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The map label for this gene is mcp4 [H]

Identifier: 86749478

GI number: 86749478

Start: 2711186

End: 2713207

Strand: Reverse

Name: mcp4 [H]

Synonym: RPB_2358

Alternate gene names: 86749478

Gene position: 2713207-2711186 (Counterclockwise)

Preceding gene: 86749483

Following gene: 86749477

Centisome position: 50.89

GC content: 65.97

Gene sequence:

>2022_bases
ATGATGAAATTCGATCGAATTGGTAACAAGCTCGGCCTGGCAGGCTTGCTGGGTGTGGTGTTGGCCGGCGGCATGCTGGT
CAACCAGATGATGGCCGAGCAAAAGATCGCGGCGGCCAACACGCTCGCCGAGCGTCAGCAATACATCAACGAACACACGC
TGGAAGCCAACATCGCCTTGCGGCGGATACAGCTCGCGGTGCGCGATATCAGGCTCGCCAAGACTCCCGCCGAGCTCGAG
AAGCCGGTCGCAGCCCTGGCGGAGATGGCGGCGCGCACCCAGAAAGAACTCGAAGCAGCCGCTGCGCGCGCCGCGCGGCC
GGAGACCAAGCAACGGTTCGAGAAAATCAAGGCGCTCGCCAAGGACTACGAAACGCAGGCATCGGCGCAGGTCAAAACCA
TCCAGCAAGCGTTCGCGATGGCCGCCAAGCGGGGCCAAGTGACGAGCGACTGGGGCAAGGCCTTCGAAGCCCTGAAGGCT
TCTCCGGCGATCGCCGCGAGCCGCCTCGAGGTCGAGCGGGCGATGTACGAAGCGGATTCGCACTTCAACGCGATCCGCGC
GGCGAACTGGCGGTTTACCGCGAGCGGGGAAGACAGCCAGAGGAAGGTCATCGAACTCCGCGCCACCGCCCTGAACGATG
CGCTGGCCCGGCTGCGCAATATCTCCAACGACAAGGCGCTGACCACAGCCGCCGACCAGCTCTCGGCCGACGCCAAGACC
TTTGTCGGGATGGCCAATGACGCAGTGAAGCTCGACAGCACCAGGAACGGGCAGTCGGCCTCGATGCTGACGATCGCCGA
CCAGATGGGCCCATTGATGCGGGAAGCCGTCGACGCCTCCAGCAACAGCTTCCGCACCGCCAAGGAGACCGCCGAAGCCG
AGCTCGAGTCGGCCAACCGGATCAGCTTCATGGCTGCCGTCGCCGTGATGCTGGCGCTGATCGGCTCGGTGATCTTCACC
TTCATCGGCGTCGCCCGCCCGCTCACCCTGCTGAACAACGCGCTCGGCCGGATCGCGGCCGGCGAACTCAATGCCGATAT
TCCCGGCGCAACCCGCGGCGACGAAGTCGGCGATATCGCCAAGACCGTGGTGGTGATCAGCAAGAACGCCGAACAGAAGG
CCCGCGACGAAGCCGAAGCCCAGGCCAAGCAGGAGCAGATCGCCGCGCAGCGTCGCAAGGCCGATATGATCCAGCTCGCC
GACAGCTTCGAAGCCGCCGTCGGCGAGATCGTCGACACGGTGTCGTCGGCCTCGACCGAGCTCGAAGCCTCGGCCTCGAC
GCTGACGTCGACCGCCGAACGCTCGCAGGAACTCACCACCATGGTGGCGGCGGCCTCTGAGGAAGCCTCCACCAACGTGC
AGTCGGTGGCCTCCGCGACCGAGGAGCTGTCGTCCTCCGTCAACGAGATCAGCCGTCAGGTGCAGGAATCGGCGCGGATG
GCCAATGAGGCGGTCAACCAGGCACGCACCACCAACGATCGCGTCGGCGAACTGTCCAAGGCCGCCGCCCGGATCGGCGA
CGTCGTCGAACTGATCAACACCATCGCCGGCCAGACCAACCTGCTCGCGCTCAACGCCACCATCGAGGCGGCGCGCGCCG
GTGAAGCCGGTCGCGGCTTCGCGGTCGTCGCCTCCGAAGTGAAAGCGCTGGCCGAGCAGACCGCCAAGGCGACCGGCGAC
ATCAGTCAGCAGATCTCCAGCATCCAGACCGCCACCCAGGACTCGGTGGGCGCGATCCGGGATATCAGCGGCACCATCGA
GAAACTGTCCGAGATCGCCTCCACCATCGCCTCGGCGGTCGAAGAACAGGGCGCCGCGACGCAGGAGATCTCCCGCAACG
TGCAGCAGGCTTCGCAAGGCACGCAGCAGGTCTCCGCCAACATCACCGACGTGCAGCGCGGCGCCACCGAAACCGGCTCG
GCCTCGGCGCAAGTGCTCTCGGCGGCCCAAACGCTCTCCAGCGACAGCAACCGCCTCCGGAGCGAAGTGGGCAAATTCCT
CAGCACCGTCCGCGCCGCGTAA

Upstream 100 bases:

>100_bases
GCGCAAGTTTCATCAATCTCTAAGGCGATGATCAACATAGTTACCCCGCTATTATTCGGACTCCCTCCGAACGTCGACGT
CAACCCTGGGATTCTGCGCG

Downstream 100 bases:

>100_bases
CGACGACAGAGCCCGGCTCCGCATGGAGCCGGGCTTTTCGACCTGCACATCGAGATTGCGACCATCGGGCCGTGGAGTCG
TGCCGCCATCCGGCACTGCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MMKFDRIGNKLGLAGLLGVVLAGGMLVNQMMAEQKIAAANTLAERQQYINEHTLEANIALRRIQLAVRDIRLAKTPAELE
KPVAALAEMAARTQKELEAAAARAARPETKQRFEKIKALAKDYETQASAQVKTIQQAFAMAAKRGQVTSDWGKAFEALKA
SPAIAASRLEVERAMYEADSHFNAIRAANWRFTASGEDSQRKVIELRATALNDALARLRNISNDKALTTAADQLSADAKT
FVGMANDAVKLDSTRNGQSASMLTIADQMGPLMREAVDASSNSFRTAKETAEAELESANRISFMAAVAVMLALIGSVIFT
FIGVARPLTLLNNALGRIAAGELNADIPGATRGDEVGDIAKTVVVISKNAEQKARDEAEAQAKQEQIAAQRRKADMIQLA
DSFEAAVGEIVDTVSSASTELEASASTLTSTAERSQELTTMVAAASEEASTNVQSVASATEELSSSVNEISRQVQESARM
ANEAVNQARTTNDRVGELSKAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGD
ISQQISSIQTATQDSVGAIRDISGTIEKLSEIASTIASAVEEQGAATQEISRNVQQASQGTQQVSANITDVQRGATETGS
ASAQVLSAAQTLSSDSNRLRSEVGKFLSTVRAA

Sequences:

>Translated_673_residues
MMKFDRIGNKLGLAGLLGVVLAGGMLVNQMMAEQKIAAANTLAERQQYINEHTLEANIALRRIQLAVRDIRLAKTPAELE
KPVAALAEMAARTQKELEAAAARAARPETKQRFEKIKALAKDYETQASAQVKTIQQAFAMAAKRGQVTSDWGKAFEALKA
SPAIAASRLEVERAMYEADSHFNAIRAANWRFTASGEDSQRKVIELRATALNDALARLRNISNDKALTTAADQLSADAKT
FVGMANDAVKLDSTRNGQSASMLTIADQMGPLMREAVDASSNSFRTAKETAEAELESANRISFMAAVAVMLALIGSVIFT
FIGVARPLTLLNNALGRIAAGELNADIPGATRGDEVGDIAKTVVVISKNAEQKARDEAEAQAKQEQIAAQRRKADMIQLA
DSFEAAVGEIVDTVSSASTELEASASTLTSTAERSQELTTMVAAASEEASTNVQSVASATEELSSSVNEISRQVQESARM
ANEAVNQARTTNDRVGELSKAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGD
ISQQISSIQTATQDSVGAIRDISGTIEKLSEIASTIASAVEEQGAATQEISRNVQQASQGTQQVSANITDVQRGATETGS
ASAQVLSAAQTLSSDSNRLRSEVGKFLSTVRAA
>Mature_673_residues
MMKFDRIGNKLGLAGLLGVVLAGGMLVNQMMAEQKIAAANTLAERQQYINEHTLEANIALRRIQLAVRDIRLAKTPAELE
KPVAALAEMAARTQKELEAAAARAARPETKQRFEKIKALAKDYETQASAQVKTIQQAFAMAAKRGQVTSDWGKAFEALKA
SPAIAASRLEVERAMYEADSHFNAIRAANWRFTASGEDSQRKVIELRATALNDALARLRNISNDKALTTAADQLSADAKT
FVGMANDAVKLDSTRNGQSASMLTIADQMGPLMREAVDASSNSFRTAKETAEAELESANRISFMAAVAVMLALIGSVIFT
FIGVARPLTLLNNALGRIAAGELNADIPGATRGDEVGDIAKTVVVISKNAEQKARDEAEAQAKQEQIAAQRRKADMIQLA
DSFEAAVGEIVDTVSSASTELEASASTLTSTAERSQELTTMVAAASEEASTNVQSVASATEELSSSVNEISRQVQESARM
ANEAVNQARTTNDRVGELSKAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGFAVVASEVKALAEQTAKATGD
ISQQISSIQTATQDSVGAIRDISGTIEKLSEIASTIASAVEEQGAATQEISRNVQQASQGTQQVSANITDVQRGATETGS
ASAQVLSAAQTLSSDSNRLRSEVGKFLSTVRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=385, Percent_Identity=28.051948051948, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI2367378, Length=250, Percent_Identity=32.8, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1787690, Length=228, Percent_Identity=33.7719298245614, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788195, Length=241, Percent_Identity=31.5352697095436, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1789453, Length=228, Percent_Identity=30.2631578947368, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 71031; Mature: 71031

