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The map label for this gene is grp [H]

Identifier: 86750202

GI number: 86750202

Start: 3520108

End: 3520590

Strand: Direct

Name: grp [H]

Synonym: RPB_3088

Alternate gene names: 86750202

Gene position: 3520108-3520590 (Clockwise)

Preceding gene: 86750184

Following gene: 86750203

Centisome position: 66.02

GC content: 57.35

Gene sequence:

>483_bases
ATGTTTGACCCAATAATGACCCAAAAAATCGATCAAATCGATCTTCGCATTCTTGCCGCCATGCAAGCTGACTCTTCGCG
TTCGCAACGCGAGCTCGCGGAGGAAGTCGGTCTGTCGCAGAATGCGTTCTGGCGGCGCCTGAAGGCGCTCGAGGCGAGCG
GCGCGATCACCGGTTACGGCGCACGCGTCTCACAGGAAGCCGTCGGTGTGCCGATGACTGTCTTCGTGATGGTTCGAACC
CGGCGGCATTCCGCCGAATGGCTCAAGCGCTTCCGGGCGCAGATCGAATCGATCTCAGAAATCGTCGCGTTCTATCGGAT
CAGCGGAGACTTCGATTACATGTTGAAGATTGCCGCCCGCGATATGGGCAACTACGACAAGGTGTATCAGACCATCATCA
ACAAGACCGAGCTGGAAACCGTGACGTCGTACTTCTCGATGGAAGCCATCATCGACGGCCGGCCGCTTCCGATCGGACGC
TGA

Upstream 100 bases:

>100_bases
CGCTGCGTCGCTTGCTGCAGCGGCCATCATGGGGGTGAGATTAATGATTGAAATGGCAAGAATGTTCACTTATTTTACCA
TCTAGCAGACTCAATTTGGT

Downstream 100 bases:

>100_bases
GGCACGCTGGTTGTGACTGGCTCCGCGCCAGTTGCGTGCGGCACGCTGGCTGCGTTCGGCGGCCGGCGCTGCGTTCGCTC
ACCTCGCAGGGCCTGAACGG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MFDPIMTQKIDQIDLRILAAMQADSSRSQRELAEEVGLSQNAFWRRLKALEASGAITGYGARVSQEAVGVPMTVFVMVRT
RRHSAEWLKRFRAQIESISEIVAFYRISGDFDYMLKIAARDMGNYDKVYQTIINKTELETVTSYFSMEAIIDGRPLPIGR

Sequences:

>Translated_160_residues
MFDPIMTQKIDQIDLRILAAMQADSSRSQRELAEEVGLSQNAFWRRLKALEASGAITGYGARVSQEAVGVPMTVFVMVRT
RRHSAEWLKRFRAQIESISEIVAFYRISGDFDYMLKIAARDMGNYDKVYQTIINKTELETVTSYFSMEAIIDGRPLPIGR
>Mature_160_residues
MFDPIMTQKIDQIDLRILAAMQADSSRSQRELAEEVGLSQNAFWRRLKALEASGAITGYGARVSQEAVGVPMTVFVMVRT
RRHSAEWLKRFRAQIESISEIVAFYRISGDFDYMLKIAARDMGNYDKVYQTIINKTELETVTSYFSMEAIIDGRPLPIGR

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=38, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1787116, Length=144, Percent_Identity=31.25, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 18235; Mature: 18235

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDPIMTQKIDQIDLRILAAMQADSSRSQRELAEEVGLSQNAFWRRLKALEASGAITGYG
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCC
ARVSQEAVGVPMTVFVMVRTRRHSAEWLKRFRAQIESISEIVAFYRISGDFDYMLKIAAR
CHHCHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DMGNYDKVYQTIINKTELETVTSYFSMEAIIDGRPLPIGR
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFDPIMTQKIDQIDLRILAAMQADSSRSQRELAEEVGLSQNAFWRRLKALEASGAITGYG
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEECCC
ARVSQEAVGVPMTVFVMVRTRRHSAEWLKRFRAQIESISEIVAFYRISGDFDYMLKIAAR
CHHCHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DMGNYDKVYQTIINKTELETVTSYFSMEAIIDGRPLPIGR
CCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]