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The map label for this gene is cobI [H]

Identifier: 86750290

GI number: 86750290

Start: 3637119

End: 3637847

Strand: Direct

Name: cobI [H]

Synonym: RPB_3179

Alternate gene names: 86750290

Gene position: 3637119-3637847 (Clockwise)

Preceding gene: 86750289

Following gene: 86750291

Centisome position: 68.22

GC content: 68.18

Gene sequence:

>729_bases
ATGACCCGCCCGACCGTCTATGGCGTCGGCGTGGGCCCCGGCGATCCGGACCTGATGAGCGTCCGTGCTGCACGGCTGGT
CGGCGCCGCCAAGGTCGTCGCTTACTTCAGGAAGGCCGGGCGCGCCGGCCACGCCCGCACCATCGTCGAAGGCCTGCTCG
CCGACGGCGTCGTCGAGGAGCCGCTCGACTATCCGGTGACCACCGAAATCCCGCTCGACGATCCCGCTTACGCTTCGACG
CTGCGCAGCTTCTACGAGGACTGCGTCGCGCGGCTGTCGGCGCATGTCGCGCAAGGCCGCGACGTGGTCGTGCTGTGCGA
AGGCGATCCGTTTCTCTACGGCTCGTTCATGCACCTCTATCATCGGCTGCTCGGCGATGTGCCGGTGGTCGTGGTGCCCG
GCATCTCCGGCATGGCGGCGTGCTGGACGGCGAGCGGGACGCCAATCACCTATGGCGACGACGTGCTGTGCGTCGTGCCC
GCGACACTGAATGCGACACGGCTCGCCGAAGCGCTGAAGACCGGCGACGCCTTCGTCATCATGAAGCTCGGCCGCAATCT
TCCCAAGGTCCGGCGTTCGCTCGAAGCCGCCGGGCTGCTCGATCGCGCCGTCTATGTCGAGCGCGGCGCGATGGCCGGCG
AGACGGTGATGCGCCTCGCCGACAAGCCGGACGATGCGGCGCCGTACTTCTCGATGATCCTCGTCCATGGACAGGGACGA
CGGCCATGA

Upstream 100 bases:

>100_bases
TGCTCGAGGCGGCCCCCGCACCCTGCGTCATCGTCCGCGGCCGTCGCGGCGGCAGCGCGATGACGGCGGCGGCGATCAAC
GCGCTGGCGAGCGAAGTCGA

Downstream 100 bases:

>100_bases
CCGGATCGGTCGTCGTCGCAGGTCTTGGCCCAGGTGCTCAGGAGCTGATCACACCCGAAGTAACCGCGGCGCTGGACGCC
GCGACCGATCTGGTCGGCTA

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTRPTVYGVGVGPGDPDLMSVRAARLVGAAKVVAYFRKAGRAGHARTIVEGLLADGVVEEPLDYPVTTEIPLDDPAYAST
LRSFYEDCVARLSAHVAQGRDVVVLCEGDPFLYGSFMHLYHRLLGDVPVVVVPGISGMAACWTASGTPITYGDDVLCVVP
ATLNATRLAEALKTGDAFVIMKLGRNLPKVRRSLEAAGLLDRAVYVERGAMAGETVMRLADKPDDAAPYFSMILVHGQGR
RP

Sequences:

>Translated_242_residues
MTRPTVYGVGVGPGDPDLMSVRAARLVGAAKVVAYFRKAGRAGHARTIVEGLLADGVVEEPLDYPVTTEIPLDDPAYAST
LRSFYEDCVARLSAHVAQGRDVVVLCEGDPFLYGSFMHLYHRLLGDVPVVVVPGISGMAACWTASGTPITYGDDVLCVVP
ATLNATRLAEALKTGDAFVIMKLGRNLPKVRRSLEAAGLLDRAVYVERGAMAGETVMRLADKPDDAAPYFSMILVHGQGR
RP
>Mature_241_residues
TRPTVYGVGVGPGDPDLMSVRAARLVGAAKVVAYFRKAGRAGHARTIVEGLLADGVVEEPLDYPVTTEIPLDDPAYASTL
RSFYEDCVARLSAHVAQGRDVVVLCEGDPFLYGSFMHLYHRLLGDVPVVVVPGISGMAACWTASGTPITYGDDVLCVVPA
TLNATRLAEALKTGDAFVIMKLGRNLPKVRRSLEAAGLLDRAVYVERGAMAGETVMRLADKPDDAAPYFSMILVHGQGRR
P

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 25858; Mature: 25727

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPTVYGVGVGPGDPDLMSVRAARLVGAAKVVAYFRKAGRAGHARTIVEGLLADGVVEE
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
PLDYPVTTEIPLDDPAYASTLRSFYEDCVARLSAHVAQGRDVVVLCEGDPFLYGSFMHLY
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
HRLLGDVPVVVVPGISGMAACWTASGTPITYGDDVLCVVPATLNATRLAEALKTGDAFVI
HHHHCCCCEEEECCCCCHHHEEECCCCCEEECCCEEEEECCCCCHHHHHHHHHCCCEEEE
MKLGRNLPKVRRSLEAAGLLDRAVYVERGAMAGETVMRLADKPDDAAPYFSMILVHGQGR
EHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCC
RP
CC
>Mature Secondary Structure 
TRPTVYGVGVGPGDPDLMSVRAARLVGAAKVVAYFRKAGRAGHARTIVEGLLADGVVEE
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
PLDYPVTTEIPLDDPAYASTLRSFYEDCVARLSAHVAQGRDVVVLCEGDPFLYGSFMHLY
CCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
HRLLGDVPVVVVPGISGMAACWTASGTPITYGDDVLCVVPATLNATRLAEALKTGDAFVI
HHHHCCCCEEEECCCCCHHHEEECCCCCEEECCCEEEEECCCCCHHHHHHHHHCCCEEEE
MKLGRNLPKVRRSLEAAGLLDRAVYVERGAMAGETVMRLADKPDDAAPYFSMILVHGQGR
EHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCC
RP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]