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The map label for this gene is dnaX [H]

Identifier: 86747794

GI number: 86747794

Start: 751755

End: 753638

Strand: Reverse

Name: dnaX [H]

Synonym: RPB_0668

Alternate gene names: 86747794

Gene position: 753638-751755 (Counterclockwise)

Preceding gene: 86747798

Following gene: 86747793

Centisome position: 14.14

GC content: 68.95

Gene sequence:

>1884_bases
ATGACCGACGCAGGCCCTCCCGCGACCCCTTCGGACGATTCGGATCGGACCGGCCTCGCGCCGACTGCAGGCGCCTCGGG
TGGCGCTCCGGCCGGCGCCTATCGGGTGCTGGCGCGTAAGTATCGTCCCAACAGCTTCGAAGACCTGATCGGCCAGGAAG
CGGTGGTGCGCACCGTCTCCAACGCGTTCGATACCGGGCGGATTCCGCAGGCCTGGATCCTCACCGGCGTCCGCGGCGTC
GGCAAGACCACCACGGCGCGCATCCTGGCGCGGGCGCTGAATTACGAGCTGCCGGACGGTTCGGTGAAGGGGCCGACCAT
CCACATGCCGGTGCACGGCGTGCACTGCAAGGCGATCATGGAAAGCCGGCACATGGACGTGCTGGAGATGGACGCCGCCT
CGCATACCGGGGTCGACGACGTCCGCCAGATCAACGACAGCGTGCGCTACGCCCCGGCCAGCGCGCGCTACAAGGTCTAC
ATCATCGACGAAGTCCACATGCTGTCGACGGCGGCGTTCAACGCTTTCCTGAAGACGCTGGAGGAACCGCCGGAGCACGC
CAAATTCGTGTTCGCCACCACCGAGATCCGCAAGGTGCCGGTGACGGTGCTGTCGCGCTGCCAGCGTTTCGATCTGCGCC
GCGTCGAGGCCGACGTGCTGATGAAGCACCTCGGCGGTATAGCCGAGAAAGAAGGCGTCGAGGTCGAGGCCGAAGCGCTC
GGCATCATCGCCCGCGCCGCCGAAGGCTCGGTGCGCGATTCGCTGTCGCTGTTCGATCAGGCGATCGCCCATGCGGCCGG
TCTGGTGCGCGCCGATCAGGTCCGGCAGATGCTCGGCCTCGCCGATCGTACCCGGGTGATCGAGCTGTTCGATGCGCTGG
CGCGCGGCGACATCGCCGCCGCCTTCGCGGAATTCCGCGATCAATACGACACCGGCGCCGATCCGGTGGTGGTGCTGAGC
GATCTCGCCGAATTCGTGAACTTCGTGACGCGGGTCAAGATCGTGCCGGCGACCGCCGACAATGTGGCGTTCGGCGAGAC
CGAGCGGCTGCGCGGGCGCGAATTTGCGACCCGGCTGTCGATGCGGGTGCTGTCGCGGATGTGGCAGATGCTGCTCAAGG
GCATCGCCGAAGTGCAAGGCGCGACGCGCCCCGCCGCAGCCGCCGAAATGGTGCTGGTGCGGATTGCGTACGCGGCCGAT
CTGCCGACGCCGGATGAAGCGATCCGGATGATCGAGCAAGGTGGCGGCGGCGGCGGTTCGCTGCCGTCCGGCGGCAGTGC
GCCGCGTGACGCGCCGTCGGCTCCGCCCTCCGCTCCACCCTCCGCAATGGCATCAGCTCCGCCAAATTACGCTACGCCGG
CCGCAATGGCGCCGCGCGGTGGCGCGACGATGAGCCAGCCGTCGATGGCGCGGCCGCAGCCCGCCGCGGCTCCGCAGCCG
ACCCCCGCGGCGCTGACGATCACAAGTTTCCCGCAGCTCGTCGCGCTCGCGTCGGAAAAGCGCGATGTGATGACCCGGAT
GGCGCTGGAAGCCGATGTTCGGCTGGTGCGGATCGAGGACGGCCGGCTCGAACTGGCGCTGGAGCGCACCGCGTCGCGCA
GCCTGATCGGCGAGCTCGGCCGCAAGCTCGAACAATGGACCGGGCGGCGCTGGACCGTGATCGTGTCGAACGAGCCGGGC
CAGCCGACGCTGCGCTCACAGAACGAGGCGCAGAAGAACGAGCGCGAGCGCGCCGCGGAGAGCGATCCGCGGGTGCAGGA
GGTGCTGGCGCGGTTTCCCGGCGCCAAGGTGATCGAGGTGCGGCGGCTCGCCACCGAGCCGGCCCAGACCGATGCTGGTA
TCGAAGGCGCCGTCGATCCGGTCGACGACGACGACGATTCTTGA

Upstream 100 bases:

>100_bases
AGTGCCGGTGTCGGACGGGTGTCGGGCCGGGTCCCCGCCGGACAGCCTCCGTCCCGTTCCGCAATGCGGCCCCGAGAGAG
AACACATTGCGGAACGCCCG

Downstream 100 bases:

>100_bases
GAATTCTGGCTCTTTCGAGAAGGAACAGATCATGGCTGATTTCCTCGGCATGATGAAACAGGCGGCGCAGCTGCAGTCGA
AGATGAAGGCGATGCAGGCG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MTDAGPPATPSDDSDRTGLAPTAGASGGAPAGAYRVLARKYRPNSFEDLIGQEAVVRTVSNAFDTGRIPQAWILTGVRGV
GKTTTARILARALNYELPDGSVKGPTIHMPVHGVHCKAIMESRHMDVLEMDAASHTGVDDVRQINDSVRYAPASARYKVY
IIDEVHMLSTAAFNAFLKTLEEPPEHAKFVFATTEIRKVPVTVLSRCQRFDLRRVEADVLMKHLGGIAEKEGVEVEAEAL
GIIARAAEGSVRDSLSLFDQAIAHAAGLVRADQVRQMLGLADRTRVIELFDALARGDIAAAFAEFRDQYDTGADPVVVLS
DLAEFVNFVTRVKIVPATADNVAFGETERLRGREFATRLSMRVLSRMWQMLLKGIAEVQGATRPAAAAEMVLVRIAYAAD
LPTPDEAIRMIEQGGGGGGSLPSGGSAPRDAPSAPPSAPPSAMASAPPNYATPAAMAPRGGATMSQPSMARPQPAAAPQP
TPAALTITSFPQLVALASEKRDVMTRMALEADVRLVRIEDGRLELALERTASRSLIGELGRKLEQWTGRRWTVIVSNEPG
QPTLRSQNEAQKNERERAAESDPRVQEVLARFPGAKVIEVRRLATEPAQTDAGIEGAVDPVDDDDDS

Sequences:

>Translated_627_residues
MTDAGPPATPSDDSDRTGLAPTAGASGGAPAGAYRVLARKYRPNSFEDLIGQEAVVRTVSNAFDTGRIPQAWILTGVRGV
GKTTTARILARALNYELPDGSVKGPTIHMPVHGVHCKAIMESRHMDVLEMDAASHTGVDDVRQINDSVRYAPASARYKVY
IIDEVHMLSTAAFNAFLKTLEEPPEHAKFVFATTEIRKVPVTVLSRCQRFDLRRVEADVLMKHLGGIAEKEGVEVEAEAL
GIIARAAEGSVRDSLSLFDQAIAHAAGLVRADQVRQMLGLADRTRVIELFDALARGDIAAAFAEFRDQYDTGADPVVVLS
DLAEFVNFVTRVKIVPATADNVAFGETERLRGREFATRLSMRVLSRMWQMLLKGIAEVQGATRPAAAAEMVLVRIAYAAD
LPTPDEAIRMIEQGGGGGGSLPSGGSAPRDAPSAPPSAPPSAMASAPPNYATPAAMAPRGGATMSQPSMARPQPAAAPQP
TPAALTITSFPQLVALASEKRDVMTRMALEADVRLVRIEDGRLELALERTASRSLIGELGRKLEQWTGRRWTVIVSNEPG
QPTLRSQNEAQKNERERAAESDPRVQEVLARFPGAKVIEVRRLATEPAQTDAGIEGAVDPVDDDDDS
>Mature_626_residues
TDAGPPATPSDDSDRTGLAPTAGASGGAPAGAYRVLARKYRPNSFEDLIGQEAVVRTVSNAFDTGRIPQAWILTGVRGVG
KTTTARILARALNYELPDGSVKGPTIHMPVHGVHCKAIMESRHMDVLEMDAASHTGVDDVRQINDSVRYAPASARYKVYI
IDEVHMLSTAAFNAFLKTLEEPPEHAKFVFATTEIRKVPVTVLSRCQRFDLRRVEADVLMKHLGGIAEKEGVEVEAEALG
IIARAAEGSVRDSLSLFDQAIAHAAGLVRADQVRQMLGLADRTRVIELFDALARGDIAAAFAEFRDQYDTGADPVVVLSD
LAEFVNFVTRVKIVPATADNVAFGETERLRGREFATRLSMRVLSRMWQMLLKGIAEVQGATRPAAAAEMVLVRIAYAADL
PTPDEAIRMIEQGGGGGGSLPSGGSAPRDAPSAPPSAPPSAMASAPPNYATPAAMAPRGGATMSQPSMARPQPAAAPQPT
PAALTITSFPQLVALASEKRDVMTRMALEADVRLVRIEDGRLELALERTASRSLIGELGRKLEQWTGRRWTVIVSNEPGQ
PTLRSQNEAQKNERERAAESDPRVQEVLARFPGAKVIEVRRLATEPAQTDAGIEGAVDPVDDDDDS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=331, Percent_Identity=22.9607250755287, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI31881687, Length=331, Percent_Identity=22.9607250755287, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI6677723, Length=300, Percent_Identity=24, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI194306571, Length=272, Percent_Identity=23.1617647058824, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI194306567, Length=272, Percent_Identity=23.1617647058824, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI31563534, Length=296, Percent_Identity=23.6486486486486, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1786676, Length=377, Percent_Identity=41.1140583554377, Blast_Score=267, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17541988, Length=238, Percent_Identity=26.4705882352941, Blast_Score=69, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324478, Length=245, Percent_Identity=25.7142857142857, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324039, Length=227, Percent_Identity=25.9911894273128, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322528, Length=319, Percent_Identity=22.884012539185, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17647857, Length=288, Percent_Identity=24.6527777777778, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 67266; Mature: 67135

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAGPPATPSDDSDRTGLAPTAGASGGAPAGAYRVLARKYRPNSFEDLIGQEAVVRTVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NAFDTGRIPQAWILTGVRGVGKTTTARILARALNYELPDGSVKGPTIHMPVHGVHCKAIM
HHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHH
ESRHMDVLEMDAASHTGVDDVRQINDSVRYAPASARYKVYIIDEVHMLSTAAFNAFLKTL
HHCCCCCEEECCCCCCCHHHHHHHHHHHEECCCCCCEEEEEECCHHHHHHHHHHHHHHHH
EEPPEHAKFVFATTEIRKVPVTVLSRCQRFDLRRVEADVLMKHLGGIAEKEGVEVEAEAL
HCCCCCCEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEHHHH
GIIARAAEGSVRDSLSLFDQAIAHAAGLVRADQVRQMLGLADRTRVIELFDALARGDIAA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AFAEFRDQYDTGADPVVVLSDLAEFVNFVTRVKIVPATADNVAFGETERLRGREFATRLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHH
MRVLSRMWQMLLKGIAEVQGATRPAAAAEMVLVRIAYAADLPTPDEAIRMIEQGGGGGGS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
LPSGGSAPRDAPSAPPSAPPSAMASAPPNYATPAAMAPRGGATMSQPSMARPQPAAAPQP
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPAALTITSFPQLVALASEKRDVMTRMALEADVRLVRIEDGRLELALERTASRSLIGELG
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEEHHHHHHHHHHHHHH
RKLEQWTGRRWTVIVSNEPGQPTLRSQNEAQKNERERAAESDPRVQEVLARFPGAKVIEV
HHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHH
RRLATEPAQTDAGIEGAVDPVDDDDDS
HHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDAGPPATPSDDSDRTGLAPTAGASGGAPAGAYRVLARKYRPNSFEDLIGQEAVVRTVS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NAFDTGRIPQAWILTGVRGVGKTTTARILARALNYELPDGSVKGPTIHMPVHGVHCKAIM
HHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHH
ESRHMDVLEMDAASHTGVDDVRQINDSVRYAPASARYKVYIIDEVHMLSTAAFNAFLKTL
HHCCCCCEEECCCCCCCHHHHHHHHHHHEECCCCCCEEEEEECCHHHHHHHHHHHHHHHH
EEPPEHAKFVFATTEIRKVPVTVLSRCQRFDLRRVEADVLMKHLGGIAEKEGVEVEAEAL
HCCCCCCEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCEEEHHHH
GIIARAAEGSVRDSLSLFDQAIAHAAGLVRADQVRQMLGLADRTRVIELFDALARGDIAA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
AFAEFRDQYDTGADPVVVLSDLAEFVNFVTRVKIVPATADNVAFGETERLRGREFATRLS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHH
MRVLSRMWQMLLKGIAEVQGATRPAAAAEMVLVRIAYAADLPTPDEAIRMIEQGGGGGGS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
LPSGGSAPRDAPSAPPSAPPSAMASAPPNYATPAAMAPRGGATMSQPSMARPQPAAAPQP
CCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPAALTITSFPQLVALASEKRDVMTRMALEADVRLVRIEDGRLELALERTASRSLIGELG
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEEHHHHHHHHHHHHHH
RKLEQWTGRRWTVIVSNEPGQPTLRSQNEAQKNERERAAESDPRVQEVLARFPGAKVIEV
HHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHH
RRLATEPAQTDAGIEGAVDPVDDDDDS
HHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]