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The map label for this gene is cysW [H]

Identifier: 86748172

GI number: 86748172

Start: 1203970

End: 1204890

Strand: Direct

Name: cysW [H]

Synonym: RPB_1047

Alternate gene names: 86748172

Gene position: 1203970-1204890 (Clockwise)

Preceding gene: 86748171

Following gene: 86748173

Centisome position: 22.58

GC content: 66.45

Gene sequence:

>921_bases
ATGACGCTGGTCGCGACCACATCCGTGAGGCGCTCCCCGCGCAAGCCTGCCGTCGCGGCCGGCGCACGTGCCGGGCAGCC
GGCGCGGCGCCCGGCGCATGGCGAGCCGGCCTGGGTGCGCCTGCTGATCATCGGCTTCGCCGTGAGTTTTCTCACCGTCT
TCGTGGTGCTGCCGCTGATCCTGGTGTTCTCGGAGGCGCTGTCGAAGGGCGTCTCGTTCTATCTCGACGCGCTGGCGGGA
GACGAAGCGCTGGCGGCGATCCGGCTGACGCTGGTCGCGGCGGCGATCTCGGTCGGGCTCAATCTGGTGTTCGGCGTGAT
CGCCGCCTGGGCGATCGCGAAGTTCGAGTTTCGCGGCAAGACGCTGCTGATCACGCTGATCGATCTGCCGTTCTCGGTCA
GCCCGGTGATCTCCGGCCTGGTATTCGTGCTGCTGTTCGGCGCGCAGGGCTTTGTCGGCCCGTGGCTGATGGCCCACGAC
GTGCGAATCCTGTTCGCGCTGCCGGCGATCGTGCTGGCGACCACCTTCGTGACCTTCCCGTTCGTCGCGCGCGAACTGAT
CCCGCTGATGCAGGAGCAGGGCCAGCACGAGGAAGAAGCCGCGATCTCGCTCGGCGCCAGCGGCTGGAAAACCTTCTGGC
GGGTGACGCTGCCGAACATCAAATGGGGCCTGCTGTACGGCGTGCTGCTGTGCAATGCGCGGGCGATGGGCGAGTTCGGC
GCGGTGTCGGTGGTGTCGGGTCACATCCGCGGCGAGACCAACACCATGCCGCTGCTGGTCGAAATTCTCTACAACGAGTA
TCAGATGGTCGCCGCCTTCGCGATCGCCTCGCTGCTGGCGCTGCTGGCGCTGGTGACGCTGATCGTCAAGACCATCTTGG
AAGGCCGTATCGAGGAAGGGCTGCACACCGATGACCATTGA

Upstream 100 bases:

>100_bases
ATCGCGGTGGTGATGCTGCTCTTCTCCTTCCTGATCATTCTCGTTCTGAACCGGCTGCAGCATTGGGCGCAGACCCGGTC
GCTGGCGGGAGCGTGAGGCG

Downstream 100 bases:

>100_bases
AGTCCGCAACATCGTCAAGCAATTCGGCAGTTTCCGCGCGCTCGACAATGTCGACCTGCGGGTCGAGACCGGCGAGCTGA
TGGCGCTGCTCGGCCCCTCC

Product: sulfate ABC transporter, permease protein CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTLVATTSVRRSPRKPAVAAGARAGQPARRPAHGEPAWVRLLIIGFAVSFLTVFVVLPLILVFSEALSKGVSFYLDALAG
DEALAAIRLTLVAAAISVGLNLVFGVIAAWAIAKFEFRGKTLLITLIDLPFSVSPVISGLVFVLLFGAQGFVGPWLMAHD
VRILFALPAIVLATTFVTFPFVARELIPLMQEQGQHEEEAAISLGASGWKTFWRVTLPNIKWGLLYGVLLCNARAMGEFG
AVSVVSGHIRGETNTMPLLVEILYNEYQMVAAFAIASLLALLALVTLIVKTILEGRIEEGLHTDDH

Sequences:

>Translated_306_residues
MTLVATTSVRRSPRKPAVAAGARAGQPARRPAHGEPAWVRLLIIGFAVSFLTVFVVLPLILVFSEALSKGVSFYLDALAG
DEALAAIRLTLVAAAISVGLNLVFGVIAAWAIAKFEFRGKTLLITLIDLPFSVSPVISGLVFVLLFGAQGFVGPWLMAHD
VRILFALPAIVLATTFVTFPFVARELIPLMQEQGQHEEEAAISLGASGWKTFWRVTLPNIKWGLLYGVLLCNARAMGEFG
AVSVVSGHIRGETNTMPLLVEILYNEYQMVAAFAIASLLALLALVTLIVKTILEGRIEEGLHTDDH
>Mature_305_residues
TLVATTSVRRSPRKPAVAAGARAGQPARRPAHGEPAWVRLLIIGFAVSFLTVFVVLPLILVFSEALSKGVSFYLDALAGD
EALAAIRLTLVAAAISVGLNLVFGVIAAWAIAKFEFRGKTLLITLIDLPFSVSPVISGLVFVLLFGAQGFVGPWLMAHDV
RILFALPAIVLATTFVTFPFVARELIPLMQEQGQHEEEAAISLGASGWKTFWRVTLPNIKWGLLYGVLLCNARAMGEFGA
VSVVSGHIRGETNTMPLLVEILYNEYQMVAAFAIASLLALLALVTLIVKTILEGRIEEGLHTDDH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=262, Percent_Identity=51.5267175572519, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1788764, Length=223, Percent_Identity=35.8744394618834, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786980, Length=178, Percent_Identity=33.1460674157303, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787369, Length=178, Percent_Identity=28.0898876404494, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32942; Mature: 32811

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVATTSVRRSPRKPAVAAGARAGQPARRPAHGEPAWVRLLIIGFAVSFLTVFVVLPLI
CEEEEECHHHCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVFSEALSKGVSFYLDALAGDEALAAIRLTLVAAAISVGLNLVFGVIAAWAIAKFEFRGK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
TLLITLIDLPFSVSPVISGLVFVLLFGAQGFVGPWLMAHDVRILFALPAIVLATTFVTFP
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVARELIPLMQEQGQHEEEAAISLGASGWKTFWRVTLPNIKWGLLYGVLLCNARAMGEFG
HHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHEEEEECCCCHHHHHHHHHHHCCHHCCCCC
AVSVVSGHIRGETNTMPLLVEILYNEYQMVAAFAIASLLALLALVTLIVKTILEGRIEEG
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LHTDDH
CCCCCC
>Mature Secondary Structure 
TLVATTSVRRSPRKPAVAAGARAGQPARRPAHGEPAWVRLLIIGFAVSFLTVFVVLPLI
EEEEECHHHCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LVFSEALSKGVSFYLDALAGDEALAAIRLTLVAAAISVGLNLVFGVIAAWAIAKFEFRGK
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
TLLITLIDLPFSVSPVISGLVFVLLFGAQGFVGPWLMAHDVRILFALPAIVLATTFVTFP
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVARELIPLMQEQGQHEEEAAISLGASGWKTFWRVTLPNIKWGLLYGVLLCNARAMGEFG
HHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHEEEEECCCCHHHHHHHHHHHCCHHCCCCC
AVSVVSGHIRGETNTMPLLVEILYNEYQMVAAFAIASLLALLALVTLIVKTILEGRIEEG
CHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LHTDDH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]