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The map label for this gene is exbB [H]

Identifier: 87198415

GI number: 87198415

Start: 427167

End: 427850

Strand: Direct

Name: exbB [H]

Synonym: Saro_0390

Alternate gene names: 87198415

Gene position: 427167-427850 (Clockwise)

Preceding gene: 87198414

Following gene: 87198416

Centisome position: 11.99

GC content: 64.04

Gene sequence:

>684_bases
ATGACAACCGACGCTGTTACCGACTTCTCCCCGATCGCGCTGTTCGCGCAGGCCGACATCGTCGTCAAAGTGATCATGCT
CGGCCTTTTGGCAGCCAGCATCTGGACCTGGGCGATCATCGTTGCCCAGATCCTCAAGAACCGCAGGGCGCACGCGACAA
GCGACCTGTTCGAGGCCGAGATCAGGGAAGCGGGATTTACCGGCGAAAGCAGCAAGCACCTCGCCCGCGATGCTTCTCCT
GCAGCCGCCCTGTTCAAGGCCGCGATGGCTGAATGGAGCAAGTCGGTCCGGGCCAGGGCCAGCCTCGACAAGGACGCGGC
CCGCGAGCGGATCGCCGACGTGCTCGAGGGCGCGATCGAGGGGGAAGTCGATCGCCTGTCCGAACGACTCAACTACCTGG
CGACCATCGGCTCCATCGCGCCCTTCGTCGGGCTGTTCGGGACGGTCTGGGGCATCATGCGCAGCTTCACCTCGATCGCG
GCATCGCAGAACACCTCGCTCTCGGTGGTCGCGCCGGGCATCGCCGAAGCCTTGCTCGCGACAGCCATCGGTCTGTTTGC
TGCGATCCCCGCCGTTATTGCCTACAATCGGTTTGGTCACAGCTTGAACCGCTTTGAAGCGCGGCTGGTACGCTTCGCCC
GATACCTGCGCGGCAATCTCAGCCGCGAACTGGACGCGCTCTGA

Upstream 100 bases:

>100_bases
TCCTCGCACCGGCCTGTTCTGACGCGTTCGAACAGGCACCCCCGGGTGCGCGTCTCTTGCGGGCGCGCACCCTGTCACTG
ATCCAAGGCCAACTGTCCCG

Downstream 100 bases:

>100_bases
TGGCGGTCAACCTTTCGGGCGGTTCGGGGCGCGGGCGCCGGGGCTTCGGCGGCCGCAGCCCCATGTCCGAAATCAACGTG
ACGCCGCTGGTCGATGTCAT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTTDAVTDFSPIALFAQADIVVKVIMLGLLAASIWTWAIIVAQILKNRRAHATSDLFEAEIREAGFTGESSKHLARDASP
AAALFKAAMAEWSKSVRARASLDKDAARERIADVLEGAIEGEVDRLSERLNYLATIGSIAPFVGLFGTVWGIMRSFTSIA
ASQNTSLSVVAPGIAEALLATAIGLFAAIPAVIAYNRFGHSLNRFEARLVRFARYLRGNLSRELDAL

Sequences:

>Translated_227_residues
MTTDAVTDFSPIALFAQADIVVKVIMLGLLAASIWTWAIIVAQILKNRRAHATSDLFEAEIREAGFTGESSKHLARDASP
AAALFKAAMAEWSKSVRARASLDKDAARERIADVLEGAIEGEVDRLSERLNYLATIGSIAPFVGLFGTVWGIMRSFTSIA
ASQNTSLSVVAPGIAEALLATAIGLFAAIPAVIAYNRFGHSLNRFEARLVRFARYLRGNLSRELDAL
>Mature_226_residues
TTDAVTDFSPIALFAQADIVVKVIMLGLLAASIWTWAIIVAQILKNRRAHATSDLFEAEIREAGFTGESSKHLARDASPA
AALFKAAMAEWSKSVRARASLDKDAARERIADVLEGAIEGEVDRLSERLNYLATIGSIAPFVGLFGTVWGIMRSFTSIAA
SQNTSLSVVAPGIAEALLATAIGLFAAIPAVIAYNRFGHSLNRFEARLVRFARYLRGNLSRELDAL

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=232, Percent_Identity=42.6724137931034, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786958, Length=223, Percent_Identity=38.5650224215247, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 24466; Mature: 24335

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDAVTDFSPIALFAQADIVVKVIMLGLLAASIWTWAIIVAQILKNRRAHATSDLFEAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IREAGFTGESSKHLARDASPAAALFKAAMAEWSKSVRARASLDKDAARERIADVLEGAIE
HHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
GEVDRLSERLNYLATIGSIAPFVGLFGTVWGIMRSFTSIAASQNTSLSVVAPGIAEALLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
TAIGLFAAIPAVIAYNRFGHSLNRFEARLVRFARYLRGNLSRELDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTDAVTDFSPIALFAQADIVVKVIMLGLLAASIWTWAIIVAQILKNRRAHATSDLFEAE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IREAGFTGESSKHLARDASPAAALFKAAMAEWSKSVRARASLDKDAARERIADVLEGAIE
HHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
GEVDRLSERLNYLATIGSIAPFVGLFGTVWGIMRSFTSIAASQNTSLSVVAPGIAEALLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHH
TAIGLFAAIPAVIAYNRFGHSLNRFEARLVRFARYLRGNLSRELDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]