGGCACATTGAGGTTCAGGTCT
TCGGCGACGCCCACGGCAACGTCGTCCACCTGTTCGAACGCGACTGCTCGCTTCAGCGGCGGCACCAGAAGGTGATCGAG
GAGGCCCCTGCGCCCGGCATGGACGAAGCGACCCGCGAGGCTGTCTGCGCGGCCGCCGTCCGCGCGGCCAAGGCGGTCGA
CTATGAAGGCGCGGGCACCATCGAATTCATCGCCGATGGCTCCGAAGGCCTGCGCGCGGACCGGATCTGGTTCATGGAAA
TGAACACGCGCCTGCAGGTGGAACATCCGGTGACCGAGGAGATCACCGGCGTCGACCTCGTCGAATGGCAGCTCCGCGTC
GCGTCGGGTGAGCCGCTGCCCAAGCGGCAAGACGAGCTATCGATCAACGGCTGGGCGATGGAAGCCCGGCTCTACGCCGA
GGACCCGACCCGGGGCTTCCTGCCCAGCATCGGGCGCGTCGACGATTTCCACTTCCCGCACCATCATGCGCGCATTGATA
CGGGGGTAGAGGCGGGCGCGGAAATCTCGCCCTTCTACGATCCGATGATCGCCAAGCTCATCGTCCACCGCCCGACCCGG
ACTGAAGCCGTCTCTGCGCTGCGCGAGACACTTGACGAAGGCATCGTCGGACCGCTCGTCACCAACAGCGGCTTCCTCTG
GCGCCTGCTGGGCCACGCGGCGTTCGAGGCCGGGGTCGTCGACACCGGCCTGATCGAGCGCAATCTCGAAACCCTCGCCA
CCCGGCCCGAGCCTTCCCGCGAGGGTCTGGCTCTGGCCGCAATGCGCCTTGCCGGCACGCCGGGCGCGACGCCATGGTCG
AGCCGGTCCGGCTTCCGCATGAACGCTGCCCCGCGCCGCGACGTTCGTCTTTCCGACCAGTTCGGCCGGACGTTCACGAC
CGAACTGCCACCCGAACCGGCGTTCGACTACTGGCCCGGCGAAGACGCGACGACGATCGACGAAGGTGGCGAGCGCTTTC
GCGTGCGCCTGGCGCGGGCCGACGGGGGCTCCGGCGGCGCAGCCTCGGATGGGGCCATCCTCGCCCCCATGCCCGGCAAG
GTCATCTCGGTCGATGTATCCGCAGGCCAGTCGGTGACCAAGGGCCAGAAACTCATGGTGCTCGAGGCAATGAAGATGGA
ACATGCCCTCACCGCCCCCTTCGACGGTGTCGTGGCCGAACTCAACGCCGCGCCGGGCGGACAGGTTCAGGTCGAGGCAC
TGCTGGCGAAGATCGAAAAGGGAGAAGCCTGA

Upstream 100 bases:

>100_bases
CCCGCGACGTGCTGGGGCTCGCCCTCGAGGCCTGTCTCGAAGCGCCGATTGCGGAGGCGCCCCGGTTCGGGGTGTTCAGG
ATGTGATGGAGGCCAGACCG

Downstream 100 bases:

