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The map label for this gene is yngJ [H]

Identifier: 86751773

GI number: 86751773

Start: 5288717

End: 5289910

Strand: Reverse

Name: yngJ [H]

Synonym: RPB_4675

Alternate gene names: 86751773

Gene position: 5289910-5288717 (Counterclockwise)

Preceding gene: 86751776

Following gene: 86751772

Centisome position: 99.22

GC content: 66.58

Gene sequence:

>1194_bases
ATGCCAGACGCACAGAATCTCGATCAATTCCGCCGCGACACCCGCGCCTGGCTGGAGGCCAATTGCCCGGCCGAGATGCG
CACGCCGATGCAGGGCGACGAGGACAATTTCTGGGGCGGGCGCAACGCCAAATTCGCGTCCGACGCGCAGAAGGTCTGGT
TCGAGCGGATGCGCGACAAGGGCTGGACCGTGCCGGACTGGCCGACCCAATATGGTGGCGGCGGGCTCGATCCCGCGCAA
GCCAAGGTGCTGCGCGAAGAGATGGCGGCGATCGGCGCGCGTTCGCCGCTGTCGAGCTTCGGCATCTGGATGCTCGGGCC
GGCGCTGCTGAAATACGGCAACGAACAGCAGAAGGCGGAGCATCTGCCGAAAATTGCGCGCGGCGAAATTCGCTGGTGCC
AGGGCTATTCCGAGCCGAACGCCGGCTCCGACCTCGCCTCGCTGCAGACCCGCGCCGTGCCCGACGGCGACGACTTCATC
ATCAACGGTTCGAAGATCTGGACCTCTTACGCCAACTACGCCGACTGGATCTTCTGCCTGGTGCGGACCGATGCCAGCGC
CAAGAAGCACGACGGCATCAGCTTCATCCTGTTCGACATGGCCTCGCCCGGCGTGACGACCAAGCCGATCCTGCTGATCT
CCGGCAAGTCGCCGTTCTGCGAGACCTTCTTCGACAACGTCCGAGTACCGCAATCGCACGTGGTCGGCACTGTCAACCGT
GGCTGGGATGTGGCGAAGTATCTGCTGCAGCACGAGCGCGCGATGATCTCCGGCATGGGCGGCCGCGACGGCGGTCGGCC
GCTCGGCCAGGTCGCGGCGGATTCGCTGGGCACCGACGATCAAGGCCGGCTCGACGATCCGATGCTGCGCGGCCAGATCG
CTGCGTTCGATGTCGACGAGGCGGCGCTGGCCTGCGCGGCCGAGCGCGCGGTCGATCTGGCCAAGGCCGGTCAATTGCAC
CCGGCATTCTCGTCGGCGATGAAGTACTACGGCACCGAGCTGAACAAGCGCCGCCACGAGATCCTGATGTCGGCCGGCGG
CATCGACGCGCTGGAGTGGGAAAGCGAGCGCAGCCACGACGGCGCCCGCGCCCGCGCCTGGCTGCGTACCAAGGCGAACT
CGATCGAGGGCGGCACCAGCGAAGTGATGCTCGGCATCGTCGCCAAGCGCATCCTCGATCTGCCGGGGGCGTAA

Upstream 100 bases:

>100_bases
GGGCTGCGATCCAGATGTTGAATTTCGCCCCGCGCGGGCTAAGGTCGCGGCCAACAAGAGCAACAGATCGCGCTTGCGAT
CGCCGGATGGAAACACGCCG

Downstream 100 bases:

>100_bases
GTACACCTCTCCACGTCGTTCCGGGGCGCGAGCGCCGCTCGCGAACCCGGAATCCATCACCACCGCAGGGAGTATGGATT
CCGGGTCTGAGCCCCGAGGG

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPDAQNLDQFRRDTRAWLEANCPAEMRTPMQGDEDNFWGGRNAKFASDAQKVWFERMRDKGWTVPDWPTQYGGGGLDPAQ
AKVLREEMAAIGARSPLSSFGIWMLGPALLKYGNEQQKAEHLPKIARGEIRWCQGYSEPNAGSDLASLQTRAVPDGDDFI
INGSKIWTSYANYADWIFCLVRTDASAKKHDGISFILFDMASPGVTTKPILLISGKSPFCETFFDNVRVPQSHVVGTVNR
GWDVAKYLLQHERAMISGMGGRDGGRPLGQVAADSLGTDDQGRLDDPMLRGQIAAFDVDEAALACAAERAVDLAKAGQLH
PAFSSAMKYYGTELNKRRHEILMSAGGIDALEWESERSHDGARARAWLRTKANSIEGGTSEVMLGIVAKRILDLPGA

Sequences:

