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The map label for this gene is glk [H]

Identifier: 86608453

GI number: 86608453

Start: 1009689

End: 1010732

Strand: Direct

Name: glk [H]

Synonym: CYB_0974

Alternate gene names: 86608453

Gene position: 1009689-1010732 (Clockwise)

Preceding gene: 86608451

Following gene: 86608454

Centisome position: 33.14

GC content: 60.54

Gene sequence:

>1044_bases
ATGGACTTGTTGTTGGCAGGAGACATCGGGGGCACCAAAACCAGCCTCAGCCTTGTCAATGCCGAGGATCCCGAGCACAG
CCTTTACCACTGCCGCTATGCCAGCCAAGATTACGCCAACCTCGCCCCAATGGTGGGAGAGTTTCTGGCCCAGGCTCGGC
GGGAGCTGGGGCGAGATCCACAGCCTGCTGCCGCCTGTTTTGCAGTGGCCGGCCCCGTCATGGAAACAAGGGGCTCAGGG
TCTGAGGGACAGACTGCCAAAGTGACCAACTTGCCCTGGGATCTGCAGTCGAGCCAATTGGCCGCAGAGCTGGGGATCCC
GCGCGTAGCCTTGATCAACGACTTCAGCGCCGTAGGGTATGGCGTGCTTGCCCTCGGCGACCAGGATCTGGACACCTTGC
AAGTGGGTGAGCGTCAACCGCGGGCTCCGATTGGCGTGATGGGAGCAGGCACGGGTTTGGGGCAGGCTTACCTTACCTGG
GGAGAAGGGGGTTACCAAGTTCATGCCAGCGAGGGCGGTCACGTGGACTTTTCCCCGCGCACCCCTCTGGAGTGGGAGCT
CTTGAGGTATTTGCAAAAACGGCACGGACGTGTCTCCACCGAGCGGGTGGTCTCGGGGCAGGGGATCGTTGCCATTTATC
AATTTTTGCGGGATAGCCAGTGGGGCTCAGGAGAAGAACAGCTGCTGGCCCAAATTGAGGCTTGGGAAAAGGGAGCTAAG
CATATTGACCCGGCAGCCCAAATTGCCAATGCTGCCATGGAAGCACGGGATCCCCTGGCGGTGGAGTGTCTGCGGCTTTT
CATCAGCCTGTACGGGGCTGCAGTCGGGAACTTTGCCCTACACCTATTGCCGCGCGGGGGCCTGTTCATCGCTGGGGGGA
TCGCGCCCAAGCTCTTGCGCCTACTGCATCAAGGGGAGTTTTTGTCCTCGTTTTTGGATAAGGGGCGGATGCGTCCTCTT
CTAGAGCAACTGTCGGTGCAGGTGGTGGTGAATGCGCAGGTGGGGCTGAGGGGAGCTGCTCGCTACGCCGCCAACCTTTT
GTGA

Upstream 100 bases:

>100_bases
TCCCTCTTCTCCCCAGCAGGAGCGGGGAAGCCTTGGGGGCCTGGCATTCTCTCTCCAGAGATGTCAGGGTGGGAAGGAGG
TGCTGGCCGGAGGAAACTGT

Downstream 100 bases:

>100_bases
AGGAGCAGCCGCTGCTGTTGAGGTTGCCACCCCTGGAACACCCCATCCAGCAGGTGATGGCAGCGACCCCAACGGATGCT
GGAATCGTGCTGGAAAATCT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MDLLLAGDIGGTKTSLSLVNAEDPEHSLYHCRYASQDYANLAPMVGEFLAQARRELGRDPQPAAACFAVAGPVMETRGSG
SEGQTAKVTNLPWDLQSSQLAAELGIPRVALINDFSAVGYGVLALGDQDLDTLQVGERQPRAPIGVMGAGTGLGQAYLTW
GEGGYQVHASEGGHVDFSPRTPLEWELLRYLQKRHGRVSTERVVSGQGIVAIYQFLRDSQWGSGEEQLLAQIEAWEKGAK
HIDPAAQIANAAMEARDPLAVECLRLFISLYGAAVGNFALHLLPRGGLFIAGGIAPKLLRLLHQGEFLSSFLDKGRMRPL
LEQLSVQVVVNAQVGLRGAARYAANLL

