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The map label for this gene is feaR [H]

Identifier: 86750549

GI number: 86750549

Start: 3941868

End: 3942926

Strand: Direct

Name: feaR [H]

Synonym: RPB_3438

Alternate gene names: 86750549

Gene position: 3941868-3942926 (Clockwise)

Preceding gene: 86750547

Following gene: 86750550

Centisome position: 73.93

GC content: 68.37

Gene sequence:

>1059_bases
ATGGCGTCCCTTCCCCGACTGTTCTACGTGACTTCCAGCCTGGACGAGGCGACCGCCCTGGCGACCTGGAGTGCGGTGAT
CTCGCCGCTGTTCGAACCGCGCCCCTGCGGCCCGAGCAAGAAGACACCGACCGGCTCGGCCTATGGCATCATCATTGGCG
ACCTGATCATCGCCAAGGTCGCCTTCAACGCGCAGGACTTCGTCCGCGACGAGCCACGCATCGCGGCGACGCCGGATCAC
CTGCTGCTGCATCTCTACGTAACCGGCGGGTTCAACGGTGTGGTCACCCGGCAGCAGACGGCGATCGGCCCCGGCAAGGT
CGCGCTGATCGATCTGGCCCATCCGATCGCCACGCGCGCTTTCGCCTCCAGCACGGTGTGCCTGATCGTTCCGCGCAAGC
TGCTCGGCGGCCTGCCGCTCGACACGCTGAAGCCGAGGCTCGATCCGCTCCGGAACGATCTGCTCGCGGCGCATCTGCGA
TCGCTTCAGGAACGCAGCGCGCAATTGACCGAGACGGACGTGGCCGACACGGTGGCCGACACCGTGGGTTTTCTGAGACG
GCTGCTCGCCCCCGCCCAGGATGAATCGCCAGCCGCCGAGCAGCGAACCGACGAGACCATCCTGGCGCTTCTGGAAGCGC
TGATCCGCGACAATCTCGCTTCGCCCGATCTGTCGCCGGATTGGCTGGCACAGCGACTGGATGTCTCGCGCGCGTCGCTG
TATCGGCTGTTTGCCGACCGCGGCGGCATCATGCGCTACGTCCAGGAACGGCGGCTGCTCGCGGTCCAGGCGGCGCTGAG
CGATCCGATCGAAACGCGCCGCTTGTCCCGCCTGGCGTCCGATCTCGGCTTCAAGAGCGAGGCGCATTTCAGCCGGAGCT
TTCGCGCCCGCTTCGGCGTCACCGCCAGCGCCTTTCGCAAGGCGCAACTCGACGCCTCCGCGGCGATCCAGCTCACCAGC
CCGGCGGTGGTGCAACAATGGTGGACGGCGGTCGCTCGGAGCCCGCCGGCCCGCGGCCTGGCCCCGGCCGACGAGCGGGG
CGCGGTCCTTCCGCTGTAG

Upstream 100 bases:

>100_bases
CGTGTCTCGGGAGGGATTGCGGTAGAACCATCGCCCGCATCCGGACGCGGCGTTCCCCGAGCCGCCCGGAGACGATATCG
GCAGTATCAGATCGCGCGTG

Downstream 100 bases:

>100_bases
CCGAATTCCGTATTGCGCGGCTGCGTCGGCCGCGTGTATGAGCCGATCATTCGTCCGCGGAGGGATCGGCGTTGAATTTC
AGTGCCGTCTTTCATCAGTT

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MASLPRLFYVTSSLDEATALATWSAVISPLFEPRPCGPSKKTPTGSAYGIIIGDLIIAKVAFNAQDFVRDEPRIAATPDH
LLLHLYVTGGFNGVVTRQQTAIGPGKVALIDLAHPIATRAFASSTVCLIVPRKLLGGLPLDTLKPRLDPLRNDLLAAHLR
SLQERSAQLTETDVADTVADTVGFLRRLLAPAQDESPAAEQRTDETILALLEALIRDNLASPDLSPDWLAQRLDVSRASL
YRLFADRGGIMRYVQERRLLAVQAALSDPIETRRLSRLASDLGFKSEAHFSRSFRARFGVTASAFRKAQLDASAAIQLTS
PAVVQQWWTAVARSPPARGLAPADERGAVLPL

Sequences:

>Translated_352_residues
MASLPRLFYVTSSLDEATALATWSAVISPLFEPRPCGPSKKTPTGSAYGIIIGDLIIAKVAFNAQDFVRDEPRIAATPDH
LLLHLYVTGGFNGVVTRQQTAIGPGKVALIDLAHPIATRAFASSTVCLIVPRKLLGGLPLDTLKPRLDPLRNDLLAAHLR
SLQERSAQLTETDVADTVADTVGFLRRLLAPAQDESPAAEQRTDETILALLEALIRDNLASPDLSPDWLAQRLDVSRASL
YRLFADRGGIMRYVQERRLLAVQAALSDPIETRRLSRLASDLGFKSEAHFSRSFRARFGVTASAFRKAQLDASAAIQLTS
PAVVQQWWTAVARSPPARGLAPADERGAVLPL
>Mature_351_residues
ASLPRLFYVTSSLDEATALATWSAVISPLFEPRPCGPSKKTPTGSAYGIIIGDLIIAKVAFNAQDFVRDEPRIAATPDHL
LLHLYVTGGFNGVVTRQQTAIGPGKVALIDLAHPIATRAFASSTVCLIVPRKLLGGLPLDTLKPRLDPLRNDLLAAHLRS
LQERSAQLTETDVADTVADTVGFLRRLLAPAQDESPAAEQRTDETILALLEALIRDNLASPDLSPDWLAQRLDVSRASLY
RLFADRGGIMRYVQERRLLAVQAALSDPIETRRLSRLASDLGFKSEAHFSRSFRARFGVTASAFRKAQLDASAAIQLTSP
AVVQQWWTAVARSPPARGLAPADERGAVLPL

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=220, Percent_Identity=30, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38154; Mature: 38023

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLPRLFYVTSSLDEATALATWSAVISPLFEPRPCGPSKKTPTGSAYGIIIGDLIIAKV
CCCCCCHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AFNAQDFVRDEPRIAATPDHLLLHLYVTGGFNGVVTRQQTAIGPGKVALIDLAHPIATRA
HCCHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEECCHHCCCCCCEEEEEHHHHHHHHH
FASSTVCLIVPRKLLGGLPLDTLKPRLDPLRNDLLAAHLRSLQERSAQLTETDVADTVAD
HHCCCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVGFLRRLLAPAQDESPAAEQRTDETILALLEALIRDNLASPDLSPDWLAQRLDVSRASL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
YRLFADRGGIMRYVQERRLLAVQAALSDPIETRRLSRLASDLGFKSEAHFSRSFRARFGV
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
TASAFRKAQLDASAAIQLTSPAVVQQWWTAVARSPPARGLAPADERGAVLPL
CHHHHHHHHCCCHHEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASLPRLFYVTSSLDEATALATWSAVISPLFEPRPCGPSKKTPTGSAYGIIIGDLIIAKV
CCCCCHHEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AFNAQDFVRDEPRIAATPDHLLLHLYVTGGFNGVVTRQQTAIGPGKVALIDLAHPIATRA
HCCHHHHHCCCCCCCCCCCCEEEEEEEECCCCCEEECCHHCCCCCCEEEEEHHHHHHHHH
FASSTVCLIVPRKLLGGLPLDTLKPRLDPLRNDLLAAHLRSLQERSAQLTETDVADTVAD
HHCCCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVGFLRRLLAPAQDESPAAEQRTDETILALLEALIRDNLASPDLSPDWLAQRLDVSRASL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
YRLFADRGGIMRYVQERRLLAVQAALSDPIETRRLSRLASDLGFKSEAHFSRSFRARFGV
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
TASAFRKAQLDASAAIQLTSPAVVQQWWTAVARSPPARGLAPADERGAVLPL
CHHHHHHHHCCCHHEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]