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The map label for this gene is yngJ [H]

Identifier: 86751772

GI number: 86751772

Start: 5287410

End: 5288549

Strand: Reverse

Name: yngJ [H]

Synonym: RPB_4674

Alternate gene names: 86751772

Gene position: 5288549-5287410 (Counterclockwise)

Preceding gene: 86751773

Following gene: 86751762

Centisome position: 99.19

GC content: 67.11

Gene sequence:

>1140_bases
ATGGCACTCGTCCTCACCGAAGAACAAACCATGCTGCGCGATTCGGCGCGCGGGCTGATCGGCGACAAGGCTCCGATCGC
GCATTTGCGCAAGCTGCGCGACGAACGCGACGCCACCGGTTTCTCCCGCGAGCTGTGGAAGAGCTTCACCGAGATGGGCT
TCGCCGGCCTCCTGGTGCCGGAAGAGTTCGGCGGCTCCGGGCTCGGCTGCGTCGAGGCCGGCGTGGTGATGGAGGAGATC
GGCCGCAATCTGACGCCGTCGCCGTTTCTGTCGACCGCGGTGCTCGCGGCCTCGGCGCTCGCCCGCGGCGGTTCTGACGC
GCAGAAGAAGGCTTACTTGCCGAAGATCGCCGACGGCTCGCTGATCGCGGCGCTGGCGGTCGACGAAGGCGCCAAGCATC
GGCCGACGAAGATCGCCCTGCAGGCGACCCGCGCCGGCAACGGCTTCAAACTGAAGGGTGCCAAGGCGCTGGTGGTCGAT
GGCCACGTCGCCGATCTGTTGATCGTCGCTGCGCGCAGCGCTGGCAATCCGGGCGATGTCGATGGGCTGACGCTGTTCCT
GGTCGATCCCAAGGCGAAGGGCGTCTCGATCGAGCGCACCGTGATGGTCGATGCCCACAATGCGGCGCGGATCAGCTTGG
ATAATGTCGAGGTCGATACCGATCATGTGCTCGGCGAGGTCGATCGCGGCGGCGCGCTGCTCGAAGGCGTGCTGAACGTG
GGCCGCGCCGCGGTCGCGGCCGAAATGCTCGGCGTCGCCGACGAGGCGTTCGGCCGCACCGTCGCCTACCTGAAAGAGCG
CAAGCAGTTCGGCAAATTGATCGGCGAATTCCAGGCGCTGCAGCACCGCGCCGCGCATCTCTACACCGAGATCGAGATCG
TCCGCGCCGCCGTGCTGAAGGCGCTGCAGGCGATCGACACCGATCCGGAGAATGCCGGTTTCGCCGTCTCGGTCGCCAAG
GCCAAGGCGGGCACGGTGGCGACGCTCGCGGTGCAGGAGGGCGTGCAGATGCACGGCGGCATGGGCATGACCGACCAGTT
CGACGTCGGCCTGTTCATGAAGCGCGCGCGTGTGCTGCAGGAGCTGTTCGGCGACGCGAATTACCACGCCGAGGCGCTGG
CGGCGTGGAAGAAGTATTGA

Upstream 100 bases:

>100_bases
GGGAGTATGGATTCCGGGTCTGAGCCCCGAGGGGCGCATCCCGGAATGACGAACTCTAAAGTTTTGTATCTCATCTGATA
TCTGATCGGGACTTATCACC

Downstream 100 bases:

>100_bases
GGGCATTTCTGGTTTTCGTCGCCCTTCGAGGCGCGCAAGCGCGCGCACCTCAGGGTGACGGAAACCATCGCGATCGCTTC
ATCACCACACGCCCATCACC

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MALVLTEEQTMLRDSARGLIGDKAPIAHLRKLRDERDATGFSRELWKSFTEMGFAGLLVPEEFGGSGLGCVEAGVVMEEI
GRNLTPSPFLSTAVLAASALARGGSDAQKKAYLPKIADGSLIAALAVDEGAKHRPTKIALQATRAGNGFKLKGAKALVVD
GHVADLLIVAARSAGNPGDVDGLTLFLVDPKAKGVSIERTVMVDAHNAARISLDNVEVDTDHVLGEVDRGGALLEGVLNV
GRAAVAAEMLGVADEAFGRTVAYLKERKQFGKLIGEFQALQHRAAHLYTEIEIVRAAVLKALQAIDTDPENAGFAVSVAK
AKAGTVATLAVQEGVQMHGGMGMTDQFDVGLFMKRARVLQELFGDANYHAEALAAWKKY

Sequences:

>Translated_379_residues
MALVLTEEQTMLRDSARGLIGDKAPIAHLRKLRDERDATGFSRELWKSFTEMGFAGLLVPEEFGGSGLGCVEAGVVMEEI
GRNLTPSPFLSTAVLAASALARGGSDAQKKAYLPKIADGSLIAALAVDEGAKHRPTKIALQATRAGNGFKLKGAKALVVD
GHVADLLIVAARSAGNPGDVDGLTLFLVDPKAKGVSIERTVMVDAHNAARISLDNVEVDTDHVLGEVDRGGALLEGVLNV
GRAAVAAEMLGVADEAFGRTVAYLKERKQFGKLIGEFQALQHRAAHLYTEIEIVRAAVLKALQAIDTDPENAGFAVSVAK
AKAGTVATLAVQEGVQMHGGMGMTDQFDVGLFMKRARVLQELFGDANYHAEALAAWKKY
>Mature_378_residues
ALVLTEEQTMLRDSARGLIGDKAPIAHLRKLRDERDATGFSRELWKSFTEMGFAGLLVPEEFGGSGLGCVEAGVVMEEIG
RNLTPSPFLSTAVLAASALARGGSDAQKKAYLPKIADGSLIAALAVDEGAKHRPTKIALQATRAGNGFKLKGAKALVVDG
HVADLLIVAARSAGNPGDVDGLTLFLVDPKAKGVSIERTVMVDAHNAARISLDNVEVDTDHVLGEVDRGGALLEGVLNVG
RAAVAAEMLGVADEAFGRTVAYLKERKQFGKLIGEFQALQHRAAHLYTEIEIVRAAVLKALQAIDTDPENAGFAVSVAKA
KAGTVATLAVQEGVQMHGGMGMTDQFDVGLFMKRARVLQELFGDANYHAEALAAWKKY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=369, Percent_Identity=31.1653116531165, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=30.9090909090909, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI4501859, Length=360, Percent_Identity=27.5, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI4501857, Length=370, Percent_Identity=27.2972972972973, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI187960098, Length=372, Percent_Identity=28.494623655914, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4557231, Length=372, Percent_Identity=28.494623655914, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4557235, Length=330, Percent_Identity=26.3636363636364, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI76496475, Length=330, Percent_Identity=26.3636363636364, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI7656849, Length=330, Percent_Identity=24.8484848484848, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI21361497, Length=332, Percent_Identity=25, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4557233, Length=319, Percent_Identity=26.6457680250784, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI7669494, Length=358, Percent_Identity=26.8156424581006, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI4503943, Length=358, Percent_Identity=26.8156424581006, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI87081958, Length=363, Percent_Identity=28.099173553719, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786223, Length=361, Percent_Identity=24.6537396121884, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=380, Percent_Identity=29.4736842105263, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17508101, Length=351, Percent_Identity=29.9145299145299, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17538396, Length=369, Percent_Identity=27.3712737127371, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI71990804, Length=256, Percent_Identity=30.46875, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17534899, Length=335, Percent_Identity=27.1641791044776, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17569725, Length=368, Percent_Identity=26.3586956521739, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=30.9012875536481, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71985184, Length=347, Percent_Identity=25.0720461095101, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=320, Percent_Identity=25.9375, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=26.6490765171504, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=372, Percent_Identity=25.8064516129032, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=278, Percent_Identity=25.8992805755396, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71982178, Length=251, Percent_Identity=29.4820717131474, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=309, Percent_Identity=24.5954692556634, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=321, Percent_Identity=25.5451713395639, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562446, Length=369, Percent_Identity=26.0162601626016, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355753, Length=367, Percent_Identity=28.3378746594005, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24666513, Length=363, Percent_Identity=29.2011019283747, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=27.1739130434783, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24660351, Length=368, Percent_Identity=26.9021739130435, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646207, Length=366, Percent_Identity=27.3224043715847, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI281363737, Length=336, Percent_Identity=25.8928571428571, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920834, Length=360, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 40080; Mature: 39948

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVLTEEQTMLRDSARGLIGDKAPIAHLRKLRDERDATGFSRELWKSFTEMGFAGLLVP
CEEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECC
EEFGGSGLGCVEAGVVMEEIGRNLTPSPFLSTAVLAASALARGGSDAQKKAYLPKIADGS
HHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC
LIAALAVDEGAKHRPTKIALQATRAGNGFKLKGAKALVVDGHVADLLIVAARSAGNPGDV
EEEEEEECCCCCCCCCEEEEEEEECCCCEEECCCEEEEECCHHHHHHHHHHHCCCCCCCC
DGLTLFLVDPKAKGVSIERTVMVDAHNAARISLDNVEVDTDHVLGEVDRGGALLEGVLNV
CCEEEEEECCCCCCCEEEEEEEEECCCCEEEEECCEEECHHHHHCCCCCCHHHHHHHHHH
GRAAVAAEMLGVADEAFGRTVAYLKERKQFGKLIGEFQALQHRAAHLYTEIEIVRAAVLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQAIDTDPENAGFAVSVAKAKAGTVATLAVQEGVQMHGGMGMTDQFDVGLFMKRARVLQ
HHHHHCCCCCCCCEEEEEECCCCCCEEEHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHH
ELFGDANYHAEALAAWKKY
HHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
ALVLTEEQTMLRDSARGLIGDKAPIAHLRKLRDERDATGFSRELWKSFTEMGFAGLLVP
EEEEECHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECC
EEFGGSGLGCVEAGVVMEEIGRNLTPSPFLSTAVLAASALARGGSDAQKKAYLPKIADGS
HHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCC
LIAALAVDEGAKHRPTKIALQATRAGNGFKLKGAKALVVDGHVADLLIVAARSAGNPGDV
EEEEEEECCCCCCCCCEEEEEEEECCCCEEECCCEEEEECCHHHHHHHHHHHCCCCCCCC
DGLTLFLVDPKAKGVSIERTVMVDAHNAARISLDNVEVDTDHVLGEVDRGGALLEGVLNV
CCEEEEEECCCCCCCEEEEEEEEECCCCEEEEECCEEECHHHHHCCCCCCHHHHHHHHHH
GRAAVAAEMLGVADEAFGRTVAYLKERKQFGKLIGEFQALQHRAAHLYTEIEIVRAAVLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALQAIDTDPENAGFAVSVAKAKAGTVATLAVQEGVQMHGGMGMTDQFDVGLFMKRARVLQ
HHHHHCCCCCCCCEEEEEECCCCCCEEEHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHH
ELFGDANYHAEALAAWKKY
HHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]