Click here to switch to the map view.

The map label for this gene is engA

Identifier: 86608739

GI number: 86608739

Start: 1320403

End: 1321782

Strand: Direct

Name: engA

Synonym: CYB_1263

Alternate gene names: 86608739

Gene position: 1320403-1321782 (Clockwise)

Preceding gene: 86608737

Following gene: 86608740

Centisome position: 43.34

GC content: 61.09

Gene sequence:

>1380_bases
GTGCCCCTACCTCTTGTGGCCATTGTGGGCCGCCCCAACGTGGGCAAATCCACCCTCGTCAACCGCATGGCGGGGGTGCG
TTCGGCCATTGTGCACGATGAGCCCGGCGTGACCCGGGATCGTCTGTACCAGGAGGTGGAGTGGAACGGGCGCCGCTTGC
GGGTGGTGGATACCGGCGGCCTGGTTTTTGGGGATGACAGCGAATTTTTACCCCACATTCGCCAGCAAGCAATGGCAGCC
ATGGCCGAGGCGCAGGCCGTGATCTTCGTGGTGGATGGCCGAGAGGGACTGACACCCGCCGATGTAGAAGTGGCCGATTG
GCTGCGCAAACAACCCCTGCCGGTGGTGGTGGCCGTAAACAAGTGCGAGTCGGGGCAGATGGGCCTGGCTCAGGCAGCAG
CCTTTTGGGAGCTGGGGCTGGGGGATCCGATCCCCTGTTCCGGCATTCATGGCAATGGGGTAGCCGAGCTGTTGGAGGCG
GTGCTGGCTCACTTGCCCGAAGTGACCGCAGAAGCCGCAGGCGAGCCAGATCCCATCGCCGTCTCGATTGTGGGACGGCC
CAACGTCGGCAAATCCAGCTTGCTCAACCGCCTGGTAGGATCCGAGCGGGCCATCGTCAGCCCCATTTCCGGCACCACCC
GCGATGCCATCGACACCGTGGTCACCTGGGAAGGGCAGCCCTATCGCCTCATCGATACCGCCGGCATCCGCAAAAAAAAC
CGCGTGCAGTACGGCATTGAGTTCTTCAGCATCAACCGGGCCTTCAAGGCCATCCAGCGCTCGGATGCAGTGCTGCTGGT
GATCGATGCTTTGGAGGGGGTTACCGAACAGGACCAGAGGCTGGCCGGGCGCATCGAAGAAGAGGGCCGCGCCTGCGTTG
TCGTCGTCAACAAGTGGGATGCAGTAGAAAACAAAGATACCCACACCATCAACGAGTTCACCCGCGAGATTCGCGACAGG
CTTTACTTTATTGAATGGGCGCCGCTCCTGTTTGTCAGCGCCCTCACTGGGCAACGCACCCACAAAATCTTTGAGCAGGT
GAATACCGTGGTGGCCGCCCACCGCAAACGGGTTCCCACCGCTGTGGTCAACGAAGTGCTCCAGGATGCTCTTGCCTGGC
AATCGCCCCCCACCAACCGCCAGGGCAAGCAGGGCAGAATTTACTACGGCACCCAGGTGGCGGATCGGCCCCCCACCTTT
GTTCTGTTTGTCAACGATCCCGATTTGTTTAAGGATAACTACCGCCGCTTCCTGGAAAAGCACTTCCGGCAAAACCTGGA
CTTTACCGGTACCCCCATTCGCTTTCTCTGGCGCGGCAAATCCGAGCGCTTGGTTGGGCGGGCGGTGCGAAAATTGGAGA
GATCCCTGACCTCTCGTTAG

Upstream 100 bases:

>100_bases
CCTGCATCCAAAGCAATGATCGAGATTGGCGGCTTTGGGCATCCGGGATCCGGAACGGCTAGGATAGATATCCCATCTCA
AGTTATCGACGAGCCGAACA

Downstream 100 bases:

>100_bases
GCCCTCTGGTCTACTGAAAGCCTATGGCTGTGGATCCCAACGTCAAAACCCTGGTTGACAACCGTCGCGCCCGCTTCGAG
TACGACATCTTGGAGACCTA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MPLPLVAIVGRPNVGKSTLVNRMAGVRSAIVHDEPGVTRDRLYQEVEWNGRRLRVVDTGGLVFGDDSEFLPHIRQQAMAA
MAEAQAVIFVVDGREGLTPADVEVADWLRKQPLPVVVAVNKCESGQMGLAQAAAFWELGLGDPIPCSGIHGNGVAELLEA
VLAHLPEVTAEAAGEPDPIAVSIVGRPNVGKSSLLNRLVGSERAIVSPISGTTRDAIDTVVTWEGQPYRLIDTAGIRKKN
RVQYGIEFFSINRAFKAIQRSDAVLLVIDALEGVTEQDQRLAGRIEEEGRACVVVVNKWDAVENKDTHTINEFTREIRDR
LYFIEWAPLLFVSALTGQRTHKIFEQVNTVVAAHRKRVPTAVVNEVLQDALAWQSPPTNRQGKQGRIYYGTQVADRPPTF
VLFVNDPDLFKDNYRRFLEKHFRQNLDFTGTPIRFLWRGKSERLVGRAVRKLERSLTSR

Sequences:

>Translated_459_residues
MPLPLVAIVGRPNVGKSTLVNRMAGVRSAIVHDEPGVTRDRLYQEVEWNGRRLRVVDTGGLVFGDDSEFLPHIRQQAMAA
MAEAQAVIFVVDGREGLTPADVEVADWLRKQPLPVVVAVNKCESGQMGLAQAAAFWELGLGDPIPCSGIHGNGVAELLEA
VLAHLPEVTAEAAGEPDPIAVSIVGRPNVGKSSLLNRLVGSERAIVSPISGTTRDAIDTVVTWEGQPYRLIDTAGIRKKN
RVQYGIEFFSINRAFKAIQRSDAVLLVIDALEGVTEQDQRLAGRIEEEGRACVVVVNKWDAVENKDTHTINEFTREIRDR
LYFIEWAPLLFVSALTGQRTHKIFEQVNTVVAAHRKRVPTAVVNEVLQDALAWQSPPTNRQGKQGRIYYGTQVADRPPTF
VLFVNDPDLFKDNYRRFLEKHFRQNLDFTGTPIRFLWRGKSERLVGRAVRKLERSLTSR
>Mature_458_residues
PLPLVAIVGRPNVGKSTLVNRMAGVRSAIVHDEPGVTRDRLYQEVEWNGRRLRVVDTGGLVFGDDSEFLPHIRQQAMAAM
AEAQAVIFVVDGREGLTPADVEVADWLRKQPLPVVVAVNKCESGQMGLAQAAAFWELGLGDPIPCSGIHGNGVAELLEAV
LAHLPEVTAEAAGEPDPIAVSIVGRPNVGKSSLLNRLVGSERAIVSPISGTTRDAIDTVVTWEGQPYRLIDTAGIRKKNR
VQYGIEFFSINRAFKAIQRSDAVLLVIDALEGVTEQDQRLAGRIEEEGRACVVVVNKWDAVENKDTHTINEFTREIRDRL
YFIEWAPLLFVSALTGQRTHKIFEQVNTVVAAHRKRVPTAVVNEVLQDALAWQSPPTNRQGKQGRIYYGTQVADRPPTFV
LFVNDPDLFKDNYRRFLEKHFRQNLDFTGTPIRFLWRGKSERLVGRAVRKLERSLTSR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=465, Percent_Identity=38.7096774193548, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI2367268, Length=115, Percent_Identity=43.4782608695652, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788919, Length=169, Percent_Identity=33.7278106508876, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17507259, Length=90, Percent_Identity=48.8888888888889, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=206, Percent_Identity=29.126213592233, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_SYNJB (Q2JM09)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477501.1
- ProteinModelPortal:   Q2JM09
- SMR:   Q2JM09
- STRING:   Q2JM09
- GeneID:   3900997
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1263
- TIGR:   CYB_1263
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- PhylomeDB:   Q2JM09
- ProtClustDB:   PRK00093
- BioCyc:   SSP321332:CYB_1263-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 51060; Mature: 50929

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPLVAIVGRPNVGKSTLVNRMAGVRSAIVHDEPGVTRDRLYQEVEWNGRRLRVVDTGG
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEECCC
LVFGDDSEFLPHIRQQAMAAMAEAQAVIFVVDGREGLTPADVEVADWLRKQPLPVVVAVN
EEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEE
KCESGQMGLAQAAAFWELGLGDPIPCSGIHGNGVAELLEAVLAHLPEVTAEAAGEPDPIA
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCEE
VSIVGRPNVGKSSLLNRLVGSERAIVSPISGTTRDAIDTVVTWEGQPYRLIDTAGIRKKN
EEEECCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHEEEEECCCCEEEEECCCCCCCC
RVQYGIEFFSINRAFKAIQRSDAVLLVIDALEGVTEQDQRLAGRIEEEGRACVVVVNKWD
CCEECCEEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCC
AVENKDTHTINEFTREIRDRLYFIEWAPLLFVSALTGQRTHKIFEQVNTVVAAHRKRVPT
CCCCCCCHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
AVVNEVLQDALAWQSPPTNRQGKQGRIYYGTQVADRPPTFVLFVNDPDLFKDNYRRFLEK
HHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCCHHHHHHHHHHHHH
HFRQNLDFTGTPIRFLWRGKSERLVGRAVRKLERSLTSR
HHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLPLVAIVGRPNVGKSTLVNRMAGVRSAIVHDEPGVTRDRLYQEVEWNGRRLRVVDTGG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEEEECCC
LVFGDDSEFLPHIRQQAMAAMAEAQAVIFVVDGREGLTPADVEVADWLRKQPLPVVVAVN
EEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEE
KCESGQMGLAQAAAFWELGLGDPIPCSGIHGNGVAELLEAVLAHLPEVTAEAAGEPDPIA
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCEE
VSIVGRPNVGKSSLLNRLVGSERAIVSPISGTTRDAIDTVVTWEGQPYRLIDTAGIRKKN
EEEECCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHEEEEECCCCEEEEECCCCCCCC
RVQYGIEFFSINRAFKAIQRSDAVLLVIDALEGVTEQDQRLAGRIEEEGRACVVVVNKWD
CCEECCEEEHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCC
AVENKDTHTINEFTREIRDRLYFIEWAPLLFVSALTGQRTHKIFEQVNTVVAAHRKRVPT
CCCCCCCHHHHHHHHHHHHHEEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCH
AVVNEVLQDALAWQSPPTNRQGKQGRIYYGTQVADRPPTFVLFVNDPDLFKDNYRRFLEK
HHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEECCCCCEEEEEECCCHHHHHHHHHHHHH
HFRQNLDFTGTPIRFLWRGKSERLVGRAVRKLERSLTSR
HHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA