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The map label for this gene is cutL [H]

Identifier: 86750209

GI number: 86750209

Start: 3527565

End: 3529913

Strand: Direct

Name: cutL [H]

Synonym: RPB_3096

Alternate gene names: 86750209

Gene position: 3527565-3529913 (Clockwise)

Preceding gene: 86750208

Following gene: 86750218

Centisome position: 66.16

GC content: 64.2

Gene sequence:

>2349_bases
ATGGCCGAGACGGGCGGATTCATTGGAAAGTCGGTTCCGCGGCGCGAAGACAAGCGGCTTCTGACCGGCAAGGGCGAGTT
CGTCGCGGACCTCAAGCTGCCGTCGATGCTGCACGCGGCGTTCGTTCGCAGCCAGGTCGCCCATGGCCGGATCAAATCGG
TCGATCTGTCGCGCGCCCTGCGGTCACCGGGCGTCGTCTATGCGATCTCCGGGCCGGATCTCGCCAAGCTGCTGCCACCC
GTGCCCGACACGCAACTGTCGCTGCCGAAGAAATGGACGACGCGGGTCCAGCACACCTTCCTCAATCCGCAGCAACCGCT
GCTCGCTTACGACAAGGTCCGGCATGTCGGCGAGGCCGTCGCGGTCATTCTCGCAGAGAGCCGCTACCTCGCTGAAGACG
CCGCCGAGCTGGTGACCATGGAGATCGAGCCGCTGCCGGCCGTGGTAGATCCGGAAGCCGGGCTCACCCGCGACAGCGCC
GTGTTGCACGAACAATACGACACCAATCTGATCGGCGATTTCGCCATTGCCAAAGGCGACGTCGAGACAGCGCTGGCGAA
CGCGCCGCACCGCATGAAGCGCCGCTTCTATCATCATCGCTACGCCGCGATCCCGATGGAGGGCCGCGGCGTCGCCGCCA
ACTACGACGCACGCACGGATTCGATCAACATCTGGTCGGCGTGCCAGGTCATTCACTGGCTCCGCCGCGAGGCGTCGACG
GTGCTCGGCATGCCCGAAGCTCGCATTCGCTGCGTCGCGCTCGACGTCGGCGGCGGCTTCGGCGTCAAGGGCCACGTCTA
TCCCGAAGAATTGCTGATTCCTTATCTTGCGCGCGAAGTCGGCCGCCCGGTGAAATGGATCGAGGATCGGCACGAGCATT
TCATGAGCGCCTGCCATTCCCGCGACCAGACCCACGATGTAGAGTTCGGGTTCGACGACGACGGTCGTCTGCTAGCGTTC
CAGGACGAATTCCTCGTCGATTGCGGCGCCTGGAATCCGATCGGCTCCGGCATCGCCTACAACACTGCGGTGCATTTGCC
CGGCCCCTACAAATTCGAGCACTTCGCGGTGCGATCGAAGATCGTCGCCACCAACAAAGTGCCCAACGCGCCCTATCGCG
GTGCCGGCCGCCCCGAAGCGACGTTCGCGATGGAGCGGGTGATCGATCTGATCGCGGCCGAACTCGGCCTCGATCCGGCC
GACGTCCGCATGCGCAACATGATTCCGGCTTCCGAGATGCCGTATCGTCTCGGCCTTCCCTACCGGGACGGCGAGCCGAT
CGTCTACGACAGCGGCGACTATCCGGAATCGCTGCGCCAGGCATTGGCGGCACTAGGAGGTGTCGACGCCTTCCGCGATC
GGCAGCGGGCCGCACGGGCGCAAGGTCGATATTTCGGCCTCGGACTCGGATGCTACGTCGAAGGCACCGGCGTCGGACCG
TTCGAAAGCGCTACCGTCCGCGTAGACCCGACCGGCAAGATCTATCTCGCAGGCGGCGCCTGCCCGCAGGGACAAGGCAT
GGAAACGATCTTCTCGCAGATCGTCGCGGATGCCTGGCAGGTTCAACCCGATGACGTCGTCGTAGCATTGGCGGACACGA
GCGTGATCTCGATCGGCTTCGGCACCATCGCGAGCCGCAGCACCGTGAACTTGTCGGGCGCAATCCACACCGCGAGCCAA
TCGCTGCAGAAGAAGGTCTTCGCGATCGCAGCAGACATGCTCGAATGCTCGCCGGCCGACCTCGAGCTGCGCAACGGAAC
CGTCGGCCTCGTCGGCGTACCGGGCAGAGAGATTCCCCTCGCCCGCATCGCCAAAGCGGCGATGCCCGGCTGGGACAACA
AGCGACCCGCCGGTGTTTCAGCGGGGCTGGAGGAAACCGCCTACTTCGAGCCGCCGACCGTGACCTGGGCTTACGCGACG
CACGCCGCGATCGTCGAGCTCGATGTCGAACTCGGCCGCGTCGAGATCGAGAAATACGTCATCGTGCATGATTGCGGCGT
GGTGGTGAATCCGATGCTGGTCGACGGGCAGATTAACGGCGGCGCCGTGCAGGGCCTCGGCGGCGCGCTGCTGGAGGAAC
TAAGCTACGATTCGGAAGGCCAGTTGCTGGTTGGATCGTTCATGGACTATCTAGTACCGGGCGCGAGCGACGTGCCGCAT
TTCGAGCTGAAGCACATGCACTTCCCCTCGCCGCTGAATCCCTATGGCGTGAAAGGCGTCGGAGAAGGTAGCGCGATCGC
GCCGCCGGTGGTCATCGCCAATGCGGTCTCCGATGCACTCTCTCACCTCAAGGTCGAATTCAATTCGACGCCGATCAGGC
CTGAGCACATCGTCACAGCGTTCGGATAA

Upstream 100 bases:

>100_bases
GGCGGTGCTGTGCCGCTGCACCGGCTATCAGAACATCGTCACCGCGGTGCTGGAAGCGGCTGCGGCCATGCGCGGCGACG
CAAAGGCGGGAGCGTAGACC

Downstream 100 bases:

>100_bases
TCACCAAATCCAGGGCGCCAGATCTCGCTCATGTGGCGCCGCTCCCGTGGTCTTCGAGACACGCAGCGGCGGCGCCCGGC
AAGTGGCATCGCCGCACCTC

Product: carbon-monoxide dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 782; Mature: 781

Protein sequence:

>782_residues
MAETGGFIGKSVPRREDKRLLTGKGEFVADLKLPSMLHAAFVRSQVAHGRIKSVDLSRALRSPGVVYAISGPDLAKLLPP
VPDTQLSLPKKWTTRVQHTFLNPQQPLLAYDKVRHVGEAVAVILAESRYLAEDAAELVTMEIEPLPAVVDPEAGLTRDSA
VLHEQYDTNLIGDFAIAKGDVETALANAPHRMKRRFYHHRYAAIPMEGRGVAANYDARTDSINIWSACQVIHWLRREAST
VLGMPEARIRCVALDVGGGFGVKGHVYPEELLIPYLAREVGRPVKWIEDRHEHFMSACHSRDQTHDVEFGFDDDGRLLAF
QDEFLVDCGAWNPIGSGIAYNTAVHLPGPYKFEHFAVRSKIVATNKVPNAPYRGAGRPEATFAMERVIDLIAAELGLDPA
DVRMRNMIPASEMPYRLGLPYRDGEPIVYDSGDYPESLRQALAALGGVDAFRDRQRAARAQGRYFGLGLGCYVEGTGVGP
FESATVRVDPTGKIYLAGGACPQGQGMETIFSQIVADAWQVQPDDVVVALADTSVISIGFGTIASRSTVNLSGAIHTASQ
SLQKKVFAIAADMLECSPADLELRNGTVGLVGVPGREIPLARIAKAAMPGWDNKRPAGVSAGLEETAYFEPPTVTWAYAT
HAAIVELDVELGRVEIEKYVIVHDCGVVVNPMLVDGQINGGAVQGLGGALLEELSYDSEGQLLVGSFMDYLVPGASDVPH
FELKHMHFPSPLNPYGVKGVGEGSAIAPPVVIANAVSDALSHLKVEFNSTPIRPEHIVTAFG

Sequences:

>Translated_782_residues
MAETGGFIGKSVPRREDKRLLTGKGEFVADLKLPSMLHAAFVRSQVAHGRIKSVDLSRALRSPGVVYAISGPDLAKLLPP
VPDTQLSLPKKWTTRVQHTFLNPQQPLLAYDKVRHVGEAVAVILAESRYLAEDAAELVTMEIEPLPAVVDPEAGLTRDSA
VLHEQYDTNLIGDFAIAKGDVETALANAPHRMKRRFYHHRYAAIPMEGRGVAANYDARTDSINIWSACQVIHWLRREAST
VLGMPEARIRCVALDVGGGFGVKGHVYPEELLIPYLAREVGRPVKWIEDRHEHFMSACHSRDQTHDVEFGFDDDGRLLAF
QDEFLVDCGAWNPIGSGIAYNTAVHLPGPYKFEHFAVRSKIVATNKVPNAPYRGAGRPEATFAMERVIDLIAAELGLDPA
DVRMRNMIPASEMPYRLGLPYRDGEPIVYDSGDYPESLRQALAALGGVDAFRDRQRAARAQGRYFGLGLGCYVEGTGVGP
FESATVRVDPTGKIYLAGGACPQGQGMETIFSQIVADAWQVQPDDVVVALADTSVISIGFGTIASRSTVNLSGAIHTASQ
SLQKKVFAIAADMLECSPADLELRNGTVGLVGVPGREIPLARIAKAAMPGWDNKRPAGVSAGLEETAYFEPPTVTWAYAT
HAAIVELDVELGRVEIEKYVIVHDCGVVVNPMLVDGQINGGAVQGLGGALLEELSYDSEGQLLVGSFMDYLVPGASDVPH
FELKHMHFPSPLNPYGVKGVGEGSAIAPPVVIANAVSDALSHLKVEFNSTPIRPEHIVTAFG
>Mature_781_residues
AETGGFIGKSVPRREDKRLLTGKGEFVADLKLPSMLHAAFVRSQVAHGRIKSVDLSRALRSPGVVYAISGPDLAKLLPPV
PDTQLSLPKKWTTRVQHTFLNPQQPLLAYDKVRHVGEAVAVILAESRYLAEDAAELVTMEIEPLPAVVDPEAGLTRDSAV
LHEQYDTNLIGDFAIAKGDVETALANAPHRMKRRFYHHRYAAIPMEGRGVAANYDARTDSINIWSACQVIHWLRREASTV
LGMPEARIRCVALDVGGGFGVKGHVYPEELLIPYLAREVGRPVKWIEDRHEHFMSACHSRDQTHDVEFGFDDDGRLLAFQ
DEFLVDCGAWNPIGSGIAYNTAVHLPGPYKFEHFAVRSKIVATNKVPNAPYRGAGRPEATFAMERVIDLIAAELGLDPAD
VRMRNMIPASEMPYRLGLPYRDGEPIVYDSGDYPESLRQALAALGGVDAFRDRQRAARAQGRYFGLGLGCYVEGTGVGPF
ESATVRVDPTGKIYLAGGACPQGQGMETIFSQIVADAWQVQPDDVVVALADTSVISIGFGTIASRSTVNLSGAIHTASQS
LQKKVFAIAADMLECSPADLELRNGTVGLVGVPGREIPLARIAKAAMPGWDNKRPAGVSAGLEETAYFEPPTVTWAYATH
AAIVELDVELGRVEIEKYVIVHDCGVVVNPMLVDGQINGGAVQGLGGALLEELSYDSEGQLLVGSFMDYLVPGASDVPHF
ELKHMHFPSPLNPYGVKGVGEGSAIAPPVVIANAVSDALSHLKVEFNSTPIRPEHIVTAFG

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=786, Percent_Identity=24.6819338422392, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI91823271, Length=790, Percent_Identity=21.8987341772152, Blast_Score=141, Evalue=3e-33,
Organism=Escherichia coli, GI1789230, Length=778, Percent_Identity=29.8200514138817, Blast_Score=275, Evalue=7e-75,
Organism=Escherichia coli, GI1789246, Length=821, Percent_Identity=25.4567600487211, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI1786478, Length=752, Percent_Identity=25, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17540638, Length=814, Percent_Identity=22.8501228501229, Blast_Score=139, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24647193, Length=821, Percent_Identity=24.2387332521315, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17737937, Length=770, Percent_Identity=25.4545454545455, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24647199, Length=794, Percent_Identity=23.9294710327456, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647201, Length=796, Percent_Identity=23.2412060301508, Blast_Score=108, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84592; Mature: 84461

