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The map label for this gene is mgtC [H]

Identifier: 86751652

GI number: 86751652

Start: 5148311

End: 5149033

Strand: Reverse

Name: mgtC [H]

Synonym: RPB_4554

Alternate gene names: 86751652

Gene position: 5149033-5148311 (Counterclockwise)

Preceding gene: 86751653

Following gene: 86751651

Centisome position: 96.57

GC content: 66.67

Gene sequence:

>723_bases
ATGCGCTTCCTCGCCACCTTCCAGACCCTCGACTTCCTCGACACGCTGATCAGCCTGGGCGCAGCCTTCGTGCTCGGCAT
GCTGATCGGCGCCGAGCGGCAATATCGGACCCGTGCGGCGGGGCTGCGCACCAACGTGCTGGTGGCGGTGGGCGCCGCCG
CCTTCGTCGATCTCGCCATGCACCTCAAGGGCGTCGACGGCGCGGTGCATGTGATCGCCTATGTGGTGTCCGGCATCGGC
TTCCTCGGCGCCGGCGTGATCATGAAAGAGGGCATGAATGTCCGCGGCCTCAACACCGCGGCGACGCTGTGGAGCTCGGC
CGCGGTCGGCTGCTGCGCCGGCGCCGACATGGTGGCGCAGGCGGTGGCGCTGACCGTGTTCGTGATCGCCGGCAACACGC
TGCTGCGGCCGCTGGTCAATGCCATCAACCGCATCCCGTTCGACGAGCGCTCCTCGGAGGCGACCTATTCGGTGCGGCTC
ACCGCCGGCAGCGCCTCCGCCGATCAGCTCCGCGATCAACTGGAAGAACGGCTCGAAGCGGCCGATTACCCGGTCGCCGA
GATCGAGGTCGAAACCTCCGAACACGCCGACGACAAGGTCGAAATCGTCGCGACGCTGGTGTCGACCTCGATCGAACCGA
GGGAACTCGACATCGTCGTCGCCGACATGGAGAAACGCCCGGGCGTCGATTACGCGACCTGGGAAACCAGCACTAAGGAT
TGA

Upstream 100 bases:

>100_bases
GAATGCGAGCGGCAGTCTGCTGGCATTCGCCGACGAGGAGGGTGCAGCGGGACTGCTGACGCTGTAAGAGGAAGCCGGTT
CCCGACCGGGCGGTTTTCTC

Downstream 100 bases:

>100_bases
TTCACGTCGTCACTCAAATACGACCGAACGGGAACCCGTGCCGCACGCGGGAACGGAACGTTGCCATCCCGCATCCGTTG
TTTCGCCAGGCAAGGGATGA

Product: MgtC/SapB transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRFLATFQTLDFLDTLISLGAAFVLGMLIGAERQYRTRAAGLRTNVLVAVGAAAFVDLAMHLKGVDGAVHVIAYVVSGIG
FLGAGVIMKEGMNVRGLNTAATLWSSAAVGCCAGADMVAQAVALTVFVIAGNTLLRPLVNAINRIPFDERSSEATYSVRL
TAGSASADQLRDQLEERLEAADYPVAEIEVETSEHADDKVEIVATLVSTSIEPRELDIVVADMEKRPGVDYATWETSTKD

Sequences:

>Translated_240_residues
MRFLATFQTLDFLDTLISLGAAFVLGMLIGAERQYRTRAAGLRTNVLVAVGAAAFVDLAMHLKGVDGAVHVIAYVVSGIG
FLGAGVIMKEGMNVRGLNTAATLWSSAAVGCCAGADMVAQAVALTVFVIAGNTLLRPLVNAINRIPFDERSSEATYSVRL
TAGSASADQLRDQLEERLEAADYPVAEIEVETSEHADDKVEIVATLVSTSIEPRELDIVVADMEKRPGVDYATWETSTKD
>Mature_240_residues
MRFLATFQTLDFLDTLISLGAAFVLGMLIGAERQYRTRAAGLRTNVLVAVGAAAFVDLAMHLKGVDGAVHVIAYVVSGIG
FLGAGVIMKEGMNVRGLNTAATLWSSAAVGCCAGADMVAQAVALTVFVIAGNTLLRPLVNAINRIPFDERSSEATYSVRL
TAGSASADQLRDQLEERLEAADYPVAEIEVETSEHADDKVEIVATLVSTSIEPRELDIVVADMEKRPGVDYATWETSTKD

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=191, Percent_Identity=29.3193717277487, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25537; Mature: 25537

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLATFQTLDFLDTLISLGAAFVLGMLIGAERQYRTRAAGLRTNVLVAVGAAAFVDLAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HLKGVDGAVHVIAYVVSGIGFLGAGVIMKEGMNVRGLNTAATLWSSAAVGCCAGADMVAQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
AVALTVFVIAGNTLLRPLVNAINRIPFDERSSEATYSVRLTAGSASADQLRDQLEERLEA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
ADYPVAEIEVETSEHADDKVEIVATLVSTSIEPRELDIVVADMEKRPGVDYATWETSTKD
CCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MRFLATFQTLDFLDTLISLGAAFVLGMLIGAERQYRTRAAGLRTNVLVAVGAAAFVDLAM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
HLKGVDGAVHVIAYVVSGIGFLGAGVIMKEGMNVRGLNTAATLWSSAAVGCCAGADMVAQ
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
AVALTVFVIAGNTLLRPLVNAINRIPFDERSSEATYSVRLTAGSASADQLRDQLEERLEA
HHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHH
ADYPVAEIEVETSEHADDKVEIVATLVSTSIEPRELDIVVADMEKRPGVDYATWETSTKD
CCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA