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The map label for this gene is hexR [C]

Identifier: 87199564

GI number: 87199564

Start: 1601033

End: 1601923

Strand: Reverse

Name: hexR [C]

Synonym: Saro_1547

Alternate gene names: 87199564

Gene position: 1601923-1601033 (Counterclockwise)

Preceding gene: 87199570

Following gene: 87199560

Centisome position: 44.98

GC content: 61.84

Gene sequence:

>891_bases
ATGCCTTCCAGCCCACAATCTTCCGTCACGGAAACTGCGCACCTGCCAGTTGAGAACGCGCTGACGCGGATACGCTCGGC
CCTGCCGCAAATGTCCAAGACTGCCGCGAAGATCGCAGCCTACGTGGTCGAACATCCGGCTGACGTCGTGGGCATGTCGA
TCACCGATCTCGCCGCGCTTGTGGATGCCAGCGAAGGGAGCGTGATCAACTTTTGTCGCAGCATTGGACTAGGCGGGTTC
CAGCACCTGAAATTGAGCCTGGCTCAGGAAATCGTCCAACCCGTACACTTCATCCATGAGGACCTGGAACGCGAGGATTC
CACTGAGACGGTCTGCCGAAAGGTGTTCCATTCCGGCATCCAGGCCTTGCGGGATTCGCTGTCCGTCCTAGACCCGAAGG
CCATGGCGGCCGCAGTCGACATCATCCGCGCTGCACGGCGCGTGGAAATCTACGGTATCGGGTCGAGCGCGCCGATTGCC
GAAGACGCCCACTACCGGCTCCTTCGCATCGGCCTGGACGCCCGCGTGGTGATCGACAGCCATGTCCAGGCGATCTCAGC
CTCCCGCTGCGACAAGGATGTAGCCGTGCTGACAATTTCGCACAGCGGGTCCACGAACGAAACCGTGGCCGCGACGCGGC
TCGCCCACGAGGCCGGGGCGCGAACCATCGTCATCACCAATTTCGGGCGGTCGCCGATTCAGGCCTATGCCGACGTCGTG
CTGTTCACCATGGCGCGCGAGACCCGTTTCCGAACCGAAGCGATGACCAGCCGCATCGCGCAGCTCTGTGTGATCGACGC
GCTGATCGCGGCGCTGGCGCTGGCTGACTACGATCGCTCTACAGACGTTCTCAAGCAGACGTTCGACGTACTTTCGATCA
AGCGTTTCTGA

Upstream 100 bases:

>100_bases
TATAAAATTGAGACAAAGACAGTAACAGTTTCACACCGTTGAAAAGATGTTAGGGAAGCGGAGGAGTATTCTTCCGAGTC
ACGAGGTTCTGCCCTCCACC

Downstream 100 bases:

>100_bases
CGTCGACCTCGATCCGGACAATCCCCGCGGCGGACGGAAAGCCCCGGCTTTCGAAACCATTGGAATTGCGGGGTGGCAGT
GAGAGTCTGCCACCCCGCCG

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPSSPQSSVTETAHLPVENALTRIRSALPQMSKTAAKIAAYVVEHPADVVGMSITDLAALVDASEGSVINFCRSIGLGGF
QHLKLSLAQEIVQPVHFIHEDLEREDSTETVCRKVFHSGIQALRDSLSVLDPKAMAAAVDIIRAARRVEIYGIGSSAPIA
EDAHYRLLRIGLDARVVIDSHVQAISASRCDKDVAVLTISHSGSTNETVAATRLAHEAGARTIVITNFGRSPIQAYADVV
LFTMARETRFRTEAMTSRIAQLCVIDALIAALALADYDRSTDVLKQTFDVLSIKRF

Sequences:

>Translated_296_residues
MPSSPQSSVTETAHLPVENALTRIRSALPQMSKTAAKIAAYVVEHPADVVGMSITDLAALVDASEGSVINFCRSIGLGGF
QHLKLSLAQEIVQPVHFIHEDLEREDSTETVCRKVFHSGIQALRDSLSVLDPKAMAAAVDIIRAARRVEIYGIGSSAPIA
EDAHYRLLRIGLDARVVIDSHVQAISASRCDKDVAVLTISHSGSTNETVAATRLAHEAGARTIVITNFGRSPIQAYADVV
LFTMARETRFRTEAMTSRIAQLCVIDALIAALALADYDRSTDVLKQTFDVLSIKRF
>Mature_295_residues
PSSPQSSVTETAHLPVENALTRIRSALPQMSKTAAKIAAYVVEHPADVVGMSITDLAALVDASEGSVINFCRSIGLGGFQ
HLKLSLAQEIVQPVHFIHEDLEREDSTETVCRKVFHSGIQALRDSLSVLDPKAMAAAVDIIRAARRVEIYGIGSSAPIAE
DAHYRLLRIGLDARVVIDSHVQAISASRCDKDVAVLTISHSGSTNETVAATRLAHEAGARTIVITNFGRSPIQAYADVVL
FTMARETRFRTEAMTSRIAQLCVIDALIAALALADYDRSTDVLKQTFDVLSIKRF

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=279, Percent_Identity=32.9749103942652, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1788767, Length=260, Percent_Identity=28.8461538461538, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI87082369, Length=257, Percent_Identity=26.4591439688716, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI87082130, Length=273, Percent_Identity=26.7399267399267, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32019; Mature: 31888

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSPQSSVTETAHLPVENALTRIRSALPQMSKTAAKIAAYVVEHPADVVGMSITDLAAL
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHH
VDASEGSVINFCRSIGLGGFQHLKLSLAQEIVQPVHFIHEDLEREDSTETVCRKVFHSGI
HCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QALRDSLSVLDPKAMAAAVDIIRAARRVEIYGIGSSAPIAEDAHYRLLRIGLDARVVIDS
HHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHEEEEECCCEEEEHHH
HVQAISASRCDKDVAVLTISHSGSTNETVAATRLAHEAGARTIVITNFGRSPIQAYADVV
HHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LFTMARETRFRTEAMTSRIAQLCVIDALIAALALADYDRSTDVLKQTFDVLSIKRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSSPQSSVTETAHLPVENALTRIRSALPQMSKTAAKIAAYVVEHPADVVGMSITDLAAL
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHH
VDASEGSVINFCRSIGLGGFQHLKLSLAQEIVQPVHFIHEDLEREDSTETVCRKVFHSGI
HCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QALRDSLSVLDPKAMAAAVDIIRAARRVEIYGIGSSAPIAEDAHYRLLRIGLDARVVIDS
HHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHEEEEECCCEEEEHHH
HVQAISASRCDKDVAVLTISHSGSTNETVAATRLAHEAGARTIVITNFGRSPIQAYADVV
HHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
LFTMARETRFRTEAMTSRIAQLCVIDALIAALALADYDRSTDVLKQTFDVLSIKRF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]