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The map label for this gene is clpX [H]

Identifier: 86749682

GI number: 86749682

Start: 2942364

End: 2943638

Strand: Direct

Name: clpX [H]

Synonym: RPB_2564

Alternate gene names: 86749682

Gene position: 2942364-2943638 (Clockwise)

Preceding gene: 86749681

Following gene: 86749683

Centisome position: 55.19

GC content: 62.51

Gene sequence:

>1275_bases
ATGAGTAAGGTCGGTACGAGCGACTCCAAGAACACCCTGTACTGCTCGTTCTGCGGAAAGAGCCAGCACGAGGTCCGCAA
GCTGATCGCCGGCCCCACGGTATTCATCTGTGATGAGTGCGTGGAACTGTGCATGGACATCATCCGGGAGGAGAACAAAT
CCTCGCTGGTGAAGTCGCGCGACGGCATCCCGACCCCGAAGGAAATCTGCAAGGTTCTCGACGATTACGTGATCGGCCAG
AACCATGCGAAGAAGGTGCTCTCGGTCGCGGTCCACAACCACTACAAGCGGCTGAACCACCAGACCAAGCACAACGACGT
CGAACTGGCGAAGTCGAACATCCTGCTGATCGGTCCGACCGGCTCGGGCAAGACGCTGCTGGCGCAGACGCTGGCGCGGA
TTCTCGACGTGCCGTTCACGATGGCGGATGCGACGACGCTGACCGAAGCCGGCTATGTCGGCGAGGACGTCGAGAACATC
ATCCTGAAGCTGCTGCAGGCCGCCGACTACAATGTCGAGCGGGCGCAGCGCGGCATCGTCTATATCGACGAAATCGACAA
GATCTCGCGCAAATCGGACAATCCCTCGATCACCCGCGACGTCTCGGGCGAGGGTGTCCAGCAGGCGCTCTTGAAGATCA
TGGAAGGCACTGTGGCTTCGGTCCCGCCGCAGGGCGGCCGCAAGCATCCGCAGCAGGAATTCCTGCAGGTCGACACCACC
AACATCCTGTTCATCTGCGGTGGCGCCTTCGCGGGTCTCGAAAAGATCATCTCGGCGCGCGGCCGCTCGACCTCGATCGG
CTTCGCGGCGCAAGTGCTGGCCCCGGAAGACCGCCGCACCGGCGAGATCTTCCGTCACGTCGAGCCCGAGGATCTCTTGA
AGTACGGCCTGATCCCGGAATTCGTCGGCCGTCTGCCGGTCGTGGCGACGCTCGAGGATCTCGACGAGGCCTCGCTGAAG
AAGATCCTGACCGACCCGAAGAACGCGCTGGTGAAGCAGTATCAGCGGCTGTTCGAGATGGAGAACATCGAGCTGACCTT
CGCCGACGAGGCGTTGGGTGCGGTGGCGCGCAAGGCGATCGAGCGCAAGACCGGCGCCCGAGGCCTGCGGTCGATCCTCG
AAAGCATCCTGCTCGAGACGATGTTCGATCTGCCGGGTCTCGAAGGCGTCGAGGAAGTGGTGATCTCGCGCGAAGTCGTC
GATGGCACGGCGCGTCCGCTCTACATCTATGCCGACCGCTCCGATCGCGCGGCAGAGAGCAGCGCCAGCGCATAA

Upstream 100 bases:

>100_bases
TCTTTTCTGGTACGGGATTTGCTCCATTTCTACCAACTCTGCCGGGTTCTGCCGGAAGACGAGGGCACCAGAGAAGACCG
AACTGCGGACGGAGAACGAA

Downstream 100 bases:

>100_bases
TGGCCACCGACCGCACGCGGAAGTCCGCGCGAAGGGTCCTTCAAACGCGGGCTGCCGAGACCTCTCGGCAGCCCGATTTC
GTCTCCGCTGCGGGGCAGTC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSKVGTSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQ
NHAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDEASLK
KILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVV
DGTARPLYIYADRSDRAAESSASA

Sequences:

>Translated_424_residues
MSKVGTSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQ
NHAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDEASLK
KILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVV
DGTARPLYIYADRSDRAAESSASA
>Mature_423_residues
SKVGTSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQN
HAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDEASLKK
ILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVD
GTARPLYIYADRSDRAAESSASA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=346, Percent_Identity=52.3121387283237, Blast_Score=335, Evalue=6e-92,
Organism=Escherichia coli, GI1786642, Length=406, Percent_Identity=72.4137931034483, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=45.2830188679245, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71982908, Length=313, Percent_Identity=47.6038338658147, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71982905, Length=313, Percent_Identity=47.6038338658147, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=37.8516624040921, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.4858299595142, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=447, Percent_Identity=37.5838926174497, Blast_Score=264, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24648291, Length=336, Percent_Identity=47.3214285714286, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24648289, Length=339, Percent_Identity=46.9026548672566, Blast_Score=303, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46594; Mature: 46463

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVGTSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DGIPTPKEICKVLDDYVIGQNHAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCHHHHHHCCCHHHHHHHCCCHH
FVGRLPVVATLEDLDEASLKKILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAI
HHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
ERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVDGTARPLYIYADRSDRAAES
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHCCC
SASA
CCCC
>Mature Secondary Structure 
SKVGTSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSR
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DGIPTPKEICKVLDDYVIGQNHAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPT
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCHHHHHHCCCHHHHHHHCCCHH
FVGRLPVVATLEDLDEASLKKILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAI
HHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
ERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVDGTARPLYIYADRSDRAAES
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHCCC
SASA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA