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The map label for this gene is 86750218

Identifier: 86750218

GI number: 86750218

Start: 3538166

End: 3539119

Strand: Direct

Name: 86750218

Synonym: RPB_3105

Alternate gene names: NA

Gene position: 3538166-3539119 (Clockwise)

Preceding gene: 86750209

Following gene: 86750219

Centisome position: 66.36

GC content: 64.78

Gene sequence:

>954_bases
ATGCAGAACGAGACGCCCGTGATCGCGATCGAGGAACATTATTGGGACCCGGAGATGGTCGCTCGTTTTCCCGCCGGGGA
GAACGCTTCGCCTTTCTCGACGCTGCTGACAGAACTCGGCGACGTCCGGCTGCGCGCGATGGACGAGGCCGGGATCGACG
TGCAGGTGCTGTCGCACGGCGCACCCGCCGCGCAGAAATTGCCGCCGGATGTCGCTCCCGAGCTGACGCGGCGCGTCAAC
GATCGGCTTGCCGAAGCCTGCGCGCGTTTTCCAAACCGGTTCGCCGCCTTTGCCGCCCTCCCGACGCCGGCGCCCGAAGC
CGCGGCGCGCGAGTTGGAACGCTGCGTCCGCGACCTCGGCTTCAAGGGCGCGATGATTCACGGCCTGACCAACGGCCTAT
TCATCGACGACAAGCGATTCTGGCCGATATTCGAGGTCGCCGAAAAGCTCGACGTGCCGATTTATCTGCATCCGTCGGTC
CCCCACGCGGACGTCACGCGATACTATTACGACGACTACGCGCGCGAATTTCCGACCGTGATCCGGCCGGCCTGGGGCTT
CACCGTCGAAACCGCGACCCAGGCGATCCGGCTGATCCTGAGCCGCGCGCTGGAAAGCTATCCGCGGCTGCAGATCATCC
TCGGCCATCTCGGCGAGACCCTGCCCTTCCTGCTGTGGCGGATCAACCAGGCCCTGGCGCGGCCGGGTCAGACGCCACTC
GACTTCCGCAAGCAATTTTGCGATCACTTCCACGTCACGACCAGCGGCTTCTTCTCCACGCCGGCGCTGATCTGCACGAT
GCTGGAGCTCGGTATCGATCGCATCATGTTCGCGGTCGACTACCCCTATGTGGTGAACCGCGACGGCACCGACTGGGTCC
AGCAGTTGCAGATCTCACCGGACGACAAACGCAAGCTGGTCGGCGGCAACGCCCGCCGTCTGCTCAAGCTCTAG

Upstream 100 bases:

>100_bases
ATGTTGACTATATGGTCAACACTTGAATACCTTGTGATGATCACACGCCAATGCAATCGATATCGTCCGGCCGCAACAGC
GAAGACGCGAAGGTTTTCAG

Downstream 100 bases:

>100_bases
CCGGAAACGACGATGCAGGACGTAGCGCCTCCGGACATCCCGGCTGAACTCCGCGCGCTGATGGCGGAGATCGGCCCGAA
ATGGGCGACCAACACCAAAG

Product: amidohydrolase 2

Products: NA

Alternate protein names: Amidohydrolase/Decarboxylase; Amidohydrolase Family Protein; O-Pyrocatechuate Decarboxylase; Aminocarboxymuconate-Semialdehyde Decarboxylase; 2 3-Dihydroxybenzoic Acid Decarboxylase; 4-Oxalomesaconate Hydratase; 5-Carboxyvanillate Decarboxylase; 2-Amino-3-Carboxymuconate-6- Semialdehyde Decarboxylase; Metal-Dependent Hydrolase; Amidohydrolase 2 Family Protein; Decarboxylase; Metal Dependent Hydrolase; Amidohydrolase Family

