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The map label for this gene is mmgC [H]

Identifier: 86747684

GI number: 86747684

Start: 628346

End: 629506

Strand: Reverse

Name: mmgC [H]

Synonym: RPB_0558

Alternate gene names: 86747684

Gene position: 629506-628346 (Counterclockwise)

Preceding gene: 86747685

Following gene: 86747683

Centisome position: 11.81

GC content: 66.75

Gene sequence:

>1161_bases
ATGACCGCCGCCCTCCGTTTCGATCCGATCCGCCTGCCGCCCGTCTGCGAGGAGCTGCGCCGCGAAGTGCGCGCGTTCCT
CGCCGAGGAAATCGCCGCCGGCACCTTCGATCCGCACAAGCCGCAGCGTGAAGACTCCGACGCGCCGGAATTCTCCCGCC
GCGTCGGCGCGCGCGGCTGGCTCGGCATGACCTGGCCCAAGCAATATGGCGGGCACGAACGCACGTTTCTCGAGCGCTAC
GTCGTCACCGAGGAGATGCGCGTTGCGAATGCGCCGACCCGGCGGTTCTTCGTCGCCGACCGCCAGAGCGGCCCTGTGCT
GTTGAAATACGCGCCCGAGCACATCAAGATGGACATCCTGCCGCGGATCTGCCGCGGCGAATTGTGCTTCGCGATCGGCA
TGAGCGAGCCGAATTCCGGCTCCGACCTGTTCGCCGCCAAGACCAAGGCGACCAGGACCGACGGCGGCTATCTGATCAAC
GGCGCCAAGATCTGGACCACCTCGGCCCACATGGCCGACTACATGATCGCGATCTTCCGCACCTCGCCGCCCACCAAGGA
GAACCGCCGCCACGGCCTGACGCAGTTTCTGGTCGACATGAAATCGCCCGGCATCAAGGTCAATCCGATCGGGCAGATCA
CCGGCCAGCACGAATTCAACGAGGTGGTGTTCACCGACGCCTTCGTGCCGGACGATCATCTGCTCGGCGAGATCGACGGC
GCGTGGAAACAGGCGACCTCCGAACTCGCTTACGAGCGCTCCGGGCCGGAACGGTTTCTCGAAACCTCCTACGTGCTGAT
CGAACTGGTGCGCGCGCTCGGCCCCGATCCGGACACGCGCGGCGCCGAGGGGATCGGCCGGCTGGTGGCGCAGCTCCACA
CCATGCGGCGGATGTCGGTGTCGGTCGCCGGCATGCTGCAGGCCGGCAAGGAGCCGGTGGTGGAAGCCTCGATCGTCAAG
GACATCGGCACGCTGTGGGAGCAGCAACTGCCGCACCGCGTGCGCGAACTCGCGGCGTTCGTCGACGCGGACGATTCCAA
CCACGCCACGCTCGACGAACTCACCGCCTTCGCCACCAAACTGGCGCCCAAACTCACGATTCAGGGTGGCACCACCGAGG
TGCTGCGCGGCATCATCGCGCGCGGACTCGGCCTGCGCTGA

Upstream 100 bases:

>100_bases
GGCGGTCGCGCTCGGCCGCATGGTGGCGGCGCGCGGCGCCGACGATCTGTGGCCGCTGGTCGCCTCGCGCTGATCGCCCC
GAAACCCGACGAGACACATC

Downstream 100 bases:

>100_bases
GCCGCGCGCCCAAAGATCAAGGAACACGTCATGACCACCAAGGATATTGCCGTCGAAGTCACCGGCCACGTCGCGCTGAT
CGAGATCCGGCGGCCGCCGC

Product: Acyl-CoA dehydrogenase-like

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTAALRFDPIRLPPVCEELRREVRAFLAEEIAAGTFDPHKPQREDSDAPEFSRRVGARGWLGMTWPKQYGGHERTFLERY
VVTEEMRVANAPTRRFFVADRQSGPVLLKYAPEHIKMDILPRICRGELCFAIGMSEPNSGSDLFAAKTKATRTDGGYLIN
GAKIWTTSAHMADYMIAIFRTSPPTKENRRHGLTQFLVDMKSPGIKVNPIGQITGQHEFNEVVFTDAFVPDDHLLGEIDG
AWKQATSELAYERSGPERFLETSYVLIELVRALGPDPDTRGAEGIGRLVAQLHTMRRMSVSVAGMLQAGKEPVVEASIVK
DIGTLWEQQLPHRVRELAAFVDADDSNHATLDELTAFATKLAPKLTIQGGTTEVLRGIIARGLGLR

Sequences:

>Translated_386_residues
MTAALRFDPIRLPPVCEELRREVRAFLAEEIAAGTFDPHKPQREDSDAPEFSRRVGARGWLGMTWPKQYGGHERTFLERY
VVTEEMRVANAPTRRFFVADRQSGPVLLKYAPEHIKMDILPRICRGELCFAIGMSEPNSGSDLFAAKTKATRTDGGYLIN
GAKIWTTSAHMADYMIAIFRTSPPTKENRRHGLTQFLVDMKSPGIKVNPIGQITGQHEFNEVVFTDAFVPDDHLLGEIDG
AWKQATSELAYERSGPERFLETSYVLIELVRALGPDPDTRGAEGIGRLVAQLHTMRRMSVSVAGMLQAGKEPVVEASIVK
DIGTLWEQQLPHRVRELAAFVDADDSNHATLDELTAFATKLAPKLTIQGGTTEVLRGIIARGLGLR
>Mature_385_residues
TAALRFDPIRLPPVCEELRREVRAFLAEEIAAGTFDPHKPQREDSDAPEFSRRVGARGWLGMTWPKQYGGHERTFLERYV
VTEEMRVANAPTRRFFVADRQSGPVLLKYAPEHIKMDILPRICRGELCFAIGMSEPNSGSDLFAAKTKATRTDGGYLING
AKIWTTSAHMADYMIAIFRTSPPTKENRRHGLTQFLVDMKSPGIKVNPIGQITGQHEFNEVVFTDAFVPDDHLLGEIDGA
WKQATSELAYERSGPERFLETSYVLIELVRALGPDPDTRGAEGIGRLVAQLHTMRRMSVSVAGMLQAGKEPVVEASIVKD
IGTLWEQQLPHRVRELAAFVDADDSNHATLDELTAFATKLAPKLTIQGGTTEVLRGIIARGLGLR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=384, Percent_Identity=26.0416666666667, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI226958414, Length=352, Percent_Identity=26.4204545454545, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI4501859, Length=320, Percent_Identity=25.9375, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4501857, Length=408, Percent_Identity=24.2647058823529, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4557233, Length=209, Percent_Identity=29.1866028708134, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI187960098, Length=185, Percent_Identity=25.4054054054054, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4557231, Length=185, Percent_Identity=25.4054054054054, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI21361497, Length=335, Percent_Identity=25.0746268656716, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=191, Percent_Identity=27.2251308900524, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786223, Length=212, Percent_Identity=25.9433962264151, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=238, Percent_Identity=27.7310924369748, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=246, Percent_Identity=28.8617886178862, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=231, Percent_Identity=26.4069264069264, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=193, Percent_Identity=29.5336787564767, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=203, Percent_Identity=30.5418719211823, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=208, Percent_Identity=27.8846153846154, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=189, Percent_Identity=24.8677248677249, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=201, Percent_Identity=26.3681592039801, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=209, Percent_Identity=25.8373205741627, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=189, Percent_Identity=24.3386243386243, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=203, Percent_Identity=24.6305418719212, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355753, Length=210, Percent_Identity=30, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24666513, Length=244, Percent_Identity=27.0491803278689, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21356377, Length=243, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24646207, Length=239, Percent_Identity=26.7782426778243, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42908; Mature: 42776

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALRFDPIRLPPVCEELRREVRAFLAEEIAAGTFDPHKPQREDSDAPEFSRRVGARGW
CCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCC
LGMTWPKQYGGHERTFLERYVVTEEMRVANAPTRRFFVADRQSGPVLLKYAPEHIKMDIL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCHHHHHHH
PRICRGELCFAIGMSEPNSGSDLFAAKTKATRTDGGYLINGAKIWTTSAHMADYMIAIFR
HHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCEEEECCEEEECHHHHHHHHHHEEE
TSPPTKENRRHGLTQFLVDMKSPGIKVNPIGQITGQHEFNEVVFTDAFVPDDHLLGEIDG
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCH
AWKQATSELAYERSGPERFLETSYVLIELVRALGPDPDTRGAEGIGRLVAQLHTMRRMSV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVAGMLQAGKEPVVEASIVKDIGTLWEQQLPHRVRELAAFVDADDSNHATLDELTAFATK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LAPKLTIQGGTTEVLRGIIARGLGLR
HCCEEEECCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TAALRFDPIRLPPVCEELRREVRAFLAEEIAAGTFDPHKPQREDSDAPEFSRRVGARGW
CCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCC
LGMTWPKQYGGHERTFLERYVVTEEMRVANAPTRRFFVADRQSGPVLLKYAPEHIKMDIL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCHHHHHHH
PRICRGELCFAIGMSEPNSGSDLFAAKTKATRTDGGYLINGAKIWTTSAHMADYMIAIFR
HHHHCCCEEEEEECCCCCCCCCEEEECCCCCCCCCCEEEECCEEEECHHHHHHHHHHEEE
TSPPTKENRRHGLTQFLVDMKSPGIKVNPIGQITGQHEFNEVVFTDAFVPDDHLLGEIDG
CCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCH
AWKQATSELAYERSGPERFLETSYVLIELVRALGPDPDTRGAEGIGRLVAQLHTMRRMSV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVAGMLQAGKEPVVEASIVKDIGTLWEQQLPHRVRELAAFVDADDSNHATLDELTAFATK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
LAPKLTIQGGTTEVLRGIIARGLGLR
HCCEEEECCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]