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The map label for this gene is panE-1 [C]

Identifier: 86608338

GI number: 86608338

Start: 889880

End: 890854

Strand: Direct

Name: panE-1 [C]

Synonym: CYB_0856

Alternate gene names: 86608338

Gene position: 889880-890854 (Clockwise)

Preceding gene: 86608337

Following gene: 86608339

Centisome position: 29.21

GC content: 61.33

Gene sequence:

>975_bases
ATGAAGATTTGTATCGTTGGCGCTGGGGCGGTGGGAAGTCACTTGGCCATATGCCTGGCTCGGTCTGGCTTTCCCGTCAG
TGTCGTGGCCCGTGGAGCTCACCTGCAGGCCATCCGCACCCAAGGTCTGAAGCTCATCCGGCAGGGGGATCCCTCCCAAA
CCTGGGTAGAGCGGTTGACAGCCACCGACGATCCGGCTGCCCTGGGCCCACAGGACTGGCTGATAGTGACGGTCAAGGCC
CACAGCTTGCCGCAGCTTGCCCCTCGACTGGGATCCCTGTGTGGCCCCGACACCCCCATTGTGATTGCCCAGAATGGTAT
CCCCTGGTGGTACTTCTACCGGCATGGCGGCGAGTTTGAGGGGCATTCCCTGACTTCCGTGGATCCAGAAGGGGTTATCG
CTGCTCATTTGCCGATAGAGCGGGTGATTGGCTGTGTGGTGTACATTGCCGTGCAGTTGGCAGAGCCGGGAGTGGTCTTG
CACACAGGGGGTGGGCGCTACATTCTGGGGGAGCCGGATGGATCCCTGTCAGGACGGCTGCAGTCCTTGGCCGCCATCTT
TGAACAGGCGCAGCTTTCCACCACTCTCACCTCGCAGATTCGGGCCGAGATCTGGCAGAAACTGTGGGGCAATGCCGCCT
TCAATCCCATCAGCGCCCTCACCCGGGCTGCTCAAGATGAGATCGCTCAGTACCCACCCACCCGTGCTTTGGTTCGGTCG
GTGATGCGGGAAGTTGAGGCTGTAGCCCAAGCTCTGGGGATCCGGCTGCCGGTCTCTTTGGAAGAGCGGCTAGAAGATGC
AGCCCGCGTGGGATCCCATCGCACCTCGATGCTGCAGGATGTTGAGCTGGGGCGACGGACGGAGATCGAGGCCATTGTGG
GAGCCATCACCGAGTTGGGGCGTTTGGTGGGGGTGCCCACTCCCCATTTGGATACTCTGTATGCTTGCGTCAAGCTGCTG
GAGCGCTCTCTTTAG

Upstream 100 bases:

>100_bases
TTCTCCCGGGCCCGGTATCGGGCCTTGTTACAGCTCCATGTCAATTCCATGTCAATTGGCCACCTGGATATGAGGTGGGT
GGCGGAAAGATGATAAACTC

Downstream 100 bases:

>100_bases
GCTCTTGCAGGGAGCGGTAGGGTCGCTACCGAACGGCAGAGAAACGATTCGTTTGCTGGATCCCAGGCTCCCCCCTGGGG
AAGTGGCTCGAACTCTAGAA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKICIVGAGAVGSHLAICLARSGFPVSVVARGAHLQAIRTQGLKLIRQGDPSQTWVERLTATDDPAALGPQDWLIVTVKA
HSLPQLAPRLGSLCGPDTPIVIAQNGIPWWYFYRHGGEFEGHSLTSVDPEGVIAAHLPIERVIGCVVYIAVQLAEPGVVL
HTGGGRYILGEPDGSLSGRLQSLAAIFEQAQLSTTLTSQIRAEIWQKLWGNAAFNPISALTRAAQDEIAQYPPTRALVRS
VMREVEAVAQALGIRLPVSLEERLEDAARVGSHRTSMLQDVELGRRTEIEAIVGAITELGRLVGVPTPHLDTLYACVKLL
ERSL

Sequences:

>Translated_324_residues
MKICIVGAGAVGSHLAICLARSGFPVSVVARGAHLQAIRTQGLKLIRQGDPSQTWVERLTATDDPAALGPQDWLIVTVKA
HSLPQLAPRLGSLCGPDTPIVIAQNGIPWWYFYRHGGEFEGHSLTSVDPEGVIAAHLPIERVIGCVVYIAVQLAEPGVVL
HTGGGRYILGEPDGSLSGRLQSLAAIFEQAQLSTTLTSQIRAEIWQKLWGNAAFNPISALTRAAQDEIAQYPPTRALVRS
VMREVEAVAQALGIRLPVSLEERLEDAARVGSHRTSMLQDVELGRRTEIEAIVGAITELGRLVGVPTPHLDTLYACVKLL
ERSL
>Mature_324_residues
MKICIVGAGAVGSHLAICLARSGFPVSVVARGAHLQAIRTQGLKLIRQGDPSQTWVERLTATDDPAALGPQDWLIVTVKA
HSLPQLAPRLGSLCGPDTPIVIAQNGIPWWYFYRHGGEFEGHSLTSVDPEGVIAAHLPIERVIGCVVYIAVQLAEPGVVL
HTGGGRYILGEPDGSLSGRLQSLAAIFEQAQLSTTLTSQIRAEIWQKLWGNAAFNPISALTRAAQDEIAQYPPTRALVRS
VMREVEAVAQALGIRLPVSLEERLEDAARVGSHRTSMLQDVELGRRTEIEAIVGAITELGRLVGVPTPHLDTLYACVKLL
ERSL

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34865; Mature: 34865

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKICIVGAGAVGSHLAICLARSGFPVSVVARGAHLQAIRTQGLKLIRQGDPSQTWVERLT
CEEEEEECCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ATDDPAALGPQDWLIVTVKAHSLPQLAPRLGSLCGPDTPIVIAQNGIPWWYFYRHGGEFE
CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCC
GHSLTSVDPEGVIAAHLPIERVIGCVVYIAVQLAEPGVVLHTGGGRYILGEPDGSLSGRL
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHH
QSLAAIFEQAQLSTTLTSQIRAEIWQKLWGNAAFNPISALTRAAQDEIAQYPPTRALVRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
VMREVEAVAQALGIRLPVSLEERLEDAARVGSHRTSMLQDVELGRRTEIEAIVGAITELG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RLVGVPTPHLDTLYACVKLLERSL
HHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKICIVGAGAVGSHLAICLARSGFPVSVVARGAHLQAIRTQGLKLIRQGDPSQTWVERLT
CEEEEEECCCHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ATDDPAALGPQDWLIVTVKAHSLPQLAPRLGSLCGPDTPIVIAQNGIPWWYFYRHGGEFE
CCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCC
GHSLTSVDPEGVIAAHLPIERVIGCVVYIAVQLAEPGVVLHTGGGRYILGEPDGSLSGRL
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCCHHHHH
QSLAAIFEQAQLSTTLTSQIRAEIWQKLWGNAAFNPISALTRAAQDEIAQYPPTRALVRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
VMREVEAVAQALGIRLPVSLEERLEDAARVGSHRTSMLQDVELGRRTEIEAIVGAITELG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RLVGVPTPHLDTLYACVKLLERSL
HHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]