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQNETPVIAIEEHYWDPEMVARFPAGENASPFSTLLTELGDVRLRAMDEAGIDVQVLSHGAPAAQKLPPDVAPELTRRVN
DRLAEACARFPNRFAAFAALPTPAPEAAARELERCVRDLGFKGAMIHGLTNGLFIDDKRFWPIFEVAEKLDVPIYLHPSV
PHADVTRYYYDDYAREFPTVIRPAWGFTVETATQAIRLILSRALESYPRLQIILGHLGETLPFLLWRINQALARPGQTPL
DFRKQFCDHFHVTTSGFFSTPALICTMLELGIDRIMFAVDYPYVVNRDGTDWVQQLQISPDDKRKLVGGNARRLLKL

Sequences:

>Translated_317_residues
MQNETPVIAIEEHYWDPEMVARFPAGENASPFSTLLTELGDVRLRAMDEAGIDVQVLSHGAPAAQKLPPDVAPELTRRVN
DRLAEACARFPNRFAAFAALPTPAPEAAARELERCVRDLGFKGAMIHGLTNGLFIDDKRFWPIFEVAEKLDVPIYLHPSV
PHADVTRYYYDDYAREFPTVIRPAWGFTVETATQAIRLILSRALESYPRLQIILGHLGETLPFLLWRINQALARPGQTPL
DFRKQFCDHFHVTTSGFFSTPALICTMLELGIDRIMFAVDYPYVVNRDGTDWVQQLQISPDDKRKLVGGNARRLLKL
>Mature_317_residues
MQNETPVIAIEEHYWDPEMVARFPAGENASPFSTLLTELGDVRLRAMDEAGIDVQVLSHGAPAAQKLPPDVAPELTRRVN
DRLAEACARFPNRFAAFAALPTPAPEAAARELERCVRDLGFKGAMIHGLTNGLFIDDKRFWPIFEVAEKLDVPIYLHPSV
PHADVTRYYYDDYAREFPTVIRPAWGFTVETATQAIRLILSRALESYPRLQIILGHLGETLPFLLWRINQALARPGQTPL
DFRKQFCDHFHVTTSGFFSTPALICTMLELGIDRIMFAVDYPYVVNRDGTDWVQQLQISPDDKRKLVGGNARRLLKL

Specific function: Unknown

COG id: COG2159

COG function: function code R; Predicted metal-dependent hydrolase of the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109715856, Length=295, Percent_Identity=28.135593220339, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71995651, Length=285, Percent_Identity=25.6140350877193, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35814; Mature: 35814

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNETPVIAIEEHYWDPEMVARFPAGENASPFSTLLTELGDVRLRAMDEAGIDVQVLSHG
CCCCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEHHCCCCEEEEECCC
APAAQKLPPDVAPELTRRVNDRLAEACARFPNRFAAFAALPTPAPEAAARELERCVRDLG
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
FKGAMIHGLTNGLFIDDKRFWPIFEVAEKLDVPIYLHPSVPHADVTRYYYDDYAREFPTV
CCCHHHHHCCCCEEECCCCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
IRPAWGFTVETATQAIRLILSRALESYPRLQIILGHLGETLPFLLWRINQALARPGQTPL
HCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DFRKQFCDHFHVTTSGFFSTPALICTMLELGIDRIMFAVDYPYVVNRDGTDWVQQLQISP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCC
DDKRKLVGGNARRLLKL
CHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MQNETPVIAIEEHYWDPEMVARFPAGENASPFSTLLTELGDVRLRAMDEAGIDVQVLSHG
CCCCCCEEEECCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHEEEHHCCCCEEEEECCC
APAAQKLPPDVAPELTRRVNDRLAEACARFPNRFAAFAALPTPAPEAAARELERCVRDLG
CCCHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
FKGAMIHGLTNGLFIDDKRFWPIFEVAEKLDVPIYLHPSVPHADVTRYYYDDYAREFPTV
CCCHHHHHCCCCEEECCCCCCHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
IRPAWGFTVETATQAIRLILSRALESYPRLQIILGHLGETLPFLLWRINQALARPGQTPL
HCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DFRKQFCDHFHVTTSGFFSTPALICTMLELGIDRIMFAVDYPYVVNRDGTDWVQQLQISP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCC
DDKRKLVGGNARRLLKL
CHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA