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The map label for this gene is ggt [H]

Identifier: 86747209

GI number: 86747209

Start: 84920

End: 86704

Strand: Reverse

Name: ggt [H]

Synonym: RPB_0082

Alternate gene names: 86747209

Gene position: 86704-84920 (Counterclockwise)

Preceding gene: 86747211

Following gene: 86747207

Centisome position: 1.63

GC content: 70.36

Gene sequence:

>1785_bases
ATGCAGGACAGCACAACACTTGCACCGTCGGAAACCCCGCCCCGTACGATGACGATGCTTCATCGCAAAGCCGTGACAGC
GCTGGTTGCAATGGTCGCGCTGGTCGTGGTCCCGGCCACCGCCCCGGCACAGGACATGCGCGGCGGCGCCGCGCGGGCGC
CGGGTGCGGCCTCCGCCGTCGTCGCCCGACACGGCATGGTGGTGGCGCAGGAGCGGCTCTCGGCGGAAGTGGGGGCGCGC
TTTCTCGCGCGCGGCGGCAACGCGATCGATGCCGCGGTCGCGACCGGCTTCGCGATGGCGGTGACCTATCCGCGCGCCGG
CAATCTCGGCGGCGGCGGCTTCATGCTGATCCACGCCGCCGCCAGGAACGAGGACGTCGCGATCGACTATCGCGAGACCG
CGCCGCAGGCCGCCACCCGCGAGATGTTCCTCACCGACGGCAAGCCCGATCCGGACAAGTCCCGCCGATCCGCGCTCGGC
ATCGGCGTCCCCGGCACGGTCGCGGGTCTGGCGCTGGCGCTCGACAAATACGGCTCCGGCAAGTTCTCGCTCGCCGAGGT
GATTGCGCCCGCCATCGCGCTCGCGCGCGACGGCATCAGCGTCGCCGACGACACCGCCGACACGCTGCCGGACTGGCATC
CCTGGCTGTCGCGCTGGCCGTCGACGCGCAAGATCTTCGCCCGGCCCGACGGCTCGCCGCTGCGCGAGGGCGACCGGCTG
GTGCAGCCCGACCTCGCCGCGACGCTGCAGGCGATCGCAGATCACGGCCCCGACGGCTTCTATCGCGGCGGCGTCGCGGA
CAAACTGGCGCGCGGCATTCGGGACGCCGGCGGGATCATCACGACGGATGATCTGGCGAACTATCAGGCCATCGTCCGCG
CGCCCGTCCGCGGCAACTATCGCGGCTACGACATCGTGGCGATGCCGCAGCCGTCGTCGGGCGGCGTGGTGCTGATCGAG
ACGCTGAACATCCTCGAAGGTTTTCCGATGCCGTCGCTAGAGCAGGGCAGCGCGCCGTCGCTGCATCTGCTGATCGAGGC
GATGAAGCGCGCCTATGCGGATCGCGCCCGCTATCTCGGCGATCCGGCCTATGTCGACGCGCCACTGTCGACGCTGCTGT
CGAAGGACTATGCGGCGACACTGCGTGCGGGCATCGACGCCGACCGCGCCACGCCTGCCGTCGTCGCGCCGCCGCAGCCG
AAGGAGGGCGAGAACACCACGCACTATTCCGTCGCCGACGATCAGGGCAACGCCGTCAGCAACACCTATACGCTGAATTT
CTCCTATGGGGTGGGCCTCGTCGCCGACGGCACCGGCGTGCTGCTCAACAACGAGCTCGACGATTTCACCGCGGCGCCCG
GCGCGGCGAACGCCTATGGGCTGGTCGGCTTCGGCGCCAATCTGCCGGCGCCCGGCAAGCGGCCGCTGTCGTCGATGTCG
CCGACCATCGTGCTGAAGGACGGCAAACCGGTGCTGGTCACCGGCTCGCCGGGCGGCAGCCGGATCATCTCGGCGACCCT
GCAGGTGATCGTCAATGTGCTCGACTATCGCATGAACATCGCCGCCGCTGTCGGCGCGCCGCGGCTGCATCATCAATGGC
TGCCGGACGAGCTCCGCGTCGAGCAAGGCTTTCCGGACGCGACGCTGGATGCGTTGCGCGCGATGGGCCACCGCATCGCC
ACGCCGCTCGGCCAGACCTCGGCGAACAGCATCGTCATCGACGCCGACGGCTTCCACGGCGCCCCCGATCCCCGCACCCG
CGGCGCCACGGCGGCCGGCAACTAG

Upstream 100 bases:

>100_bases
CTCTCGCGAGTGGTCCGCCGCGGTCGATGACGTCATCTTGTGTTCCTCGTTCCCGACCGGCGTTTGGCGCGCCGCGCCGA
AACCACTATAGGATTCCGGC

Downstream 100 bases:

>100_bases
AGCAGTTCCGCCGTCATCCTGAGGTGCCCGCCGGGCCGCGCTGTGCGCGGCGCGGCGGGCCTCGAAGGATGGGCCGCTGG
CACCTCGGGCCGCATCCTTC

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MQDSTTLAPSETPPRTMTMLHRKAVTALVAMVALVVVPATAPAQDMRGGAARAPGAASAVVARHGMVVAQERLSAEVGAR
FLARGGNAIDAAVATGFAMAVTYPRAGNLGGGGFMLIHAAARNEDVAIDYRETAPQAATREMFLTDGKPDPDKSRRSALG
IGVPGTVAGLALALDKYGSGKFSLAEVIAPAIALARDGISVADDTADTLPDWHPWLSRWPSTRKIFARPDGSPLREGDRL
VQPDLAATLQAIADHGPDGFYRGGVADKLARGIRDAGGIITTDDLANYQAIVRAPVRGNYRGYDIVAMPQPSSGGVVLIE
TLNILEGFPMPSLEQGSAPSLHLLIEAMKRAYADRARYLGDPAYVDAPLSTLLSKDYAATLRAGIDADRATPAVVAPPQP
KEGENTTHYSVADDQGNAVSNTYTLNFSYGVGLVADGTGVLLNNELDDFTAAPGAANAYGLVGFGANLPAPGKRPLSSMS
PTIVLKDGKPVLVTGSPGGSRIISATLQVIVNVLDYRMNIAAAVGAPRLHHQWLPDELRVEQGFPDATLDALRAMGHRIA
TPLGQTSANSIVIDADGFHGAPDPRTRGATAAGN

Sequences:

>Translated_594_residues
MQDSTTLAPSETPPRTMTMLHRKAVTALVAMVALVVVPATAPAQDMRGGAARAPGAASAVVARHGMVVAQERLSAEVGAR
FLARGGNAIDAAVATGFAMAVTYPRAGNLGGGGFMLIHAAARNEDVAIDYRETAPQAATREMFLTDGKPDPDKSRRSALG
IGVPGTVAGLALALDKYGSGKFSLAEVIAPAIALARDGISVADDTADTLPDWHPWLSRWPSTRKIFARPDGSPLREGDRL
VQPDLAATLQAIADHGPDGFYRGGVADKLARGIRDAGGIITTDDLANYQAIVRAPVRGNYRGYDIVAMPQPSSGGVVLIE
TLNILEGFPMPSLEQGSAPSLHLLIEAMKRAYADRARYLGDPAYVDAPLSTLLSKDYAATLRAGIDADRATPAVVAPPQP
KEGENTTHYSVADDQGNAVSNTYTLNFSYGVGLVADGTGVLLNNELDDFTAAPGAANAYGLVGFGANLPAPGKRPLSSMS
PTIVLKDGKPVLVTGSPGGSRIISATLQVIVNVLDYRMNIAAAVGAPRLHHQWLPDELRVEQGFPDATLDALRAMGHRIA
TPLGQTSANSIVIDADGFHGAPDPRTRGATAAGN
>Mature_594_residues
MQDSTTLAPSETPPRTMTMLHRKAVTALVAMVALVVVPATAPAQDMRGGAARAPGAASAVVARHGMVVAQERLSAEVGAR
FLARGGNAIDAAVATGFAMAVTYPRAGNLGGGGFMLIHAAARNEDVAIDYRETAPQAATREMFLTDGKPDPDKSRRSALG
IGVPGTVAGLALALDKYGSGKFSLAEVIAPAIALARDGISVADDTADTLPDWHPWLSRWPSTRKIFARPDGSPLREGDRL
VQPDLAATLQAIADHGPDGFYRGGVADKLARGIRDAGGIITTDDLANYQAIVRAPVRGNYRGYDIVAMPQPSSGGVVLIE
TLNILEGFPMPSLEQGSAPSLHLLIEAMKRAYADRARYLGDPAYVDAPLSTLLSKDYAATLRAGIDADRATPAVVAPPQP
KEGENTTHYSVADDQGNAVSNTYTLNFSYGVGLVADGTGVLLNNELDDFTAAPGAANAYGLVGFGANLPAPGKRPLSSMS
PTIVLKDGKPVLVTGSPGGSRIISATLQVIVNVLDYRMNIAAAVGAPRLHHQWLPDELRVEQGFPDATLDALRAMGHRIA
TPLGQTSANSIVIDADGFHGAPDPRTRGATAAGN

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=539, Percent_Identity=34.6938775510204, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI73915090, Length=539, Percent_Identity=34.6938775510204, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI73915096, Length=539, Percent_Identity=34.6938775510204, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI73915094, Length=539, Percent_Identity=34.6938775510204, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI113429324, Length=534, Percent_Identity=32.9588014981273, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI113429326, Length=542, Percent_Identity=32.8413284132841, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI109148539, Length=519, Percent_Identity=34.8747591522158, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI153266885, Length=483, Percent_Identity=30.8488612836439, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI153266901, Length=484, Percent_Identity=30.9917355371901, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI153266907, Length=483, Percent_Identity=30.0207039337474, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI30581157, Length=225, Percent_Identity=36.4444444444444, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI30581155, Length=225, Percent_Identity=36.4444444444444, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI218505805, Length=227, Percent_Identity=34.8017621145374, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI310124095, Length=227, Percent_Identity=32.5991189427313, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1789856, Length=540, Percent_Identity=51.8518518518518, Blast_Score=535, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI72000294, Length=495, Percent_Identity=34.7474747474747, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI212646519, Length=495, Percent_Identity=34.7474747474747, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17506189, Length=585, Percent_Identity=32.8205128205128, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI193208247, Length=573, Percent_Identity=32.9842931937173, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI193208245, Length=573, Percent_Identity=32.9842931937173, Blast_Score=238, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17542894, Length=549, Percent_Identity=32.2404371584699, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI17564448, Length=417, Percent_Identity=25.4196642685851, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72001497, Length=254, Percent_Identity=25.9842519685039, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI72001495, Length=254, Percent_Identity=25.9842519685039, Blast_Score=90, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323330, Length=545, Percent_Identity=29.9082568807339, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI161077878, Length=549, Percent_Identity=32.2404371584699, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI161077880, Length=549, Percent_Identity=32.2404371584699, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI45551474, Length=549, Percent_Identity=32.2404371584699, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24642670, Length=549, Percent_Identity=32.2404371584699, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24642666, Length=549, Percent_Identity=32.2404371584699, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI161077496, Length=496, Percent_Identity=34.4758064516129, Blast_Score=228, Evalue=8e-60,
Organism=Drosophila melanogaster, GI18859893, Length=531, Percent_Identity=32.7683615819209, Blast_Score=216, Evalue=5e-56,
Organism=Drosophila melanogaster, GI18859741, Length=510, Percent_Identity=31.1764705882353, Blast_Score=204, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 61859; Mature: 61859

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDSTTLAPSETPPRTMTMLHRKAVTALVAMVALVVVPATAPAQDMRGGAARAPGAASAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHH
VARHGMVVAQERLSAEVGARFLARGGNAIDAAVATGFAMAVTYPRAGNLGGGGFMLIHAA
HHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEEEECCCCCCCCCCCEEEEEEE
ARNEDVAIDYRETAPQAATREMFLTDGKPDPDKSRRSALGIGVPGTVAGLALALDKYGSG
CCCCCEEEEEHHCCCCHHHHHEEEECCCCCCCHHHHCEECCCCCHHHHHHHHHHHHCCCC
KFSLAEVIAPAIALARDGISVADDTADTLPDWHPWLSRWPSTRKIFARPDGSPLREGDRL
CCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCC
VQPDLAATLQAIADHGPDGFYRGGVADKLARGIRDAGGIITTDDLANYQAIVRAPVRGNY
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECHHHCCEEEEECCCCCCC
RGYDIVAMPQPSSGGVVLIETLNILEGFPMPSLEQGSAPSLHLLIEAMKRAYADRARYLG
CCEEEEEECCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DPAYVDAPLSTLLSKDYAATLRAGIDADRATPAVVAPPQPKEGENTTHYSVADDQGNAVS
CCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCEEC
NTYTLNFSYGVGLVADGTGVLLNNELDDFTAAPGAANAYGLVGFGANLPAPGKRPLSSMS
EEEEEEEECCCEEEECCCEEEECCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
PTIVLKDGKPVLVTGSPGGSRIISATLQVIVNVLDYRMNIAAAVGAPRLHHQWLPDELRV
CEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHH
EQGFPDATLDALRAMGHRIATPLGQTSANSIVIDADGFHGAPDPRTRGATAAGN
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQDSTTLAPSETPPRTMTMLHRKAVTALVAMVALVVVPATAPAQDMRGGAARAPGAASAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHH
VARHGMVVAQERLSAEVGARFLARGGNAIDAAVATGFAMAVTYPRAGNLGGGGFMLIHAA
HHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCEEEEEECCCCCCCCCCCEEEEEEE
ARNEDVAIDYRETAPQAATREMFLTDGKPDPDKSRRSALGIGVPGTVAGLALALDKYGSG
CCCCCEEEEEHHCCCCHHHHHEEEECCCCCCCHHHHCEECCCCCHHHHHHHHHHHHCCCC
KFSLAEVIAPAIALARDGISVADDTADTLPDWHPWLSRWPSTRKIFARPDGSPLREGDRL
CCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCHHHHHCCCCCEEEECCCCCCCCCCCCC
VQPDLAATLQAIADHGPDGFYRGGVADKLARGIRDAGGIITTDDLANYQAIVRAPVRGNY
CCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEECHHHCCEEEEECCCCCCC
RGYDIVAMPQPSSGGVVLIETLNILEGFPMPSLEQGSAPSLHLLIEAMKRAYADRARYLG
CCEEEEEECCCCCCCEEEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
DPAYVDAPLSTLLSKDYAATLRAGIDADRATPAVVAPPQPKEGENTTHYSVADDQGNAVS
CCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCEEC
NTYTLNFSYGVGLVADGTGVLLNNELDDFTAAPGAANAYGLVGFGANLPAPGKRPLSSMS
EEEEEEEECCCEEEECCCEEEECCCCCHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
PTIVLKDGKPVLVTGSPGGSRIISATLQVIVNVLDYRMNIAAAVGAPRLHHQWLPDELRV
CEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHH
EQGFPDATLDALRAMGHRIATPLGQTSANSIVIDADGFHGAPDPRTRGATAAGN
HCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]