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The map label for this gene is ksdD [H]

Identifier: 86750203

GI number: 86750203

Start: 3521475

End: 3523256

Strand: Direct

Name: ksdD [H]

Synonym: RPB_3090

Alternate gene names: 86750203

Gene position: 3521475-3523256 (Clockwise)

Preceding gene: 86750202

Following gene: 86750204

Centisome position: 66.05

GC content: 65.54

Gene sequence:

>1782_bases
ATGAGGGCAGTTGTGGATCGGACCGTCAGGACAATTGCGAGCCCTCATCAGCTCGGCGACATCGCCGAGAGCGGCTCATT
CGACGTGATCGTGGTCGGCGCCGGCGCGGCGGGAATGTCGGCGGCGTTGTTCGCGGCGATGGCCGGGCTGAAGCCGCTGC
TGGTCGAGCGTACCGACCGGATCGGCGGCACCAGCGCCTATTCGGCCGGCAGCGCCTGGATTCCCAATACGCATCACGCA
GCGTTAGTCGGCGCGGACGACAGCATCGACAAGGCCGCTCTTTATCTGCGGCATTCCGTCGGCAAGGAATCTCCGGAATC
GATGCGCCTGGCGTTCCTTGCCGACGGACCGAGAGCGGTCGCCGATCTGGAGCAGCATTCCCACGTGCAATTCCGCGCCC
GCAAATTGCACCCTGACTACAACAGCGACCTGCCGGGAGCCACGCTGAAGGGACGCGTCCTCGAGGCCGCGCCGTTCGAC
GGCCGCAAACTCGGCGATCTGTTCGATCTGGTGCGGGAACCGATCCCGGAATTCACGGTGCTTGGCGGCATGATGGTCAA
TCAGGAGGACGTGCTGAACTTCCTCGCAGCCGGCCGCTCCTGGAAGGCGTTCCGGCACTCTGCCGCCCTGCTCGCCCGGC
ACGCGATCGATCGCCGCTCGCATCGTCGCGGCACGCGGCTGATGATGGGCAATGCGCTGACAGCACGGCTGTTGCTGTCG
CTGCGGGATCGCGCAGTGCCGATGCTGTTGAACACGTCGGTCACGGCGATCGAGACGCGCGATGGCGGTCCGTTATCAGT
GACGATCGTGCAGGGCGGCTTGAGCCGCACGCTGACCTGTCGCGGCGGCCTGATCAGTGCCACCGGCGGCTTCAACCGGC
ATCCGCGCCTGCGGACTGAGCTGCTTCGAAAGCCCGTGGCGCAGTACTGCCCAGGCGCGCCGGGGCACACCGGACAGCTG
CACGATCTGCTGTCGGAACTGGGCGCGCACTACGGAGCGGACGACCGCGACAGCGCGTTCTGGGCGCCGGTGTCGGTTCG
CAAGCGAGCCGACGGCGAGACGGCAGTGTTCCCTCATTTCATCTTCGATCGCGGACGGCCGGGGACGATCACCGTCAACC
AGAGCGGACGCCGCTTCGTCAATGAGGCCCTGTCCTATCATCCCTTCACGCAGGCGATGCTCGACGCCGATCCAATCTCA
CCGTCGATCCCGGCATTTCTGATCGCCGACGAGACGGCGCTGCGGAAATATGGACTCGGCATCGTGAGGCCGGGTCGCTG
GGGTCGCGCTCTGTTCATCAGGGATGGTTACCTGACGCGTGCCGAAACTCTCGCCGAGCTTGCCACCAAATTGGGCATCT
CACCCGCCGACCTCACCGAGACAGTACGCCGCTTCAATCAGTTCGCCCGAACCGGGATCGATCAGGACTTCGGCCGTGGA
TCGACCGATTATCAGCGTATCACCGCGGGCGACATGAGCCACGGGCCGAATCCGTGCCTCGGCGCCTTGGAGACCGCGCC
GTTCTACGCCGTGCGTCTGTTCCCCGGCGATATCGGCGCTGCGACAGGCTTCGTGACCGACGAGACCGCCTGCATGCTGC
GTCAGGATGGAAGCCGCATCGAAGGGCTCTACGCCTGCGGCAACGACATGCATTCGGTGATGGGCGGAAACTATCCCGGG
CCCGGCATCACTTTGGGCCCGGCGATCGTATTCGCGCATATCGCGATTCGGGATATCGCGAGCCGCGTCACCGCAGGCAC
TGAGCCGGCCGCTGCGGCATGA

Upstream 100 bases:

>100_bases
GTCCCTATTCCATGAAAAATCACAATCAGCCTCAATTCCCGACCCGCGATTGCCTTCGACCGAAGACTTCTGTTGAATAC
CCATTCAACAGGACAACAAC

Downstream 100 bases:

>100_bases
CGTCTCGCCTGATCTCTTCTATGGCATGGTTGTTGCTTAGCAAGGTGGACATGAGTTGACTAACTAGACAGTCAAGCCAT
AGGATGGAGGCAAGGTGATC

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MRAVVDRTVRTIASPHQLGDIAESGSFDVIVVGAGAAGMSAALFAAMAGLKPLLVERTDRIGGTSAYSAGSAWIPNTHHA
ALVGADDSIDKAALYLRHSVGKESPESMRLAFLADGPRAVADLEQHSHVQFRARKLHPDYNSDLPGATLKGRVLEAAPFD
GRKLGDLFDLVREPIPEFTVLGGMMVNQEDVLNFLAAGRSWKAFRHSAALLARHAIDRRSHRRGTRLMMGNALTARLLLS
LRDRAVPMLLNTSVTAIETRDGGPLSVTIVQGGLSRTLTCRGGLISATGGFNRHPRLRTELLRKPVAQYCPGAPGHTGQL
HDLLSELGAHYGADDRDSAFWAPVSVRKRADGETAVFPHFIFDRGRPGTITVNQSGRRFVNEALSYHPFTQAMLDADPIS
PSIPAFLIADETALRKYGLGIVRPGRWGRALFIRDGYLTRAETLAELATKLGISPADLTETVRRFNQFARTGIDQDFGRG
STDYQRITAGDMSHGPNPCLGALETAPFYAVRLFPGDIGAATGFVTDETACMLRQDGSRIEGLYACGNDMHSVMGGNYPG
PGITLGPAIVFAHIAIRDIASRVTAGTEPAAAA

Sequences:

>Translated_593_residues
MRAVVDRTVRTIASPHQLGDIAESGSFDVIVVGAGAAGMSAALFAAMAGLKPLLVERTDRIGGTSAYSAGSAWIPNTHHA
ALVGADDSIDKAALYLRHSVGKESPESMRLAFLADGPRAVADLEQHSHVQFRARKLHPDYNSDLPGATLKGRVLEAAPFD
GRKLGDLFDLVREPIPEFTVLGGMMVNQEDVLNFLAAGRSWKAFRHSAALLARHAIDRRSHRRGTRLMMGNALTARLLLS
LRDRAVPMLLNTSVTAIETRDGGPLSVTIVQGGLSRTLTCRGGLISATGGFNRHPRLRTELLRKPVAQYCPGAPGHTGQL
HDLLSELGAHYGADDRDSAFWAPVSVRKRADGETAVFPHFIFDRGRPGTITVNQSGRRFVNEALSYHPFTQAMLDADPIS
PSIPAFLIADETALRKYGLGIVRPGRWGRALFIRDGYLTRAETLAELATKLGISPADLTETVRRFNQFARTGIDQDFGRG
STDYQRITAGDMSHGPNPCLGALETAPFYAVRLFPGDIGAATGFVTDETACMLRQDGSRIEGLYACGNDMHSVMGGNYPG
PGITLGPAIVFAHIAIRDIASRVTAGTEPAAAA
>Mature_593_residues
MRAVVDRTVRTIASPHQLGDIAESGSFDVIVVGAGAAGMSAALFAAMAGLKPLLVERTDRIGGTSAYSAGSAWIPNTHHA
ALVGADDSIDKAALYLRHSVGKESPESMRLAFLADGPRAVADLEQHSHVQFRARKLHPDYNSDLPGATLKGRVLEAAPFD
GRKLGDLFDLVREPIPEFTVLGGMMVNQEDVLNFLAAGRSWKAFRHSAALLARHAIDRRSHRRGTRLMMGNALTARLLLS
LRDRAVPMLLNTSVTAIETRDGGPLSVTIVQGGLSRTLTCRGGLISATGGFNRHPRLRTELLRKPVAQYCPGAPGHTGQL
HDLLSELGAHYGADDRDSAFWAPVSVRKRADGETAVFPHFIFDRGRPGTITVNQSGRRFVNEALSYHPFTQAMLDADPIS
PSIPAFLIADETALRKYGLGIVRPGRWGRALFIRDGYLTRAETLAELATKLGISPADLTETVRRFNQFARTGIDQDFGRG
STDYQRITAGDMSHGPNPCLGALETAPFYAVRLFPGDIGAATGFVTDETACMLRQDGSRIEGLYACGNDMHSVMGGNYPG
PGITLGPAIVFAHIAIRDIASRVTAGTEPAAAA

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 1,4- androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 63629; Mature: 63629

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVDRTVRTIASPHQLGDIAESGSFDVIVVGAGAAGMSAALFAAMAGLKPLLVERTDR
CCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHC
IGGTSAYSAGSAWIPNTHHAALVGADDSIDKAALYLRHSVGKESPESMRLAFLADGPRAV
CCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHH
ADLEQHSHVQFRARKLHPDYNSDLPGATLKGRVLEAAPFDGRKLGDLFDLVREPIPEFTV
HHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHH
LGGMMVNQEDVLNFLAAGRSWKAFRHSAALLARHAIDRRSHRRGTRLMMGNALTARLLLS
HCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHH
LRDRAVPMLLNTSVTAIETRDGGPLSVTIVQGGLSRTLTCRGGLISATGGFNRHPRLRTE
HHHCCCCEEECCCEEEEEECCCCCEEEEEEECCCCEEEEECCCEEECCCCCCCCCHHHHH
LLRKPVAQYCPGAPGHTGQLHDLLSELGAHYGADDRDSAFWAPVSVRKRADGETAVFPHF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHCCCCCCEECCHH
IFDRGRPGTITVNQSGRRFVNEALSYHPFTQAMLDADPISPSIPAFLIADETALRKYGLG
HHCCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCC
IVRPGRWGRALFIRDGYLTRAETLAELATKLGISPADLTETVRRFNQFARTGIDQDFGRG
EECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
STDYQRITAGDMSHGPNPCLGALETAPFYAVRLFPGDIGAATGFVTDETACMLRQDGSRI
CCCHHEEECCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCC
EGLYACGNDMHSVMGGNYPGPGITLGPAIVFAHIAIRDIASRVTAGTEPAAAA
CEEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRAVVDRTVRTIASPHQLGDIAESGSFDVIVVGAGAAGMSAALFAAMAGLKPLLVERTDR
CCHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHC
IGGTSAYSAGSAWIPNTHHAALVGADDSIDKAALYLRHSVGKESPESMRLAFLADGPRAV
CCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHH
ADLEQHSHVQFRARKLHPDYNSDLPGATLKGRVLEAAPFDGRKLGDLFDLVREPIPEFTV
HHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCHHH
LGGMMVNQEDVLNFLAAGRSWKAFRHSAALLARHAIDRRSHRRGTRLMMGNALTARLLLS
HCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHH
LRDRAVPMLLNTSVTAIETRDGGPLSVTIVQGGLSRTLTCRGGLISATGGFNRHPRLRTE
HHHCCCCEEECCCEEEEEECCCCCEEEEEEECCCCEEEEECCCEEECCCCCCCCCHHHHH
LLRKPVAQYCPGAPGHTGQLHDLLSELGAHYGADDRDSAFWAPVSVRKRADGETAVFPHF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHHCCCCCCEECCHH
IFDRGRPGTITVNQSGRRFVNEALSYHPFTQAMLDADPISPSIPAFLIADETALRKYGLG
HHCCCCCCEEEECCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEEECHHHHHHHCCC
IVRPGRWGRALFIRDGYLTRAETLAELATKLGISPADLTETVRRFNQFARTGIDQDFGRG
EECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
STDYQRITAGDMSHGPNPCLGALETAPFYAVRLFPGDIGAATGFVTDETACMLRQDGSRI
CCCHHEEECCCCCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHCCCCCC
EGLYACGNDMHSVMGGNYPGPGITLGPAIVFAHIAIRDIASRVTAGTEPAAAA
CEEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA