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The map label for this gene is moeZ [H]

Identifier: 86747743

GI number: 86747743

Start: 695453

End: 696250

Strand: Reverse

Name: moeZ [H]

Synonym: RPB_0617

Alternate gene names: 86747743

Gene position: 696250-695453 (Counterclockwise)

Preceding gene: 86747745

Following gene: 86747741

Centisome position: 13.06

GC content: 68.92

Gene sequence:

>798_bases
ATGCTGAGCGCCGAGGAACTCGAACGCTATGCCCGCCATATCGTGCTGCGCGAGGTCGGCGGGCCGGGGCAGGCGGCGCT
GCGGCGCGCGCGGGTGCTGGTGGTCGGCGCCGGCGGGCTCGGCGCGCCGGTGCTGATGTATCTGGCCGCCGCCGGCGTCG
GCACGCTGCACATCGTCGACGACGATGTGGTGTCGCTGTCGAATTTGCAGCGCCAGGTGATCCACGCCACGCCGGATGTC
GGCGCTCGCAAGGTCGACAGCGCGGCGGCGCGAATTCATGCGCTCAATCCGCATGTGCAGGTGGTGCCGCATCCGACGCA
TCTCACCTCCGCGAATGCGCTGGGGCTGATCGGCGATTGCGACCTGGTGCTCGACGGCTCGGACAATTTCGCCACGCGCT
ATCTGGTGTCGGACGCCTGCTTCATCGCAAAGAAGCCGCTGATCACCGCGGCGCTCGGCCAATTCGACGGCTCGCTGACC
ACGATCCGGGCGCATGAGAAAAATGCGCAGGGCGAGCCCAACCCGACCTATCGCTGCCTGTTTCCGGAAGCGCCGCCGCC
CGGCACGGTGCCGGCCTGCGAGGAGGCCGGCGTGATGGGCGCGCTCGCCGGCCTGCTCGGCTCGATGATGGCGCTGGAGG
CGATCCGCGAAATCGTCGGCTTCGGCGAGGGGCTGGTCGGGCGGCTGCTGATGATCGACGCCCGCGCGATGCGATTCGAG
ACGCTGCGCTATGCGCGCGATCCGGCCAATCCGCTGAACGGGGATATGGCGCGCATCGTCGATCTCAGCGCGCATTGA

Upstream 100 bases:

>100_bases
CCCCGGCTTCGCCCTGTCGGGCTTCGCCGCGGCTCCTCAGGATGACGAGGTGGGCGCGGAAACGAAGACGACGACAGACG
TTGAAGGACACCACCCGACC

Downstream 100 bases:

>100_bases
GGGGACGGTATTGCGGACTCACTGCCCGCGTCGCCCTCACCCCAGCCCTCTCCCGCAGGCGGGAGAGGGAGTCCGGCCGC
ATGCGGTTCGAATGGTTTTG

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLSAEELERYARHIVLREVGGPGQAALRRARVLVVGAGGLGAPVLMYLAAAGVGTLHIVDDDVVSLSNLQRQVIHATPDV
GARKVDSAAARIHALNPHVQVVPHPTHLTSANALGLIGDCDLVLDGSDNFATRYLVSDACFIAKKPLITAALGQFDGSLT
TIRAHEKNAQGEPNPTYRCLFPEAPPPGTVPACEEAGVMGALAGLLGSMMALEAIREIVGFGEGLVGRLLMIDARAMRFE
TLRYARDPANPLNGDMARIVDLSAH

Sequences:

>Translated_265_residues
MLSAEELERYARHIVLREVGGPGQAALRRARVLVVGAGGLGAPVLMYLAAAGVGTLHIVDDDVVSLSNLQRQVIHATPDV
GARKVDSAAARIHALNPHVQVVPHPTHLTSANALGLIGDCDLVLDGSDNFATRYLVSDACFIAKKPLITAALGQFDGSLT
TIRAHEKNAQGEPNPTYRCLFPEAPPPGTVPACEEAGVMGALAGLLGSMMALEAIREIVGFGEGLVGRLLMIDARAMRFE
TLRYARDPANPLNGDMARIVDLSAH
>Mature_265_residues
MLSAEELERYARHIVLREVGGPGQAALRRARVLVVGAGGLGAPVLMYLAAAGVGTLHIVDDDVVSLSNLQRQVIHATPDV
GARKVDSAAARIHALNPHVQVVPHPTHLTSANALGLIGDCDLVLDGSDNFATRYLVSDACFIAKKPLITAALGQFDGSLT
TIRAHEKNAQGEPNPTYRCLFPEAPPPGTVPACEEAGVMGALAGLLGSMMALEAIREIVGFGEGLVGRLLMIDARAMRFE
TLRYARDPANPLNGDMARIVDLSAH

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=233, Percent_Identity=46.7811158798283, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI4885649, Length=154, Percent_Identity=31.8181818181818, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI38045948, Length=166, Percent_Identity=34.9397590361446, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38045942, Length=89, Percent_Identity=38.2022471910112, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI38045944, Length=89, Percent_Identity=38.2022471910112, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787048, Length=256, Percent_Identity=41.796875, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI87082356, Length=253, Percent_Identity=37.1541501976285, Blast_Score=144, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI17540406, Length=255, Percent_Identity=40.3921568627451, Blast_Score=195, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI193203301, Length=156, Percent_Identity=27.5641025641026, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=220, Percent_Identity=45, Blast_Score=189, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6320598, Length=177, Percent_Identity=28.8135593220339, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325323, Length=173, Percent_Identity=28.3236994219653, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582879, Length=242, Percent_Identity=43.801652892562, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24660640, Length=141, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI20129973, Length=109, Percent_Identity=36.697247706422, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27961; Mature: 27961

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAEELERYARHIVLREVGGPGQAALRRARVLVVGAGGLGAPVLMYLAAAGVGTLHIVD
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHCCCCEEEEEC
DDVVSLSNLQRQVIHATPDVGARKVDSAAARIHALNPHVQVVPHPTHLTSANALGLIGDC
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCEEEEECC
DLVLDGSDNFATRYLVSDACFIAKKPLITAALGQFDGSLTTIRAHEKNAQGEPNPTYRCL
EEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEE
FPEAPPPGTVPACEEAGVMGALAGLLGSMMALEAIREIVGFGEGLVGRLLMIDARAMRFE
CCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TLRYARDPANPLNGDMARIVDLSAH
HHHHHCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MLSAEELERYARHIVLREVGGPGQAALRRARVLVVGAGGLGAPVLMYLAAAGVGTLHIVD
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHEEEEEEECCCCHHHHHHHHHHCCCCEEEEEC
DDVVSLSNLQRQVIHATPDVGARKVDSAAARIHALNPHVQVVPHPTHLTSANALGLIGDC
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEECCCCEEEEECCCCCCCCCCEEEEECC
DLVLDGSDNFATRYLVSDACFIAKKPLITAALGQFDGSLTTIRAHEKNAQGEPNPTYRCL
EEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEE
FPEAPPPGTVPACEEAGVMGALAGLLGSMMALEAIREIVGFGEGLVGRLLMIDARAMRFE
CCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TLRYARDPANPLNGDMARIVDLSAH
HHHHHCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]