Sequences:

>Translated_347_residues
MDLLLAGDIGGTKTSLSLVNAEDPEHSLYHCRYASQDYANLAPMVGEFLAQARRELGRDPQPAAACFAVAGPVMETRGSG
SEGQTAKVTNLPWDLQSSQLAAELGIPRVALINDFSAVGYGVLALGDQDLDTLQVGERQPRAPIGVMGAGTGLGQAYLTW
GEGGYQVHASEGGHVDFSPRTPLEWELLRYLQKRHGRVSTERVVSGQGIVAIYQFLRDSQWGSGEEQLLAQIEAWEKGAK
HIDPAAQIANAAMEARDPLAVECLRLFISLYGAAVGNFALHLLPRGGLFIAGGIAPKLLRLLHQGEFLSSFLDKGRMRPL
LEQLSVQVVVNAQVGLRGAARYAANLL
>Mature_347_residues
MDLLLAGDIGGTKTSLSLVNAEDPEHSLYHCRYASQDYANLAPMVGEFLAQARRELGRDPQPAAACFAVAGPVMETRGSG
SEGQTAKVTNLPWDLQSSQLAAELGIPRVALINDFSAVGYGVLALGDQDLDTLQVGERQPRAPIGVMGAGTGLGQAYLTW
GEGGYQVHASEGGHVDFSPRTPLEWELLRYLQKRHGRVSTERVVSGQGIVAIYQFLRDSQWGSGEEQLLAQIEAWEKGAK
HIDPAAQIANAAMEARDPLAVECLRLFISLYGAAVGNFALHLLPRGGLFIAGGIAPKLLRLLHQGEFLSSFLDKGRMRPL
LEQLSVQVVVNAQVGLRGAARYAANLL

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=340, Percent_Identity=31.4705882352941, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 37264; Mature: 37264

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLAGDIGGTKTSLSLVNAEDPEHSLYHCRYASQDYANLAPMVGEFLAQARRELGRDP
CCEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
QPAAACFAVAGPVMETRGSGSEGQTAKVTNLPWDLQSSQLAAELGIPRVALINDFSAVGY
CHHHHHHHHHCCHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEECCCHHHHCE
GVLALGDQDLDTLQVGERQPRAPIGVMGAGTGLGQAYLTWGEGGYQVHASEGGHVDFSPR
EEEEECCCCCHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEECCCCCEEECCCC
TPLEWELLRYLQKRHGRVSTERVVSGQGIVAIYQFLRDSQWGSGEEQLLAQIEAWEKGAK
CCCHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
HIDPAAQIANAAMEARDPLAVECLRLFISLYGAAVGNFALHLLPRGGLFIAGGIAPKLLR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCHHHHHHH
LLHQGEFLSSFLDKGRMRPLLEQLSVQVVVNAQVGLRGAARYAANLL
HHHCCHHHHHHHHCCCCHHHHHHCCEEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MDLLLAGDIGGTKTSLSLVNAEDPEHSLYHCRYASQDYANLAPMVGEFLAQARRELGRDP
CCEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCC
QPAAACFAVAGPVMETRGSGSEGQTAKVTNLPWDLQSSQLAAELGIPRVALINDFSAVGY
CHHHHHHHHHCCHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCEEEECCCHHHHCE
GVLALGDQDLDTLQVGERQPRAPIGVMGAGTGLGQAYLTWGEGGYQVHASEGGHVDFSPR
EEEEECCCCCHHHHCCCCCCCCCEEEEECCCCCCCEEEEECCCCEEEECCCCCEEECCCC
TPLEWELLRYLQKRHGRVSTERVVSGQGIVAIYQFLRDSQWGSGEEQLLAQIEAWEKGAK
CCCHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
HIDPAAQIANAAMEARDPLAVECLRLFISLYGAAVGNFALHLLPRGGLFIAGGIAPKLLR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCHHHHHHH
LLHQGEFLSSFLDKGRMRPLLEQLSVQVVVNAQVGLRGAARYAANLL
HHHCCHHHHHHHHCCCCHHHHHHCCEEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA