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The map label for this gene is ompR [H]

Identifier: 86749494

GI number: 86749494

Start: 2728420

End: 2729157

Strand: Reverse

Name: ompR [H]

Synonym: RPB_2374

Alternate gene names: 86749494

Gene position: 2729157-2728420 (Counterclockwise)

Preceding gene: 86749497

Following gene: 86749493

Centisome position: 51.19

GC content: 68.16

Gene sequence:

>738_bases
ATGGCCGATCAACCACAGTTGCCGCACATCCTGGTCGTCGACGATCACCGCGAGATCCGCGAGGCGGTGACAAAATACCT
CGAGCGCAACGGCATGCGCGCCAGCGCCGCCAGCAACACGGTCGAGATGGACGCTCAGCTCAAGGCCGGACGGTTCGACC
TGATCATCCTCGACGTGATGATGCCCGGCGAGGATGGGCTGTCGGCAGCGCGGCGGCTGAGCACAGGCGGCGGCCCGCCG
GTGCTGATGCTGAGCGCGCTGTCGGACGAGACCGACCGCGTGGTCGGGCTGGAGATCGGCGCCGACGATTATCTCGCCAA
GCCGTTCAGCCCGCGCGAATTGCTGGCGCGGATCAAGGCGATCCTGCGCCGGAGCGAACGGCGCGAGCCGCTCGCCGGGA
CGCTGGGCGGCCGCAAGCTCGGCTTCGCCGGCTGGTTGCTCGACACCGATACCCGCGACCTCGTCCGCGACGCCGACCGC
GCGGAGAAAATCGCCCTGACGACGGCGGAGTTCAAGCTGCTGGTGGCGTTTCTGGAACGGCCGCGGTTCGTGTTGACGCG
CGAGCAGTTGCTCGACATCACCAGCGGCCGCAGCGCCGACGTGTTCGACCGCACCATCGACAACCAGGTGAGCCGGCTGC
GTCGCAAGATCGAGGACGATCCGGCGCATCCGAAGATCATCACCACGGTTCGCTCCGGCGGCTACAGCCTCGCCGCCGAC
GTCCGGGAGCTGCCATGA

Upstream 100 bases:

>100_bases
CCGCTTGGAGATTTGTATCGGTCTGTCGCAAGACGCCGGCCTGCGATGATTTGCGACAGAAGTCTTTTCCGGCGCGGGGC
AAGTCGGGCTAGATCAAGAC

Downstream 100 bases:

>100_bases
GCCGCCGCAGGCCGCGCAGCCTTCTCACCCAGGTGGCGCTGCTCAGCTTCGCAGCGCTCCTCGTCGCCCAGTTCGTCAGT
TTCTGGCTGTTCACAGCCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MADQPQLPHILVVDDHREIREAVTKYLERNGMRASAASNTVEMDAQLKAGRFDLIILDVMMPGEDGLSAARRLSTGGGPP
VLMLSALSDETDRVVGLEIGADDYLAKPFSPRELLARIKAILRRSERREPLAGTLGGRKLGFAGWLLDTDTRDLVRDADR
AEKIALTTAEFKLLVAFLERPRFVLTREQLLDITSGRSADVFDRTIDNQVSRLRRKIEDDPAHPKIITTVRSGGYSLAAD
VRELP

Sequences:

>Translated_245_residues
MADQPQLPHILVVDDHREIREAVTKYLERNGMRASAASNTVEMDAQLKAGRFDLIILDVMMPGEDGLSAARRLSTGGGPP
VLMLSALSDETDRVVGLEIGADDYLAKPFSPRELLARIKAILRRSERREPLAGTLGGRKLGFAGWLLDTDTRDLVRDADR
AEKIALTTAEFKLLVAFLERPRFVLTREQLLDITSGRSADVFDRTIDNQVSRLRRKIEDDPAHPKIITTVRSGGYSLAAD
VRELP
>Mature_244_residues
ADQPQLPHILVVDDHREIREAVTKYLERNGMRASAASNTVEMDAQLKAGRFDLIILDVMMPGEDGLSAARRLSTGGGPPV
LMLSALSDETDRVVGLEIGADDYLAKPFSPRELLARIKAILRRSERREPLAGTLGGRKLGFAGWLLDTDTRDLVRDADRA
EKIALTTAEFKLLVAFLERPRFVLTREQLLDITSGRSADVFDRTIDNQVSRLRRKIEDDPAHPKIITTVRSGGYSLAADV
RELP

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=44.3965517241379, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1790863, Length=243, Percent_Identity=33.7448559670782, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=40.343347639485, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=35.042735042735, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=38.4279475982533, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=38.3620689655172, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.9344978165939, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=34.051724137931, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=36.0869565217391, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=32.2175732217573, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=30.7017543859649, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=29.7071129707113, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=29.1304347826087, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27185; Mature: 27053

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQPQLPHILVVDDHREIREAVTKYLERNGMRASAASNTVEMDAQLKAGRFDLIILDVM
CCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCEECCCCEEEEEEEEE
MPGEDGLSAARRLSTGGGPPVLMLSALSDETDRVVGLEIGADDYLAKPFSPRELLARIKA
ECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHH
ILRRSERREPLAGTLGGRKLGFAGWLLDTDTRDLVRDADRAEKIALTTAEFKLLVAFLER
HHHHHHCCCCCHHCCCCCEECEEEEEECCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHHC
PRFVLTREQLLDITSGRSADVFDRTIDNQVSRLRRKIEDDPAHPKIITTVRSGGYSLAAD
CCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEHH
VRELP
HHHCC
>Mature Secondary Structure 
ADQPQLPHILVVDDHREIREAVTKYLERNGMRASAASNTVEMDAQLKAGRFDLIILDVM
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCEECCCCEEEEEEEEE
MPGEDGLSAARRLSTGGGPPVLMLSALSDETDRVVGLEIGADDYLAKPFSPRELLARIKA
ECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHCCCCCHHHHHHHHHH
ILRRSERREPLAGTLGGRKLGFAGWLLDTDTRDLVRDADRAEKIALTTAEFKLLVAFLER
HHHHHHCCCCCHHCCCCCEECEEEEEECCCHHHHHHHHHHHHEEEEHHHHHHHHHHHHHC
PRFVLTREQLLDITSGRSADVFDRTIDNQVSRLRRKIEDDPAHPKIITTVRSGGYSLAAD
CCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEHH
VRELP
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]