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The map label for this gene is alsR [H]

Identifier: 87198332

GI number: 87198332

Start: 333031

End: 333927

Strand: Direct

Name: alsR [H]

Synonym: Saro_0307

Alternate gene names: 87198332

Gene position: 333031-333927 (Clockwise)

Preceding gene: 87198331

Following gene: 87198346

Centisome position: 9.35

GC content: 62.43

Gene sequence:

>897_bases
GTGACCATCGAGATACGCCAGCTCCGGTACGCGCTGATGTCAGCAGATCTACGCAGTTTTTCGGGCGCGGCTTCCAGGCT
CAATGTGAAGCAGGCGACGCTCAGTCGCAGTGTCCTGCAACTCGAGGACAGGCTTGGCATCAAACTGTTCGAGCGCACCA
CCCGCGGCGCGGAACCGACTGAAACCGGAAAGGTCTTTCTCGAGACCGCTCGCCGCATCATTACCGATCTGGAAAATCTC
CAGACCACGGCGCGGGCCGTCAGCTACGGCGAGCAAGGCCGCTTCGCCGTAGGGTATTGCTCCTCGCTCATGGCCGGGCA
CCTAAAGGCCGCCTTCTCCGACTACCTCACCCGGTTTCCCGATGTGCAGTTCGACGGAGTCGAAGGCGATCCGGACAAGC
TGTGCAGCGATCTTCGGGCCGGGACGATCGATGTTGCGATCGCGCCGCTCGGCAGCGAAGAACAGGGGATTGCGTCGCGC
CCGGTTTGGTCGGAACGGCTGGTCGCGGCCCTCTACCCCGAGCATCCCTTGCTCGAGGCAAGCCGGATTTACTGGGGCGA
CCTGCGACGCGAGATCTTCGTCGTCCCGCGTAAGGGCATTGGCCAGATGATCCGTAATATGATCACCGCGCGCCTCACCG
GGCAGGGCTACCGTCCCAATATCATCACCCAGGAAACCAGCCTCGAAAGCGTGCTGAGCATGGTCCCGGTCGGCCGGTTC
ATCACCATTGCCACCGAAGCCTCGATGGGTGTCGCATGGCCGGAGCTGCAGTTCCGGGACATCTATGACAATGGCGGCAC
GGCGCGGATCGACTTCGCACTCTACTGGCGCGAGGACAACGAGAACCCGGCGCTGCAGCGCTTCTTCACGATGATCAACG
AGCGTTACCCCGCCTGA

Upstream 100 bases:

>100_bases
ACAAATTGTAATAAATCGTTCTCTTCAATCGATTTCTGTTGCGAGTGCCGCAGAATTCGGCCTCATACTGAAAGTATGTA
GAAGGGAGTGCTGCACGAGC

Downstream 100 bases:

>100_bases
CCGCGCTTCGCCTTGGCAAAGGCGCGGTCGCTGGTGATGAACCGCTCCAGCATGGGCGGGATCAGGCGCTCAACCGTTGG
CGCTCCCGCAGCATCCCCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTIEIRQLRYALMSADLRSFSGAASRLNVKQATLSRSVLQLEDRLGIKLFERTTRGAEPTETGKVFLETARRIITDLENL
QTTARAVSYGEQGRFAVGYCSSLMAGHLKAAFSDYLTRFPDVQFDGVEGDPDKLCSDLRAGTIDVAIAPLGSEEQGIASR
PVWSERLVAALYPEHPLLEASRIYWGDLRREIFVVPRKGIGQMIRNMITARLTGQGYRPNIITQETSLESVLSMVPVGRF
ITIATEASMGVAWPELQFRDIYDNGGTARIDFALYWREDNENPALQRFFTMINERYPA

Sequences:

>Translated_298_residues
MTIEIRQLRYALMSADLRSFSGAASRLNVKQATLSRSVLQLEDRLGIKLFERTTRGAEPTETGKVFLETARRIITDLENL
QTTARAVSYGEQGRFAVGYCSSLMAGHLKAAFSDYLTRFPDVQFDGVEGDPDKLCSDLRAGTIDVAIAPLGSEEQGIASR
PVWSERLVAALYPEHPLLEASRIYWGDLRREIFVVPRKGIGQMIRNMITARLTGQGYRPNIITQETSLESVLSMVPVGRF
ITIATEASMGVAWPELQFRDIYDNGGTARIDFALYWREDNENPALQRFFTMINERYPA
>Mature_297_residues
TIEIRQLRYALMSADLRSFSGAASRLNVKQATLSRSVLQLEDRLGIKLFERTTRGAEPTETGKVFLETARRIITDLENLQ
TTARAVSYGEQGRFAVGYCSSLMAGHLKAAFSDYLTRFPDVQFDGVEGDPDKLCSDLRAGTIDVAIAPLGSEEQGIASRP
VWSERLVAALYPEHPLLEASRIYWGDLRREIFVVPRKGIGQMIRNMITARLTGQGYRPNIITQETSLESVLSMVPVGRFI
TIATEASMGVAWPELQFRDIYDNGGTARIDFALYWREDNENPALQRFFTMINERYPA

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=27.2108843537415, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI2367136, Length=295, Percent_Identity=26.1016949152542, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788887, Length=295, Percent_Identity=25.7627118644068, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1790399, Length=241, Percent_Identity=26.5560165975104, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI157672245, Length=232, Percent_Identity=25.8620689655172, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693105, Length=296, Percent_Identity=22.972972972973, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790262, Length=197, Percent_Identity=26.3959390862944, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789639, Length=143, Percent_Identity=30.0699300699301, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787530, Length=276, Percent_Identity=22.8260869565217, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=186, Percent_Identity=27.4193548387097, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=262, Percent_Identity=24.8091603053435, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788297, Length=166, Percent_Identity=27.1084337349398, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788296, Length=224, Percent_Identity=24.5535714285714, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789204, Length=234, Percent_Identity=24.7863247863248, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33470; Mature: 33338

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIEIRQLRYALMSADLRSFSGAASRLNVKQATLSRSVLQLEDRLGIKLFERTTRGAEPT
CEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
ETGKVFLETARRIITDLENLQTTARAVSYGEQGRFAVGYCSSLMAGHLKAAFSDYLTRFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DVQFDGVEGDPDKLCSDLRAGTIDVAIAPLGSEEQGIASRPVWSERLVAALYPEHPLLEA
CCEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHH
SRIYWGDLRREIFVVPRKGIGQMIRNMITARLTGQGYRPNIITQETSLESVLSMVPVGRF
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCE
ITIATEASMGVAWPELQFRDIYDNGGTARIDFALYWREDNENPALQRFFTMINERYPA
EEEEECCCCCCCCCCCEEEEEECCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIEIRQLRYALMSADLRSFSGAASRLNVKQATLSRSVLQLEDRLGIKLFERTTRGAEPT
EEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
ETGKVFLETARRIITDLENLQTTARAVSYGEQGRFAVGYCSSLMAGHLKAAFSDYLTRFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DVQFDGVEGDPDKLCSDLRAGTIDVAIAPLGSEEQGIASRPVWSERLVAALYPEHPLLEA
CCEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHH
SRIYWGDLRREIFVVPRKGIGQMIRNMITARLTGQGYRPNIITQETSLESVLSMVPVGRF
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHHCCCCE
ITIATEASMGVAWPELQFRDIYDNGGTARIDFALYWREDNENPALQRFFTMINERYPA
EEEEECCCCCCCCCCCEEEEEECCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]