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The map label for this gene is frc [H]

Identifier: 86750538

GI number: 86750538

Start: 3924796

End: 3926073

Strand: Direct

Name: frc [H]

Synonym: RPB_3427

Alternate gene names: 86750538

Gene position: 3924796-3926073 (Clockwise)

Preceding gene: 86750537

Following gene: 86750539

Centisome position: 73.61

GC content: 65.1

Gene sequence:

>1278_bases
ATGACCAAGGCGCTCGACGGCGTTCGCATTCTCGATTTCACCCACGTCCAGTCCGGCCCGACCTGCACCCAGTTGCTGGC
GTGGTTCGGCGCCGACGTCATCAAGGTCGAGCGTCCCGGCACCGGCGACATCACCCGCGGGCAGTTGCAGGACATCCCGA
AGGTGGACAGCCTGTATTTCACCATGCTGAACCACAACAAGCGCTCGATCACGCTCGACACCAAGAACCCCAAGGGCAAG
GAGGTGCTGACCGCGCTGATCCGCTCCTGCGACGTGCTGGTGGAGAATTTCGGCCCCGGCGTGCTCGATCGCATGGGCTT
CACCTGGGACAAGATCCAGGAGATCAACCCGCGGATGATCGTCGCCTCGATCAAGGGTTTCGGCCCGGGTCCCTATGAAG
ACTGCAAGGTCTACGAGAACGTCGCGCAATGCACCGGCGGCGCCGCCTCGACCACCGGCTTCCGCGACGGCCCGCCGCTG
GTCACCGGCGCACAGATCGGCGACTCGGGCACCGGGCTGCATCTCGCGCTCGGCATCGTCACCGCGCTGTATCAGCGCCA
TCACACCGGCCGCGGCCAGCGCGTCACCGCCGCGATGCAGGACGGCGTGCTCAATTTGTCGCGCGTCAAGCTGCGCGATC
AGCAGCGCCTCGCCCACGGCCCGCTCAAGGAATACAGCCAGTTCGGCGAAGGCATTCCGTTCGGCGACGCGGTGCCGCGC
GCCGGCAATGATTCCGGCGGCGGCCAGCCCGGCCGCATCCTGAAATGCAAGGGCTGGGAGACCGATCCCAACGCCTACAT
CTACTTCATCGCGCAGGCCCCGGTGTGGGAGAAGATCTGCGACGTGATCGGCGAGACCGGCTGGAAGACCCATCCGGACT
ACGCGACGCCGCCGGCGCGGCTGAAGCACCTCAACGACATCTTCGCCCGCATCGAACAATGGACCATGACCAAGACCAAG
TTCGAGGCGATGGACATCCTCAACAGGGACGACATTCCCTGCGGGCCGATCCTGTCGATGAAGGAACTCGCCGAGGACGC
CTCGCTGCGCGCCACCGGCACGATCGTCGAGGTCGATCATCCGACCCGCGGCAAATATCTGTCGGTCGGCAACCCGATCA
AACTGTCGGACTCGCCGACCCATGTCGAGCGCTCGCCGCTTCTCGGCGAGCACACCGACGAAATTCTGCGCGACGTCCTC
GGCTTCAACGATCATCAGGTCGCTGAAATCCACGATTCCGGCGCACTCGCTCCGCCGCGCAAGCAGGCCGCAGAGTAA

Upstream 100 bases:

>100_bases
ATTGCTTCGCTTCGCTCGCGATGACGAGGGCAAACCTGTTTCTATTGACCATTCGATCAGCCGCTGACGAATCGGCTGTC
AGACACCACGGAGTAACCCA

Downstream 100 bases:

>100_bases
TCGAGGCGGCGGCGACAGCACCGCCTGTCGCCGCCGCCTCGCAAAATCTTATACTACGCCTCGCAAAATTTTACGCGGCG
CGCGATCGAACTCCAGTAAT

Product: formyl-coenzyme A transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTKALDGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGTGDITRGQLQDIPKVDSLYFTMLNHNKRSITLDTKNPKGK
EVLTALIRSCDVLVENFGPGVLDRMGFTWDKIQEINPRMIVASIKGFGPGPYEDCKVYENVAQCTGGAASTTGFRDGPPL
VTGAQIGDSGTGLHLALGIVTALYQRHHTGRGQRVTAAMQDGVLNLSRVKLRDQQRLAHGPLKEYSQFGEGIPFGDAVPR
AGNDSGGGQPGRILKCKGWETDPNAYIYFIAQAPVWEKICDVIGETGWKTHPDYATPPARLKHLNDIFARIEQWTMTKTK
FEAMDILNRDDIPCGPILSMKELAEDASLRATGTIVEVDHPTRGKYLSVGNPIKLSDSPTHVERSPLLGEHTDEILRDVL
GFNDHQVAEIHDSGALAPPRKQAAE

Sequences:

>Translated_425_residues
MTKALDGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGTGDITRGQLQDIPKVDSLYFTMLNHNKRSITLDTKNPKGK
EVLTALIRSCDVLVENFGPGVLDRMGFTWDKIQEINPRMIVASIKGFGPGPYEDCKVYENVAQCTGGAASTTGFRDGPPL
VTGAQIGDSGTGLHLALGIVTALYQRHHTGRGQRVTAAMQDGVLNLSRVKLRDQQRLAHGPLKEYSQFGEGIPFGDAVPR
AGNDSGGGQPGRILKCKGWETDPNAYIYFIAQAPVWEKICDVIGETGWKTHPDYATPPARLKHLNDIFARIEQWTMTKTK
FEAMDILNRDDIPCGPILSMKELAEDASLRATGTIVEVDHPTRGKYLSVGNPIKLSDSPTHVERSPLLGEHTDEILRDVL
GFNDHQVAEIHDSGALAPPRKQAAE
>Mature_424_residues
TKALDGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGTGDITRGQLQDIPKVDSLYFTMLNHNKRSITLDTKNPKGKE
VLTALIRSCDVLVENFGPGVLDRMGFTWDKIQEINPRMIVASIKGFGPGPYEDCKVYENVAQCTGGAASTTGFRDGPPLV
TGAQIGDSGTGLHLALGIVTALYQRHHTGRGQRVTAAMQDGVLNLSRVKLRDQQRLAHGPLKEYSQFGEGIPFGDAVPRA
GNDSGGGQPGRILKCKGWETDPNAYIYFIAQAPVWEKICDVIGETGWKTHPDYATPPARLKHLNDIFARIEQWTMTKTKF
EAMDILNRDDIPCGPILSMKELAEDASLRATGTIVEVDHPTRGKYLSVGNPIKLSDSPTHVERSPLLGEHTDEILRDVLG
FNDHQVAEIHDSGALAPPRKQAAE

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=419, Percent_Identity=29.3556085918854, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI300863124, Length=433, Percent_Identity=30.4849884526559, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI42794625, Length=432, Percent_Identity=27.3148148148148, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI266456254, Length=419, Percent_Identity=28.1622911694511, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI300863126, Length=152, Percent_Identity=44.078947368421, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI13376042, Length=433, Percent_Identity=26.7898383371824, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI266458397, Length=215, Percent_Identity=33.4883720930233, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI266458393, Length=215, Percent_Identity=33.4883720930233, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI266458395, Length=126, Percent_Identity=36.5079365079365, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI42822893, Length=126, Percent_Identity=36.5079365079365, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788717, Length=418, Percent_Identity=61.0047846889952, Blast_Score=490, Evalue=1e-140,
Organism=Escherichia coli, GI87082093, Length=399, Percent_Identity=32.0802005012531, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786222, Length=213, Percent_Identity=24.8826291079812, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32564160, Length=211, Percent_Identity=27.4881516587678, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115535051, Length=354, Percent_Identity=23.4463276836158, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24648431, Length=411, Percent_Identity=31.3868613138686, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24585488, Length=200, Percent_Identity=33, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 46494; Mature: 46363

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKALDGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGTGDITRGQLQDIPKVDSLYF
CCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCCHHHHEE
TMLNHNKRSITLDTKNPKGKEVLTALIRSCDVLVENFGPGVLDRMGFTWDKIQEINPRMI
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCEEE
VASIKGFGPGPYEDCKVYENVAQCTGGAASTTGFRDGPPLVTGAQIGDSGTGLHLALGIV
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHH
TALYQRHHTGRGQRVTAAMQDGVLNLSRVKLRDQQRLAHGPLKEYSQFGEGIPFGDAVPR
HHHHHHHCCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCC
AGNDSGGGQPGRILKCKGWETDPNAYIYFIAQAPVWEKICDVIGETGWKTHPDYATPPAR
CCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHH
LKHLNDIFARIEQWTMTKTKFEAMDILNRDDIPCGPILSMKELAEDASLRATGTIVEVDH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEECCEEEECCC
PTRGKYLSVGNPIKLSDSPTHVERSPLLGEHTDEILRDVLGFNDHQVAEIHDSGALAPPR
CCCCCEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCH
KQAAE
HHCCC
>Mature Secondary Structure 
TKALDGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGTGDITRGQLQDIPKVDSLYF
CCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCCHHHHEE
TMLNHNKRSITLDTKNPKGKEVLTALIRSCDVLVENFGPGVLDRMGFTWDKIQEINPRMI
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHCCCEEE
VASIKGFGPGPYEDCKVYENVAQCTGGAASTTGFRDGPPLVTGAQIGDSGTGLHLALGIV
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHH
TALYQRHHTGRGQRVTAAMQDGVLNLSRVKLRDQQRLAHGPLKEYSQFGEGIPFGDAVPR
HHHHHHHCCCCCCEEEHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCC
AGNDSGGGQPGRILKCKGWETDPNAYIYFIAQAPVWEKICDVIGETGWKTHPDYATPPAR
CCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHH
LKHLNDIFARIEQWTMTKTKFEAMDILNRDDIPCGPILSMKELAEDASLRATGTIVEVDH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEECCEEEECCC
PTRGKYLSVGNPIKLSDSPTHVERSPLLGEHTDEILRDVLGFNDHQVAEIHDSGALAPPR
CCCCCEEECCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCH
KQAAE
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA