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The map label for this gene is ccdA [H]

Identifier: 86608114

GI number: 86608114

Start: 635075

End: 635824

Strand: Direct

Name: ccdA [H]

Synonym: CYB_0625

Alternate gene names: 86608114

Gene position: 635075-635824 (Clockwise)

Preceding gene: 86608113

Following gene: 86608115

Centisome position: 20.84

GC content: 59.87

Gene sequence:

>750_bases
ATGTTGAATGCGGCTCAGCTCTGGCTTTACCACCTAGAACAATGGGCAACTGAGCTGGTTCAGTTTCAACTGCAGCACCT
TTCTCCCGTTAGTCTGTTGGTGGTGGGTCTGGCGGGCTTGCTCACCAGTCTTTCCCCCTGCACGTTGTCTATGCTGCCGG
TGACCATCGGCTACATCGGCGGCTACACCCCCGCTTCTGAGGAAACGGCTGGGGAAGGGCGGTGGCAAGTTTGGGCTCAA
TCTTTGGGTTTTGCGGCTGGGGTGGCTTTTACCCTGACCCTGCTGGGTTTGTCGGCAGCTTTGCTGGGTCGCGTTTACGG
ACAAACCGGATCCTTCGGGCCTGTTGTGGTGGGGGGAATTGCTATTTTGATGGGGCTGAACTTGTTGGAGGTGATCCCCC
TGCGTTTTCCCGATTGGTTTAACCGCCTCGAGATTCCCGGAGAATGGCCCAGGCTGGGTCGGGCAGTGTTGCTGGGGTTA
ACCTTTGGCCTGGTGGCCTCTCCCTGCAGTACGCCGGTTTTGGTGGCTTTGCTGGCCTGGGTTTCCACCACAGGGCAACC
CTGGGTAGGGGGTGGGCTGTTGCTGGCTTACGGGCTGGGGTTGGCCTTTCCCCTGCTCCTGGCGGGGGTGTTTACCGGGT
TGGTGAAGCAACTGTTGGCCCTGCGGCGCTGGTCGGGCTGGCTCACTTATGCCAGTGGGGTGGTGTTGGTGGGGTTCGGC
AGCGTAACGATCCTGTCGGCCTGGGTCTAA

Upstream 100 bases:

>100_bases
TTCTCCACAACCTGGGCGGTGGGAATGGATAGCAAAGATATCTTGAACGGGCTCGGGGATCCTTCATGCTACCTTGGGCT
TATGTTGACAGATTGAGCTT

Downstream 100 bases:

>100_bases
GGGATCCCTGCTGCTGCAGGCTAAGATGGGGCTACACCTACAGCACCCTGTTGGGGACTGCACCTTGCCTGGCAAGAGCA
GCGGTCTGAATCTTGAGCCG

Product: cytochrome c biogenesis membrane protein

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLNAAQLWLYHLEQWATELVQFQLQHLSPVSLLVVGLAGLLTSLSPCTLSMLPVTIGYIGGYTPASEETAGEGRWQVWAQ
SLGFAAGVAFTLTLLGLSAALLGRVYGQTGSFGPVVVGGIAILMGLNLLEVIPLRFPDWFNRLEIPGEWPRLGRAVLLGL
TFGLVASPCSTPVLVALLAWVSTTGQPWVGGGLLLAYGLGLAFPLLLAGVFTGLVKQLLALRRWSGWLTYASGVVLVGFG
SVTILSAWV

Sequences:

>Translated_249_residues
MLNAAQLWLYHLEQWATELVQFQLQHLSPVSLLVVGLAGLLTSLSPCTLSMLPVTIGYIGGYTPASEETAGEGRWQVWAQ
SLGFAAGVAFTLTLLGLSAALLGRVYGQTGSFGPVVVGGIAILMGLNLLEVIPLRFPDWFNRLEIPGEWPRLGRAVLLGL
TFGLVASPCSTPVLVALLAWVSTTGQPWVGGGLLLAYGLGLAFPLLLAGVFTGLVKQLLALRRWSGWLTYASGVVLVGFG
SVTILSAWV
>Mature_249_residues
MLNAAQLWLYHLEQWATELVQFQLQHLSPVSLLVVGLAGLLTSLSPCTLSMLPVTIGYIGGYTPASEETAGEGRWQVWAQ
SLGFAAGVAFTLTLLGLSAALLGRVYGQTGSFGPVVVGGIAILMGLNLLEVIPLRFPDWFNRLEIPGEWPRLGRAVLLGL
TFGLVASPCSTPVLVALLAWVSTTGQPWVGGGLLLAYGLGLAFPLLLAGVFTGLVKQLLALRRWSGWLTYASGVVLVGFG
SVTILSAWV

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=193, Percent_Identity=30.5699481865285, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 26374; Mature: 26374

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAAQLWLYHLEQWATELVQFQLQHLSPVSLLVVGLAGLLTSLSPCTLSMLPVTIGYIG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GYTPASEETAGEGRWQVWAQSLGFAAGVAFTLTLLGLSAALLGRVYGQTGSFGPVVVGGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AILMGLNLLEVIPLRFPDWFNRLEIPGEWPRLGRAVLLGLTFGLVASPCSTPVLVALLAW
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VSTTGQPWVGGGLLLAYGLGLAFPLLLAGVFTGLVKQLLALRRWSGWLTYASGVVLVGFG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEECC
SVTILSAWV
HHHHHHHCC
>Mature Secondary Structure
MLNAAQLWLYHLEQWATELVQFQLQHLSPVSLLVVGLAGLLTSLSPCTLSMLPVTIGYIG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
GYTPASEETAGEGRWQVWAQSLGFAAGVAFTLTLLGLSAALLGRVYGQTGSFGPVVVGGI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AILMGLNLLEVIPLRFPDWFNRLEIPGEWPRLGRAVLLGLTFGLVASPCSTPVLVALLAW
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VSTTGQPWVGGGLLLAYGLGLAFPLLLAGVFTGLVKQLLALRRWSGWLTYASGVVLVGFG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEEECC
SVTILSAWV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]