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The map label for this gene is ctrA [H]

Identifier: 87198328

GI number: 87198328

Start: 328963

End: 329664

Strand: Direct

Name: ctrA [H]

Synonym: Saro_0303

Alternate gene names: 87198328

Gene position: 328963-329664 (Clockwise)

Preceding gene: 87198327

Following gene: 87198330

Centisome position: 9.24

GC content: 60.83

Gene sequence:

>702_bases
ATGCGGGTGCTGCTGATTGAAGACGAACCGACCACGGCCAAGGCGATCGAGCTCATGCTCACGACCGAGGGGTTCAACGT
CTATTCGACCGATCTCGGGGAAGAAGGCCTCGATCTCGGGAAGCTGTATGATTACGACATCATCCTTCTCGACCTGAACC
TGCCGGACATGCACGGCTACGACGTGCTGAAGAAGCTCCGGGTCGCCAAGGTGCAGACGCCGGTGCTGATCCTGTCGGGC
ATCTCGGAAATGGACAGCAAGGTCCGCTCGTTCGGCTTCGGCGCGGACGACTACGTGACCAAGCCCTTCCACCGCGAAGA
ACTGATCGCCCGCATCCATGCGGTCGTGCGCCGGTCCAAGGGCCATTCGCAGTCGGTCATCCGCACCGGCAAGCTCTCGG
TCAACCTCGATGCCAAGACGGTCGAGGTCGATGGTGCCCGCGTGCACCTGACCGGCAAGGAATACGCGATGCTGGAACTG
CTCTCGCTGCGCAAGGGCACCACGCTGACCAAGGAAATGTTCCTCAACCATCTCTATGGCGGGATGGACGAGCCGGAACT
CAAGATCATCGACGTGTTCATCTGCAAGCTGCGCAAGAAGCTGGCGCATGCCTGTGGCGGTGAAAACTACATCGAAACCG
TCTGGGGCCGTGGCTACGTGCTGCGCGATCCGGACGACATGAGCGCGATCGAAGCGGCCTGA

Upstream 100 bases:

>100_bases
ATTAACCTTTCATGTTCATTCCTCCTATGGTTAATGGCGGGCAACCCGGATTGAACGCGGGTTAATTGCCACTGGGGACA
TGGCAAAGAGGGGGCAGTCA

Downstream 100 bases:

>100_bases
CCGCACGCGCTGCAATGCCATCCCTGTGACGGCCCGCCGGAAACGGCGGGCCGTTCTGGTTTCAGCTTCCGCTGATCAAC
CGACGCGGTTGAAGTAGGTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: Response regulator SokA [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRVLLIEDEPTTAKAIELMLTTEGFNVYSTDLGEEGLDLGKLYDYDIILLDLNLPDMHGYDVLKKLRVAKVQTPVLILSG
ISEMDSKVRSFGFGADDYVTKPFHREELIARIHAVVRRSKGHSQSVIRTGKLSVNLDAKTVEVDGARVHLTGKEYAMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLAHACGGENYIETVWGRGYVLRDPDDMSAIEAA

Sequences:

>Translated_233_residues
MRVLLIEDEPTTAKAIELMLTTEGFNVYSTDLGEEGLDLGKLYDYDIILLDLNLPDMHGYDVLKKLRVAKVQTPVLILSG
ISEMDSKVRSFGFGADDYVTKPFHREELIARIHAVVRRSKGHSQSVIRTGKLSVNLDAKTVEVDGARVHLTGKEYAMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLAHACGGENYIETVWGRGYVLRDPDDMSAIEAA
>Mature_233_residues
MRVLLIEDEPTTAKAIELMLTTEGFNVYSTDLGEEGLDLGKLYDYDIILLDLNLPDMHGYDVLKKLRVAKVQTPVLILSG
ISEMDSKVRSFGFGADDYVTKPFHREELIARIHAVVRRSKGHSQSVIRTGKLSVNLDAKTVEVDGARVHLTGKEYAMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLAHACGGENYIETVWGRGYVLRDPDDMSAIEAA

Specific function: Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle, including cell division, stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.7142857142857, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.070796460177, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=34.3891402714932, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.579185520362, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=33.7899543378995, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.9559471365639, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=31.2775330396476, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=33.6244541484716, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=31.5315315315315, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.1369863013699, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=32.4324324324324, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=28.6363636363636, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=23.8938053097345, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=30.8411214953271, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=26.25, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790299, Length=161, Percent_Identity=24.8447204968944, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26116; Mature: 26116

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDEPTTAKAIELMLTTEGFNVYSTDLGEEGLDLGKLYDYDIILLDLNLPDMHGY
CEEEEEECCCCHHHEEEEEEEECCCEEEECCCCCCCCCCCCEECCEEEEEEECCCCCCCH
DVLKKLRVAKVQTPVLILSGISEMDSKVRSFGFGADDYVTKPFHREELIARIHAVVRRSK
HHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHCC
GHSQSVIRTGKLSVNLDAKTVEVDGARVHLTGKEYAMLELLSLRKGTTLTKEMFLNHLYG
CCCCHHEEECCEEEEECCEEEEECCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLAHACGGENYIETVWGRGYVLRDPDDMSAIEAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCHHHCCC
>Mature Secondary Structure
MRVLLIEDEPTTAKAIELMLTTEGFNVYSTDLGEEGLDLGKLYDYDIILLDLNLPDMHGY
CEEEEEECCCCHHHEEEEEEEECCCEEEECCCCCCCCCCCCEECCEEEEEEECCCCCCCH
DVLKKLRVAKVQTPVLILSGISEMDSKVRSFGFGADDYVTKPFHREELIARIHAVVRRSK
HHHHHHHHHHHCCCCCEECCHHHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHCC
GHSQSVIRTGKLSVNLDAKTVEVDGARVHLTGKEYAMLELLSLRKGTTLTKEMFLNHLYG
CCCCHHEEECCEEEEECCEEEEECCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLAHACGGENYIETVWGRGYVLRDPDDMSAIEAA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8548829 [H]