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The map label for this gene is nlpC [C]

Identifier: 86748899

GI number: 86748899

Start: 2037082

End: 2037966

Strand: Reverse

Name: nlpC [C]

Synonym: RPB_1776

Alternate gene names: 86748899

Gene position: 2037966-2037082 (Counterclockwise)

Preceding gene: 86748900

Following gene: 86748891

Centisome position: 38.22

GC content: 69.38

Gene sequence:

>885_bases
ATGGCTGATCTGAAGCTCGATCCGCGGCTGACGCCGGCGCGGCCGGATCTCGCGGCGAAACATCTCGAAGGCCGGGTGAG
CGCGGACCGTTTCGTCGACGGCGAAATCTTCGAGATCAGCTACGGCGTGGCGCCGGTGCGGTGCGAGCCGTTTTCCGGGG
CGATGCTGCAGACCGAAGCGCTTAAGGGCGAGCGCGTCACCGTCTACGACCGCGACGAGGAAGGCTGGGCCTGGGGCCAG
CTCATGACCGACGGCTATGTCGGCTGGCTGCCTGACCTCGCGCTGTACCGGCCCGGCGCGGAGCCGACCCACAGAGTGAC
GGCGCTGCGCAGCTTTGCCTTTCCAGGCCCGTCGATCAAACTGCCGCCGGCGGAGACGCTGCCGCTCGGCGCGCGGCTGG
CGGTGGTGCGCGACGACGCGAGCTTCGCGGTGACGCAAGAGGGCTGGTACGTGCCGCGCCGACATGTCGAGCCGATCGAT
CGGTTCGAGAGCGATTTCGTCGCGGTCGCCGAGCGCTTCGTCGGCACGCCGTATCTGTGGGGCGGCCGCTCGAGCCTCGG
CATCGACTGCTCCGGCCTGGTGCAGACCGCCCTCGCTGCCTGCAGCATCCAAGCGCCGCGCGACAGCGACATGCAGGAGG
CGGCGCTGGGCGAACCGCTGGTGCTGTCGGAGCAGACCAGGCTGCAGCGCGGCGATCTGCTGTTCTGGAAGGGCCACGTC
GCGATCGTGCGCGACCAGGGCAGCATTGTCCACGCCAATGCGTATGCGATGGCGACCGCAATCGAGCCTGTGCACGCGGC
GATCGCGCGGATCGCAGCAAGCGGCAGCGAGCTCACCGCGATCAGGCGGCTCGGTCGAACAGCTCCCGCAGCCGGGATCG
GTTGA

Upstream 100 bases:

>100_bases
GTCGACATCTACGGCTGGACGCCGAAGGCCAAGCCGGCGCGGCCCGAAGGCGGCGAGTGCCAGGCCGCGCGCGCGATCTT
CGCATTGCTGAGCGAACGCT

Downstream 100 bases:

>100_bases
GCGCCAGCCATTGCAGCGCGCCGACCAGCAGCGCATTGGCGACCTGCCCGCGCTCGAGCGCAGCCAGCGCCTCGTCGATC
GACACCACGAAGGGCTGGGT

Product: NLP/P60

Products: NA

Alternate protein names: Dipeptidyl-peptidase VI; DPP VI; Endopeptidase II; Gamma-D-glutamyl-L-diamino acid endopeptidase II; Gamma-D-glutamyl-MESO-diaminopimelate peptidase II [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MADLKLDPRLTPARPDLAAKHLEGRVSADRFVDGEIFEISYGVAPVRCEPFSGAMLQTEALKGERVTVYDRDEEGWAWGQ
LMTDGYVGWLPDLALYRPGAEPTHRVTALRSFAFPGPSIKLPPAETLPLGARLAVVRDDASFAVTQEGWYVPRRHVEPID
RFESDFVAVAERFVGTPYLWGGRSSLGIDCSGLVQTALAACSIQAPRDSDMQEAALGEPLVLSEQTRLQRGDLLFWKGHV
AIVRDQGSIVHANAYAMATAIEPVHAAIARIAASGSELTAIRRLGRTAPAAGIG

Sequences:

>Translated_294_residues
MADLKLDPRLTPARPDLAAKHLEGRVSADRFVDGEIFEISYGVAPVRCEPFSGAMLQTEALKGERVTVYDRDEEGWAWGQ
LMTDGYVGWLPDLALYRPGAEPTHRVTALRSFAFPGPSIKLPPAETLPLGARLAVVRDDASFAVTQEGWYVPRRHVEPID
RFESDFVAVAERFVGTPYLWGGRSSLGIDCSGLVQTALAACSIQAPRDSDMQEAALGEPLVLSEQTRLQRGDLLFWKGHV
AIVRDQGSIVHANAYAMATAIEPVHAAIARIAASGSELTAIRRLGRTAPAAGIG
>Mature_293_residues
ADLKLDPRLTPARPDLAAKHLEGRVSADRFVDGEIFEISYGVAPVRCEPFSGAMLQTEALKGERVTVYDRDEEGWAWGQL
MTDGYVGWLPDLALYRPGAEPTHRVTALRSFAFPGPSIKLPPAETLPLGARLAVVRDDASFAVTQEGWYVPRRHVEPIDR
FESDFVAVAERFVGTPYLWGGRSSLGIDCSGLVQTALAACSIQAPRDSDMQEAALGEPLVLSEQTRLQRGDLLFWKGHVA
IVRDQGSIVHANAYAMATAIEPVHAAIARIAASGSELTAIRRLGRTAPAAGIG

Specific function: Involved in cell sporulation. Hydrolyzes gamma-D-Glu-L- (meso)A2pm linkages only in those peptide units that have a free N-terminal L-alanine [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C40 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064 [H]

Pfam domain/function: PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 31845; Mature: 31713

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLKLDPRLTPARPDLAAKHLEGRVSADRFVDGEIFEISYGVAPVRCEPFSGAMLQTEA
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCEEEHHH
LKGERVTVYDRDEEGWAWGQLMTDGYVGWLPDLALYRPGAEPTHRVTALRSFAFPGPSIK
CCCCEEEEEECCCCCCEEEEECCCCCCHHCCCHHHCCCCCCHHHHHHHHHHHCCCCCCEE
LPPAETLPLGARLAVVRDDASFAVTQEGWYVPRRHVEPIDRFESDFVAVAERFVGTPYLW
CCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
GGRSSLGIDCSGLVQTALAACSIQAPRDSDMQEAALGEPLVLSEQTRLQRGDLLFWKGHV
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEECCHHHHCCCCEEEEECCE
AIVRDQGSIVHANAYAMATAIEPVHAAIARIAASGSELTAIRRLGRTAPAAGIG
EEEECCCCEEEECCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADLKLDPRLTPARPDLAAKHLEGRVSADRFVDGEIFEISYGVAPVRCEPFSGAMLQTEA
CCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCEEEHHH
LKGERVTVYDRDEEGWAWGQLMTDGYVGWLPDLALYRPGAEPTHRVTALRSFAFPGPSIK
CCCCEEEEEECCCCCCEEEEECCCCCCHHCCCHHHCCCCCCHHHHHHHHHHHCCCCCCEE
LPPAETLPLGARLAVVRDDASFAVTQEGWYVPRRHVEPIDRFESDFVAVAERFVGTPYLW
CCCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
GGRSSLGIDCSGLVQTALAACSIQAPRDSDMQEAALGEPLVLSEQTRLQRGDLLFWKGHV
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEECCHHHHCCCCEEEEECCE
AIVRDQGSIVHANAYAMATAIEPVHAAIARIAASGSELTAIRRLGRTAPAAGIG
EEEECCCCEEEECCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1587462; 1551459 [H]