>100_bases
TGGCTGGCAAGTTCTTCGACGAGTGGCAGGTGGGCGACCGGATCAGCCACGAAATCCGCCGCACCGTGACAGAGACCGAC
AATCTCCTGTTCTCGACCAT

Product: carbamoyl-phosphate synthase L chain, ATP-binding

Products: NA

Alternate protein names: Biotin carboxylase; Biotin carboxyl carrier protein; BCCP [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MIKSLLVANRGEIACRVIRTARRMGVRTVAVYSDADANALHVRSADEAVHIGPAAARESYLVGERIIAAALTTGAEAIHP
GYGFLSENAEFAQAVLDAGLVWVGPKPHSITAMGLKDAAKARMIAAGVPVTPGYLGEDQSAERLQAEADAIGYPVLIKAV
AGGGGKGMRRVDAAADFAEALASCRREAASSFGDDRVLIEKYILSPRHIEVQVFGDAHGNVVHLFERDCSLQRRHQKVIE
EAPAPGMDEATREAVCAAAVRAAKAVDYEGAGTIEFIADGSEGLRADRIWFMEMNTRLQVEHPVTEEITGVDLVEWQLRV
ASGEPLPKRQDELSINGWAMEARLYAEDPTRGFLPSIGRVDDFHFPHHHARIDTGVEAGAEISPFYDPMIAKLIVHRPTR
TEAVSALRETLDEGIVGPLVTNSGFLWRLLGHAAFEAGVVDTGLIERNLETLATRPEPSREGLALAAMRLAGTPGATPWS
SRSGFRMNAAPRRDVRLSDQFGRTFTTELPPEPAFDYWPGEDATTIDEGGERFRVRLARADGGSGGAASDGAILAPMPGK
VISVDVSAGQSVTKGQKLMVLEAMKMEHALTAPFDGVVAELNAAPGGQVQVEALLAKIEKGEA

Sequences:

>Translated_623_residues
MIKSLLVANRGEIACRVIRTARRMGVRTVAVYSDADANALHVRSADEAVHIGPAAARESYLVGERIIAAALTTGAEAIHP
GYGFLSENAEFAQAVLDAGLVWVGPKPHSITAMGLKDAAKARMIAAGVPVTPGYLGEDQSAERLQAEADAIGYPVLIKAV
AGGGGKGMRRVDAAADFAEALASCRREAASSFGDDRVLIEKYILSPRHIEVQVFGDAHGNVVHLFERDCSLQRRHQKVIE
EAPAPGMDEATREAVCAAAVRAAKAVDYEGAGTIEFIADGSEGLRADRIWFMEMNTRLQVEHPVTEEITGVDLVEWQLRV
ASGEPLPKRQDELSINGWAMEARLYAEDPTRGFLPSIGRVDDFHFPHHHARIDTGVEAGAEISPFYDPMIAKLIVHRPTR
TEAVSALRETLDEGIVGPLVTNSGFLWRLLGHAAFEAGVVDTGLIERNLETLATRPEPSREGLALAAMRLAGTPGATPWS
SRSGFRMNAAPRRDVRLSDQFGRTFTTELPPEPAFDYWPGEDATTIDEGGERFRVRLARADGGSGGAASDGAILAPMPGK
VISVDVSAGQSVTKGQKLMVLEAMKMEHALTAPFDGVVAELNAAPGGQVQVEALLAKIEKGEA
>Mature_623_residues
MIKSLLVANRGEIACRVIRTARRMGVRTVAVYSDADANALHVRSADEAVHIGPAAARESYLVGERIIAAALTTGAEAIHP
GYGFLSENAEFAQAVLDAGLVWVGPKPHSITAMGLKDAAKARMIAAGVPVTPGYLGEDQSAERLQAEADAIGYPVLIKAV
AGGGGKGMRRVDAAADFAEALASCRREAASSFGDDRVLIEKYILSPRHIEVQVFGDAHGNVVHLFERDCSLQRRHQKVIE
EAPAPGMDEATREAVCAAAVRAAKAVDYEGAGTIEFIADGSEGLRADRIWFMEMNTRLQVEHPVTEEITGVDLVEWQLRV
ASGEPLPKRQDELSINGWAMEARLYAEDPTRGFLPSIGRVDDFHFPHHHARIDTGVEAGAEISPFYDPMIAKLIVHRPTR
TEAVSALRETLDEGIVGPLVTNSGFLWRLLGHAAFEAGVVDTGLIERNLETLATRPEPSREGLALAAMRLAGTPGATPWS
SRSGFRMNAAPRRDVRLSDQFGRTFTTELPPEPAFDYWPGEDATTIDEGGERFRVRLARADGGSGGAASDGAILAPMPGK
VISVDVSAGQSVTKGQKLMVLEAMKMEHALTAPFDGVVAELNAAPGGQVQVEALLAKIEKGEA

Specific function: This protein carries two functions:biotin carboxyl carrier protein and biotin carboxyltransferase [H]

COG id: COG4770

COG function: function code I; Acetyl/propionyl-CoA carboxylase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=677, Percent_Identity=45.642540620384, Blast_Score=552, Evalue=1e-157,
Organism=Homo sapiens, GI295821183, Length=642, Percent_Identity=40.9657320872274, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI189095269, Length=444, Percent_Identity=50, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI65506442, Length=444, Percent_Identity=50, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI106049528, Length=465, Percent_Identity=44.7311827956989, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI106049295, Length=465, Percent_Identity=44.7311827956989, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI106049292, Length=465, Percent_Identity=44.7311827956989, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI38679960, Length=723, Percent_Identity=28.2157676348548, Blast_Score=225, Evalue=8e-59,
Organism=Homo sapiens, GI38679977, Length=723, Percent_Identity=28.2157676348548, Blast_Score=225, Evalue=8e-59,
Organism=Homo sapiens, GI38679967, Length=723, Percent_Identity=28.2157676348548, Blast_Score=225, Evalue=8e-59,
Organism=Homo sapiens, GI38679971, Length=723, Percent_Identity=28.2157676348548, Blast_Score=225, Evalue=9e-59,
Organism=Homo sapiens, GI38679974, Length=723, Percent_Identity=28.2157676348548, Blast_Score=225, Evalue=9e-59,
Organism=Homo sapiens, GI134142062, Length=510, Percent_Identity=30.7843137254902, Blast_Score=204, Evalue=3e-52,
Organism=Escherichia coli, GI1789654, Length=453, Percent_Identity=46.5783664459161, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71987519, Length=665, Percent_Identity=47.218045112782, Blast_Score=516, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17567343, Length=445, Percent_Identity=48.9887640449438, Blast_Score=414, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17562816, Length=468, Percent_Identity=42.5213675213675, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI71997168, Length=514, Percent_Identity=29.5719844357977, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71997163, Length=514, Percent_Identity=29.5719844357977, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI133931226, Length=496, Percent_Identity=29.8387096774194, Blast_Score=187, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6319685, Length=446, Percent_Identity=44.6188340807175, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319695, Length=456, Percent_Identity=41.0087719298246, Blast_Score=312, Evalue=8e-86,
Organism=Saccharomyces cerevisiae, GI6321376, Length=456, Percent_Identity=41.6666666666667, Blast_Score=307, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6324343, Length=714, Percent_Identity=26.6106442577031, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6323863, Length=494, Percent_Identity=29.7570850202429, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24651757, Length=670, Percent_Identity=45.6716417910448, Blast_Score=523, Evalue=1e-148,
Organism=Drosophila melanogaster, GI24651759, Length=632, Percent_Identity=44.3037974683544, Blast_Score=466, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24652212, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI24652210, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI24652214, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI19921944, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI24652216, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI281363050, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24652224, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24652222, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24652220, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI24652218, Length=473, Percent_Identity=43.7632135306554, Blast_Score=352, Evalue=4e-97,
Organism=Drosophila melanogaster, GI161076409, Length=713, Percent_Identity=28.6115007012623, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24586458, Length=713, Percent_Identity=28.6115007012623, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI161076407, Length=713, Percent_Identity=28.6115007012623, Blast_Score=216, Evalue=4e-56,
Organism=Drosophila melanogaster, GI24586460, Length=713, Percent_Identity=28.6115007012623, Blast_Score=216, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR001882
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14 [H]

Molecular weight: Translated: 66676; Mature: 66676

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50975 ATP_GRASP ; PS00136 SUBTILASE_ASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSLLVANRGEIACRVIRTARRMGVRTVAVYSDADANALHVRSADEAVHIGPAAARESY
CCCCEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCEEEECCHHHHHHH
LVGERIIAAALTTGAEAIHPGYGFLSENAEFAQAVLDAGLVWVGPKPHSITAMGLKDAAK
HHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCEEEECCHHHHH
ARMIAAGVPVTPGYLGEDQSAERLQAEADAIGYPVLIKAVAGGGGKGMRRVDAAADFAEA
HHEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LASCRREAASSFGDDRVLIEKYILSPRHIEVQVFGDAHGNVVHLFERDCSLQRRHQKVIE
HHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEEHHCCHHHHHHHHHHH
EAPAPGMDEATREAVCAAAVRAAKAVDYEGAGTIEFIADGSEGLRADRIWFMEMNTRLQV
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEECCEEEE
EHPVTEEITGVDLVEWQLRVASGEPLPKRQDELSINGWAMEARLYAEDPTRGFLPSIGRV
CCCCCHHCCCCEEEEEEEEECCCCCCCCCCCCCEECCEEEEEEEEECCCCCCCCCCCCCC
DDFHFPHHHARIDTGVEAGAEISPFYDPMIAKLIVHRPTRTEAVSALRETLDEGIVGPLV
CCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
TNSGFLWRLLGHAAFEAGVVDTGLIERNLETLATRPEPSREGLALAAMRLAGTPGATPWS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCCCCC
SRSGFRMNAAPRRDVRLSDQFGRTFTTELPPEPAFDYWPGEDATTIDEGGERFRVRLARA
CCCCEEECCCCCCCCEECHHCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEEEC
DGGSGGAASDGAILAPMPGKVISVDVSAGQSVTKGQKLMVLEAMKMEHALTAPFDGVVAE
CCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCHHHE
LNAAPGGQVQVEALLAKIEKGEA
ECCCCCCCEEHHHHHHHHHCCCC
>Mature Secondary Structure
MIKSLLVANRGEIACRVIRTARRMGVRTVAVYSDADANALHVRSADEAVHIGPAAARESY
CCCCEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCEEEECCHHHHHHH
LVGERIIAAALTTGAEAIHPGYGFLSENAEFAQAVLDAGLVWVGPKPHSITAMGLKDAAK
HHHHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHCCEEEECCCCCCEEEECCHHHHH
ARMIAAGVPVTPGYLGEDQSAERLQAEADAIGYPVLIKAVAGGGGKGMRRVDAAADFAEA
HHEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LASCRREAASSFGDDRVLIEKYILSPRHIEVQVFGDAHGNVVHLFERDCSLQRRHQKVIE
HHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEEEHHCCHHHHHHHHHHH
EAPAPGMDEATREAVCAAAVRAAKAVDYEGAGTIEFIADGSEGLRADRIWFMEMNTRLQV
HCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEEECCEEEE
EHPVTEEITGVDLVEWQLRVASGEPLPKRQDELSINGWAMEARLYAEDPTRGFLPSIGRV
CCCCCHHCCCCEEEEEEEEECCCCCCCCCCCCCEECCEEEEEEEEECCCCCCCCCCCCCC
DDFHFPHHHARIDTGVEAGAEISPFYDPMIAKLIVHRPTRTEAVSALRETLDEGIVGPLV
CCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEE
TNSGFLWRLLGHAAFEAGVVDTGLIERNLETLATRPEPSREGLALAAMRLAGTPGATPWS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCCCCC
SRSGFRMNAAPRRDVRLSDQFGRTFTTELPPEPAFDYWPGEDATTIDEGGERFRVRLARA
CCCCEEECCCCCCCCEECHHCCCEEECCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEEEC
DGGSGGAASDGAILAPMPGKVISVDVSAGQSVTKGQKLMVLEAMKMEHALTAPFDGVVAE
CCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCHHHE
LNAAPGGQVQVEALLAKIEKGEA
ECCCCCCCEEHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]