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The map label for this gene is phoE [H]

Identifier: 86608499

GI number: 86608499

Start: 1058903

End: 1060246

Strand: Direct

Name: phoE [H]

Synonym: CYB_1020

Alternate gene names: 86608499

Gene position: 1058903-1060246 (Clockwise)

Preceding gene: 86608492

Following gene: 86608500

Centisome position: 34.76

GC content: 60.19

Gene sequence:

>1344_bases
TTGATCGTGCGCCATGGTGAGAGCACCTTCAACCTGGAAAATCGCATTCAAGGCCGCTCCGATCTCTCCCGGCTCACCCC
CACTGGAGAAGTGCAGGCGCAGCGTGTAGCCGAGGCCCTGGCCGGGATCCCGTTGGATTGCGCCTATTGCAGCCCCCTGT
CTCGCGCCCTCGATACCGCTCGCGTCATTTTGAAAGACCGAGAAGGGATCCCTCTGCACGTTACCGATCAACTGCGGGAG
ATCGACCTGACGGCCTGGGAAGGGCTGACCTTTGCTGAGGTGAAGGAGAAATACCCCGAGGATTACCATCTGTGGCGGCA
CCATCCCGACAACCTGGAGCTGGAGGGCCGCTTTCCGGTGCGGGATCTCTGGCAGCAGGCGCAGGGGTTTTGGGAAATGC
TGGCTTTCCATCTGCAATCGGCTTCGGGCCCCTGGAACCATGGAGCGGATCCCTCCCCAAGGCAGCCCCTCAATATCCTC
ATCGTGGGCCACAGCGGCATCAATCGCGCCCTGGTCAGCACCGCCATCGGCCTGGGGCCACACCACTATCACCGCCTTGG
GCAGGATAACTGCGCCATCAGCGTTCTCAATTTTCCCGAGGGCCTGCAGGGGCCGCCACAACTGGAATCTCTGAACATCA
CCGCTCACCTCGGCCAAGCCCTGCCCAAGCGCAAGCAGGGGATGCGCATCTTGCTGGTGCGGCATGGGGAAACCCAATGG
AACCGAGAGCGCCGTTTTCAAGGGCAGCGGGATATCCCCCTCAATGCCACCGGGGAGGAACAGGCAGCCAAGGTGGCAGA
ATTTTTGGCCACTCAACCTCTGCAACTGGCCTTCTCCAGCCCCCTGAAGCGCCCTTGGGCCACAGCCGATGCCATCTGCA
GCAACCACAGCAACCTCATTTTGCGCCCAATGCCCGACTTGCAAGAGATCTGCCACGGCGACTGGGAGGGCAAGCTGCAA
AGCGAAGTCGAAGCCGAATACCCCGGCGAGCTGGAGCGCTGGCAACGGGATCCCGCCAGTGTGCAAATGCCCAATGGGGA
AAACCTTCACCAGGTGTGGGAGCGCACTCGCTTGGCCTGGCAGGAGCTTTTGGCCATCACTGCAGCCCAGTTTCCTCAGG
GCACGGCGGTTGTTGTTGCCCACGATGCCATCAACAAAGCAATCCTCTGTCAGTTATTCAACCTTTCCCCACAGGCTTTT
TGGATCTTCAAGCAGGGGAATGGTGCCATTACGGTGATCGACTATCCAGAAGGCAAGGAGGGTGCCCCGGTTTTGAAGGT
GTTGAACCTCACCACCCATCTGTCGGGCCAGATCTTGGACTGCACCACCGCTGGAGCTTTGTAA

Upstream 100 bases:

>100_bases
GGTGTTCTAAGGACTCCGTCCCGCTACTGCGATGAGTAAGTCCATGCAAGCGATGGCAAGGACTCCGTCCCGCTACCGCG
ACCAGCCTGCCCTGCGCATC

Downstream 100 bases:

>100_bases
AGATGGGCTCATCCCCTCTCCGCGAGCTAACAGGACGACTAACAGGACAAAATGTGCATCTCCAGGGAGTGCGCCTGTTG
GATCCTTGGCGTCAGCGGGA

Product: phosphoglycerate mutase family protein

Products: 3-phospho-D-glycerate

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MIVRHGESTFNLENRIQGRSDLSRLTPTGEVQAQRVAEALAGIPLDCAYCSPLSRALDTARVILKDREGIPLHVTDQLRE
IDLTAWEGLTFAEVKEKYPEDYHLWRHHPDNLELEGRFPVRDLWQQAQGFWEMLAFHLQSASGPWNHGADPSPRQPLNIL
IVGHSGINRALVSTAIGLGPHHYHRLGQDNCAISVLNFPEGLQGPPQLESLNITAHLGQALPKRKQGMRILLVRHGETQW
NRERRFQGQRDIPLNATGEEQAAKVAEFLATQPLQLAFSSPLKRPWATADAICSNHSNLILRPMPDLQEICHGDWEGKLQ
SEVEAEYPGELERWQRDPASVQMPNGENLHQVWERTRLAWQELLAITAAQFPQGTAVVVAHDAINKAILCQLFNLSPQAF
WIFKQGNGAITVIDYPEGKEGAPVLKVLNLTTHLSGQILDCTTAGAL

Sequences:

>Translated_447_residues
MIVRHGESTFNLENRIQGRSDLSRLTPTGEVQAQRVAEALAGIPLDCAYCSPLSRALDTARVILKDREGIPLHVTDQLRE
IDLTAWEGLTFAEVKEKYPEDYHLWRHHPDNLELEGRFPVRDLWQQAQGFWEMLAFHLQSASGPWNHGADPSPRQPLNIL
IVGHSGINRALVSTAIGLGPHHYHRLGQDNCAISVLNFPEGLQGPPQLESLNITAHLGQALPKRKQGMRILLVRHGETQW
NRERRFQGQRDIPLNATGEEQAAKVAEFLATQPLQLAFSSPLKRPWATADAICSNHSNLILRPMPDLQEICHGDWEGKLQ
SEVEAEYPGELERWQRDPASVQMPNGENLHQVWERTRLAWQELLAITAAQFPQGTAVVVAHDAINKAILCQLFNLSPQAF
WIFKQGNGAITVIDYPEGKEGAPVLKVLNLTTHLSGQILDCTTAGAL
>Mature_447_residues
MIVRHGESTFNLENRIQGRSDLSRLTPTGEVQAQRVAEALAGIPLDCAYCSPLSRALDTARVILKDREGIPLHVTDQLRE
IDLTAWEGLTFAEVKEKYPEDYHLWRHHPDNLELEGRFPVRDLWQQAQGFWEMLAFHLQSASGPWNHGADPSPRQPLNIL
IVGHSGINRALVSTAIGLGPHHYHRLGQDNCAISVLNFPEGLQGPPQLESLNITAHLGQALPKRKQGMRILLVRHGETQW
NRERRFQGQRDIPLNATGEEQAAKVAEFLATQPLQLAFSSPLKRPWATADAICSNHSNLILRPMPDLQEICHGDWEGKLQ
SEVEAEYPGELERWQRDPASVQMPNGENLHQVWERTRLAWQELLAITAAQFPQGTAVVVAHDAINKAILCQLFNLSPQAF
WIFKQGNGAITVIDYPEGKEGAPVLKVLNLTTHLSGQILDCTTAGAL

Specific function: Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activtiy [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=202, Percent_Identity=28.2178217821782, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790856, Length=196, Percent_Identity=31.1224489795918, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786970, Length=188, Percent_Identity=30.8510638297872, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 5.4.2.1

Molecular weight: Translated: 49947; Mature: 49947

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRHGESTFNLENRIQGRSDLSRLTPTGEVQAQRVAEALAGIPLDCAYCSPLSRALDTA
CEEECCCCCCCHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHH
RVILKDREGIPLHVTDQLREIDLTAWEGLTFAEVKEKYPEDYHLWRHHPDNLELEGRFPV
HHHHCCCCCCCEEECCHHHHCCCHHCCCCCHHHHHHHCCCCCHHHCCCCCCEEEECCCCH
RDLWQQAQGFWEMLAFHLQSASGPWNHGADPSPRQPLNILIVGHSGINRALVSTAIGLGP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCC
HHYHRLGQDNCAISVLNFPEGLQGPPQLESLNITAHLGQALPKRKQGMRILLVRHGETQW
HHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHCCHHHCCCEEEEEECCCCHH
NRERRFQGQRDIPLNATGEEQAAKVAEFLATQPLQLAFSSPLKRPWATADAICSNHSNLI
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHCCCCCEE
LRPMPDLQEICHGDWEGKLQSEVEAEYPGELERWQRDPASVQMPNGENLHQVWERTRLAW
EECCCHHHHHHCCCCCCCHHHCCCCCCCCHHHHHCCCCCCEECCCCCCHHHHHHHHHHHH
QELLAITAAQFPQGTAVVVAHDAINKAILCQLFNLSPQAFWIFKQGNGAITVIDYPEGKE
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCCCC
GAPVLKVLNLTTHLSGQILDCTTAGAL
CCCHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MIVRHGESTFNLENRIQGRSDLSRLTPTGEVQAQRVAEALAGIPLDCAYCSPLSRALDTA
CEEECCCCCCCHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHCHHHHHHHHH
RVILKDREGIPLHVTDQLREIDLTAWEGLTFAEVKEKYPEDYHLWRHHPDNLELEGRFPV
HHHHCCCCCCCEEECCHHHHCCCHHCCCCCHHHHHHHCCCCCHHHCCCCCCEEEECCCCH
RDLWQQAQGFWEMLAFHLQSASGPWNHGADPSPRQPLNILIVGHSGINRALVSTAIGLGP
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCC
HHYHRLGQDNCAISVLNFPEGLQGPPQLESLNITAHLGQALPKRKQGMRILLVRHGETQW
HHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHCCHHHCCCEEEEEECCCCHH
NRERRFQGQRDIPLNATGEEQAAKVAEFLATQPLQLAFSSPLKRPWATADAICSNHSNLI
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHCCCCCEE
LRPMPDLQEICHGDWEGKLQSEVEAEYPGELERWQRDPASVQMPNGENLHQVWERTRLAW
EECCCHHHHHHCCCCCCCHHHCCCCCCCCHHHHHCCCCCCEECCCCCCHHHHHHHHHHHH
QELLAITAAQFPQGTAVVVAHDAINKAILCQLFNLSPQAFWIFKQGNGAITVIDYPEGKE
HHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEECCCCCC
GAPVLKVLNLTTHLSGQILDCTTAGAL
CCCHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phospho-D-glycerate

Specific reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]