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The map label for this gene is ctaD [H]

Identifier: 87198936

GI number: 87198936

Start: 967462

End: 969150

Strand: Direct

Name: ctaD [H]

Synonym: Saro_0914

Alternate gene names: 87198936

Gene position: 967462-969150 (Clockwise)

Preceding gene: 87198935

Following gene: 87198937

Centisome position: 27.16

GC content: 62.34

Gene sequence:

>1689_bases
ATGGCCACCATACCAGCTAACGAAGGCTTCGATGCGCATCACGATGCGCACGACCACGACCATGATCATCCGGGCTTCTT
CGCCCGGTGGTTCATGTCCACCAACCACAAGGACATCGGTACGATGTACCTGATCTTCGCGATCTTCGCGGGGGTCATCG
GCGGCGCGGTTTCGGGCATGATGCGTGCCGAACTCGCACAGCCGGGCATCCAGTACCTGGGCATGTTCGCCGAATTCCTC
GGCGAGAAGAACCCGAGCTTCGACCAGCAGCTCCACCTGTGGAACGTGCTGATCACCGCGCACGGCCTGATCATGGTGTT
CTTCATGGTCATGCCCGCGATCATCGGCGGCTTCGGCAACTGGTTCGTTCCGATCATGATCGGCGCGCCGGACATGGCGT
TCCCGCGCATGAACAACGTCTCGTTCTGGCTGACCTTCGTCGGCTTCTGCTCGCTGATGTTCTCGGCCTTCGTGCCGGGC
GGCACCGGGCAGGGCGCCGGCACCGGGTGGACGGTCTACGCGCCGCTCTCCACTTCGGGCTCGGTCGGTCCGGCCGTCGA
CTTCGCGATCTTCTCGCTGCACCTTGCGGGCGCGGGTTCGATCCTGGGTGCGATCAACTTCATCACCACCATCTTCAACA
TGCGCGCGCCGGGCATGACCCTGCACAAGATGCCGCTGTTCGTGTGGTCTGTGCTGGTTACCGCGTTCCTGCTGCTGCTG
TCGCTGCCGGTCCTTGCCGCCGCGATCACCATGCTGCTGACCGACCGCAACTTCGGCACGACGTTCTTCGATCCGGCCGG
CGGCGGTGACCCGGTTCTGTACCAGCACCTGTTCTGGTTCTTCGGCCACCCCGAAGTGTACATCATGATCCTGCCGGGCT
TCGGCATCATCAGCCAGATCATCTCGACCTTCAGCCGCAAGCCGGTCTTCGGCTACCTCGGCATGGCCTACGCCATGGTC
GCGATCGGCGTCGTCGGGTTCATCGTGTGGGCTCACCACATGTACACCACCGGCCTCGACGTGAACACGAAGATGTACTT
CACCGCCGCAACCATGGTCATCGCGGTGCCGACCGGCATCAAGATCTTCTCGTGGATCGCGACGATGTGGGGCGGCAGCC
TCGAGTTCAAGTCGCCGATGGTCTGGGCGATCGGCTTCATCTTCCTCTTCACCGTGGGCGGCGTGACGGGCGTCGTGCTG
GCCAACGGCGGCGTGGACGACAACCTGCACGACACCTATTACGTCGTCGCGCACTTCCACTACGTGCTGTCTCTGGGTGC
CGTTACCGCGCTCTTCGCCGGGTTCTACTACTGGTTCCCGAAGATGAGCGGCCGCATGCACTCGGAGTTCCTTGCGCACC
TGCAGTTCTGGATCTTCTTCGTCGGCGTGAACCTGATCTTCTTCCCGATGCACTTCCTCGGGATCCAGGGCATGCCGCGC
CGCTATCCGGACTACGCGCTGGCCTATGCCAAGTGGAACGAAGTGGCCTCGATCGGCTACGCCATCATGGCGGTATCGAT
CGTGATCTTCTTCATCAACATCCTCTACGCATTCCTTGCCGGCAAGAAGGCGGAAGCCAACTACTGGGGCGAAGGTGCGA
CGACGCTGGAATGGACGCTGTCCTCGCCGCCGCCGTTCCACCAGTTCGAGACACTGCCGGTGATCGACGACAAGGCCCAC
GCACACTGA

Upstream 100 bases:

>100_bases
TGCCGTTCCTGCGGCAGCCGCAGCTCCCGCCGAAGCCCCGGCCGCCGACGCTTCCGCAGCGCCTGCCGCCTGACGAATTC
ATCGACAAGGTTTGACCGAG

Downstream 100 bases:

>100_bases
GCCTGACCGTCGGCCCAAGGGCTGAGACGAATGGGCCTCCGGGGAAACCCGGGGGCCTTTTTCGTGTCAGCCCCCGGGCC
GGGCAGACGAGGCGCCATCC

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MATIPANEGFDAHHDAHDHDHDHPGFFARWFMSTNHKDIGTMYLIFAIFAGVIGGAVSGMMRAELAQPGIQYLGMFAEFL
GEKNPSFDQQLHLWNVLITAHGLIMVFFMVMPAIIGGFGNWFVPIMIGAPDMAFPRMNNVSFWLTFVGFCSLMFSAFVPG
GTGQGAGTGWTVYAPLSTSGSVGPAVDFAIFSLHLAGAGSILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLL
SLPVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIISQIISTFSRKPVFGYLGMAYAMV
AIGVVGFIVWAHHMYTTGLDVNTKMYFTAATMVIAVPTGIKIFSWIATMWGGSLEFKSPMVWAIGFIFLFTVGGVTGVVL
ANGGVDDNLHDTYYVVAHFHYVLSLGAVTALFAGFYYWFPKMSGRMHSEFLAHLQFWIFFVGVNLIFFPMHFLGIQGMPR
RYPDYALAYAKWNEVASIGYAIMAVSIVIFFINILYAFLAGKKAEANYWGEGATTLEWTLSSPPPFHQFETLPVIDDKAH
AH

Sequences:

>Translated_562_residues
MATIPANEGFDAHHDAHDHDHDHPGFFARWFMSTNHKDIGTMYLIFAIFAGVIGGAVSGMMRAELAQPGIQYLGMFAEFL
GEKNPSFDQQLHLWNVLITAHGLIMVFFMVMPAIIGGFGNWFVPIMIGAPDMAFPRMNNVSFWLTFVGFCSLMFSAFVPG
GTGQGAGTGWTVYAPLSTSGSVGPAVDFAIFSLHLAGAGSILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLL
SLPVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIISQIISTFSRKPVFGYLGMAYAMV
AIGVVGFIVWAHHMYTTGLDVNTKMYFTAATMVIAVPTGIKIFSWIATMWGGSLEFKSPMVWAIGFIFLFTVGGVTGVVL
ANGGVDDNLHDTYYVVAHFHYVLSLGAVTALFAGFYYWFPKMSGRMHSEFLAHLQFWIFFVGVNLIFFPMHFLGIQGMPR
RYPDYALAYAKWNEVASIGYAIMAVSIVIFFINILYAFLAGKKAEANYWGEGATTLEWTLSSPPPFHQFETLPVIDDKAH
AH
>Mature_561_residues
ATIPANEGFDAHHDAHDHDHDHPGFFARWFMSTNHKDIGTMYLIFAIFAGVIGGAVSGMMRAELAQPGIQYLGMFAEFLG
EKNPSFDQQLHLWNVLITAHGLIMVFFMVMPAIIGGFGNWFVPIMIGAPDMAFPRMNNVSFWLTFVGFCSLMFSAFVPGG
TGQGAGTGWTVYAPLSTSGSVGPAVDFAIFSLHLAGAGSILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLLS
LPVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIISQIISTFSRKPVFGYLGMAYAMVA
IGVVGFIVWAHHMYTTGLDVNTKMYFTAATMVIAVPTGIKIFSWIATMWGGSLEFKSPMVWAIGFIFLFTVGGVTGVVLA
NGGVDDNLHDTYYVVAHFHYVLSLGAVTALFAGFYYWFPKMSGRMHSEFLAHLQFWIFFVGVNLIFFPMHFLGIQGMPRR
YPDYALAYAKWNEVASIGYAIMAVSIVIFFINILYAFLAGKKAEANYWGEGATTLEWTLSSPPPFHQFETLPVIDDKAHA
H

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=527, Percent_Identity=59.5825426944972, Blast_Score=580, Evalue=1e-165,
Organism=Escherichia coli, GI1786634, Length=537, Percent_Identity=41.340782122905, Blast_Score=384, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6226519, Length=545, Percent_Identity=55.9633027522936, Blast_Score=584, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6226524, Length=340, Percent_Identity=59.4117647058824, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6226523, Length=266, Percent_Identity=53.3834586466165, Blast_Score=255, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61951; Mature: 61820

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATIPANEGFDAHHDAHDHDHDHPGFFARWFMSTNHKDIGTMYLIFAIFAGVIGGAVSGM
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
MRAELAQPGIQYLGMFAEFLGEKNPSFDQQLHLWNVLITAHGLIMVFFMVMPAIIGGFGN
HHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WFVPIMIGAPDMAFPRMNNVSFWLTFVGFCSLMFSAFVPGGTGQGAGTGWTVYAPLSTSG
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
SVGPAVDFAIFSLHLAGAGSILGAINFITTIFNMRAPGMTLHKMPLFVWSVLVTAFLLLL
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
SLPVLAAAITMLLTDRNFGTTFFDPAGGGDPVLYQHLFWFFGHPEVYIMILPGFGIISQI
HHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
ISTFSRKPVFGYLGMAYAMVAIGVVGFIVWAHHMYTTGLDVNTKMYFTAATMVIAVPTGI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEECCCH
KIFSWIATMWGGSLEFKSPMVWAIGFIFLFTVGGVTGVVLANGGVDDNLHDTYYVVAHFH
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHH
YVLSLGAVTALFAGFYYWFPKMSGRMHSEFLAHLQFWIFFVGVNLIFFPMHFLGIQGMPR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
RYPDYALAYAKWNEVASIGYAIMAVSIVIFFINILYAFLAGKKAEANYWGEGATTLEWTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEE
SSPPPFHQFETLPVIDDKAHAH
CCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]