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKFDRIGNKLGLAGLLGVVLAGGMLVNQMMAEQKIAAANTLAERQQYINEHTLEANIAL
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRIQLAVRDIRLAKTPAELEKPVAALAEMAARTQKELEAAAARAARPETKQRFEKIKALA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KDYETQASAQVKTIQQAFAMAAKRGQVTSDWGKAFEALKASPAIAASRLEVERAMYEADS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HFNAIRAANWRFTASGEDSQRKVIELRATALNDALARLRNISNDKALTTAADQLSADAKT
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FVGMANDAVKLDSTRNGQSASMLTIADQMGPLMREAVDASSNSFRTAKETAEAELESANR
HHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ISFMAAVAVMLALIGSVIFTFIGVARPLTLLNNALGRIAAGELNADIPGATRGDEVGDIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
KTVVVISKNAEQKARDEAEAQAKQEQIAAQRRKADMIQLADSFEAAVGEIVDTVSSASTE
HHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEASASTLTSTAERSQELTTMVAAASEEASTNVQSVASATEELSSSVNEISRQVQESARM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANEAVNQARTTNDRVGELSKAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCH
AVVASEVKALAEQTAKATGDISQQISSIQTATQDSVGAIRDISGTIEKLSEIASTIASAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEQGAATQEISRNVQQASQGTQQVSANITDVQRGATETGSASAQVLSAAQTLSSDSNRLR
HHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SEVGKFLSTVRAA
HHHHHHHHHHHCC
>Mature Secondary Structure
MMKFDRIGNKLGLAGLLGVVLAGGMLVNQMMAEQKIAAANTLAERQQYINEHTLEANIAL
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRIQLAVRDIRLAKTPAELEKPVAALAEMAARTQKELEAAAARAARPETKQRFEKIKALA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
KDYETQASAQVKTIQQAFAMAAKRGQVTSDWGKAFEALKASPAIAASRLEVERAMYEADS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
HFNAIRAANWRFTASGEDSQRKVIELRATALNDALARLRNISNDKALTTAADQLSADAKT
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FVGMANDAVKLDSTRNGQSASMLTIADQMGPLMREAVDASSNSFRTAKETAEAELESANR
HHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ISFMAAVAVMLALIGSVIFTFIGVARPLTLLNNALGRIAAGELNADIPGATRGDEVGDIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
KTVVVISKNAEQKARDEAEAQAKQEQIAAQRRKADMIQLADSFEAAVGEIVDTVSSASTE
HHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEASASTLTSTAERSQELTTMVAAASEEASTNVQSVASATEELSSSVNEISRQVQESARM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANEAVNQARTTNDRVGELSKAAARIGDVVELINTIAGQTNLLALNATIEAARAGEAGRGF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCH
AVVASEVKALAEQTAKATGDISQQISSIQTATQDSVGAIRDISGTIEKLSEIASTIASAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEQGAATQEISRNVQQASQGTQQVSANITDVQRGATETGSASAQVLSAAQTLSSDSNRLR
HHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHH
SEVGKFLSTVRAA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]