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The map label for this gene is kdsB [H]

Identifier: 86748891

GI number: 86748891

Start: 2026750

End: 2027529

Strand: Reverse

Name: kdsB [H]

Synonym: RPB_1768

Alternate gene names: 86748891

Gene position: 2027529-2026750 (Counterclockwise)

Preceding gene: 86748899

Following gene: 86748890

Centisome position: 38.03

GC content: 70.0

Gene sequence:

>780_bases
ATGGGCCCATTTTCCACCGCACGGGCCCGACCCCGCATCCCGATGACCGCACCCCGCACACTCGTCCTGATCCCCGCGCG
CATGGCCGCGACCAGGCTGCCCGGCAAGCCGCTGCTGGACATCGGCGGCGTGCCGATGGTCGTGCATGTGCTGCGACGCG
CGCTGGCCGCGAACATCGGCCGGGTCGCAGTGGCGACCGATACGCCGGCGATCGCCGACGCCGTCAGAGCCCATGGCGGC
GAGGTGGTGATGACAAGGGCGGATCATCCGTCCGGCTCCGACCGCATTCACGAGGCGCTGCAGACGCTCGATCCGCAGCG
CACGATCGAGACGGTGATCAATCTGCAGGGCGACTTCCCGACCATCCGGCCGGAGCAGATCGGCGCGGTGCTGGCGCCAC
TCGACGATCCGGCGGTCGATATCGCGACGCTGGCCGCCGAGATCCATACCGAGGAAGAAAGCACCAACCCCAACGTGGTG
AAGGTGGTCGGCTCGCACATCGGCACCACCCGGCTGCGCGCGCTGTATTTCACCCGCGCGACCGCGCCGTGGGGCGACGG
GCCGCGCTATCATCATATCGGTCTCTACGCCTATCGCCGCGCCGCGCTGGAGCGCTTCGTGGCGCTGCCGCCCTCGCCGC
TCGAACAGCGCGAGAAACTGGAACAGCTCCGCGCGCTGGAAGCCGGGATGCGGATCGACGTCGGCATCGTCGACAGCGTA
CCGCGCGGCGTCGACACCCCGGCCGATCTGGAGACCGCACGCCGGGTGCTGGCCGGGTGA

Upstream 100 bases:

>100_bases
AGTTGTGATGAGATAACGGTTTGCCCATGCTCTGGCAACCCGTATAAGTGCTTTACACCCCGACGTACCAACAGCCTGAT
ACCGTCCCGATCGAGGCGCG

Downstream 100 bases:

>100_bases
GCCTGCCCACTGGCGAAAAATGCTGCGGCTGCTAGAACGCGCGGCAACACGCAGGAACCCATGACCAAGACCATGAAAAT
CGCATTCCAGGGCGAGCCGG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MGPFSTARARPRIPMTAPRTLVLIPARMAATRLPGKPLLDIGGVPMVVHVLRRALAANIGRVAVATDTPAIADAVRAHGG
EVVMTRADHPSGSDRIHEALQTLDPQRTIETVINLQGDFPTIRPEQIGAVLAPLDDPAVDIATLAAEIHTEEESTNPNVV
KVVGSHIGTTRLRALYFTRATAPWGDGPRYHHIGLYAYRRAALERFVALPPSPLEQREKLEQLRALEAGMRIDVGIVDSV
PRGVDTPADLETARRVLAG

Sequences:

>Translated_259_residues
MGPFSTARARPRIPMTAPRTLVLIPARMAATRLPGKPLLDIGGVPMVVHVLRRALAANIGRVAVATDTPAIADAVRAHGG
EVVMTRADHPSGSDRIHEALQTLDPQRTIETVINLQGDFPTIRPEQIGAVLAPLDDPAVDIATLAAEIHTEEESTNPNVV
KVVGSHIGTTRLRALYFTRATAPWGDGPRYHHIGLYAYRRAALERFVALPPSPLEQREKLEQLRALEAGMRIDVGIVDSV
PRGVDTPADLETARRVLAG
>Mature_258_residues
GPFSTARARPRIPMTAPRTLVLIPARMAATRLPGKPLLDIGGVPMVVHVLRRALAANIGRVAVATDTPAIADAVRAHGGE
VVMTRADHPSGSDRIHEALQTLDPQRTIETVINLQGDFPTIRPEQIGAVLAPLDDPAVDIATLAAEIHTEEESTNPNVVK
VVGSHIGTTRLRALYFTRATAPWGDGPRYHHIGLYAYRRAALERFVALPPSPLEQREKLEQLRALEAGMRIDVGIVDSVP
RGVDTPADLETARRVLAG

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=247, Percent_Identity=47.7732793522267, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27935; Mature: 27803

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPFSTARARPRIPMTAPRTLVLIPARMAATRLPGKPLLDIGGVPMVVHVLRRALAANIG
CCCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
RVAVATDTPAIADAVRAHGGEVVMTRADHPSGSDRIHEALQTLDPQRTIETVINLQGDFP
CEEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCC
TIRPEQIGAVLAPLDDPAVDIATLAAEIHTEEESTNPNVVKVVGSHIGTTRLRALYFTRA
CCCHHHHCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHCCHHHHHHHHEEEC
TAPWGDGPRYHHIGLYAYRRAALERFVALPPSPLEQREKLEQLRALEAGMRIDVGIVDSV
CCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCC
PRGVDTPADLETARRVLAG
CCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GPFSTARARPRIPMTAPRTLVLIPARMAATRLPGKPLLDIGGVPMVVHVLRRALAANIG
CCCCCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
RVAVATDTPAIADAVRAHGGEVVMTRADHPSGSDRIHEALQTLDPQRTIETVINLQGDFP
CEEEECCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCC
TIRPEQIGAVLAPLDDPAVDIATLAAEIHTEEESTNPNVVKVVGSHIGTTRLRALYFTRA
CCCHHHHCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHCCHHHHHHHHEEEC
TAPWGDGPRYHHIGLYAYRRAALERFVALPPSPLEQREKLEQLRALEAGMRIDVGIVDSV
CCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCC
PRGVDTPADLETARRVLAG
CCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA