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The map label for this gene is pcbC [H]

Identifier: 86608279

GI number: 86608279

Start: 820613

End: 821581

Strand: Direct

Name: pcbC [H]

Synonym: CYB_0795

Alternate gene names: 86608279

Gene position: 820613-821581 (Clockwise)

Preceding gene: 86608268

Following gene: 86608280

Centisome position: 26.93

GC content: 57.89

Gene sequence:

>969_bases
ATGGCAACCACTCCCCAACGCCAGACTCTGCCGGTTGTCGATTTTGCCGCCTTTCAGAAAGGAACGGCAGGTGAGCGGGA
GCAGTTTGTCCGCCAGGTGGGGGAAGCCCTGCAACAGATTGGCTTTTTTGCCTTGGTTAACCATGGCCTATCGCCGGAAT
TGATCCGGGAAGCCTATGAAGCCGCAGAAGCCGTTTTTCTTTTGCCAGAGCCAACCAAGAGAGCCTATGAGGATCCGGCG
CTGCTGGGGCAACGAGGGTACACCCCCTTTGGCAAAGAACACGCTAAAGATCATCCCTATCCTGACATGAAAGAGTTTTG
GCACATCGGGCGCGAAGGGGATCCCCACCTTCCTGCCAACATCTGGCCTCGGGAGGTGCCCCAATTTCGCAGGGTGATGG
TAGAGCTGTTCGCCCAACTGGAAACCTGTGCCCAGGGCCTGTTGCAGGCGGTCTCTCTGTATCTGGGGGAGCTTGCCGAA
TACTTGCCCAAAGCGGTGGAAGGAGGAGCCAATCTCTTGCGGGTGATTCATTATCCGCCGATCCCTGCTGAAGCCCCTCC
CCAGAGTTTACGAGCTGCAGCCCATGAAGACATCAACTTGATTACGCTCTTGTGTGAAGCCACCGCACCAGGTCTAGAGC
TTCTGCAACGAGATGGATCTTGGCTGCCCATTTCGGCCCTCCCTGGTCAGATCATTGTCGATGCTGGGGATATGCTGCAA
AACCTCACCAATGGCCTGTTGCGCAGCACCACCCATCGGGTGACCAACCCCGACAACCCTCAAGAATGCCGCTTTTCCAT
TCCCTTCTTTGTGCATCCGCGGCCAGAGGTGGATCTCACGCCCTTGCCGACTTGTGTGGCCCGCACCGGCGGGATCCCTC
GGTTCCCTTCCCTGACTGGCGGAGAATACTTGGCCCAGCGGTTGAGGGAAATTGGCCTGGCCGAGGCAGGATCCCCGCCC
CAGCATTGA

Upstream 100 bases:

>100_bases
GATTCAGAACTCTCCCCTTGGCTTCTTAGGAAGGATAGCATAGGGTACCAAGCCCGCTGCCTGAGAAAGTGTTGACTTTC
CACCAGAGACGACTTCTGCC

Downstream 100 bases:

>100_bases
TCCCAACTGGGGGTCTCTATGTTTCGGATCCCGGCCTTGCCCTACGAGTATGAAGTTCCCAGCCTGTCTCAGTTGGCCCT
GGTGATCATCGATATGCAGC

Product: 2OG-Fe(II) oxygenase family oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MATTPQRQTLPVVDFAAFQKGTAGEREQFVRQVGEALQQIGFFALVNHGLSPELIREAYEAAEAVFLLPEPTKRAYEDPA
LLGQRGYTPFGKEHAKDHPYPDMKEFWHIGREGDPHLPANIWPREVPQFRRVMVELFAQLETCAQGLLQAVSLYLGELAE
YLPKAVEGGANLLRVIHYPPIPAEAPPQSLRAAAHEDINLITLLCEATAPGLELLQRDGSWLPISALPGQIIVDAGDMLQ
NLTNGLLRSTTHRVTNPDNPQECRFSIPFFVHPRPEVDLTPLPTCVARTGGIPRFPSLTGGEYLAQRLREIGLAEAGSPP
QH

Sequences:

>Translated_322_residues
MATTPQRQTLPVVDFAAFQKGTAGEREQFVRQVGEALQQIGFFALVNHGLSPELIREAYEAAEAVFLLPEPTKRAYEDPA
LLGQRGYTPFGKEHAKDHPYPDMKEFWHIGREGDPHLPANIWPREVPQFRRVMVELFAQLETCAQGLLQAVSLYLGELAE
YLPKAVEGGANLLRVIHYPPIPAEAPPQSLRAAAHEDINLITLLCEATAPGLELLQRDGSWLPISALPGQIIVDAGDMLQ
NLTNGLLRSTTHRVTNPDNPQECRFSIPFFVHPRPEVDLTPLPTCVARTGGIPRFPSLTGGEYLAQRLREIGLAEAGSPP
QH
>Mature_321_residues
ATTPQRQTLPVVDFAAFQKGTAGEREQFVRQVGEALQQIGFFALVNHGLSPELIREAYEAAEAVFLLPEPTKRAYEDPAL
LGQRGYTPFGKEHAKDHPYPDMKEFWHIGREGDPHLPANIWPREVPQFRRVMVELFAQLETCAQGLLQAVSLYLGELAEY
LPKAVEGGANLLRVIHYPPIPAEAPPQSLRAAAHEDINLITLLCEATAPGLELLQRDGSWLPISALPGQIIVDAGDMLQN
LTNGLLRSTTHRVTNPDNPQECRFSIPFFVHPRPEVDLTPLPTCVARTGGIPRFPSLTGGEYLAQRLREIGLAEAGSPPQ
H

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI85816264, Length=275, Percent_Identity=24.7272727272727, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28572124, Length=297, Percent_Identity=25.9259259259259, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 35562; Mature: 35431

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTPQRQTLPVVDFAAFQKGTAGEREQFVRQVGEALQQIGFFALVNHGLSPELIREAYE
CCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAEAVFLLPEPTKRAYEDPALLGQRGYTPFGKEHAKDHPYPDMKEFWHIGREGDPHLPAN
HHHEEEECCCCHHHHHCCHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHCCCCCCCCCCCC
IWPREVPQFRRVMVELFAQLETCAQGLLQAVSLYLGELAEYLPKAVEGGANLLRVIHYPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCC
IPAEAPPQSLRAAAHEDINLITLLCEATAPGLELLQRDGSWLPISALPGQIIVDAGDMLQ
CCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCEEECCCCCCCEEECHHHHHH
NLTNGLLRSTTHRVTNPDNPQECRFSIPFFVHPRPEVDLTPLPTCVARTGGIPRFPSLTG
HHHHHHHHHHHHCCCCCCCHHHCEEECCEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCC
GEYLAQRLREIGLAEAGSPPQH
HHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ATTPQRQTLPVVDFAAFQKGTAGEREQFVRQVGEALQQIGFFALVNHGLSPELIREAYE
CCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAEAVFLLPEPTKRAYEDPALLGQRGYTPFGKEHAKDHPYPDMKEFWHIGREGDPHLPAN
HHHEEEECCCCHHHHHCCHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHCCCCCCCCCCCC
IWPREVPQFRRVMVELFAQLETCAQGLLQAVSLYLGELAEYLPKAVEGGANLLRVIHYPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCC
IPAEAPPQSLRAAAHEDINLITLLCEATAPGLELLQRDGSWLPISALPGQIIVDAGDMLQ
CCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHCCCCEEECCCCCCCEEECHHHHHH
NLTNGLLRSTTHRVTNPDNPQECRFSIPFFVHPRPEVDLTPLPTCVARTGGIPRFPSLTG
HHHHHHHHHHHHCCCCCCCHHHCEEECCEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCC
GEYLAQRLREIGLAEAGSPPQH
HHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1901702 [H]