>Translated_397_residues
MPDAQNLDQFRRDTRAWLEANCPAEMRTPMQGDEDNFWGGRNAKFASDAQKVWFERMRDKGWTVPDWPTQYGGGGLDPAQ
AKVLREEMAAIGARSPLSSFGIWMLGPALLKYGNEQQKAEHLPKIARGEIRWCQGYSEPNAGSDLASLQTRAVPDGDDFI
INGSKIWTSYANYADWIFCLVRTDASAKKHDGISFILFDMASPGVTTKPILLISGKSPFCETFFDNVRVPQSHVVGTVNR
GWDVAKYLLQHERAMISGMGGRDGGRPLGQVAADSLGTDDQGRLDDPMLRGQIAAFDVDEAALACAAERAVDLAKAGQLH
PAFSSAMKYYGTELNKRRHEILMSAGGIDALEWESERSHDGARARAWLRTKANSIEGGTSEVMLGIVAKRILDLPGA
>Mature_396_residues
PDAQNLDQFRRDTRAWLEANCPAEMRTPMQGDEDNFWGGRNAKFASDAQKVWFERMRDKGWTVPDWPTQYGGGGLDPAQA
KVLREEMAAIGARSPLSSFGIWMLGPALLKYGNEQQKAEHLPKIARGEIRWCQGYSEPNAGSDLASLQTRAVPDGDDFII
NGSKIWTSYANYADWIFCLVRTDASAKKHDGISFILFDMASPGVTTKPILLISGKSPFCETFFDNVRVPQSHVVGTVNRG
WDVAKYLLQHERAMISGMGGRDGGRPLGQVAADSLGTDDQGRLDDPMLRGQIAAFDVDEAALACAAERAVDLAKAGQLHP
AFSSAMKYYGTELNKRRHEILMSAGGIDALEWESERSHDGARARAWLRTKANSIEGGTSEVMLGIVAKRILDLPGA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958414, Length=214, Percent_Identity=31.3084112149533, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226958412, Length=196, Percent_Identity=32.6530612244898, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=25.5434782608696, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4501857, Length=359, Percent_Identity=25.3481894150418, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4557235, Length=202, Percent_Identity=32.1782178217822, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI76496475, Length=202, Percent_Identity=32.1782178217822, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4557233, Length=363, Percent_Identity=26.4462809917355, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI21361497, Length=208, Percent_Identity=30.2884615384615, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4557231, Length=216, Percent_Identity=30.0925925925926, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI187960098, Length=216, Percent_Identity=30.0925925925926, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI7656849, Length=342, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI7669494, Length=169, Percent_Identity=27.810650887574, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4503943, Length=169, Percent_Identity=27.810650887574, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1786223, Length=151, Percent_Identity=27.8145695364238, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=230, Percent_Identity=30, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=211, Percent_Identity=31.2796208530806, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=267, Percent_Identity=30.7116104868914, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=241, Percent_Identity=31.1203319502075, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=211, Percent_Identity=30.3317535545024, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=357, Percent_Identity=25.7703081232493, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=214, Percent_Identity=30.3738317757009, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=210, Percent_Identity=30, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=195, Percent_Identity=32.3076923076923, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=195, Percent_Identity=32.3076923076923, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985184, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=213, Percent_Identity=28.6384976525822, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=190, Percent_Identity=28.9473684210526, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666513, Length=361, Percent_Identity=27.7008310249307, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356377, Length=233, Percent_Identity=30.4721030042918, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363737, Length=214, Percent_Identity=29.9065420560748, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355753, Length=153, Percent_Identity=34.640522875817, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24660351, Length=216, Percent_Identity=30.5555555555556, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646207, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI19920834, Length=180, Percent_Identity=32.7777777777778, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43597; Mature: 43465

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAQNLDQFRRDTRAWLEANCPAEMRTPMQGDEDNFWGGRNAKFASDAQKVWFERMRDK
CCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GWTVPDWPTQYGGGGLDPAQAKVLREEMAAIGARSPLSSFGIWMLGPALLKYGNEQQKAE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCHHHHHH
HLPKIARGEIRWCQGYSEPNAGSDLASLQTRAVPDGDDFIINGSKIWTSYANYADWIFCL
HCCHHHCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHEEEE
VRTDASAKKHDGISFILFDMASPGVTTKPILLISGKSPFCETFFDNVRVPQSHVVGTVNR
EECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHHHEECCCC
GWDVAKYLLQHERAMISGMGGRDGGRPLGQVAADSLGTDDQGRLDDPMLRGQIAAFDVDE
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEECCHH
AALACAAERAVDLAKAGQLHPAFSSAMKYYGTELNKRRHEILMSAGGIDALEWESERSHD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GARARAWLRTKANSIEGGTSEVMLGIVAKRILDLPGA
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PDAQNLDQFRRDTRAWLEANCPAEMRTPMQGDEDNFWGGRNAKFASDAQKVWFERMRDK
CCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GWTVPDWPTQYGGGGLDPAQAKVLREEMAAIGARSPLSSFGIWMLGPALLKYGNEQQKAE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCHHHHHH
HLPKIARGEIRWCQGYSEPNAGSDLASLQTRAVPDGDDFIINGSKIWTSYANYADWIFCL
HCCHHHCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHEEEE
VRTDASAKKHDGISFILFDMASPGVTTKPILLISGKSPFCETFFDNVRVPQSHVVGTVNR
EECCCCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHHHEECCCC
GWDVAKYLLQHERAMISGMGGRDGGRPLGQVAADSLGTDDQGRLDDPMLRGQIAAFDVDE
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEECCHH
AALACAAERAVDLAKAGQLHPAFSSAMKYYGTELNKRRHEILMSAGGIDALEWESERSHD
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GARARAWLRTKANSIEGGTSEVMLGIVAKRILDLPGA
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]