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETGGFIGKSVPRREDKRLLTGKGEFVADLKLPSMLHAAFVRSQVAHGRIKSVDLSRAL
CCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
RSPGVVYAISGPDLAKLLPPVPDTQLSLPKKWTTRVQHTFLNPQQPLLAYDKVRHVGEAV
CCCCEEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AVILAESRYLAEDAAELVTMEIEPLPAVVDPEAGLTRDSAVLHEQYDTNLIGDFAIAKGD
HHHHHCCHHHHHHHHHEEEEEECCCCCEECCCCCCCCCHHHHHHHCCCCCEECCEEECCC
VETALANAPHRMKRRFYHHRYAAIPMEGRGVAANYDARTDSINIWSACQVIHWLRREAST
HHHHHHCCCHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHH
VLGMPEARIRCVALDVGGGFGVKGHVYPEELLIPYLAREVGRPVKWIEDRHEHFMSACHS
HCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
RDQTHDVEFGFDDDGRLLAFQDEFLVDCGAWNPIGSGIAYNTAVHLPGPYKFEHFAVRSK
CCCCCCEEECCCCCCCEEEEECCEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHH
IVATNKVPNAPYRGAGRPEATFAMERVIDLIAAELGLDPADVRMRNMIPASEMPYRLGLP
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCC
YRDGEPIVYDSGDYPESLRQALAALGGVDAFRDRQRAARAQGRYFGLGLGCYVEGTGVGP
CCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCC
FESATVRVDPTGKIYLAGGACPQGQGMETIFSQIVADAWQVQPDDVVVALADTSVISIGF
CCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEC
GTIASRSTVNLSGAIHTASQSLQKKVFAIAADMLECSPADLELRNGTVGLVGVPGREIPL
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCH
ARIAKAAMPGWDNKRPAGVSAGLEETAYFEPPTVTWAYATHAAIVELDVELGRVEIEKYV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEECCEEEEEEEE
IVHDCGVVVNPMLVDGQINGGAVQGLGGALLEELSYDSEGQLLVGSFMDYLVPGASDVPH
EEEECCEEECCEEEECCCCCCHHCCHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCC
FELKHMHFPSPLNPYGVKGVGEGSAIAPPVVIANAVSDALSHLKVEFNSTPIRPEHIVTA
CEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHEEEE
FG
CC
>Mature Secondary Structure 
AETGGFIGKSVPRREDKRLLTGKGEFVADLKLPSMLHAAFVRSQVAHGRIKSVDLSRAL
CCCCCCCCCCCCCCCCCEEECCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHH
RSPGVVYAISGPDLAKLLPPVPDTQLSLPKKWTTRVQHTFLNPQQPLLAYDKVRHVGEAV
CCCCEEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AVILAESRYLAEDAAELVTMEIEPLPAVVDPEAGLTRDSAVLHEQYDTNLIGDFAIAKGD
HHHHHCCHHHHHHHHHEEEEEECCCCCEECCCCCCCCCHHHHHHHCCCCCEECCEEECCC
VETALANAPHRMKRRFYHHRYAAIPMEGRGVAANYDARTDSINIWSACQVIHWLRREAST
HHHHHHCCCHHHHHHHHHHHEEECCCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHH
VLGMPEARIRCVALDVGGGFGVKGHVYPEELLIPYLAREVGRPVKWIEDRHEHFMSACHS
HCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
RDQTHDVEFGFDDDGRLLAFQDEFLVDCGAWNPIGSGIAYNTAVHLPGPYKFEHFAVRSK
CCCCCCEEECCCCCCCEEEEECCEEEECCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHH
IVATNKVPNAPYRGAGRPEATFAMERVIDLIAAELGLDPADVRMRNMIPASEMPYRLGLP
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEECCC
YRDGEPIVYDSGDYPESLRQALAALGGVDAFRDRQRAARAQGRYFGLGLGCYVEGTGVGP
CCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCC
FESATVRVDPTGKIYLAGGACPQGQGMETIFSQIVADAWQVQPDDVVVALADTSVISIGF
CCCCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEC
GTIASRSTVNLSGAIHTASQSLQKKVFAIAADMLECSPADLELRNGTVGLVGVPGREIPL
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCCCCCH
ARIAKAAMPGWDNKRPAGVSAGLEETAYFEPPTVTWAYATHAAIVELDVELGRVEIEKYV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEEEEEEECCEEEEEEEE
IVHDCGVVVNPMLVDGQINGGAVQGLGGALLEELSYDSEGQLLVGSFMDYLVPGASDVPH
EEEECCEEECCEEEECCCCCCHHCCHHHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCC
FELKHMHFPSPLNPYGVKGVGEGSAIAPPVVIANAVSDALSHLKVEFNSTPIRPEHIVTA
CEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCHHHEEEE
FG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]