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The map label for this gene is yciR [C]

Identifier: 86747317

GI number: 86747317

Start: 212254

End: 214485

Strand: Reverse

Name: yciR [C]

Synonym: RPB_0191

Alternate gene names: 86747317

Gene position: 214485-212254 (Counterclockwise)

Preceding gene: 86747318

Following gene: 86747314

Centisome position: 4.02

GC content: 61.16

Gene sequence:

>2232_bases
ATGATCTCAGCCCCGCTTCCGGACAACGAGCAGGCGCGGCTCACCGCGCTGCGCCGATATGATATTCTTGATACCCCGTC
GGAGGATTGTTTCGACATATTCCCTCGGCTGGTCGTCCGGGCGATCGGCGTCCCCTCGGCCGTGATCAGCTTTGTCGACA
GCGAGCGTCAATGGTTCAAGGCCCGGATCAACGTCACCGACCAACAGACACCGCGCGATATAGCGTTCTGCGCGCACGCG
ATCCTTCGTGATCGCCCGCTCGTGGTTGCGGATGCGACGATCGATCCGCGATTCCACGACAACCCGCTGGTAACCGCATC
AGGCGGCGTGCGGTTCTACGCAGGTGCCCCGATACGAACCGCGGAGGGCTTTGCCATCGGCGTGCTCTGTGCGATCGACA
AGGTCCCCCGCCTCCTTGGAAAAGCGCAACTGGAAACGCTCCGAGAGCTGGCATCGTTGGTCGCCGACCAACTCGATTTG
CGACTGGCGAATCGACGTCTCGCCCGCGAAGTCGCCGAACGCGAACGCACCGAGAACCATCTGCGGTCGATGAGCCGAAC
GCTGGAGCTGTCGAACCTGCGCCTGGATGCGGCGCTCAACAACTTCCTCCATGGGCTGTGCATGTTCGATGGCGACCGCA
AGGTGGTGGTGTCGAATGCACGCTTCGCCGGAATCTACTCTCTCAGACCCGACGAAATCCGGTGCGGCGTTTCTTTGAGC
GCGATCCAGTCGGCGTGCCGAGAACGCGGGACGTTCGTGGAAAGCTGGTCGGAACGCAGGCTTGGTCGATGTTCGGACGA
CATCTCCGAAGTGAGTTCGCTGCAAGACGGGCGGACGATCCTGGTGCGCTGTCAACCGGTCGCAGGTGGCGGCTGGATGA
CCGTGCACGAGGACATCACAGAGCGCTATCGCAGCGAACAGCAAATCGCCCATATGGCCCGCCACGATCTGCTGACCGGC
CTGCTCAATCGCGGAGCCTTCCACGAAAGGATGGATGAGGCCTGTGCACGCCTGCGCCGCTGGGGTGAGACCTTCTCGGT
CATCATGCTGGACCTGGACCGCTTCAAGCTCGTCAACGATTCGCTCGGACATCCGGCGGGGGATGCCCTGCTACGCGCGG
TGGTCTCGCGGCTGAAGGCGTGCATTCGCGAAACGGATGTTCTGGCGCGGCTCGGTGGGGACGAATTCGCCGTGCTGCAG
ACAAGGACGAAAGACTCGTACAACGAGGCGGTGGCCTTCGCGGACCGGATCGTCAATTGCCTGATCGATCCGATCGAGAT
CGACGGGCATCAGCTCGTCATCAGCACCAGCGCGGGAATCGCGCTGGCCCCCCAACACGGCACGGATTCCGACGAGTTGA
TCAAAAATGCCGACCTCGCGCTCTATCGAGCCAAGGCGGCTGGCCGCAACGGATACGTCACCTTCGAAACCGCGATGAAG
GACCGTGCCAATGCGCGCCAGCAACTGGAAGGAGAATTGCGACAAGCCATTCTGAATCGAGAGTTCGATTTGTACTATCA
GCCACAGGTCGAAGCCAGGTCCGGGAGAGTGATCGGCGCGGAGGCGCTGCTACGCTGGCGCCACCCGAGGCGAGGCTTCG
TGCCGCCGTCCGAGTTCATTCCGGTCGCGGAGGAAACCGGCCTGATCGAAAAGCTCGGCGAATGGGTCCTAAAGGAGGCT
GCCGCCGAGGCCATTCGCTGGCCGGCCCCCATCAAGCTCGCGATCAATCTCTCTCCGGTCCAGTTGAGTCGCGGCAACTT
GACCGACACTGTGACGCAAGCTCTGCGACTTTCGGGGCTGCCTCCAGAGCGCTTGGAGGTGGAGATCACGGAAAACGTGT
TTCTAGAGGACGAAGTCAACAACCTCGCCGTCATTAGACAGCTGCGGTCCCTCGGGGTATCCGTGGCCCTGGACGACTTT
GGGACAGGATATTCGTCGCTCAGCTATTTAACGAGATTTCCGTTCGATCAAATCAAAATCGACAAATTTTTCAGCATGAA
TCTGATCGAGCGAAGCGACTGCGCCACAATCGTCTCCTCGGTGATAACTCTGGCGCGAGGCTTGGGGATCTCCACCGTCG
CCGAAGGCGTCGAAACAGTGCGTCAGTTCGAACTGCTGCGGGAGGCGGGCGTCGACTACTTCCAGGGATATCTGTTCGGT
CACCCAGTTCCGGCTTCGGCGCTCAATTTCGGTGCCGCTCACGACATCACGCGCATCACGGAGGTCGCCTGA

Upstream 100 bases:

>100_bases
TGTCGACCGTCGTCGGATATTTGATAAGCCGAGGTGTCGAGATGTCGCTAGATAGCCGCTCAAACTGCCGCACTCTCATC
GCGTGTACTGGAACGCGGCC

Downstream 100 bases:

>100_bases
CAATGATTCGATGTTTGCCGTTGCATGGACTGAAGCGCCGAGTTGAGGACGATTATACGCCCATTGCGGCTCCCCCGGAA
ACCGCCGATGACTGCCATTG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 743; Mature: 743

Protein sequence:

>743_residues
MISAPLPDNEQARLTALRRYDILDTPSEDCFDIFPRLVVRAIGVPSAVISFVDSERQWFKARINVTDQQTPRDIAFCAHA
ILRDRPLVVADATIDPRFHDNPLVTASGGVRFYAGAPIRTAEGFAIGVLCAIDKVPRLLGKAQLETLRELASLVADQLDL
RLANRRLAREVAERERTENHLRSMSRTLELSNLRLDAALNNFLHGLCMFDGDRKVVVSNARFAGIYSLRPDEIRCGVSLS
AIQSACRERGTFVESWSERRLGRCSDDISEVSSLQDGRTILVRCQPVAGGGWMTVHEDITERYRSEQQIAHMARHDLLTG
LLNRGAFHERMDEACARLRRWGETFSVIMLDLDRFKLVNDSLGHPAGDALLRAVVSRLKACIRETDVLARLGGDEFAVLQ
TRTKDSYNEAVAFADRIVNCLIDPIEIDGHQLVISTSAGIALAPQHGTDSDELIKNADLALYRAKAAGRNGYVTFETAMK
DRANARQQLEGELRQAILNREFDLYYQPQVEARSGRVIGAEALLRWRHPRRGFVPPSEFIPVAEETGLIEKLGEWVLKEA
AAEAIRWPAPIKLAINLSPVQLSRGNLTDTVTQALRLSGLPPERLEVEITENVFLEDEVNNLAVIRQLRSLGVSVALDDF
GTGYSSLSYLTRFPFDQIKIDKFFSMNLIERSDCATIVSSVITLARGLGISTVAEGVETVRQFELLREAGVDYFQGYLFG
HPVPASALNFGAAHDITRITEVA

Sequences:

>Translated_743_residues
MISAPLPDNEQARLTALRRYDILDTPSEDCFDIFPRLVVRAIGVPSAVISFVDSERQWFKARINVTDQQTPRDIAFCAHA
ILRDRPLVVADATIDPRFHDNPLVTASGGVRFYAGAPIRTAEGFAIGVLCAIDKVPRLLGKAQLETLRELASLVADQLDL
RLANRRLAREVAERERTENHLRSMSRTLELSNLRLDAALNNFLHGLCMFDGDRKVVVSNARFAGIYSLRPDEIRCGVSLS
AIQSACRERGTFVESWSERRLGRCSDDISEVSSLQDGRTILVRCQPVAGGGWMTVHEDITERYRSEQQIAHMARHDLLTG
LLNRGAFHERMDEACARLRRWGETFSVIMLDLDRFKLVNDSLGHPAGDALLRAVVSRLKACIRETDVLARLGGDEFAVLQ
TRTKDSYNEAVAFADRIVNCLIDPIEIDGHQLVISTSAGIALAPQHGTDSDELIKNADLALYRAKAAGRNGYVTFETAMK
DRANARQQLEGELRQAILNREFDLYYQPQVEARSGRVIGAEALLRWRHPRRGFVPPSEFIPVAEETGLIEKLGEWVLKEA
AAEAIRWPAPIKLAINLSPVQLSRGNLTDTVTQALRLSGLPPERLEVEITENVFLEDEVNNLAVIRQLRSLGVSVALDDF
GTGYSSLSYLTRFPFDQIKIDKFFSMNLIERSDCATIVSSVITLARGLGISTVAEGVETVRQFELLREAGVDYFQGYLFG
HPVPASALNFGAAHDITRITEVA
>Mature_743_residues
MISAPLPDNEQARLTALRRYDILDTPSEDCFDIFPRLVVRAIGVPSAVISFVDSERQWFKARINVTDQQTPRDIAFCAHA
ILRDRPLVVADATIDPRFHDNPLVTASGGVRFYAGAPIRTAEGFAIGVLCAIDKVPRLLGKAQLETLRELASLVADQLDL
RLANRRLAREVAERERTENHLRSMSRTLELSNLRLDAALNNFLHGLCMFDGDRKVVVSNARFAGIYSLRPDEIRCGVSLS
AIQSACRERGTFVESWSERRLGRCSDDISEVSSLQDGRTILVRCQPVAGGGWMTVHEDITERYRSEQQIAHMARHDLLTG
LLNRGAFHERMDEACARLRRWGETFSVIMLDLDRFKLVNDSLGHPAGDALLRAVVSRLKACIRETDVLARLGGDEFAVLQ
TRTKDSYNEAVAFADRIVNCLIDPIEIDGHQLVISTSAGIALAPQHGTDSDELIKNADLALYRAKAAGRNGYVTFETAMK
DRANARQQLEGELRQAILNREFDLYYQPQVEARSGRVIGAEALLRWRHPRRGFVPPSEFIPVAEETGLIEKLGEWVLKEA
AAEAIRWPAPIKLAINLSPVQLSRGNLTDTVTQALRLSGLPPERLEVEITENVFLEDEVNNLAVIRQLRSLGVSVALDDF
GTGYSSLSYLTRFPFDQIKIDKFFSMNLIERSDCATIVSSVITLARGLGISTVAEGVETVRQFELLREAGVDYFQGYLFG
HPVPASALNFGAAHDITRITEVA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=434, Percent_Identity=39.1705069124424, Blast_Score=305, Evalue=9e-84,
Organism=Escherichia coli, GI87081921, Length=435, Percent_Identity=34.9425287356322, Blast_Score=255, Evalue=9e-69,
Organism=Escherichia coli, GI226510982, Length=437, Percent_Identity=29.0617848970252, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87081980, Length=241, Percent_Identity=38.5892116182573, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1788502, Length=240, Percent_Identity=38.3333333333333, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=35.9504132231405, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=35.4430379746835, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87081743, Length=235, Percent_Identity=34.8936170212766, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI87081845, Length=241, Percent_Identity=37.344398340249, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=36.5145228215768, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1788381, Length=497, Percent_Identity=27.1629778672032, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788849, Length=260, Percent_Identity=32.6923076923077, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI87081881, Length=206, Percent_Identity=36.4077669902913, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87082096, Length=255, Percent_Identity=30.1960784313725, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1786584, Length=182, Percent_Identity=33.5164835164835, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI87082007, Length=183, Percent_Identity=33.879781420765, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787262, Length=175, Percent_Identity=34.2857142857143, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI145693134, Length=163, Percent_Identity=36.8098159509202, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1787410, Length=151, Percent_Identity=33.112582781457, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1789650, Length=425, Percent_Identity=23.5294117647059, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081977, Length=151, Percent_Identity=32.4503311258278, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=33.1288343558282, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=36.25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=27.810650887574, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081974, Length=98, Percent_Identity=32.6530612244898, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT; PF00989 PAS [H]

EC number: NA

Molecular weight: Translated: 82671; Mature: 82671

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAPLPDNEQARLTALRRYDILDTPSEDCFDIFPRLVVRAIGVPSAVISFVDSERQWFK
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARINVTDQQTPRDIAFCAHAILRDRPLVVADATIDPRFHDNPLVTASGGVRFYAGAPIRT
HEECCCCCCCCHHHHHHHHHHHCCCCEEEEECEECCCCCCCCEEEECCCEEEEECCCCCC
AEGFAIGVLCAIDKVPRLLGKAQLETLRELASLVADQLDLRLANRRLAREVAERERTENH
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSMSRTLELSNLRLDAALNNFLHGLCMFDGDRKVVVSNARFAGIYSLRPDEIRCGVSLS
HHHHHHHHHHHHEEHHHHHHHHHHHHHEECCCCEEEEECCCEEEEECCCCCHHCCCCCHH
AIQSACRERGTFVESWSERRLGRCSDDISEVSSLQDGRTILVRCQPVAGGGWMTVHEDIT
HHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCEEEHHHHH
ERYRSEQQIAHMARHDLLTGLLNRGAFHERMDEACARLRRWGETFSVIMLDLDRFKLVND
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHEEEEEEHHHHHHHHH
SLGHPAGDALLRAVVSRLKACIRETDVLARLGGDEFAVLQTRTKDSYNEAVAFADRIVNC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LIDPIEIDGHQLVISTSAGIALAPQHGTDSDELIKNADLALYRAKAAGRNGYVTFETAMK
HCCCEEECCCEEEEEECCCEEECCCCCCCHHHHHHCCCHHEEEHHCCCCCCCEEEHHHHH
DRANARQQLEGELRQAILNREFDLYYQPQVEARSGRVIGAEALLRWRHPRRGFVPPSEFI
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEECHHHHHHHCCCCCCCCCCHHCC
PVAEETGLIEKLGEWVLKEAAAEAIRWPAPIKLAINLSPVQLSRGNLTDTVTQALRLSGL
CCHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCC
PPERLEVEITENVFLEDEVNNLAVIRQLRSLGVSVALDDFGTGYSSLSYLTRFPFDQIKI
CCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCEEH
DKFFSMNLIERSDCATIVSSVITLARGLGISTVAEGVETVRQFELLREAGVDYFQGYLFG
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
HPVPASALNFGAAHDITRITEVA
CCCCHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MISAPLPDNEQARLTALRRYDILDTPSEDCFDIFPRLVVRAIGVPSAVISFVDSERQWFK
CCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ARINVTDQQTPRDIAFCAHAILRDRPLVVADATIDPRFHDNPLVTASGGVRFYAGAPIRT
HEECCCCCCCCHHHHHHHHHHHCCCCEEEEECEECCCCCCCCEEEECCCEEEEECCCCCC
AEGFAIGVLCAIDKVPRLLGKAQLETLRELASLVADQLDLRLANRRLAREVAERERTENH
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRSMSRTLELSNLRLDAALNNFLHGLCMFDGDRKVVVSNARFAGIYSLRPDEIRCGVSLS
HHHHHHHHHHHHEEHHHHHHHHHHHHHEECCCCEEEEECCCEEEEECCCCCHHCCCCCHH
AIQSACRERGTFVESWSERRLGRCSDDISEVSSLQDGRTILVRCQPVAGGGWMTVHEDIT
HHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCEEEHHHHH
ERYRSEQQIAHMARHDLLTGLLNRGAFHERMDEACARLRRWGETFSVIMLDLDRFKLVND
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHEEEEEEHHHHHHHHH
SLGHPAGDALLRAVVSRLKACIRETDVLARLGGDEFAVLQTRTKDSYNEAVAFADRIVNC
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
LIDPIEIDGHQLVISTSAGIALAPQHGTDSDELIKNADLALYRAKAAGRNGYVTFETAMK
HCCCEEECCCEEEEEECCCEEECCCCCCCHHHHHHCCCHHEEEHHCCCCCCCEEEHHHHH
DRANARQQLEGELRQAILNREFDLYYQPQVEARSGRVIGAEALLRWRHPRRGFVPPSEFI
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCEECHHHHHHHCCCCCCCCCCHHCC
PVAEETGLIEKLGEWVLKEAAAEAIRWPAPIKLAINLSPVQLSRGNLTDTVTQALRLSGL
CCHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCCHHHHHHHHHHCCC
PPERLEVEITENVFLEDEVNNLAVIRQLRSLGVSVALDDFGTGYSSLSYLTRFPFDQIKI
CCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCCCCEEH
DKFFSMNLIERSDCATIVSSVITLARGLGISTVAEGVETVRQFELLREAGVDYFQGYLFG
HHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
HPVPASALNFGAAHDITRITEVA
CCCCHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]