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The map label for this gene is cobJ [H]

Identifier: 86750291

GI number: 86750291

Start: 3637844

End: 3638605

Strand: Direct

Name: cobJ [H]

Synonym: RPB_3180

Alternate gene names: 86750291

Gene position: 3637844-3638605 (Clockwise)

Preceding gene: 86750290

Following gene: 86750293

Centisome position: 68.23

GC content: 68.5

Gene sequence:

>762_bases
ATGACCGGATCGGTCGTCGTCGCAGGTCTTGGCCCAGGTGCTCAGGAGCTGATCACACCCGAAGTAACCGCGGCGCTGGA
CGCCGCGACCGATCTGGTCGGCTACGCGCCCTATGTCGCCCGCGTCGCAGCGCGCAACGATGTCCGCCGGCACGCTTCCG
ACAATCGCGAGGAGATCGATCGCGCCTCGTTCGCGCTTCGGCTCGCGAGCGAGGGGCGGCATGTGGTGATCGTGTCCTCC
GGCGACCCCGGCGTATTCGCGATGGCGGCGGCGCTGTTCGAGGCGATCGAGGCCGGCGACCCGGCGTGGCGCGACCTCGA
CATCCGCGTGCTGCCCGGCATCAGCGCGATGTTCGCCGCCGCAGCGCGGATCGGCGCGCCGCTCGGCCATGATTTCTGCG
CGATCAACCTGTCTGACAATCTCAAGCCGTGGGAGACCGTCGAGAAGCGGCTGCGCGCGGCGGCCGAAGCCGACTTCGTG
ATCGCGCTGTACAATCCGATCTCGAAAGCGCGGCAATGGCAGCTCGACCGCGCCTTCGAACTGTTGCGCGGCATCCATCC
GGCGTCGGTGCCGGTGATCTTCGCCACCGCCGTCAGCGAGCCTCACCAGCGCATCGACGTCGTGCCGCTCGGCGATGCGC
TTCCGAGCCGTGCGGACATGCGCACCGTGGTGATGATCGGATCGTCGCAGACGCGGCTCATCCCCCGCGCCGACGGCGGC
AGCTATGTCTATACGCCACGCTCGCTGAAGGCGCCGTCATGA

Upstream 100 bases:

>100_bases
GCGCGATGGCCGGCGAGACGGTGATGCGCCTCGCCGACAAGCCGGACGATGCGGCGCCGTACTTCTCGATGATCCTCGTC
CATGGACAGGGACGACGGCC

Downstream 100 bases:

>100_bases
CCGAGCCACGCCATCACCTCGGCGACCGTGGCGACCGCGAGCCGCGCCGGCACAATCGGACGCCGGACCATCACCACCGG
CAGCCCGAGATCGCGCGCCG

Product: precorrin-3B C17-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTGSVVVAGLGPGAQELITPEVTAALDAATDLVGYAPYVARVAARNDVRRHASDNREEIDRASFALRLASEGRHVVIVSS
GDPGVFAMAAALFEAIEAGDPAWRDLDIRVLPGISAMFAAAARIGAPLGHDFCAINLSDNLKPWETVEKRLRAAAEADFV
IALYNPISKARQWQLDRAFELLRGIHPASVPVIFATAVSEPHQRIDVVPLGDALPSRADMRTVVMIGSSQTRLIPRADGG
SYVYTPRSLKAPS

Sequences:

>Translated_253_residues
MTGSVVVAGLGPGAQELITPEVTAALDAATDLVGYAPYVARVAARNDVRRHASDNREEIDRASFALRLASEGRHVVIVSS
GDPGVFAMAAALFEAIEAGDPAWRDLDIRVLPGISAMFAAAARIGAPLGHDFCAINLSDNLKPWETVEKRLRAAAEADFV
IALYNPISKARQWQLDRAFELLRGIHPASVPVIFATAVSEPHQRIDVVPLGDALPSRADMRTVVMIGSSQTRLIPRADGG
SYVYTPRSLKAPS
>Mature_252_residues
TGSVVVAGLGPGAQELITPEVTAALDAATDLVGYAPYVARVAARNDVRRHASDNREEIDRASFALRLASEGRHVVIVSSG
DPGVFAMAAALFEAIEAGDPAWRDLDIRVLPGISAMFAAAARIGAPLGHDFCAINLSDNLKPWETVEKRLRAAAEADFVI
ALYNPISKARQWQLDRAFELLRGIHPASVPVIFATAVSEPHQRIDVVPLGDALPSRADMRTVVMIGSSQTRLIPRADGGS
YVYTPRSLKAPS

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 27031; Mature: 26900

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSVVVAGLGPGAQELITPEVTAALDAATDLVGYAPYVARVAARNDVRRHASDNREEID
CCCCEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RASFALRLASEGRHVVIVSSGDPGVFAMAAALFEAIEAGDPAWRDLDIRVLPGISAMFAA
HHHHHEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHH
AARIGAPLGHDFCAINLSDNLKPWETVEKRLRAAAEADFVIALYNPISKARQWQLDRAFE
HHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHH
LLRGIHPASVPVIFATAVSEPHQRIDVVPLGDALPSRADMRTVVMIGSSQTRLIPRADGG
HHHCCCCCCCCEEEEECCCCHHHHEEEEECCCCCCCCCCCEEEEEECCCCCEEEEECCCC
SYVYTPRSLKAPS
CEEECCCCCCCCC
>Mature Secondary Structure 
TGSVVVAGLGPGAQELITPEVTAALDAATDLVGYAPYVARVAARNDVRRHASDNREEID
CCCEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RASFALRLASEGRHVVIVSSGDPGVFAMAAALFEAIEAGDPAWRDLDIRVLPGISAMFAA
HHHHHEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHH
AARIGAPLGHDFCAINLSDNLKPWETVEKRLRAAAEADFVIALYNPISKARQWQLDRAFE
HHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHH
LLRGIHPASVPVIFATAVSEPHQRIDVVPLGDALPSRADMRTVVMIGSSQTRLIPRADGG
HHHCCCCCCCCEEEEECCCCHHHHEEEEECCCCCCCCCCCEEEEEECCCCCEEEEECCCC
SYVYTPRSLKAPS
CEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]