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The map label for this gene is cobK [H]

Identifier: 87198362

GI number: 87198362

Start: 359527

End: 360288

Strand: Direct

Name: cobK [H]

Synonym: Saro_0337

Alternate gene names: 87198362

Gene position: 359527-360288 (Clockwise)

Preceding gene: 87198346

Following gene: 87198371

Centisome position: 10.09

GC content: 68.77

Gene sequence:

>762_bases
ATGCCCAACGTCCTCCTGCTGGGCGGCACGACAGAGGCCAGCGCGCTTGCCCGCCTGCTTGGCGCGCGGGGCATTGCGAC
GACGCTCAGCTATGCCGGACGGACCGAAAACCCCCGCGCTCAACCGGTGCCGGTGCGTGTCGGCGGGTTCGGCGGTGTGG
CGGGGCTGGCCGATTATCTGCGCCACCACCGCGTGACTCATCTGGTGGACGCGACCCACCCCTTTGCCGCAACGATGAGC
AGCCATGCCGTGGAGGCGGCCCGCCTGGCCGGAGTGCCTCATGTAGCGCTGACCCGCCGGGCGTGGCAACCGGTCGCCGG
AGACCGCTGGACCCGCGTTGCCAGCATCGACGGTGCGGTGGCAGCGCTGGCCGGGCACTCCCGCCGCGTAATGCTGGCGC
TGGGCCGGATGCATGTGGCAGCCTTCGCTGCCCAGCCGCAGCATCATTATCTGTTGCGCTTTGTCGATGCGCCAGACCAG
CCGCCGGGCTTGCCCCATCACACCCTGATCGTCGATCGCGGGCCGTTCACCGCCACAGGCGACAGCGCATTGATGGAGGC
GCACGCCATCGATCTGGTGGTGTGCAAGAACGCTGGCGGGCAAGGCGCAGAGGCCAAGCTGATCGCCGCACGGGATCTGG
GCCTGCCGGTCCTGATGATTGATCGCCCTGCCGTTCCGGGCCGGGCCGAATGCTATCGCCCGGAAGATGTACTGGTCTGG
CTGGGTCATGACGCCGAACCCAAGGCCGAACGCGACGTGTAG

Upstream 100 bases:

>100_bases
GGCCTGCGCCAGCGCCGTGCGGGCGGCGGCGGAAAGGCCGTCCGGCCCGTCCTCGCCAATGCCGATGATCGTCAACCACG
CTTCAGGAGCCATATCAGCC

Downstream 100 bases:

>100_bases
AGGATCGGACCGAGCTTTCGCCCACTTGTCCGTTCGATGATCCGCGTCAGGCTTGATCCGACGATCACCATGGTCCGCAT
GTCGGCCATGTCTGCACGGG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MPNVLLLGGTTEASALARLLGARGIATTLSYAGRTENPRAQPVPVRVGGFGGVAGLADYLRHHRVTHLVDATHPFAATMS
SHAVEAARLAGVPHVALTRRAWQPVAGDRWTRVASIDGAVAALAGHSRRVMLALGRMHVAAFAAQPQHHYLLRFVDAPDQ
PPGLPHHTLIVDRGPFTATGDSALMEAHAIDLVVCKNAGGQGAEAKLIAARDLGLPVLMIDRPAVPGRAECYRPEDVLVW
LGHDAEPKAERDV

Sequences:

>Translated_253_residues
MPNVLLLGGTTEASALARLLGARGIATTLSYAGRTENPRAQPVPVRVGGFGGVAGLADYLRHHRVTHLVDATHPFAATMS
SHAVEAARLAGVPHVALTRRAWQPVAGDRWTRVASIDGAVAALAGHSRRVMLALGRMHVAAFAAQPQHHYLLRFVDAPDQ
PPGLPHHTLIVDRGPFTATGDSALMEAHAIDLVVCKNAGGQGAEAKLIAARDLGLPVLMIDRPAVPGRAECYRPEDVLVW
LGHDAEPKAERDV
>Mature_252_residues
PNVLLLGGTTEASALARLLGARGIATTLSYAGRTENPRAQPVPVRVGGFGGVAGLADYLRHHRVTHLVDATHPFAATMSS
HAVEAARLAGVPHVALTRRAWQPVAGDRWTRVASIDGAVAALAGHSRRVMLALGRMHVAAFAAQPQHHYLLRFVDAPDQP
PGLPHHTLIVDRGPFTATGDSALMEAHAIDLVVCKNAGGQGAEAKLIAARDLGLPVLMIDRPAVPGRAECYRPEDVLVWL
GHDAEPKAERDV

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26795; Mature: 26664

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNVLLLGGTTEASALARLLGARGIATTLSYAGRTENPRAQPVPVRVGGFGGVAGLADYL
CCCEEEEECCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHH
RHHRVTHLVDATHPFAATMSSHAVEAARLAGVPHVALTRRAWQPVAGDRWTRVASIDGAV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCHH
AALAGHSRRVMLALGRMHVAAFAAQPQHHYLLRFVDAPDQPPGLPHHTLIVDRGPFTATG
HHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCC
DSALMEAHAIDLVVCKNAGGQGAEAKLIAARDLGLPVLMIDRPAVPGRAECYRPEDVLVW
CHHHHHHHEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEE
LGHDAEPKAERDV
ECCCCCCCCCCCC
>Mature Secondary Structure 
PNVLLLGGTTEASALARLLGARGIATTLSYAGRTENPRAQPVPVRVGGFGGVAGLADYL
CCEEEEECCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCHHHHHHHH
RHHRVTHLVDATHPFAATMSSHAVEAARLAGVPHVALTRRAWQPVAGDRWTRVASIDGAV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCHH
AALAGHSRRVMLALGRMHVAAFAAQPQHHYLLRFVDAPDQPPGLPHHTLIVDRGPFTATG
HHHCCCCCEEEEHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCC
DSALMEAHAIDLVVCKNAGGQGAEAKLIAARDLGLPVLMIDRPAVPGRAECYRPEDVLVW
CHHHHHHHEEEEEEEECCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEE
LGHDAEPKAERDV
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]