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The map label for this gene is clpP [H]

Identifier: 86608099

GI number: 86608099

Start: 621483

End: 622094

Strand: Direct

Name: clpP [H]

Synonym: CYB_0610

Alternate gene names: 86608099

Gene position: 621483-622094 (Clockwise)

Preceding gene: 86608098

Following gene: 86608100

Centisome position: 20.4

GC content: 57.03

Gene sequence:

>612_bases
ATGCCGATTGGAGTGCCTCGGGTTCCCTACCGTTTGCCCGGCGAGCCCTATAGCCAGTGGATTAGCCTTGACGATCGCCT
GTACCAAGAGCGGATTTTGTTTATCGGCGAGCCCATTGACGATAGCTTGGCCAATACCATCGTGGGGGTGATGCTCTACC
TCAACTCGCAGGATCCGCAAAAGGACATTGTGATGTACATCAATTCTCCCGGTGGCTCTGTGACGGCGGGCATGGCCATC
TACGACACCATGAACCACATCAAGCCAGATATCGTTACGGTTTGCGTGGGCCAAGCAGCTTCAATGGGAGCCTTTTTGTT
GGCTGCTGGCACCAAGGGCAAGCGGTTTGCCCTGCCCCACTCCCGCATCATGCTGCACCAGCCTTCTCTGGGCACGATCC
AAGGCCAAGCCAGCGACATTGAAATTCGCGCCCGCGAAACTCTGCGAGTCAAACGACGCATGAACGAGATCTTGGCGCAA
ACCACCGGCCAACCGCTGGAGAAAATCGAGCGGGATGTGGAGCGAGACTTTTACCTCTCGGCCACGGAAGCTCAGGCTTA
CGGCATCGTGGATCGGGTGATCCAAGAGCGCTCGGAAGCCATGGCCAGCTAA

Upstream 100 bases:

>100_bases
GGACGCATTGTTTCCTCGGTTTTGCCCCAGCTGGATTTGAGCGCGGAAGATATCTTACAAGCGCGTCGTTCTGTGTTTCA
TACTTTGCCAGGAGAAACTT

Downstream 100 bases:

>100_bases
AGGGATCCCCCCCTTTCCCCCAGCAACAGGTCGAGGGGTTGGGAAAGGTTGGGAGGGATCCCTTCAAGGGGTGGAGTTCA
GTGGACAACGCTAGGAGAAC

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 1 [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MPIGVPRVPYRLPGEPYSQWISLDDRLYQERILFIGEPIDDSLANTIVGVMLYLNSQDPQKDIVMYINSPGGSVTAGMAI
YDTMNHIKPDIVTVCVGQAASMGAFLLAAGTKGKRFALPHSRIMLHQPSLGTIQGQASDIEIRARETLRVKRRMNEILAQ
TTGQPLEKIERDVERDFYLSATEAQAYGIVDRVIQERSEAMAS

Sequences:

>Translated_203_residues
MPIGVPRVPYRLPGEPYSQWISLDDRLYQERILFIGEPIDDSLANTIVGVMLYLNSQDPQKDIVMYINSPGGSVTAGMAI
YDTMNHIKPDIVTVCVGQAASMGAFLLAAGTKGKRFALPHSRIMLHQPSLGTIQGQASDIEIRARETLRVKRRMNEILAQ
TTGQPLEKIERDVERDFYLSATEAQAYGIVDRVIQERSEAMAS
>Mature_202_residues
PIGVPRVPYRLPGEPYSQWISLDDRLYQERILFIGEPIDDSLANTIVGVMLYLNSQDPQKDIVMYINSPGGSVTAGMAIY
DTMNHIKPDIVTVCVGQAASMGAFLLAAGTKGKRFALPHSRIMLHQPSLGTIQGQASDIEIRARETLRVKRRMNEILAQT
TGQPLEKIERDVERDFYLSATEAQAYGIVDRVIQERSEAMAS

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=170, Percent_Identity=54.7058823529412, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1786641, Length=173, Percent_Identity=62.4277456647399, Blast_Score=232, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17538017, Length=168, Percent_Identity=51.7857142857143, Blast_Score=176, Evalue=5e-45,
Organism=Drosophila melanogaster, GI20129427, Length=178, Percent_Identity=46.6292134831461, Blast_Score=172, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22566; Mature: 22435

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00381 CLP_PROTEASE_SER ; PS00382 CLP_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIGVPRVPYRLPGEPYSQWISLDDRLYQERILFIGEPIDDSLANTIVGVMLYLNSQDPQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHEECCCCCC
KDIVMYINSPGGSVTAGMAIYDTMNHIKPDIVTVCVGQAASMGAFLLAAGTKGKRFALPH
CEEEEEEECCCCCEEHHHHHHHHHHHCCCHHEEHHHCCCCCCCEEEEEECCCCCEEECCC
SRIMLHQPSLGTIQGQASDIEIRARETLRVKRRMNEILAQTTGQPLEKIERDVERDFYLS
CEEEEECCCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEE
ATEAQAYGIVDRVIQERSEAMAS
CCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PIGVPRVPYRLPGEPYSQWISLDDRLYQERILFIGEPIDDSLANTIVGVMLYLNSQDPQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHEECCCCCC
KDIVMYINSPGGSVTAGMAIYDTMNHIKPDIVTVCVGQAASMGAFLLAAGTKGKRFALPH
CEEEEEEECCCCCEEHHHHHHHHHHHCCCHHEEHHHCCCCCCCEEEEEECCCCCEEECCC
SRIMLHQPSLGTIQGQASDIEIRARETLRVKRRMNEILAQTTGQPLEKIERDVERDFYLS
CEEEEECCCCCEECCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEE
ATEAQAYGIVDRVIQERSEAMAS
CCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA