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The map label for this gene is bioH [H]

Identifier: 86608362

GI number: 86608362

Start: 909611

End: 910528

Strand: Reverse

Name: bioH [H]

Synonym: CYB_0881

Alternate gene names: 86608362

Gene position: 910528-909611 (Counterclockwise)

Preceding gene: 86608363

Following gene: 86608357

Centisome position: 29.89

GC content: 62.53

Gene sequence:

>918_bases
ATGCCTACAGCAGTCGGGAACTGCACTGCTGACGCGATGGGCCTGCAGCTCCACTACCGTACTTGGGGAAAAGGGATCCC
CTCCCTCCCAATCTTGATGCTCCACGGCCATCCGGGCAATGCCGACTGCATGGCGGTATTTGCAGAGGCAGTGGCGGGGA
TCCACCCCTGTGTGGCGCCAGATCTGCGTGGCTACGGGCATTCCCAGGTGACGGATCCCTTTGAGATGGAGGAGCACCTG
GAGGATTTGGAATTACTGCTCAATCGCCTGGGCTGGCAGGAGTGTCTGGTGCTGGGCTGGTCCTTGGGCGGGATCCTGGC
CCTGGAGTTGGCTTTGCGTCTGCCGCAGCGGGTAAAGGGTTTGGTCTTGGTGGCCAGTGCCGCCTACCCCCGCAGCAACC
ATCCCCCCACCGATTTTTGGGATCAGATCAACACCGGCGTTGCCTCGCTGCTCAACTGGCTTTGGCCCGGCTGGGAATGG
AACATCGAGACCTTTGGCCGTCGCTCCCTTTACCGCTACCTGATGCAGCAACAGACCCCAACGGCCTATCGGTATTTGGC
GCACATGGCCTTGCCCGCCTATCTGCACACCTCCCCCCAGGCTCGCCAAGCTCTGCGCGCCGCTTTGCAACGGGGCTACA
ACCGCGAGGGAGATCTGCACCGAATTCGCATCCCGGTACTGCTTATGGCCGGCGAGCGGGATCGCCACATCACCGCCAAC
AGCAGCCTGGCCACAGCCCGCGCCCTGCCCCACTGCACCTGCATTGTCTATCCCAACGTGGCTCATCTCTTTCCCTGGGA
GATCCCCGACCGGGTGGGACAGGATCTGCGCCGCTGGCTCAGCGCTCAAGACTGGGCAAGTGAGATCCCGGTGGTTGGCT
CTTCCGCTTCCTCTGCAGACAAGGCGGCAGAAGCCTGA

Upstream 100 bases:

>100_bases
TCAAAACTTAATTTGCATTCCCAACGGGGTAAAGCTCCAGCCCACTCCGAAGAAGGCGGCCAGCGCCTAACCCTGCTGTC
TAGATGTTATCCAGAGTGTT

Downstream 100 bases:

>100_bases
CCCTGGGCCAACTTCCGCAGCCGGGCAAAGGCCTCTTCCTCTAGATGGATCTGCTGCTGCTGTTGTTCTTCTGGGGTGCG
CAGGCGCTTTCCCAACGGCT

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPTAVGNCTADAMGLQLHYRTWGKGIPSLPILMLHGHPGNADCMAVFAEAVAGIHPCVAPDLRGYGHSQVTDPFEMEEHL
EDLELLLNRLGWQECLVLGWSLGGILALELALRLPQRVKGLVLVASAAYPRSNHPPTDFWDQINTGVASLLNWLWPGWEW
NIETFGRRSLYRYLMQQQTPTAYRYLAHMALPAYLHTSPQARQALRAALQRGYNREGDLHRIRIPVLLMAGERDRHITAN
SSLATARALPHCTCIVYPNVAHLFPWEIPDRVGQDLRRWLSAQDWASEIPVVGSSASSADKAAEA

Sequences:

>Translated_305_residues
MPTAVGNCTADAMGLQLHYRTWGKGIPSLPILMLHGHPGNADCMAVFAEAVAGIHPCVAPDLRGYGHSQVTDPFEMEEHL
EDLELLLNRLGWQECLVLGWSLGGILALELALRLPQRVKGLVLVASAAYPRSNHPPTDFWDQINTGVASLLNWLWPGWEW
NIETFGRRSLYRYLMQQQTPTAYRYLAHMALPAYLHTSPQARQALRAALQRGYNREGDLHRIRIPVLLMAGERDRHITAN
SSLATARALPHCTCIVYPNVAHLFPWEIPDRVGQDLRRWLSAQDWASEIPVVGSSASSADKAAEA
>Mature_304_residues
PTAVGNCTADAMGLQLHYRTWGKGIPSLPILMLHGHPGNADCMAVFAEAVAGIHPCVAPDLRGYGHSQVTDPFEMEEHLE
DLELLLNRLGWQECLVLGWSLGGILALELALRLPQRVKGLVLVASAAYPRSNHPPTDFWDQINTGVASLLNWLWPGWEWN
IETFGRRSLYRYLMQQQTPTAYRYLAHMALPAYLHTSPQARQALRAALQRGYNREGDLHRIRIPVLLMAGERDRHITANS
SLATARALPHCTCIVYPNVAHLFPWEIPDRVGQDLRRWLSAQDWASEIPVVGSSASSADKAAEA

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 33977; Mature: 33846

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTAVGNCTADAMGLQLHYRTWGKGIPSLPILMLHGHPGNADCMAVFAEAVAGIHPCVAP
CCCCCCCCCHHHHCEEEEEHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
DLRGYGHSQVTDPFEMEEHLEDLELLLNRLGWQECLVLGWSLGGILALELALRLPQRVKG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
LVLVASAAYPRSNHPPTDFWDQINTGVASLLNWLWPGWEWNIETFGRRSLYRYLMQQQTP
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCCC
TAYRYLAHMALPAYLHTSPQARQALRAALQRGYNREGDLHRIRIPVLLMAGERDRHITAN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCEEECC
SSLATARALPHCTCIVYPNVAHLFPWEIPDRVGQDLRRWLSAQDWASEIPVVGSSASSAD
CCHHHHHCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
KAAEA
HHCCC
>Mature Secondary Structure 
PTAVGNCTADAMGLQLHYRTWGKGIPSLPILMLHGHPGNADCMAVFAEAVAGIHPCVAP
CCCCCCCCHHHHCEEEEEHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
DLRGYGHSQVTDPFEMEEHLEDLELLLNRLGWQECLVLGWSLGGILALELALRLPQRVKG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
LVLVASAAYPRSNHPPTDFWDQINTGVASLLNWLWPGWEWNIETFGRRSLYRYLMQQQTP
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHCCCC
TAYRYLAHMALPAYLHTSPQARQALRAALQRGYNREGDLHRIRIPVLLMAGERDRHITAN
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCCEEECC
SSLATARALPHCTCIVYPNVAHLFPWEIPDRVGQDLRRWLSAQDWASEIPVVGSSASSAD
CCHHHHHCCCCEEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
KAAEA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA